Cloning, expression, and characterization of Mycobacterium tuberculosis dihydrofolate reductase

FEMS Microbiology Letters

Volumn 232, Issue 1, 2004, Pages 101-105

  White, E Lucile ^a   Ross, Larry J ^a   Cunningham, Amanda ^a   Escuyer, Vincent ^a  

^a SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

Dihydrofolate reductase; Enzyme characterization; Mycobacterium tuberculosis

Indexed keywords

BACTERIAL ENZYME; DIHYDROFOLATE REDUCTASE; GENOMIC DNA; GUANIDINE; METHOTREXATE; MONOMER; POTASSIUM CHLORIDE; TRIMETHOPRIM;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME SPECIFICITY; GEL FILTRATION; GEL FILTRATION CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR CLONING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; STEADY STATE;

AMINO ACID SEQUENCE; CHROMATOGRAPHY, LIQUID; CLONING, MOLECULAR; ENZYME INHIBITORS; ENZYME STABILITY; ESCHERICHIA COLI; HYDROGEN-ION CONCENTRATION; METHOTREXATE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; MYCOBACTERIUM TUBERCULOSIS; POTASSIUM CHLORIDE; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; TETRAHYDROFOLATE DEHYDROGENASE; TRIMETHOPRIM;

ESCHERICHIA COLI; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 1542381036     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(04)00038-2     Document Type: Article

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