메뉴 건너뛰기




Volumn 36, Issue 1, 2017, Pages

HERV-K activation is strictly required to sustain CD133+ melanoma cells with stemness features

Author keywords

Cancer stem cell; CD133; HERV K; Melanoma; Microenvironment; Retroelements

Indexed keywords

CD133 ANTIGEN; EFAVIRENZ; NEVIRAPINE; PROM1 PROTEIN, HUMAN;

EID: 85010716519     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/s13046-016-0485-x     Document Type: Article
Times cited : (54)

References (59)
  • 1
    • 74949090309 scopus 로고    scopus 로고
    • The therapeutic promise of the cancer stem cell concept
    • 1:CAS:528:DC%2BC3cXislWgtw%3D%3D 20051635 2798700 PubMed. Google Scholar
    • Frank NY, Schatton T, Frank MH. The therapeutic promise of the cancer stem cell concept. J Clin Invest. 2010;120:41-50. PubMed. Google Scholar.
    • (2010) J Clin Invest , vol.120 , pp. 41-50
    • Frank, N.Y.1    Schatton, T.2    Frank, M.H.3
  • 2
    • 84903768676 scopus 로고    scopus 로고
    • Tackling the cancer stem cells-what challenges do they pose?
    • 1:CAS:528:DC%2BC2cXhtVOisbzI 24981363 4234172 PubMed. Google Scholar
    • Pattabiraman DR, Weinberg RA. Tackling the cancer stem cells-what challenges do they pose? Nat Rev Drug Discov. 2014;13:497-512. PubMed. Google Scholar.
    • (2014) Nat Rev Drug Discov , vol.13 , pp. 497-512
    • Pattabiraman, D.R.1    Weinberg, R.A.2
  • 3
    • 84882914264 scopus 로고    scopus 로고
    • Testing the cancer stem cell hypothesis in melanoma: The clinics will tell
    • 1:CAS:528:DC%2BC38Xhs1CjsL%2FJ 23073475 PubMed. Google Scholar
    • Shakhova O, Sommer L. Testing the cancer stem cell hypothesis in melanoma: the clinics will tell. Cancer Lett. 2013;338:74-81. PubMed. Google Scholar.
    • (2013) Cancer Lett , vol.338 , pp. 74-81
    • Shakhova, O.1    Sommer, L.2
  • 4
    • 84883219941 scopus 로고    scopus 로고
    • Functional features of cancer stem cells in melanoma cell lines
    • 1:CAS:528:DC%2BC3sXhsVWhtrnM 23915418 3765139 PubMed. Google Scholar
    • Zimmerer RM, Korn P, Demougin P, Kampmann A, Kokemüller H, Eckardt AM, et al. Functional features of cancer stem cells in melanoma cell lines. Cancer Cell Int. 2013;13:78. PubMed. Google Scholar.
    • (2013) Cancer Cell Int , vol.13 , pp. 78
    • Zimmerer, R.M.1    Korn, P.2    Demougin, P.3    Kampmann, A.4    Kokemüller, H.5    Eckardt, A.M.6
  • 5
    • 84856216836 scopus 로고    scopus 로고
    • CD133, Stem Cells, and Cancer Stem Cells: Myth or Reality?
    • 22131911 3207123 PubMed. Google Scholar
    • Yu X, Lin Y, Yan X, Tian Q, Li L, Lin EH. CD133, Stem Cells, and Cancer Stem Cells: Myth or Reality? Curr Colorectal Cancer Rep. 2011;7:253-9. PubMed. Google Scholar.
    • (2011) Curr Colorectal Cancer Rep , vol.7 , pp. 253-259
    • Yu, X.1    Lin, Y.2    Yan, X.3    Tian, Q.4    Li, L.5    Lin, E.H.6
  • 6
    • 33847639310 scopus 로고    scopus 로고
    • Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential
    • 1:CAS:528:DC%2BD2sXisleitLg%3D 17320377 PubMed. Google Scholar
    • Monzani E, Facchetti F, Galmozzi E, Corsini E, Benetti A, Cavazzin C, et al. Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential. Eur J Cancer. 2007;43:935-46. PubMed. Google Scholar.
    • (2007) Eur J Cancer , vol.43 , pp. 935-946
    • Monzani, E.1    Facchetti, F.2    Galmozzi, E.3    Corsini, E.4    Benetti, A.5    Cavazzin, C.6
  • 7
    • 79955543814 scopus 로고    scopus 로고
    • Melanoma stem cells: Not rare, but well done
    • 21445060 PubMed. Google Scholar
    • Girouard SD, Murphy GF. Melanoma stem cells: not rare, but well done. Lab Invest. 2011;91:647-64. PubMed. Google Scholar.
    • (2011) Lab Invest , vol.91 , pp. 647-664
    • Girouard, S.D.1    Murphy, G.F.2
  • 8
    • 84867113773 scopus 로고    scopus 로고
    • CD133+ melanoma subpopulations contribute to perivascular niche morphogenesis and tumorigenicity through vasculogenic mimicry
    • 1:CAS:528:DC%2BC38XhsVOqtb%2FE 22865455 3463654 PubMed. Google Scholar
    • Lai CY, Schwartz BE, Hsu MY. CD133+ melanoma subpopulations contribute to perivascular niche morphogenesis and tumorigenicity through vasculogenic mimicry. Cancer Res. 2012;72:5111-8. PubMed. Google Scholar.
    • (2012) Cancer Res , vol.72 , pp. 5111-5118
    • Lai, C.Y.1    Schwartz, B.E.2    Hsu, M.Y.3
  • 9
    • 84879502917 scopus 로고    scopus 로고
    • The stem cell marker prominin-1/CD133 interacts with vascular endothelial growth factor and potentiates its action
    • 1:CAS:528:DC%2BC3sXktF2rt7Y%3D 23150059 PubMed. Google Scholar
    • Adini A, Adini I, Ghosh K, Benny O, Pravda E, Hu R, et al. The stem cell marker prominin-1/CD133 interacts with vascular endothelial growth factor and potentiates its action. Angiogenesis. 2013;16:405-16. PubMed. Google Scholar.
    • (2013) Angiogenesis , vol.16 , pp. 405-416
    • Adini, A.1    Adini, I.2    Ghosh, K.3    Benny, O.4    Pravda, E.5    Hu, R.6
  • 10
    • 84890860169 scopus 로고    scopus 로고
    • Identification and analysis of CD133(+) melanoma stem-like cells conferring resistance to taxol: An insight into the mechanisms of their resistance and response
    • 1:CAS:528:DC%2BC3sXhs1Wlu7nO 24080340 PubMed. Google Scholar
    • El-Khattouti A, Selimovic D, Haïkel Y, Megahed M, Gomez CR, Hassan M. Identification and analysis of CD133(+) melanoma stem-like cells conferring resistance to taxol: An insight into the mechanisms of their resistance and response. Cancer Lett. 2014;343:123-33. PubMed. Google Scholar.
    • (2014) Cancer Lett , vol.343 , pp. 123-133
    • El-Khattouti, A.1    Selimovic, D.2    Haïkel, Y.3    Megahed, M.4    Gomez, C.R.5    Hassan, M.6
  • 11
    • 58049201990 scopus 로고    scopus 로고
    • The Stem CellAssociated Antigen CD133 (Prominin1) Is a Molecular Therapeutic Target for Metastatic Melanoma
    • 1:CAS:528:DC%2BD1MXhtFSktrg%3D 18802032 2713505 PubMed. Google Scholar
    • Rappa G, Fodstad O, Lorico A. The Stem CellAssociated Antigen CD133 (Prominin1) Is a Molecular Therapeutic Target for Metastatic Melanoma. Stem Cells. 2008;26:3008-17. PubMed. Google Scholar.
    • (2008) Stem Cells , vol.26 , pp. 3008-3017
    • Rappa, G.1    Fodstad, O.2    Lorico, A.3
  • 14
    • 78049237405 scopus 로고    scopus 로고
    • Cancer stem cells versus phenotypeswitching in melanoma
    • PubMed. Google Scholar
    • Hook KS, Goding CR. Cancer stem cells versus phenotypeswitching in melanoma. Pigment Cell Melanoma Res. 2010;23:746-59. PubMed. Google Scholar.
    • (2010) Pigment Cell Melanoma Res , vol.23 , pp. 746-759
    • Hook, K.S.1    Goding, C.R.2
  • 15
    • 84881595452 scopus 로고    scopus 로고
    • 'There and back again': Revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic era
    • 23938753 3758188 PubMed. Google Scholar
    • Magiorkinis G, Belshaw R, Katzourakis A. 'There and back again': revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic era. Philos Trans R Soc Lond B Biol Sci. 2013;368:20120504. PubMed. Google Scholar.
    • (2013) Philos Trans R Soc Lond B Biol Sci , vol.368 , pp. 20120504
    • Magiorkinis, G.1    Belshaw, R.2    Katzourakis, A.3
  • 16
    • 84978884000 scopus 로고    scopus 로고
    • CTRL+ INSERT: Retrotransposons and their contribution to regulation and innovation of the transcriptome
    • 27402545 PubMed. Google Scholar
    • Göke J, Ng HH. CTRL+ INSERT: retrotransposons and their contribution to regulation and innovation of the transcriptome. EMBO Rep. 2016;17:1131-44. PubMed. Google Scholar.
    • (2016) EMBO Rep , vol.17 , pp. 1131-1144
    • Göke, J.1    Ng, H.H.2
  • 17
    • 84930205085 scopus 로고    scopus 로고
    • Retrotransposons shape species-specific embryonic stem cell gene expression
    • 26021318 4448215 PubMed. Google Scholar
    • Robbez-Masson L, Rowe HM. Retrotransposons shape species-specific embryonic stem cell gene expression. Retrovirology. 2015;12:45. PubMed. Google Scholar.
    • (2015) Retrovirology , vol.12 , pp. 45
    • Robbez-Masson, L.1    Rowe, H.M.2
  • 18
    • 7944225987 scopus 로고    scopus 로고
    • Expression analyses of human endogenous retroviruses (HERVs): Tissue-specific and developmental stage-dependent expression of HERVs
    • 1:CAS:528:DC%2BD2cXptlyktrY%3D 15533715 PubMed. Google Scholar
    • Okahara G, Matsubara S, Oda T, Sugimoto J, Jinno Y, Kanaya F. Expression analyses of human endogenous retroviruses (HERVs): tissue-specific and developmental stage-dependent expression of HERVs. Genomics. 2004;84:982-90. PubMed. Google Scholar.
    • (2004) Genomics , vol.84 , pp. 982-990
    • Okahara, G.1    Matsubara, S.2    Oda, T.3    Sugimoto, J.4    Jinno, Y.5    Kanaya, F.6
  • 19
    • 84924053786 scopus 로고    scopus 로고
    • Transcriptional Activity of Human Endogenous Retroviruses in Human Peripheral Blood Mononuclear Cells
    • 25734056 4334862 PubMed. Google Scholar
    • Balestrieri E, Pica F, Matteucci C, Zenobi R, Sorrentino R, Argaw-Denboba A, et al. Transcriptional Activity of Human Endogenous Retroviruses in Human Peripheral Blood Mononuclear Cells. Biomed Res Int. 2015;2015:164529. PubMed. Google Scholar.
    • (2015) Biomed Res Int , vol.2015 , pp. 164529
    • Balestrieri, E.1    Pica, F.2    Matteucci, C.3    Zenobi, R.4    Sorrentino, R.5    Argaw-Denboba, A.6
  • 20
    • 84869102547 scopus 로고    scopus 로고
    • HERVs expression in autism spectrum disorders
    • 1:CAS:528:DC%2BC38XhslOhsr7K 23155411 3498248 PubMed. Google Scholar
    • Balestrieri E, Arpino C, Matteucci C, Sorrentino R, Pica F, Alessandrelli R, et al. HERVs expression in autism spectrum disorders. PLoS One. 2012;7:e48831. PubMed. Google Scholar.
    • (2012) PLoS One , vol.7 , pp. e48831
    • Balestrieri, E.1    Arpino, C.2    Matteucci, C.3    Sorrentino, R.4    Pica, F.5    Alessandrelli, R.6
  • 22
    • 84881611369 scopus 로고    scopus 로고
    • Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis
    • 1:CAS:528:DC%2BC3sXht12gsb3F 23864388 4352332 PubMed. Google Scholar
    • Young GR, Stoye JP, Kassiotis G. Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis. Bioessays. 2013;35:794-803. PubMed. Google Scholar.
    • (2013) Bioessays , vol.35 , pp. 794-803
    • Young, G.R.1    Stoye, J.P.2    Kassiotis, G.3
  • 23
    • 84871714941 scopus 로고    scopus 로고
    • Human endogenous retroviruses and cancer prevention: Evidence and prospects
    • 1:CAS:528:DC%2BC3sXjtVKhs74%3D 23282240 3557136 PubMed. Google Scholar
    • Cegolon L, Salata C, Weiderpass E, Vineis P, Palù G, Mastrangelo G. Human endogenous retroviruses and cancer prevention: evidence and prospects. BMC Cancer. 2013;13:4. PubMed. Google Scholar.
    • (2013) BMC Cancer , vol.13 , pp. 4
    • Cegolon, L.1    Salata, C.2    Weiderpass, E.3    Vineis, P.4    Palù, G.5    Mastrangelo, G.6
  • 24
    • 84936847607 scopus 로고    scopus 로고
    • Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice?
    • 1:CAS:528:DC%2BC2cXpvVars7s%3D 24890612 PubMed. Google Scholar
    • Downey RF, Sullivan FJ, Wang-Johanning F, Ambs S, Giles FJ, Glynn SA. Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice? Int J Cancer. 2015;137:1249-57. PubMed. Google Scholar.
    • (2015) Int J Cancer , vol.137 , pp. 1249-1257
    • Downey, R.F.1    Sullivan, F.J.2    Wang-Johanning, F.3    Ambs, S.4    Giles, F.J.5    Glynn, S.A.6
  • 25
    • 84891095297 scopus 로고    scopus 로고
    • HERV-K(HML-2), the best preserved family of HERVs: Endogenization, expression, and implications in health and disease
    • 24066280 3778440 PubMed. Google Scholar
    • Hohn O, Hanke K, Bannert N. HERV-K(HML-2), the best preserved family of HERVs: endogenization, expression, and implications in health and disease. Front Oncol. 2013;3:246. PubMed. Google Scholar.
    • (2013) Front Oncol , vol.3 , pp. 246
    • Hohn, O.1    Hanke, K.2    Bannert, N.3
  • 26
    • 59849108105 scopus 로고    scopus 로고
    • The activation of human endogenous retrovirus K(HERV-K) is implicated in melanoma cell malignant transformation
    • 1:CAS:528:DC%2BD1MXitFSgsbw%3D 19167380 PubMed. Google Scholar
    • Serafino A, Balestrieri E, Pierimarchi P, Matteucci C, Moroni G, Oricchio E, et al. The activation of human endogenous retrovirus K(HERV-K) is implicated in melanoma cell malignant transformation. Exp Cell Res. 2009;315:849-62. PubMed. Google Scholar.
    • (2009) Exp Cell Res , vol.315 , pp. 849-862
    • Serafino, A.1    Balestrieri, E.2    Pierimarchi, P.3    Matteucci, C.4    Moroni, G.5    Oricchio, E.6
  • 27
    • 34250803852 scopus 로고    scopus 로고
    • Distinct roles for LINE-1 and HERV-K retroelements in cell proliferation, differentiation and tumor progression
    • 1:CAS:528:DC%2BD2sXmslSrtb4%3D 17237820 PubMed. Google Scholar
    • Oricchio E, Sciamanna I, Beraldi R, Tolstonog GV, Schumann GG, Spadafora C. Distinct roles for LINE-1 and HERV-K retroelements in cell proliferation, differentiation and tumor progression. Oncogene. 2007;26:4226-33. PubMed. Google Scholar.
    • (2007) Oncogene , vol.26 , pp. 4226-4233
    • Oricchio, E.1    Sciamanna, I.2    Beraldi, R.3    Tolstonog, G.V.4    Schumann, G.G.5    Spadafora, C.6
  • 28
    • 84876562952 scopus 로고    scopus 로고
    • Transcriptional profiling of human endogenous retrovirus group HERV-K (HML-2) loci in melanoma
    • 23338945 3590776 PubMed. Google Scholar
    • Schmitt K, Reichrath J, Roesch A, Meese E, Mayer J. Transcriptional profiling of human endogenous retrovirus group HERV-K (HML-2) loci in melanoma. Genome Biol Evol. 2013;5:307-28. PubMed. Google Scholar.
    • (2013) Genome Biol Evol , vol.5 , pp. 307-328
    • Schmitt, K.1    Reichrath, J.2    Roesch, A.3    Meese, E.4    Mayer, J.5
  • 29
    • 77957581360 scopus 로고    scopus 로고
    • Differential expression of human endogenous retrovirus K transcripts in primary human melanocytes and melanoma cell lines after UV irradiation
    • 1:CAS:528:DC%2BC3cXhtFaqsbvJ 20539243 PubMed. Google Scholar
    • Reiche J, Pauli G, Ellerbrok H. Differential expression of human endogenous retrovirus K transcripts in primary human melanocytes and melanoma cell lines after UV irradiation. Melanoma Res. 2010;20:435-40. PubMed. Google Scholar.
    • (2010) Melanoma Res , vol.20 , pp. 435-440
    • Reiche, J.1    Pauli, G.2    Ellerbrok, H.3
  • 30
    • 4544277620 scopus 로고    scopus 로고
    • Np9 protein of human endogenous retrovirus K interacts with ligand of numb protein X
    • 1:CAS:528:DC%2BD2cXotVems7g%3D 15367597 516385 PubMed. Google Scholar
    • Armbruester V, Sauter M, Roemer K, Best B, Hahn S, Nty A, et al. Np9 protein of human endogenous retrovirus K interacts with ligand of numb protein X. J Virol. 2004;78:10310-9. PubMed. Google Scholar.
    • (2004) J Virol , vol.78 , pp. 10310-10319
    • Armbruester, V.1    Sauter, M.2    Roemer, K.3    Best, B.4    Hahn, S.5    Nty, A.6
  • 31
    • 84886024597 scopus 로고    scopus 로고
    • Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells
    • 24156636 3819666 PubMed. Google Scholar
    • Fuchs NV, Loewer S, Daley GQ, Izsvák Z, Lower J, Lower R. Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells. Retrovirology. 2013;10:115. PubMed. Google Scholar.
    • (2013) Retrovirology , vol.10 , pp. 115
    • Fuchs, N.V.1    Loewer, S.2    Daley, G.Q.3    Izsvák, Z.4    Lower, J.5    Lower, R.6
  • 32
    • 11144332583 scopus 로고    scopus 로고
    • Protection against melanoma by vaccination with bacilleCalmette-Guérin (BCG) and/or vaccinia: An epidemiology-based hypothesis on the nature of a melanoma risk factor and its immunological control
    • 1:CAS:528:DC%2BD2MXhtVGisw%3D%3D 15617995 PubMed. Google Scholar
    • Krone B, Kölmel KF, Henz BM, Grange JM. Protection against melanoma by vaccination with bacilleCalmette-Guérin (BCG) and/or vaccinia: an epidemiology-based hypothesis on the nature of a melanoma risk factor and its immunological control. Eur J Cancer. 2005;41:104-17. PubMed. Google Scholar.
    • (2005) Eur J Cancer , vol.41 , pp. 104-117
    • Krone, B.1    Kölmel, K.F.2    Henz, B.M.3    Grange, J.M.4
  • 33
    • 16844382350 scopus 로고    scopus 로고
    • Endogenous retrovirus expression is required for murine melanoma tumor growth in vivo
    • 1:CAS:528:DC%2BD2MXjtVeqs7s%3D 15805254 PubMed. Google Scholar
    • Mangeney M, Pothlichet J, Renard M, Ducos B, Heidmann T. Endogenous retrovirus expression is required for murine melanoma tumor growth in vivo. Cancer Res. 2005;65:2588-91. PubMed. Google Scholar.
    • (2005) Cancer Res , vol.65 , pp. 2588-2591
    • Mangeney, M.1    Pothlichet, J.2    Renard, M.3    Ducos, B.4    Heidmann, T.5
  • 34
    • 85010774677 scopus 로고    scopus 로고
    • The Potential Importance of K Type Human Endogenous Retroviral Elements in Melanoma Biology
    • DOI: 10.5772/55264. Article. Google Scholar
    • Dong J, Huang G, Imtiaz R, Xu F. The Potential Importance of K Type Human Endogenous Retroviral Elements in Melanoma Biology. INTECH Open Access Publisher 2013; DOI: 10.5772/55264. Article. Google Scholar
    • (2013) INTECH Open Access Publisher
    • Dong, J.1    Huang, G.2    Imtiaz, R.3    Xu, F.4
  • 35
    • 84888047460 scopus 로고    scopus 로고
    • Human endogenous retroviral K element encodes fusogenic activity in melanoma cells
    • 23599687 3622401 PubMed. Google Scholar
    • Huang G, Li Z, Wan X, Wang Y, Dong J. Human endogenous retroviral K element encodes fusogenic activity in melanoma cells. J Carcinog. 2013;12:5. PubMed. Google Scholar.
    • (2013) J Carcinog , vol.12 , pp. 5
    • Huang, G.1    Li, Z.2    Wan, X.3    Wang, Y.4    Dong, J.5
  • 36
    • 84883214066 scopus 로고    scopus 로고
    • Targeting RAS/RAF/MEK/ERK signaling in metastatic melanoma
    • 1:CAS:528:DC%2BC3sXhtFOiu7%2FP 23893853 PubMed. Google Scholar
    • Wang AX, Qi XY. Targeting RAS/RAF/MEK/ERK signaling in metastatic melanoma. IUBMB Life. 2013;65:748-58. PubMed. Google Scholar.
    • (2013) IUBMB Life , vol.65 , pp. 748-758
    • Wang, A.X.1    Qi, X.Y.2
  • 37
    • 0027716361 scopus 로고
    • Characterization of three melanoma cell lines (TVM-A12, TVM-A197, TVM-BO) sensitivity to lysis and effect of retinoic acid
    • 1:CAS:528:DyaK2cXmtVSht74%3D Google Scholar
    • Melino G, Sinibaldi-Vallebona P, D'Altri S, Annichiarico-Petruzzelli M, Rasi G, Catani MV, et al. Characterization of three melanoma cell lines (TVM-A12, TVM-A197, TVM-BO) sensitivity to lysis and effect of retinoic acid. Clin Chem Enzymol Commun. 1993;6:105-19. Google Scholar.
    • (1993) Clin Chem Enzymol Commun , vol.6 , pp. 105-119
    • Melino, G.1    Sinibaldi-Vallebona, P.2    D'Altri, S.3    Annichiarico-Petruzzelli, M.4    Rasi, G.5    Catani, M.V.6
  • 38
    • 4644306516 scopus 로고    scopus 로고
    • A distinct "side population" of cells with high drug efflux capacity in human tumor cells
    • 1:CAS:528:DC%2BD2cXosVyltr8%3D 15381773 521140 PubMed. Google Scholar
    • Hirschmann-Jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, et al. A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci U S A. 2004;101:14228-33. PubMed. Google Scholar.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 14228-14233
    • Hirschmann-Jax, C.1    Foster, A.E.2    Wulf, G.G.3    Nuchtern, J.G.4    Jax, T.W.5    Gobel, U.6
  • 39
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • 1:CAS:528:DyaK28XisFemsLw%3D 8666936 PubMed. Google Scholar
    • Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med. 1996;183:1797-806. PubMed. Google Scholar.
    • (1996) J Exp Med , vol.183 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 40
    • 84884846749 scopus 로고    scopus 로고
    • The human melanoma side population displays molecular and functional characteristics of enriched chemoresistance and tumorigenesis
    • 1:CAS:528:DC%2BC3sXhsFyru7%2FP 24098529 3789681 PubMed. Google Scholar
    • Wouters J, Stas M, Gremeaux L, Govaere O, Maes H, Agostinis P, et al. The human melanoma side population displays molecular and functional characteristics of enriched chemoresistance and tumorigenesis. PLoS One. 2013;8:e76550. PubMed. Google Scholar.
    • (2013) PLoS One , vol.8 , pp. e76550
    • Wouters, J.1    Stas, M.2    Gremeaux, L.3    Govaere, O.4    Maes, H.5    Agostinis, P.6
  • 41
    • 20544437829 scopus 로고    scopus 로고
    • Inhibition of endogenous reverse transcriptase antagonizes human tumor growth
    • 1:CAS:528:DC%2BD2MXks1Onsr8%3D 15806170 PubMed. Google Scholar
    • Sciamanna I, Landriscina M, Pittoggi C, Quirino M, Mearelli C, Beraldi R, et al. Inhibition of endogenous reverse transcriptase antagonizes human tumor growth. Oncogene. 2005;24:3923-31. PubMed. Google Scholar.
    • (2005) Oncogene , vol.24 , pp. 3923-3931
    • Sciamanna, I.1    Landriscina, M.2    Pittoggi, C.3    Quirino, M.4    Mearelli, C.5    Beraldi, R.6
  • 42
    • 0035422746 scopus 로고    scopus 로고
    • A novel autocrine pathway of tumor escape from immune recognition: Melanoma cell lines produce a soluble protein that diminishes expression of the gene encoding the melanocyte lineage melan-A/MART-1 antigen through down-modulation of its promoter
    • 1:CAS:528:DC%2BD3MXls1Wktbw%3D 11466335 PubMed. Google Scholar
    • Kurnick JT, Ramirez-Montagut T, Boyle LA, Andrews DM, Pandolfi F, Durda PJ, et al. A novel autocrine pathway of tumor escape from immune recognition: melanoma cell lines produce a soluble protein that diminishes expression of the gene encoding the melanocyte lineage melan-A/MART-1 antigen through down-modulation of its promoter. J Immunol. 2001;167:1204-11. PubMed. Google Scholar.
    • (2001) J Immunol , vol.167 , pp. 1204-1211
    • Kurnick, J.T.1    Ramirez-Montagut, T.2    Boyle, L.A.3    Andrews, D.M.4    Pandolfi, F.5    Durda, P.J.6
  • 43
    • 67649657641 scopus 로고    scopus 로고
    • HLA and melanoma: Multiple alterations in HLA class i and II expression in human melanoma cell lines from ESTDAB cell bank
    • 1:CAS:528:DC%2BD1MXnslent7s%3D 19340423 PubMed. Google Scholar
    • Mendez R, Aptsiauri N, Del Campo A, Maleno I, Cabrera T, Ruiz-Cabello F, et al. HLA and melanoma: multiple alterations in HLA class I and II expression in human melanoma cell lines from ESTDAB cell bank. Cancer Immunol Immunother. 2009;58:1507-15. PubMed. Google Scholar.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1507-1515
    • Mendez, R.1    Aptsiauri, N.2    Del Campo, A.3    Maleno, I.4    Cabrera, T.5    Ruiz-Cabello, F.6
  • 44
    • 57149109138 scopus 로고    scopus 로고
    • ICAM-1 has a critical role in the regulation of metastatic melanoma tumor susceptibility to CTL lysis by interfering with PI3K/AKT pathway
    • 19047166 PubMed. Google Scholar
    • Hamaï A, Meslin F, Benlalam H, Jalil A, Mehrpour M, Faure F, et al. ICAM-1 has a critical role in the regulation of metastatic melanoma tumor susceptibility to CTL lysis by interfering with PI3K/AKT pathway. Cancer Res. 2008;68:9854-64. PubMed. Google Scholar.
    • (2008) Cancer Res , vol.68 , pp. 9854-9864
    • Hamaï, A.1    Meslin, F.2    Benlalam, H.3    Jalil, A.4    Mehrpour, M.5    Faure, F.6
  • 45
    • 84960539259 scopus 로고    scopus 로고
    • CD10-Equipped Melanoma Cells Acquire Highly Potent Tumorigenic Activity: A Plausible Explanation of Their Significance for a Poor Prognosis
    • 26881775 4755541 PubMed. Google Scholar
    • Oba J, Nakahara T, Hashimoto-Hachiya A, Liu M, Abe T, Hagihara A, et al. CD10-Equipped Melanoma Cells Acquire Highly Potent Tumorigenic Activity: A Plausible Explanation of Their Significance for a Poor Prognosis. PLoS One. 2016;11:e0149285. PubMed. Google Scholar.
    • (2016) PLoS One , vol.11 , pp. e0149285
    • Oba, J.1    Nakahara, T.2    Hashimoto-Hachiya, A.3    Liu, M.4    Abe, T.5    Hagihara, A.6
  • 46
    • 84939897437 scopus 로고    scopus 로고
    • Microenvironmental influences on metastasis suppressor expression and function during a metastatic cell's journey
    • 1:CAS:528:DC%2BC2cXhtVaktrzL 24938990 4275500 PubMed. Google Scholar
    • Liu W, Vivian CJ, Brinker AE, Hampton KR, Lianidou E, Welch DR. Microenvironmental influences on metastasis suppressor expression and function during a metastatic cell's journey. Cancer Microenviron. 2014;7:117-31. PubMed. Google Scholar.
    • (2014) Cancer Microenviron , vol.7 , pp. 117-131
    • Liu, W.1    Vivian, C.J.2    Brinker, A.E.3    Hampton, K.R.4    Lianidou, E.5    Welch, D.R.6
  • 47
    • 84907086036 scopus 로고    scopus 로고
    • Critical role of STAT3 in melanoma metastasis through anoikis resistance
    • 25216522 4196183 PubMed. Google Scholar
    • Fofaria NM, Srivastava SK. Critical role of STAT3 in melanoma metastasis through anoikis resistance. Oncotarget. 2014;5:7051-64. PubMed. Google Scholar.
    • (2014) Oncotarget , vol.5 , pp. 7051-7064
    • Fofaria, N.M.1    Srivastava, S.K.2
  • 48
    • 0029938821 scopus 로고    scopus 로고
    • The viruses in all of us: Characteristics and biological significance of human endogenous retrovirus sequences
    • 8643549 39218 PubMed. Google Scholar
    • Löwer R, Löwer J, Kurth R. The viruses in all of us: characteristics and biological significance of human endogenous retrovirus sequences. Proc Natl Acad Sci U S A. 1996;93:5177-84. PubMed. Google Scholar.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5177-5184
    • Löwer, R.1    Löwer, J.2    Kurth, R.3
  • 49
    • 84923622377 scopus 로고    scopus 로고
    • Phenotype switching in melanoma: Implications for progression and therapy
    • 25763355 4327420 PubMed. Google Scholar
    • Li FZ, Dhillon AS, Anderson RL, McArthur G, Ferrao PT. Phenotype switching in melanoma: implications for progression and therapy. Front Oncol. 2015;5:31. PubMed. Google Scholar.
    • (2015) Front Oncol , vol.5 , pp. 31
    • Li, F.Z.1    Dhillon, A.S.2    Anderson, R.L.3    McArthur, G.4    Ferrao, P.T.5
  • 50
    • 84906922339 scopus 로고    scopus 로고
    • Metastatic cancer stem cells: From the concept to therapeutics
    • 1:CAS:528:DC%2BC2cXhvFais7bJ 25232505 4163604 PubMed. Google Scholar
    • Liao WT, Ye YP, Deng YJ, Bian XW, Ding YQ. Metastatic cancer stem cells: from the concept to therapeutics. Am J Stem Cells. 2014;3:46-62. PubMed. Google Scholar.
    • (2014) Am J Stem Cells , vol.3 , pp. 46-62
    • Liao, W.T.1    Ye, Y.P.2    Deng, Y.J.3    Bian, X.W.4    Ding, Y.Q.5
  • 51
    • 84884232859 scopus 로고    scopus 로고
    • Pluripotency transcription factors and cancer stem cells: Small genes make a big difference
    • 23419197 3845564 PubMed. Google Scholar
    • Liu A, Yu X, Liu S. Pluripotency transcription factors and cancer stem cells: small genes make a big difference. Chin J Cancer. 2013;32:483-7. PubMed. Google Scholar.
    • (2013) Chin J Cancer , vol.32 , pp. 483-487
    • Liu, A.1    Yu, X.2    Liu, S.3
  • 53
    • 58249095085 scopus 로고    scopus 로고
    • Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells
    • 1:CAS:528:DC%2BD1MXlsFKrtQ%3D%3D 18836486 PubMed. Google Scholar
    • Baba T, Convery PA, Matsumura N, Whitaker RS, Kondoh E, Perry T, et al. Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells. Oncogene. 2009;28:209-18. PubMed. Google Scholar.
    • (2009) Oncogene , vol.28 , pp. 209-218
    • Baba, T.1    Convery, P.A.2    Matsumura, N.3    Whitaker, R.S.4    Kondoh, E.5    Perry, T.6
  • 54
    • 84959887895 scopus 로고    scopus 로고
    • Prognostic significance of stem cell marker CD133 determined by promoter methylation but not by immunohistochemical expression in malignant gliomas
    • 1:CAS:528:DC%2BC28XhtVars7s%3D 26757925 4781890 PubMed. Google Scholar
    • Wu X, Wu F, Xu D, Zhang T. Prognostic significance of stem cell marker CD133 determined by promoter methylation but not by immunohistochemical expression in malignant gliomas. J Neurooncol. 2016;127:221-32. PubMed. Google Scholar.
    • (2016) J Neurooncol , vol.127 , pp. 221-232
    • Wu, X.1    Wu, F.2    Xu, D.3    Zhang, T.4
  • 55
    • 77954661906 scopus 로고    scopus 로고
    • DNA hypomethylation in cancer cells
    • 1:CAS:528:DC%2BD1MXhs1WhtLrI 20495664 2873040 PubMed. Google Scholar
    • Ehrlich M. DNA hypomethylation in cancer cells. Epigenomics. 2009;1:239-59. PubMed. Google Scholar.
    • (2009) Epigenomics , vol.1 , pp. 239-259
    • Ehrlich, M.1
  • 56
    • 77950633126 scopus 로고    scopus 로고
    • Regulation of human endogenous retrovirusK expression in melanomas by CpG methylation
    • 1:CAS:528:DC%2BC3cXjtFKhsL4%3D 20095041 PubMed. Google Scholar
    • Stengel S, Fiebig U, Kurth R, Denner J. Regulation of human endogenous retrovirusK expression in melanomas by CpG methylation. Genes Chromosomes Cancer. 2010;49:401-11. PubMed. Google Scholar.
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 401-411
    • Stengel, S.1    Fiebig, U.2    Kurth, R.3    Denner, J.4
  • 57
    • 79953691143 scopus 로고    scopus 로고
    • Retrotransposon-encoded reverse transcriptase in the genesis, progression and cellular plasticity of human cancer
    • PubMed. Google Scholar
    • Sinibaldi-Vallebona P, Matteucci C, Spadafora C. Retrotransposon-encoded reverse transcriptase in the genesis, progression and cellular plasticity of human cancer. Cancers (Basel). 2011;3:1141-57. PubMed. Google Scholar.
    • (2011) Cancers (Basel) , vol.3 , pp. 1141-1157
    • Sinibaldi-Vallebona, P.1    Matteucci, C.2    Spadafora, C.3
  • 58
    • 84907994611 scopus 로고    scopus 로고
    • Regulatory roles of LINE-1-encoded reverse transcriptase in cancer onset and progression
    • 25478632 4226666 PubMed. Google Scholar
    • Sciamanna I, Gualtieri A, Piazza PV, Spadafora C. Regulatory roles of LINE-1-encoded reverse transcriptase in cancer onset and progression. Oncotarget. 2014;5:8039-51. PubMed. Google Scholar.
    • (2014) Oncotarget , vol.5 , pp. 8039-8051
    • Sciamanna, I.1    Gualtieri, A.2    Piazza, P.V.3    Spadafora, C.4
  • 59
    • 84969523755 scopus 로고    scopus 로고
    • The Reverse Transcriptase Encoded by LINE-1 Retrotransposons in the Genesis, Progression, and Therapy of Cancer
    • 26904537 4749692 PubMed. Google Scholar
    • Sciamanna I, De Luca C, Spadafora C. The Reverse Transcriptase Encoded by LINE-1 Retrotransposons in the Genesis, Progression, and Therapy of Cancer. Front Chem. 2016;4:6. PubMed. Google Scholar.
    • (2016) Front Chem , vol.4 , pp. 6
    • Sciamanna, I.1    De Luca, C.2    Spadafora, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.