18-MC acts in the medial habenula and interpeduncular nucleus to attenuate dopamine sensitization to morphine in the nucleus accumbens

Synapse

Volumn 61, Issue 7, 2007, Pages 547-560

  Taraschenko, Olga D ^a   Shulan, Joseph M ^a   Maisonneuve, Isabelle M ^a   Glick, Stanley D ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

Author keywords

Drug addiction; Habenulo interpeduncular pathway; Mesolimbic pathway; Opioids

Indexed keywords

18 METHOXYCORONARIDINE; MORPHINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; HABENULA; INTERPEDUNCULAR NUCLEUS; MESOLIMBIC DOPAMINERGIC SYSTEM; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; SENSITIZATION;

3,4-DIHYDROXYPHENYLACETIC ACID; ANALYSIS OF VARIANCE; ANIMALS; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION ROUTES; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; FEMALE; HOMOVANILLIC ACID; IBOGAINE; MESENCEPHALON; MORPHINE; NARCOTICS; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 34248532064     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20396     Document Type: Article

References (39)

1. Atweh SF, Kuhar MJ. 1977. Autoradiographic localization of opiate receptors in rat brain. II. The brain stem. Brain Res 129:1-12.
2. Blander A, wise RA. 1989. Anatomical mapping of brain stimulation reward sites in the anterior hypothalamic area: Special attention to the stria medullaris. Brain Res 483:12-16.
3. Borg PJ, Taylor DA. 1997. Involvement of μ- and Δ-opioid receptors in the effects of systemic and locally perfused morphine on extracellular levels of dopamine, DOPAC and HVA in the nucleus accumbens of the halothane-anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol 355:582-588.
4. Bot G, Chahl LA. 1996. Induction of Fos-like immunoreactivity by opioids in guinea-pig brain. Brain Res 731:45-56.
5. Ellison G. 1994. Stimulant-induced psychosis, the dopamine theory of schizophrenia, and the habenula. Brain Res Brain Res Rev 19:223-239.
6. Ellison G. 2002. Neural degeneration following chronic stimulant abuse reveals a weak link in brain, fasciculus retroflexus, implying the loss of forebrain control circuitry. Eur Neuropsychopharmacol 12:287-297.
7. Girod R, Role LW. 2001. Long-lasting enhancement of glutamatergic synaptic transmission by acetylcholine contrasts with response adaptation after exposure to low-level nicotine. J Neurosci 21:5182-5190.
8. Glick SD, Dong N, Keller RW, Jr, Carlson JN. 1994. Estimating extracellular concentrations of dopamine and 3,4-dihydroxyphenylacetic acid in nucleus accumbens and striatum using microdialysis: Relationships between in vitro and in vivo recoveries. J Neurochem 62:2017-2021.
9. Glick SD, Kuehne ME, Maisonneuve IM, Bandarage UK, Molinari HH. 1996. 18-Methoxycoronaridine, a nontoxic iboga alkaloid congener: Effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats. Brain Res 719:29-35.
10. Glick SD, Maisonneuve IM, Dickinson HA. 2000. 18-MC reduces methamphetamine and nicotine self-administration in rats. Neuroreport 11:2013-2015.
11. Glick SD, Maisonneuve IM, Szumlinski KK. 2001. Mechanisms of action of ibogaine: Relevance to putative therapeutic effects and development of a safer iboga alkaloid congener. Alkaloids Chem Biol 56:39-53.
12. Glick SD, Maisonneuve IM, Kitchen BA, Fleck MW. 2002. Antagonism of α3β4 nicotinic receptors as a strategy to reduce opioid and stimulant self-administration. Eur J Pharmacol 438:99-105.
13. Glick SD, Ramirez RL, Livi JM, Maisonneuve IM. 2006. 18- Methoxycoronaridine acts in the medial habenula and/or interpeduncular nucleus to decrease morphine self-administration in rats. Eur J Pharmacol 537:94-98.
14. Gotti C, Zoli M, Clementi F. 2006. Brain nicotinic acetylcholine receptors: Native subtypes and their relevance. Trends Pharmacol Sci 27:482-491.
15. Hyman SE, Malenka RC, Nestler EJ. 2006. Neural mechanisms of addiction: The role of reward-related learning and memory. Annu Rev Neurosci 29:565-598.
16. Johnson SW, North RA. 1992. Opioids excite dopamine neurons by hyperpolarization of local interneurons. J Neurosci 12:483-488.
17. Klink R, de Kerchove DA, Zoli M, Changeux JP. 2001. Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei. J Neurosci 21:1452-1463.
18. Lena C, Changeux JP, Mulle C. 1993. Evidence for "preterminal" nicotinic receptors on GABAergic axons in the rat interpeduncular nucleus. J Neurosci 13:2680-2688.
19. Maisonneuve IM, Glick SD. 1999. Attenuation of the reinforcing efficacy of morphine by 18-methoxycoronaridine. Eur J Pharmacol 383:15-21.
20. Maisonneuve IM, Glick SD. 2003. Anti-addictive actions of an iboga alkaloid congener: A novel mechanism for a novel treatment. Pharmacol Biochem Behav 75:607-618.
21. Maisonneuve IM, Warner LM, Glick SD. 2001. Biphasic dose-related effects of morphine on dopamine release. Drug Alcohol Depend 65:55-63.
22. McCormick DA, Prince DA. 1987. Acetylcholine causes rapid nicotinic excitation in the medial habenular nucleus of guinea pig, in vitro. J Neurosci 7:742-752.
23. Morley BJ. 1986. The interpeduncular nucleus. Int Rev Neurobiol 28:157-182.
24. Mulle C, Vidal C, Benoit P, Changeux JP. 1991. Existence of different subtypes of nicotinic acetylcholine receptors in the rat habenulo- interpeduncular system. J Neurosci 11:2588-2597.
25. Nishikawa T, Fage D, Scatton B. 1986. Evidence for, and nature of, the tonic inhibitory influence of habenulointerpeduncular pathways upon cerebral dopaminergic transmission in the rat. Brain Res 373:324-336.
26. Paxinos G, Watson C. 1986. The rat brain in stereotaxic coordinates. San Diego, California: Academic Press.
27. Pennartz CM, Groenewegen HJ, Lopes da Silva FH. 1994. The nucleus accumbens as a complex of functionally distinct neuronal ensembles: An integration of behavioural, electrophysiological and anatomical data. Prog Neurobiol 42:719-761.
28. Picciotto MR. 2003. Nicotine as a modulator of behavior: Beyond the inverted U. Trends Pharmacol Sci 24:493-499.
29. Quick MW, Ceballos RM, Kasten M, McIntosh JM, Lester RA. 1999. α3β4 subunit-containing nicotinic receptors dominate function in rat medial habenula neurons. Neuropharmacology 38:769-783.
30. Rho B, Glick SD. 1998. Effects of 18-methoxycoronaridine on acute signs of morphine withdrawal in rats. Neuroreport 9:1283-1285.
31. Robinson TE, Berridge KC. 1993. The neural basis of drug craving: An incentive-sensitization theory of addiction. Brain Res Brain Res Rev 18:247-291.
32. Stewart J. 1992. Neurobiology of conditioning to drugs of abuse. Ann NY Acad Sci 654:335-346.
33. Sutherland RJ. 1982. The dorsal diencephalic conduction system: A review of the anatomy and functions of the habenular complex. Neurosci Biobehav Rev 6:1-13.
34. Szumlinski KK, Maisonneuve IM, Glick SD. 2000. The potential anti-addictive agent, 18-methoxycoronaridine, blocks the sensitized locomotor and dopamine responses produced by repeated morphine treatment. Brain Res 864:13-23.
35. Taraschenko OD, Panchal V, Maisonneuve IM, Glick SD. 2005. Is antagonism of α3β4 nicotinic receptors a strategy to reduce morphine dependence? Eur J Pharmacol 513:207-218.
36. Taraschenko OD, Rubbinaccio HY, Shulan JM, Glick SD, Maisonneuve IM. 2006. Tolerance to the stimulatory and the inhibitory effects of morphine on acetylcholine release in the interpeduncular nucleus in rats. Soc Neurosci. Abstract 482.12
37. Vanderschuren LJ, Kalivas PW. 2000. Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: A critical review of preclinical studies. Psychopharmacology (Berl) 151:99-120.
38. Vertes RP. 2006. Interactions among the medial prefrontal cortex, hippocampus and midline thalamus in emotional and cognitive processing in the rat. Neuroscience 142:1-20.
39. Wonnacott S. 1997. Presynaptic nicotinic ACh receptors. Trends Neurosci 20:92-98.