Exosomes derived from human platelet-rich plasma prevent apoptosis induced by glucocorticoid-associated endoplasmic reticulum stress in rat osteonecrosis of the femoral head via the Akt/Bad/Bcl-2 signal pathway

Theranostics

Volumn 7, Issue 3, 2017, Pages 733-750

  Tao, Shi Cong ^a   Yuan, Ting ^a   Rui, Bi Yu ^a   Zhu, Zhen Zhong ^a   Guo, Shang Chun ^a   Zhang, Chang Qing ^a  

^a SHANGHAI JIAO TONG UNIVERSITY AFFILIATED SIXTH PEOPLE S HOSPITAL   (China)

Author keywords

Apoptosis; Endoplasmic reticulum stress; Exosomes; Glucocorticoids; Osteonecrosis of the femoral head; Platelet rich plasma

Indexed keywords

CASPASE 3; DEXAMETHASONE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; METHYLPREDNISOLONE; PROTEIN BAD; PROTEIN BCL 2; PROTEIN KINASE B; GLUCOCORTICOID;

ADULT; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE DEVELOPMENT; CELL PROLIFERATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME MECHANISM; EXOSOME; FEMALE; FEMUR HEAD NECROSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; THROMBOCYTE RICH PLASMA; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; METABOLISM; OSTEOBLAST; PHYSIOLOGY; TREATMENT OUTCOME;

ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; EXOSOMES; FEMUR HEAD NECROSIS; GLUCOCORTICOIDS; MICE; OSTEOBLASTS; RATS; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

EID: 85009807601     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.17450     Document Type: Article

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