메뉴 건너뛰기




Volumn 17, Issue 9, 2014, Pages 1146-1152

Reward processing by the lateral habenula in normal and depressive behaviors

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; SEROTONIN;

EID: 84906674545     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3779     Document Type: Review
Times cited : (331)

References (98)
  • 1
    • 2642519680 scopus 로고    scopus 로고
    • Dopamine, learning and motivation
    • Wise, R.A. Dopamine, learning and motivation. Nat. Rev. Neurosci. 5, 483-494 (2004).
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 483-494
    • Wise, R.A.1
  • 2
    • 84883182497 scopus 로고    scopus 로고
    • The brain reward circuitry in mood disorders
    • Russo, S.J. & Nestler, E.J. The brain reward circuitry in mood disorders. Nat. Rev. Neurosci. 14, 609-625 (2013).
    • (2013) Nat. Rev. Neurosci. , vol.14 , pp. 609-625
    • Russo, S.J.1    Nestler, E.J.2
  • 3
    • 78649650717 scopus 로고    scopus 로고
    • Serotonin and dopamine: Unifying affective, activational, and decision functions
    • Cools, R., Nakamura, K. & Daw, N.D. Serotonin and dopamine: unifying affective, activational, and decision functions. Neuropsychopharmacology 36, 98-113 (2011).
    • (2011) Neuropsychopharmacology , vol.36 , pp. 98-113
    • Cools, R.1    Nakamura, K.2    Daw, N.D.3
  • 4
    • 84856367288 scopus 로고    scopus 로고
    • Evolutionary conservation of the habenular nuclei and their circuitry controlling the dopamine and 5-hydroxytryptophan (5-HT) systems
    • Stephenson-Jones, M., Floros, O., Robertson, B. & Grillner, S. Evolutionary conservation of the habenular nuclei and their circuitry controlling the dopamine and 5-hydroxytryptophan (5-HT) systems. Proc. Natl. Acad. Sci. USA 109, 164-173 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 164-173
    • Stephenson-Jones, M.1    Floros, O.2    Robertson, B.3    Grillner, S.4
  • 5
    • 0020024556 scopus 로고
    • The dorsal diencephalic conduction system: A review of the anatomy and functions of the habenular complex
    • Sutherland, R.J. The dorsal diencephalic conduction system: a review of the anatomy and functions of the habenular complex. Neurosci. Biobehav. Rev. 6, 1-13 (1982).
    • (1982) Neurosci. Biobehav. Rev. , vol.6 , pp. 1-13
    • Sutherland, R.J.1
  • 6
    • 27744558550 scopus 로고    scopus 로고
    • Forebrain substrates of reward and motivation
    • Wise, R.A. Forebrain substrates of reward and motivation. J. Comp. Neurol. 493, 115-121 (2005).
    • (2005) J. Comp. Neurol. , vol.493 , pp. 115-121
    • Wise, R.A.1
  • 7
    • 77953791927 scopus 로고    scopus 로고
    • The habenula: From stress evasion to value-based decision-making
    • Hikosaka, O. The habenula: from stress evasion to value-based decision-making. Nat. Rev. Neurosci. 11, 503-513 (2010).
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 503-513
    • Hikosaka, O.1
  • 8
    • 37549022670 scopus 로고    scopus 로고
    • Serotoninergic regulation of emotional and behavioural control processes
    • Cools, R., Roberts, A.C. & Robbins, T.W. Serotoninergic regulation of emotional and behavioural control processes. Trends Cogn. Sci. 12, 31-40 (2008).
    • (2008) Trends Cogn. Sci. , vol.12 , pp. 31-40
    • Cools, R.1    Roberts, A.C.2    Robbins, T.W.3
  • 9
    • 34247637934 scopus 로고    scopus 로고
    • A conductor hidden in the orchestra? Role of the habenular complex in monoamine transmission and cognition
    • Lecourtier, L. & Kelly, P.H. A conductor hidden in the orchestra? Role of the habenular complex in monoamine transmission and cognition. Neurosci. Biobehav. Rev. 31, 658-672 (2007).
    • (2007) Neurosci. Biobehav. Rev. , vol.31 , pp. 658-672
    • Lecourtier, L.1    Kelly, P.H.2
  • 10
    • 70350437997 scopus 로고    scopus 로고
    • Lateral habenula projections to dopamine and GABA neurons in the rat ventral tegmental area
    • Omelchenko, N., Bell, R. & Sesack, S.R. Lateral habenula projections to dopamine and GABA neurons in the rat ventral tegmental area. Eur. J. Neurosci. 30, 1239-1250 (2009).
    • (2009) Eur. J. Neurosci. , vol.30 , pp. 1239-1250
    • Omelchenko, N.1    Bell, R.2    Sesack, S.R.3
  • 11
    • 0018647716 scopus 로고
    • Efferent connections of the habenular nuclei in the rat
    • Herkenham, M. & Nauta, W.J. Efferent connections of the habenular nuclei in the rat. J. Comp. Neurol. 187, 19-47 (1979).
    • (1979) J. Comp. Neurol. , vol.187 , pp. 19-47
    • Herkenham, M.1    Nauta, W.J.2
  • 12
    • 61549112212 scopus 로고    scopus 로고
    • The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses
    • Jhou, T.C., Fields, H.L., Baxter, M.G., Saper, C.B. & Holland, P.C. The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron 61, 786-800 (2009).
    • (2009) Neuron , vol.61 , pp. 786-800
    • Jhou, T.C.1    Fields, H.L.2    Baxter, M.G.3    Saper, C.B.4    Holland, P.C.5
  • 14
    • 0018147788 scopus 로고
    • Serotonin neurons of the midbrain raphe: Ascending projections
    • Moore, R.Y., Halaris, A.E. & Jones, B.E. Serotonin neurons of the midbrain raphe: ascending projections. J. Comp. Neurol. 180, 417-438 (1978).
    • (1978) J. Comp. Neurol. , vol.180 , pp. 417-438
    • Moore, R.Y.1    Halaris, A.E.2    Jones, B.E.3
  • 15
    • 0021140845 scopus 로고
    • Evidence for a dopaminergic innervation of the cat lateral habenula: Its role in controlling serotonin transmission in the basal ganglia
    • Reisine, T.D. et al. Evidence for a dopaminergic innervation of the cat lateral habenula: its role in controlling serotonin transmission in the basal ganglia. Brain Res. 308, 281-288 (1984).
    • (1984) Brain Res. , vol.308 , pp. 281-288
    • Reisine, T.D.1
  • 16
    • 34347343926 scopus 로고    scopus 로고
    • Lateral habenula as a source of negative reward signals in dopamine neurons
    • Matsumoto, M. & Hikosaka, O. Lateral habenula as a source of negative reward signals in dopamine neurons. Nature 447, 1111-1115 (2007).
    • (2007) Nature , vol.447 , pp. 1111-1115
    • Matsumoto, M.1    Hikosaka, O.2
  • 17
    • 58149127270 scopus 로고    scopus 로고
    • Representation of negative motivational value in the primate lateral habenula
    • Matsumoto, M. & Hikosaka, O. Representation of negative motivational value in the primate lateral habenula. Nat. Neurosci. 12, 77-84 (2009).
    • (2009) Nat. Neurosci. , vol.12 , pp. 77-84
    • Matsumoto, M.1    Hikosaka, O.2
  • 18
    • 84868621500 scopus 로고    scopus 로고
    • Input-specific control of reward and aversion in the ventral tegmental area
    • Lammel, S. et al. Input-specific control of reward and aversion in the ventral tegmental area. Nature 491, 212-217 (2012).
    • (2012) Nature , vol.491 , pp. 212-217
    • Lammel, S.1
  • 19
    • 0028047236 scopus 로고
    • Dopamine agonists and stress produce different patterns of Fos-like immunoreactivity in the lateral habenula
    • Wirtshafter, D., Asin, K.E. & Pitzer, M.R. Dopamine agonists and stress produce different patterns of Fos-like immunoreactivity in the lateral habenula. Brain Res. 633, 21-26 (1994).
    • (1994) Brain Res. , vol.633 , pp. 21-26
    • Wirtshafter, D.1    Asin, K.E.2    Pitzer, M.R.3
  • 20
    • 0022621458 scopus 로고
    • Kainate and electrolytic lesions of the lateral habenula: Effect on avoidance responses
    • Wilcox, K.S., Christoph, G.R., Double, B.A. & Leonzio, R.J. Kainate and electrolytic lesions of the lateral habenula: effect on avoidance responses. Physiol. Behav. 36, 413-417 (1986).
    • (1986) Physiol. Behav. , vol.36 , pp. 413-417
    • Wilcox, K.S.1    Christoph, G.R.2    Double, B.A.3    Leonzio, R.J.4
  • 21
    • 40149109071 scopus 로고    scopus 로고
    • Serotonin, inhibition, and negative mood
    • Dayan, P. & Huys, Q.J. Serotonin, inhibition, and negative mood. PLoS Comput. Biol. 4, e4 (2008).
    • (2008) PLoS Comput. Biol. , vol.4
    • Dayan, P.1    Huys, Q.J.2
  • 22
    • 71649109149 scopus 로고    scopus 로고
    • Remission of major depression under deep brain stimulation of the lateral habenula in a therapy-refractory patient
    • Sartorius, A. et al. Remission of major depression under deep brain stimulation of the lateral habenula in a therapy-refractory patient. Biol. Psychiatry 67, 9-11 (2010).
    • (2010) Biol. Psychiatry , vol.67 , pp. 9-11
    • Sartorius, A.1
  • 23
    • 84898738049 scopus 로고    scopus 로고
    • The lateral habenula in addiction and depression: An anatomical, synaptic and behavioral overview
    • Lecca, S., Meye, F.J. & Mameli, M. The lateral habenula in addiction and depression: an anatomical, synaptic and behavioral overview. Eur. J. Neurosci. 39, 1170-1178 (2014).
    • (2014) Eur. J. Neurosci. , vol.39 , pp. 1170-1178
    • Lecca, S.1    Meye, F.J.2    Mameli, M.3
  • 24
    • 0031867046 scopus 로고    scopus 로고
    • Predictive reward signal of dopamine neurons
    • Schultz, W. Predictive reward signal of dopamine neurons. J. Neurophysiol. 80, 1-27 (1998).
    • (1998) J. Neurophysiol. , vol.80 , pp. 1-27
    • Schultz, W.1
  • 25
    • 80051565543 scopus 로고    scopus 로고
    • Negative reward signals from the lateral habenula to dopamine neurons are mediated by rostromedial tegmental nucleus in primates
    • Hong, S., Jhou, T.C., Smith, M., Saleem, K.S. & Hikosaka, O. Negative reward signals from the lateral habenula to dopamine neurons are mediated by rostromedial tegmental nucleus in primates. J. Neurosci. 31, 11457-11471 (2011).
    • (2011) J. Neurosci. , vol.31 , pp. 11457-11471
    • Hong, S.1    Jhou, T.C.2    Smith, M.3    Saleem, K.S.4    Hikosaka, O.5
  • 26
    • 0037459319 scopus 로고    scopus 로고
    • Discrete coding of reward probability and uncertainty by dopamine neurons
    • Fiorillo, C.D., Tobler, P.N. & Schultz, W. Discrete coding of reward probability and uncertainty by dopamine neurons. Science 299, 1898-1902 (2003).
    • (2003) Science , vol.299 , pp. 1898-1902
    • Fiorillo, C.D.1    Tobler, P.N.2    Schultz, W.3
  • 27
    • 77955172369 scopus 로고    scopus 로고
    • Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry
    • Kravitz, A.V. et al. Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry. Nature 466, 622-626 (2010).
    • (2010) Nature , vol.466 , pp. 622-626
    • Kravitz, A.V.1
  • 28
    • 33744971409 scopus 로고    scopus 로고
    • Role of dopamine in the primate caudate nucleus in reward modulation of saccades
    • Nakamura, K. & Hikosaka, O. Role of dopamine in the primate caudate nucleus in reward modulation of saccades. J. Neurosci. 26, 5360-5369 (2006).
    • (2006) J. Neurosci. , vol.26 , pp. 5360-5369
    • Nakamura, K.1    Hikosaka, O.2
  • 29
    • 32444439058 scopus 로고    scopus 로고
    • Behavioral theories and the neurophysiology of reward
    • Schultz, W. Behavioral theories and the neurophysiology of reward. Annu. Rev. Psychol. 57, 87-115 (2006).
    • (2006) Annu. Rev. Psychol. , vol.57 , pp. 87-115
    • Schultz, W.1
  • 30
    • 67349098495 scopus 로고    scopus 로고
    • Two types of dopamine neuron distinctly convey positive and negative motivational signals
    • Matsumoto, M. & Hikosaka, O. Two types of dopamine neuron distinctly convey positive and negative motivational signals. Nature 459, 837-841 (2009).
    • (2009) Nature , vol.459 , pp. 837-841
    • Matsumoto, M.1    Hikosaka, O.2
  • 31
    • 84864890590 scopus 로고
    • Neural organization of the defensive behavior system responsible for fear
    • Fanselow, M.S. Neural organization of the defensive behavior system responsible for fear. Psychon. Bull. Rev. 1, 429-438 (1994).
    • (1994) Psychon. Bull. Rev. , vol.1 , pp. 429-438
    • Fanselow, M.S.1
  • 34
    • 33646149370 scopus 로고    scopus 로고
    • Nociceptive responses of midbrain dopaminergic neurones are modulated by the superior colliculus in the rat
    • Coizet, V., Dommett, E.J., Redgrave, P. & Overton, P.G. Nociceptive responses of midbrain dopaminergic neurones are modulated by the superior colliculus in the rat. Neuroscience 139, 1479-1493 (2006).
    • (2006) Neuroscience , vol.139 , pp. 1479-1493
    • Coizet, V.1    Dommett, E.J.2    Redgrave, P.3    Overton, P.G.4
  • 35
    • 0034061668 scopus 로고    scopus 로고
    • Mesolimbocortical and nigrostriatal dopamine responses to salient non-reward events
    • Horvitz, J.C. Mesolimbocortical and nigrostriatal dopamine responses to salient non-reward events. Neuroscience 96, 651-656 (2000).
    • (2000) Neuroscience , vol.96 , pp. 651-656
    • Horvitz, J.C.1
  • 36
    • 79958055503 scopus 로고    scopus 로고
    • Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli
    • Lammel, S., Ion, D.I., Roeper, J. & Malenka, R.C. Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli. Neuron 70, 855-862 (2011).
    • (2011) Neuron , vol.70 , pp. 855-862
    • Lammel, S.1    Ion, D.I.2    Roeper, J.3    Malenka, R.C.4
  • 37
    • 58149328473 scopus 로고    scopus 로고
    • Habenula: Crossroad between the basal ganglia and the limbic system
    • Hikosaka, O., Sesack, S.R., Lecourtier, L. & Shepard, P.D. Habenula: crossroad between the basal ganglia and the limbic system. J. Neurosci. 28, 11825-11829 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 11825-11829
    • Hikosaka, O.1    Sesack, S.R.2    Lecourtier, L.3    Shepard, P.D.4
  • 38
    • 78650845454 scopus 로고    scopus 로고
    • Electrical stimulation of the lateral habenula produces an inhibitory effect on sucrose self-administration
    • Friedman, A. et al. Electrical stimulation of the lateral habenula produces an inhibitory effect on sucrose self-administration. Neuropharmacology 60, 381-387 (2011).
    • (2011) Neuropharmacology , vol.60 , pp. 381-387
    • Friedman, A.1
  • 39
    • 84879541836 scopus 로고    scopus 로고
    • Electrical stimulation of lateral habenula during learning: Frequency-dependent effects on acquisition but not retrieval of a two-way active avoidance response
    • Ilango, A., Shumake, J., Wetzel, W., Scheich, H. & Ohl, F.W. Electrical stimulation of lateral habenula during learning: frequency-dependent effects on acquisition but not retrieval of a two-way active avoidance response. PLoS ONE 8, e65684 (2013).
    • (2013) PLoS ONE , vol.8
    • Ilango, A.1    Shumake, J.2    Wetzel, W.3    Scheich, H.4    Ohl, F.W.5
  • 40
    • 80055055434 scopus 로고    scopus 로고
    • Electrical stimulation of the primate lateral habenula suppresses saccadic eye movement through a learning mechanism
    • Matsumoto, M. & Hikosaka, O. Electrical stimulation of the primate lateral habenula suppresses saccadic eye movement through a learning mechanism. PLoS ONE 6, e26701 (2011).
    • (2011) PLoS ONE , vol.6
    • Matsumoto, M.1    Hikosaka, O.2
  • 41
    • 84864456653 scopus 로고    scopus 로고
    • Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance
    • Stamatakis, A.M. & Stuber, G.D. Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance. Nat. Neurosci. 15, 1105-1107 (2012).
    • (2012) Nat. Neurosci. , vol.15 , pp. 1105-1107
    • Stamatakis, A.M.1    Stuber, G.D.2
  • 42
    • 84906044090 scopus 로고    scopus 로고
    • Pedunculopontine tegmental nucleus neurons provide reward, sensorimotor, and alerting signals to midbrain dopamine neurons
    • published online, doi:10.1016/j.neuroscience.2014.07.002 21 July
    • Hong, S. & Hikosaka, O. Pedunculopontine tegmental nucleus neurons provide reward, sensorimotor, and alerting signals to midbrain dopamine neurons. Neuroscience published online, doi:10.1016/j.neuroscience.2014.07.002 (21 July 2014).
    • (2014) Neuroscience
    • Hong, S.1    Hikosaka, O.2
  • 43
    • 68349115012 scopus 로고    scopus 로고
    • Midbrain dopamine neurons signal preference for advance information about upcoming rewards
    • Bromberg-Martin, E.S. & Hikosaka, O. Midbrain dopamine neurons signal preference for advance information about upcoming rewards. Neuron 63, 119-126 (2009).
    • (2009) Neuron , vol.63 , pp. 119-126
    • Bromberg-Martin, E.S.1    Hikosaka, O.2
  • 44
    • 80052211211 scopus 로고    scopus 로고
    • Lateral habenula neurons signal errors in the prediction of reward information
    • Bromberg-Martin, E.S. & Hikosaka, O. Lateral habenula neurons signal errors in the prediction of reward information. Nat. Neurosci. 14, 1209-1216 (2011).
    • (2011) Nat. Neurosci. , vol.14 , pp. 1209-1216
    • Bromberg-Martin, E.S.1    Hikosaka, O.2
  • 45
    • 84893747641 scopus 로고    scopus 로고
    • What's better for me? Fundamental role for lateral habenula in promoting subjective decision biases
    • Stopper, C.M. & Floresco, S.B. What's better for me? Fundamental role for lateral habenula in promoting subjective decision biases. Nat. Neurosci. 17, 33-35 (2014).
    • (2014) Nat. Neurosci. , vol.17 , pp. 33-35
    • Stopper, C.M.1    Floresco, S.B.2
  • 46
    • 34247637934 scopus 로고    scopus 로고
    • A conductor hidden in the orchestra? Role of the habenular complex in monoamine transmission and cognition
    • Lecourtier, L. & Kelly, P.H. A conductor hidden in the orchestra? Role of the habenular complex in monoamine transmission and cognition. Neurosci. Biobehav. Rev. 31, 658-672 (2007).
    • (2007) Neurosci. Biobehav. Rev. , vol.31 , pp. 658-672
    • Lecourtier, L.1    Kelly, P.H.2
  • 47
    • 0017363657 scopus 로고
    • Afferent connections of the habenular nuclei in the rat. A horseradish peroxidase study, with a note on the fiber-of-passage problem
    • Herkenham, M. & Nauta, W.J. Afferent connections of the habenular nuclei in the rat. A horseradish peroxidase study, with a note on the fiber-of-passage problem. J. Comp. Neurol. 173, 123-146 (1977).
    • (1977) J. Comp. Neurol. , vol.173 , pp. 123-146
    • Herkenham, M.1    Nauta, W.J.2
  • 48
    • 84856710306 scopus 로고    scopus 로고
    • Differential projections from the lateral habenula to the rostromedial tegmental nucleus and ventral tegmental area in the rat
    • Gonçalves, L., Sego, C. & Metzger, M. Differential projections from the lateral habenula to the rostromedial tegmental nucleus and ventral tegmental area in the rat. J. Comp. Neurol. 520, 1278-1300 (2012).
    • (2012) J. Comp. Neurol. , vol.520 , pp. 1278-1300
    • Gonçalves, L.1    Sego, C.2    Metzger, M.3
  • 49
    • 64049112053 scopus 로고    scopus 로고
    • Topographic commissural and descending projections of the habenula in the rat
    • Kim, U. Topographic commissural and descending projections of the habenula in the rat. J. Comp. Neurol. 513, 173-187 (2009).
    • (2009) J. Comp. Neurol. , vol.513 , pp. 173-187
    • Kim, U.1
  • 50
    • 0020461179 scopus 로고
    • Involvement of lateral habenula-dorsal raphe neurons in the differential regulation of striatal and nigral serotonergic transmission cats
    • Reisine, T.D., Soubrie, P., Artaud, F. & Glowinski, J. Involvement of lateral habenula-dorsal raphe neurons in the differential regulation of striatal and nigral serotonergic transmission cats. J. Neurosci. 2, 1062-1071 (1982).
    • (1982) J. Neurosci. , vol.2 , pp. 1062-1071
    • Reisine, T.D.1    Soubrie, P.2    Artaud, F.3    Glowinski, J.4
  • 51
    • 0024333177 scopus 로고
    • Regulation of striatal serotonin release by the lateral habenula-dorsal raphe pathway in the rat as demonstrated by in vivo microdialysis: Role of excitatory amino acids and GABA
    • Kalén, P., Strecker, R.E., Rosengren, E. & Bjorklund, A. Regulation of striatal serotonin release by the lateral habenula-dorsal raphe pathway in the rat as demonstrated by in vivo microdialysis: role of excitatory amino acids and GABA. Brain Res. 492, 187-202 (1989).
    • (1989) Brain Res. , vol.492 , pp. 187-202
    • Kalén, P.1    Strecker, R.E.2    Rosengren, E.3    Bjorklund, A.4
  • 52
    • 0035955499 scopus 로고    scopus 로고
    • The role of the habenular complex in the elevation of dorsal raphe nucleus serotonin and the changes in the behavioral responses produced by uncontrollable stress
    • Amat, J. et al. The role of the habenular complex in the elevation of dorsal raphe nucleus serotonin and the changes in the behavioral responses produced by uncontrollable stress. Brain Res. 917, 118-126 (2001).
    • (2001) Brain Res. , vol.917 , pp. 118-126
    • Amat, J.1
  • 53
    • 38749114701 scopus 로고    scopus 로고
    • Lateral habenula lesions improve the behavioral response in depressed rats via increasing the serotonin level in dorsal raphe nucleus
    • Yang, L.M., Hu, B., Xia, Y.H., Zhang, B.L. & Zhao, H. Lateral habenula lesions improve the behavioral response in depressed rats via increasing the serotonin level in dorsal raphe nucleus. Behav. Brain Res. 188, 84-90 (2008).
    • (2008) Behav. Brain Res. , vol.188 , pp. 84-90
    • Yang, L.M.1    Hu, B.2    Xia, Y.H.3    Zhang, B.L.4    Zhao, H.5
  • 54
    • 77953915232 scopus 로고    scopus 로고
    • The lateral habenula regulates defensive behaviors through changes in 5-HT-mediated neurotransmission in the dorsal periaqueductal gray matter
    • Pobbe, R.L. & Zangrossi, H. Jr. The lateral habenula regulates defensive behaviors through changes in 5-HT-mediated neurotransmission in the dorsal periaqueductal gray matter. Neurosci. Lett. 479, 87-91 (2010).
    • (2010) Neurosci. Lett. , vol.479 , pp. 87-91
    • Pobbe, R.L.1    Zangrossi Jr., H.2
  • 55
    • 0033178606 scopus 로고    scopus 로고
    • Covariation of activity in habenula and dorsal raphe nuclei following tryptophan depletion
    • Morris, J.S., Smith, K.A., Cowen, P.J., Friston, K.J. & Dolan, R.J. Covariation of activity in habenula and dorsal raphe nuclei following tryptophan depletion. Neuroimage 10, 163-172 (1999).
    • (1999) Neuroimage , vol.10 , pp. 163-172
    • Morris, J.S.1    Smith, K.A.2    Cowen, P.J.3    Friston, K.J.4    Dolan, R.J.5
  • 56
    • 45549109997 scopus 로고    scopus 로고
    • Reward-dependent modulation of neuronal activity in the primate dorsal raphe nucleus
    • Nakamura, K., Matsumoto, M. & Hikosaka, O. Reward-dependent modulation of neuronal activity in the primate dorsal raphe nucleus. J. Neurosci. 28, 5331-5343 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 5331-5343
    • Nakamura, K.1    Matsumoto, M.2    Hikosaka, O.3
  • 57
    • 77951788447 scopus 로고    scopus 로고
    • Coding of task reward value in the dorsal raphe nucleus
    • Bromberg-Martin, E.S., Hikosaka, O. & Nakamura, K. Coding of task reward value in the dorsal raphe nucleus. J. Neurosci. 30, 6262-6272 (2010).
    • (2010) J. Neurosci. , vol.30 , pp. 6262-6272
    • Bromberg-Martin, E.S.1    Hikosaka, O.2    Nakamura, K.3
  • 58
    • 0037415808 scopus 로고    scopus 로고
    • Morphologic and cytochemical criteria for the identification and delineation of individual subnuclei within the lateral habenular complex of the rat
    • Geisler, S., Andres, K.H. & Veh, R.W. Morphologic and cytochemical criteria for the identification and delineation of individual subnuclei within the lateral habenular complex of the rat. J. Comp. Neurol. 458, 78-97 (2003).
    • (2003) J. Comp. Neurol. , vol.458 , pp. 78-97
    • Geisler, S.1    Andres, K.H.2    Veh, R.W.3
  • 60
    • 0019496785 scopus 로고
    • The origin of forebrain afferents to the habenula in rat, cat and monkey
    • Parent, A., Gravel, S. & Boucher, R. The origin of forebrain afferents to the habenula in rat, cat and monkey. Brain Res. Bull. 6, 23-38 (1981).
    • (1981) Brain Res. Bull. , vol.6 , pp. 23-38
    • Parent, A.1    Gravel, S.2    Boucher, R.3
  • 61
    • 0035888183 scopus 로고    scopus 로고
    • Two types of projection neurons in the internal pallidum of primates: Single-axon tracing and three-dimensional reconstruction
    • Parent, M., Levesque, M. & Parent, A. Two types of projection neurons in the internal pallidum of primates: single-axon tracing and three-dimensional reconstruction. J. Comp. Neurol. 439, 162-175 (2001).
    • (2001) J. Comp. Neurol. , vol.439 , pp. 162-175
    • Parent, M.1    Levesque, M.2    Parent, A.3
  • 62
    • 0027474546 scopus 로고
    • The organization of the descending ventral pallidal projections in the monkey
    • Haber, S.N., Lynd-Balta, E. & Mitchell, S.J. The organization of the descending ventral pallidal projections in the monkey. J. Comp. Neurol. 329, 111-128 (1993).
    • (1993) J. Comp. Neurol. , vol.329 , pp. 111-128
    • Haber, S.N.1    Lynd-Balta, E.2    Mitchell, S.J.3
  • 63
    • 84883196504 scopus 로고    scopus 로고
    • Axonal branching patterns of ventral pallidal neurons in the rat
    • Tripathi, A., Prensa, L. & Mengual, E. Axonal branching patterns of ventral pallidal neurons in the rat. Brain Struct. Funct. 218, 1133-1157 (2013).
    • (2013) Brain Struct. Funct. , vol.218 , pp. 1133-1157
    • Tripathi, A.1    Prensa, L.2    Mengual, E.3
  • 64
    • 56349146098 scopus 로고    scopus 로고
    • The globus pallidus sends reward-related signals to the lateral habenula
    • Hong, S. & Hikosaka, O. The globus pallidus sends reward-related signals to the lateral habenula. Neuron 60, 720-729 (2008).
    • (2008) Neuron , vol.60 , pp. 720-729
    • Hong, S.1    Hikosaka, O.2
  • 65
    • 84869777921 scopus 로고    scopus 로고
    • The primate ventral pallidum encodes expected reward value and regulates motor action
    • Tachibana, Y. & Hikosaka, O. The primate ventral pallidum encodes expected reward value and regulates motor action. Neuron 76, 826-837 (2012).
    • (2012) Neuron , vol.76 , pp. 826-837
    • Tachibana, Y.1    Hikosaka, O.2
  • 66
    • 33847634405 scopus 로고    scopus 로고
    • The debate over dopamine's role in reward: The case for incentive salience
    • Berridge, K.C. The debate over dopamine's role in reward: the case for incentive salience. Psychopharmacology (Berl.) 191, 391-431 (2007).
    • (2007) Psychopharmacology (Berl.) , vol.191 , pp. 391-431
    • Berridge, K.C.1
  • 67
    • 84860163389 scopus 로고    scopus 로고
    • Serotonin selectively modulates reward value in human decision-making
    • Seymour, B., Daw, N.D., Roiser, J.P., Dayan, P. & Dolan, R. Serotonin selectively modulates reward value in human decision-making. J. Neurosci. 32, 5833-5842 (2012).
    • (2012) J. Neurosci. , vol.32 , pp. 5833-5842
    • Seymour, B.1    Daw, N.D.2    Roiser, J.P.3    Dayan, P.4    Dolan, R.5
  • 68
    • 0034076609 scopus 로고    scopus 로고
    • Emotion circuits in the brain
    • LeDoux, J.E. Emotion circuits in the brain. Annu. Rev. Neurosci. 23, 155-184 (2000).
    • (2000) Annu. Rev. Neurosci. , vol.23 , pp. 155-184
    • Ledoux, J.E.1
  • 69
    • 54049104420 scopus 로고    scopus 로고
    • Moment-to-moment tracking of state value in the amygdala
    • Belova, M.A., Paton, J.J. & Salzman, C.D. Moment-to-moment tracking of state value in the amygdala. J. Neurosci. 28, 10023-10030 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 10023-10030
    • Belova, M.A.1    Paton, J.J.2    Salzman, C.D.3
  • 71
    • 84860678825 scopus 로고    scopus 로고
    • Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin
    • Shabel, S.J., Proulx, C.D., Trias, A., Murphy, R.T. & Malinow, R. Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin. Neuron 74, 475-481 (2012).
    • (2012) Neuron , vol.74 , pp. 475-481
    • Shabel, S.J.1    Proulx, C.D.2    Trias, A.3    Murphy, R.T.4    Malinow, R.5
  • 72
    • 84888060570 scopus 로고    scopus 로고
    • A unique population of ventral tegmental area neurons inhibits the lateral habenula to promote reward
    • Stamatakis, A.M. et al. A unique population of ventral tegmental area neurons inhibits the lateral habenula to promote reward. Neuron 80, 1039-1053 (2013).
    • (2013) Neuron , vol.80 , pp. 1039-1053
    • Stamatakis, A.M.1
  • 73
    • 84858626050 scopus 로고    scopus 로고
    • Activation of VTA GABA neurons disrupts reward consumption
    • van Zessen, R., Phillips, J.L., Budygin, E.A. & Stuber, G.D. Activation of VTA GABA neurons disrupts reward consumption. Neuron 73, 1184-1194 (2012).
    • (2012) Neuron , vol.73 , pp. 1184-1194
    • Van Zessen, R.1    Phillips, J.L.2    Budygin, E.A.3    Stuber, G.D.4
  • 74
    • 1842559960 scopus 로고    scopus 로고
    • Prolonged expression of c-Fos protein in the lateral habenular nucleus of the Japanese monkey (Macaca fuscata) after eye enucleation
    • Kazi, J.A., Mori, S., Kuchiiwa, S. & Nakagawa, S. Prolonged expression of c-Fos protein in the lateral habenular nucleus of the Japanese monkey (Macaca fuscata) after eye enucleation. Neurosignals 13, 130-133 (2004).
    • (2004) Neurosignals , vol.13 , pp. 130-133
    • Kazi, J.A.1    Mori, S.2    Kuchiiwa, S.3    Nakagawa, S.4
  • 75
    • 77955270040 scopus 로고    scopus 로고
    • Brief pup exposure induces Fos expression in the lateral habenula and serotonergic caudal dorsal raphe nucleus of paternally experienced male California mice (Peromyscus californicus)
    • de Jong, T.R., Measor, K.R., Chauke, M., Harris, B.N. & Saltzman, W. Brief pup exposure induces Fos expression in the lateral habenula and serotonergic caudal dorsal raphe nucleus of paternally experienced male California mice (Peromyscus californicus). Neuroscience 169, 1094-1104 (2010).
    • (2010) Neuroscience , vol.169 , pp. 1094-1104
    • De Jong, T.R.1    Measor, K.R.2    Chauke, M.3    Harris, B.N.4    Saltzman, W.5
  • 76
    • 0037435977 scopus 로고    scopus 로고
    • Opposite metabolic changes in the habenula and ventral tegmental area of a genetic model of helpless behavior
    • Shumake, J., Edwards, E. & Gonzalez-Lima, F. Opposite metabolic changes in the habenula and ventral tegmental area of a genetic model of helpless behavior. Brain Res. 963, 274-281 (2003).
    • (2003) Brain Res. , vol.963 , pp. 274-281
    • Shumake, J.1    Edwards, E.2    Gonzalez-Lima, F.3
  • 77
    • 0035955499 scopus 로고    scopus 로고
    • The role of the habenular complex in the elevation of dorsal raphe nucleus serotonin and the changes in the behavioral responses produced by uncontrollable stress
    • Amat, J. et al. The role of the habenular complex in the elevation of dorsal raphe nucleus serotonin and the changes in the behavioral responses produced by uncontrollable stress. Brain Res. 917, 118-126 (2001).
    • (2001) Brain Res. , vol.917 , pp. 118-126
    • Amat, J.1
  • 78
    • 79952129505 scopus 로고    scopus 로고
    • Synaptic potentiation onto habenula neurons in the learned helplessness model of depression
    • Li, B. et al. Synaptic potentiation onto habenula neurons in the learned helplessness model of depression. Nature 470, 535-539 (2011).
    • (2011) Nature , vol.470 , pp. 535-539
    • Li, B.1
  • 79
    • 0034652088 scopus 로고    scopus 로고
    • Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction
    • Mizoguchi, K. et al. Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction. J. Neurosci. 20, 1568-1574 (2000).
    • (2000) J. Neurosci. , vol.20 , pp. 1568-1574
    • Mizoguchi, K.1
  • 80
    • 84883122151 scopus 로고    scopus 로고
    • CaMKII in lateral habenula mediates core symptoms of depression
    • Li, K. et al. CaMKII in lateral habenula mediates core symptoms of depression. Science 341, 1016-1020 (2013).
    • (2013) Science , vol.341 , pp. 1016-1020
    • Li, K.1
  • 81
    • 0034844817 scopus 로고    scopus 로고
    • Asymmetry in the epithalamus of vertebrates
    • Concha, M.L. & Wilson, S.W. Asymmetry in the epithalamus of vertebrates. J. Anat. 199, 63-84 (2001).
    • (2001) J. Anat. , vol.199 , pp. 63-84
    • Concha, M.L.1    Wilson, S.W.2
  • 82
    • 65649135829 scopus 로고    scopus 로고
    • Zebrafish and medaka: Model organisms for a comparative developmental approach of brain asymmetry
    • Signore, I.A. et al. Zebrafish and medaka: model organisms for a comparative developmental approach of brain asymmetry. Philos. Trans. R. Soc. Lond. B Biol. Sci. 364, 991-1003 (2009).
    • (2009) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.364 , pp. 991-1003
    • Signore, I.A.1
  • 83
    • 0023279613 scopus 로고
    • Topography of cholinergic and substance P pathways in the habenulo-interpeduncular system of the rat. An immunocytochemical and microchemical approach
    • Contestabile, A. et al. Topography of cholinergic and substance P pathways in the habenulo-interpeduncular system of the rat. An immunocytochemical and microchemical approach. Neuroscience 21, 253-270 (1987).
    • (1987) Neuroscience , vol.21 , pp. 253-270
    • Contestabile, A.1
  • 84
    • 67349241685 scopus 로고    scopus 로고
    • Neurochemical phenotypes of the afferent and efferent projections of the mouse medial habenula
    • Qin, C. & Luo, M. Neurochemical phenotypes of the afferent and efferent projections of the mouse medial habenula. Neuroscience 161, 827-837 (2009).
    • (2009) Neuroscience , vol.161 , pp. 827-837
    • Qin, C.1    Luo, M.2
  • 85
    • 63849115116 scopus 로고    scopus 로고
    • Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice
    • Salas, R., Sturm, R., Boulter, J. & De Biasi, M. Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice. J. Neurosci. 29, 3014-3018 (2009).
    • (2009) J. Neurosci. , vol.29 , pp. 3014-3018
    • Salas, R.1    Sturm, R.2    Boulter, J.3    De Biasi, M.4
  • 86
    • 79953246461 scopus 로고    scopus 로고
    • Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake
    • Fowler, C.D., Lu, Q., Johnson, P.M., Marks, M.J. & Kenny, P.J. Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake. Nature 471, 597-601 (2011).
    • (2011) Nature , vol.471 , pp. 597-601
    • Fowler, C.D.1    Lu, Q.2    Johnson, P.M.3    Marks, M.J.4    Kenny, P.J.5
  • 87
    • 79955658475 scopus 로고    scopus 로고
    • Aversion to nicotine is regulated by the balanced activity of beta4 and alpha5 nicotinic receptor subunits in the medial habenula
    • Frahm, S. et al. Aversion to nicotine is regulated by the balanced activity of beta4 and alpha5 nicotinic receptor subunits in the medial habenula. Neuron 70, 522-535 (2011).
    • (2011) Neuron , vol.70 , pp. 522-535
    • Frahm, S.1
  • 88
    • 77952423760 scopus 로고    scopus 로고
    • Evidence for structural abnormalities of the human habenular complex in affective disorders but not in schizophrenia
    • Ranft, K. et al. Evidence for structural abnormalities of the human habenular complex in affective disorders but not in schizophrenia. Psychol. Med. 40, 557-567 (2010).
    • (2010) Psychol. Med. , vol.40 , pp. 557-567
    • Ranft, K.1
  • 89
    • 84874159122 scopus 로고    scopus 로고
    • Genetic dissection of medial habenula-interpeduncular nucleus pathway function in mice
    • Kobayashi, Y. et al. Genetic dissection of medial habenula- interpeduncular nucleus pathway function in mice. Front. Behav. Neurosci. 7, 17 (2013).
    • (2013) Front. Behav. Neurosci. , vol.7 , pp. 17
    • Kobayashi, Y.1
  • 90
    • 78049318443 scopus 로고    scopus 로고
    • The habenula is crucial for experience-dependent modification of fear responses in zebrafish
    • Agetsuma, M. et al. The habenula is crucial for experience-dependent modification of fear responses in zebrafish. Nat. Neurosci. 13, 1354-1356 (2010).
    • (2010) Nat. Neurosci. , vol.13 , pp. 1354-1356
    • Agetsuma, M.1
  • 91
    • 84862023229 scopus 로고    scopus 로고
    • 34 nicotinic acetylcholine receptors in the medial habenula modulate the mesolimbic dopaminergic response to acute nicotine in vivo
    • McCallum, S.E., Cowe, M.A., Lewis, S.W. & Glick, S.D. 34 nicotinic acetylcholine receptors in the medial habenula modulate the mesolimbic dopaminergic response to acute nicotine in vivo. Neuropharmacology 63, 434-440 (2012).
    • (2012) Neuropharmacology , vol.63 , pp. 434-440
    • McCallum, S.E.1    Cowe, M.A.2    Lewis, S.W.3    Glick, S.D.4
  • 92
    • 84887376256 scopus 로고    scopus 로고
    • Medial habenula output circuit mediated by alpha5 nicotinic receptor-expressing GABAergic neurons in the interpeduncular nucleus
    • Hsu, Y.W. et al. Medial habenula output circuit mediated by alpha5 nicotinic receptor-expressing GABAergic neurons in the interpeduncular nucleus. J. Neurosci. 33, 18022-18035 (2013).
    • (2013) J. Neurosci. , vol.33 , pp. 18022-18035
    • Hsu, Y.W.1
  • 93
    • 45549096896 scopus 로고    scopus 로고
    • Interleukin-18 and stress
    • Sugama, S. & Conti, B. Interleukin-18 and stress. Brain Res. Rev. 58, 85-95 (2008).
    • (2008) Brain Res. Rev. , vol.58 , pp. 85-95
    • Sugama, S.1    Conti, B.2
  • 94
    • 84888337523 scopus 로고    scopus 로고
    • Interactions between the lateral habenula and the hippocampus: Implication for spatial memory processes
    • Goutagny, R. et al. Interactions between the lateral habenula and the hippocampus: implication for spatial memory processes. Neuropsychopharmacology 38, 2418-2426 (2013).
    • (2013) Neuropsychopharmacology , vol.38 , pp. 2418-2426
    • Goutagny, R.1
  • 95
    • 84877765324 scopus 로고    scopus 로고
    • The synchronous activity of lateral habenular neurons is essential for regulating hippocampal theta oscillation
    • Aizawa, H. et al. The synchronous activity of lateral habenular neurons is essential for regulating hippocampal theta oscillation. J. Neurosci. 33, 8909-8921 (2013).
    • (2013) J. Neurosci. , vol.33 , pp. 8909-8921
    • Aizawa, H.1
  • 96
    • 84879839639 scopus 로고    scopus 로고
    • DREADDing the lateral habenula: A review of methodological approaches for studying lateral habenula function
    • Nair, S.G., Strand, N.S. & Neumaier, J.F. DREADDing the lateral habenula: a review of methodological approaches for studying lateral habenula function. Brain Res. 1511, 93-101 (2013).
    • (2013) Brain Res. , vol.1511 , pp. 93-101
    • Nair, S.G.1    Strand, N.S.2    Neumaier, J.F.3
  • 97
    • 84887008084 scopus 로고    scopus 로고
    • GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits
    • Gerfen, C.R., Paletzki, R. & Heintz, N. GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits. Neuron 80, 1368-1383 (2013).
    • (2013) Neuron , vol.80 , pp. 1368-1383
    • Gerfen, C.R.1    Paletzki, R.2    Heintz, N.3
  • 98
    • 34548651693 scopus 로고    scopus 로고
    • Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs
    • Gong, S. et al. Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. J. Neurosci. 27, 9817-9823 (2007).
    • (2007) J. Neurosci. , vol.27 , pp. 9817-9823
    • Gong, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.