NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis

Cancer Cell

Volumn 28, Issue 5, 2015, Pages 582-598

  Kondylis, Vangelis ^a   Polykratis, Apostolos ^a   Ehlken, Hanno ^a,g   Ochoa Callejero, Laura ^a,h   Straub, Beate Katharina ^b   Krishna Subramanian, Santosh ^a   Van, Trieu My ^a   Curth, Harald Morten ^a   Heise, Nicole ^c   Weih, Falk ^d   Klein, Ulf ^c,e   Schirmacher, Peter ^b   Kelliher, Michelle ^f   Pasparakis, Manolis ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d FRITZ LIPMANN INSTITUTE   (Germany)

^e NewYork Presbyterian Hospital   (United States)

^f UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^g UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^h CENTER FOR BIOMEDICAL RESEARCH OF LA RIOJA CIBIR   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE; RECEPTOR INTERACTING PROTEIN KINASE 1; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR RELB; UNCLASSIFIED DRUG; I KAPPA B KINASE; IKBKB PROTEIN, MOUSE; NEMO PROTEIN, MOUSE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK1 PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; LIVER PARENCHYMA; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL CULTURE; FATTY LIVER; GENE EXPRESSION; GENETICS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LIVER; LIVER TUMOR; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELLS, CULTURED; FATTY LIVER; GENE EXPRESSION; HEPATOCYTES; I-KAPPA B KINASE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER; LIVER NEOPLASMS; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84946544180     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2015.10.001     Document Type: Article

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