Transient receptor potential Vanilloid 1 activation by dietary capsaicin promotes urinary sodium excretion by inhibiting epithelial sodium channel α Subunit-Mediated sodium reabsorption

Hypertension

Volumn 64, Issue 2, 2014, Pages 397-404

  Li, Li ^a   Wang, Fei ^a   Wei, Xing ^a   Liang, Yi ^a   Cui, Yuanting ^a   Gao, Feng ^a   Zhong, Jian ^a   Pu, Yunfei ^a   Zhao, Yu ^a   Yan, Zhencheng ^a   Arendshorst, William J ^b   Nilius, Bernd ^c   Chen, Jing ^a   Liu, Daoyan ^a   Zhu, Zhiming ^a  

^a Chongqing Institute of Cardiology   (China)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c LABORATORY OF MOLECULAR AND CELLULAR SIGNALING   (Belgium)

Author keywords

capsaicin; ENaC alpha; hypertension; kidney collecting duct; sodium diet; transient receptor potential cation channel V1

Indexed keywords

CAPSAICIN; EPITHELIAL SODIUM CHANNEL; PROTEIN KINASE WNK1; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SODIUM; VANILLOID RECEPTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; HYPERTENSION; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SODIUM ABSORPTION; SODIUM URINE LEVEL; WILD TYPE;

CAPSAICIN ENAC ALPHA; HYPERTENSION KIDNEY COLLECTING DUCT SODIUM DIET TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL V1;

ANIMALS; BLOOD PRESSURE; CAPSAICIN; EPITHELIAL SODIUM CHANNELS; HYPERTENSION; MICE; MICE, KNOCKOUT; SODIUM; TRPV CATION CHANNELS;

EID: 84904505279     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.114.03105     Document Type: Article

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