RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome

Nature Communications

Volumn 8, Issue , 2017, Pages

  Zhang, Yingying ^a   Su, Sheng Sean ^a   Zhao, Shubo ^a   Yang, Zhentao ^a   Zhong, Chuan Qi ^a   Chen, Xin ^a   Cai, Qixu ^a   Yang, Zhang Hua ^a   Huang, Deli ^a   Wu, Rui ^a   Han, Jiahuai ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; PHOSPHOTRANSFERASE; REACTIVE OXYGEN METABOLITE; RECEPTOR INTERACTING PROTEIN 1; RECEPTOR INTERACTING PROTEIN 3; SERINE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK1 PROTEIN, HUMAN; RIPK1 PROTEIN, MOUSE; RIPK3 PROTEIN, HUMAN; RIPK3 PROTEIN, MOUSE;

AMINO ACID; CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; MITOCHONDRION; PATHOLOGY; PROTEIN; REACTIVE OXYGEN SPECIES;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CELLS BY BODY ANATOMY; EMBRYO; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL RESPIRATION; MOUSE; NECROPTOSIS; NECROSOME; NONHUMAN; OXYGEN CONSUMPTION; POSITIVE FEEDBACK; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; ANIMAL; APOPTOSIS; GENETICS; METABOLISM; MITOCHONDRION; NECROSIS; NIH 3T3 CELL LINE; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PRIMARY CELL CULTURE; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CYSTEINE; HUMANS; MICE; MITOCHONDRIA; NECROSIS; NIH 3T3 CELLS; PHOSPHORYLATION; PRIMARY CELL CULTURE; REACTIVE OXYGEN SPECIES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SERINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85012016511     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms14329     Document Type: Article

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