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Volumn 145, Issue , 2017, Pages 217-251

Regulation of Placental Amino Acid Transport and Fetal Growth

Author keywords

Adiponectin; Amino acid; Cortisol; Gestational diabetes; Insulin; Intrauterine growth restriction; Leptin; Obesity; Overgrowth; Placenta

Indexed keywords

ADIPOCYTOKINE; AMINO ACID; AMINO ACID TRANSPORTER; SOMATOMEDIN; STEROID HORMONE;

EID: 85009481206     PISSN: 18771173     EISSN: 18780814     Source Type: Book Series    
DOI: 10.1016/bs.pmbts.2016.12.008     Document Type: Chapter
Times cited : (86)

References (200)
  • 1
    • 33748257606 scopus 로고    scopus 로고
    • Perinatal outcome and later implications of intrauterine growth restriction
    • Pallotto, E.K., Kilbride, H.W., Perinatal outcome and later implications of intrauterine growth restriction. Clin Obstet Gynecol 49:2 (2006), 257–269.
    • (2006) Clin Obstet Gynecol , vol.49 , Issue.2 , pp. 257-269
    • Pallotto, E.K.1    Kilbride, H.W.2
  • 2
    • 38649113210 scopus 로고    scopus 로고
    • The macrosomic fetus: a challenge in current obstetrics
    • Henriksen, T., The macrosomic fetus: a challenge in current obstetrics. Acta Obstet Gynecol Scand 87:2 (2008), 134–145.
    • (2008) Acta Obstet Gynecol Scand , vol.87 , Issue.2 , pp. 134-145
    • Henriksen, T.1
  • 3
    • 10844241534 scopus 로고    scopus 로고
    • The developmental origins of chronic adult disease
    • Barker, D.J., The developmental origins of chronic adult disease. Acta Paediatr Suppl 93:446 (2004), 26–33.
    • (2004) Acta Paediatr Suppl , vol.93 , Issue.446 , pp. 26-33
    • Barker, D.J.1
  • 6
    • 0021173140 scopus 로고
    • Whole body and tissue fractional protein synthesis in the ovine fetus in utero
    • Schaefer, A.L., Krishnamurti, C.R., Whole body and tissue fractional protein synthesis in the ovine fetus in utero. Br J Nutr 52:2 (1984), 359–369.
    • (1984) Br J Nutr , vol.52 , Issue.2 , pp. 359-369
    • Schaefer, A.L.1    Krishnamurti, C.R.2
  • 8
    • 0036822310 scopus 로고    scopus 로고
    • Transport and metabolism of amino acids in placenta
    • Regnault, T.R., de Vrijer, B., Battaglia, F.C., Transport and metabolism of amino acids in placenta. Endocrine 19:1 (2002), 23–41.
    • (2002) Endocrine , vol.19 , Issue.1 , pp. 23-41
    • Regnault, T.R.1    de Vrijer, B.2    Battaglia, F.C.3
  • 10
    • 0025055255 scopus 로고
    • Umbilical amino acid concentrations in normal and growth-retarded fetuses sampled in utero by cordocentesis
    • Cetin, I., Corbetta, C., Sereni, L.P., et al. Umbilical amino acid concentrations in normal and growth-retarded fetuses sampled in utero by cordocentesis. Am J Obstet Gynecol 162:1 (1990), 253–261.
    • (1990) Am J Obstet Gynecol , vol.162 , Issue.1 , pp. 253-261
    • Cetin, I.1    Corbetta, C.2    Sereni, L.P.3
  • 11
    • 0030973093 scopus 로고    scopus 로고
    • Placental transport of threonine and its utilization in the normal and growth-restricted fetus
    • Anderson, A.H., Fennessey, P.V., Meschia, G., Wilkening, R.B., Battaglia, F.C., Placental transport of threonine and its utilization in the normal and growth-restricted fetus. Am J Physiol 272:5 pt 1 (1997), E892–E900.
    • (1997) Am J Physiol , vol.272 , Issue.5 , pp. E892-E900
    • Anderson, A.H.1    Fennessey, P.V.2    Meschia, G.3    Wilkening, R.B.4    Battaglia, F.C.5
  • 12
    • 0029984416 scopus 로고    scopus 로고
    • Placental transport and fetal utilization of leucine in a model of fetal growth retardation
    • Ross, J.C., Fennessey, P.V., Wilkening, R.B., Battaglia, F.C., Meschia, G., Placental transport and fetal utilization of leucine in a model of fetal growth retardation. Am J Physiol 270:3 pt 1 (1996), E491–E503.
    • (1996) Am J Physiol , vol.270 , Issue.3 , pp. E491-E503
    • Ross, J.C.1    Fennessey, P.V.2    Wilkening, R.B.3    Battaglia, F.C.4    Meschia, G.5
  • 13
    • 0035176558 scopus 로고    scopus 로고
    • Placental transport of leucine, phenylalanine, glycine, and proline in intrauterine growth-restricted pregnancies
    • Paolini, C.L., Marconi, A.M., Ronzoni, S., et al. Placental transport of leucine, phenylalanine, glycine, and proline in intrauterine growth-restricted pregnancies. J Clin Endocrinol Metab 86:11 (2001), 5427–5432.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.11 , pp. 5427-5432
    • Paolini, C.L.1    Marconi, A.M.2    Ronzoni, S.3
  • 14
    • 84879101946 scopus 로고    scopus 로고
    • Umbilical uptakes and transplacental concentration ratios of amino acids in severe fetal growth restriction
    • Regnault, T.R.H., de Vrijer, B., Galan, H.L., Wilkening, R.B., Battaglia, F.C., Meschia, G., Umbilical uptakes and transplacental concentration ratios of amino acids in severe fetal growth restriction. Pediatr Res 73:5 (2013), 602–611.
    • (2013) Pediatr Res , vol.73 , Issue.5 , pp. 602-611
    • Regnault, T.R.H.1    de Vrijer, B.2    Galan, H.L.3    Wilkening, R.B.4    Battaglia, F.C.5    Meschia, G.6
  • 15
    • 84984622423 scopus 로고    scopus 로고
    • Phenylalanine transfer across the isolated perfused human placenta: an experimental and modeling investigation
    • Lofthouse, E.M., Perazzolo, S., Brooks, S., et al. Phenylalanine transfer across the isolated perfused human placenta: an experimental and modeling investigation. Am J Physiol Regul Integr Comp Physiol 310:9 (2016), R828–R836.
    • (2016) Am J Physiol Regul Integr Comp Physiol , vol.310 , Issue.9 , pp. R828-R836
    • Lofthouse, E.M.1    Perazzolo, S.2    Brooks, S.3
  • 16
    • 0031909072 scopus 로고    scopus 로고
    • Production and utilization of amino acids by ovine placenta in vivo
    • Chung, M., Teng, C., Timmerman, M., Meschia, G., Battaglia, F.C., Production and utilization of amino acids by ovine placenta in vivo. Am J Physiol 274:1 pt 1 (1998), E13–E22.
    • (1998) Am J Physiol , vol.274 , Issue.1 , pp. E13-E22
    • Chung, M.1    Teng, C.2    Timmerman, M.3    Meschia, G.4    Battaglia, F.C.5
  • 17
    • 85042057387 scopus 로고    scopus 로고
    • Amino acid transfer in the fetal-placental unit: a human in vivo study. PLoS One. Submitted
    • Holm MB, Bastani NE, Holme AM, et al. Amino acid transfer in the fetal-placental unit: a human in vivo study. PLoS One. Submitted. 2016.
    • (2016)
    • Holm, M.B.1    Bastani, N.E.2    Holme, A.M.3
  • 18
    • 83155160802 scopus 로고    scopus 로고
    • Environmental regulation of placental phenotype: implications for fetal growth
    • Vaughan, O.R., Sferruzzi-Perri, A.N., Coan, P., Fowden, A., Environmental regulation of placental phenotype: implications for fetal growth. Reprod Fertil Dev 24 (2012), 1–17.
    • (2012) Reprod Fertil Dev , vol.24 , pp. 1-17
    • Vaughan, O.R.1    Sferruzzi-Perri, A.N.2    Coan, P.3    Fowden, A.4
  • 19
    • 84991573883 scopus 로고    scopus 로고
    • Placental metabolism: substrate requirements and response to stress
    • Vaughan, O.R., Fowden, A., Placental metabolism: substrate requirements and response to stress. Reprod Domest Anim 51:suppl 2 (2016), 1–11.
    • (2016) Reprod Domest Anim , vol.51 , pp. 1-11
    • Vaughan, O.R.1    Fowden, A.2
  • 20
    • 0029991575 scopus 로고    scopus 로고
    • Maternal concentrations and fetal-maternal concentration differences of plasma amino acids in normal and intrauterine growth-restricted pregnancies
    • Cetin, I., Ronzoni, S., Marconi, A.M., et al. Maternal concentrations and fetal-maternal concentration differences of plasma amino acids in normal and intrauterine growth-restricted pregnancies. Am J Obstet Gynecol 174:5 (1996), 1575–1583.
    • (1996) Am J Obstet Gynecol , vol.174 , Issue.5 , pp. 1575-1583
    • Cetin, I.1    Ronzoni, S.2    Marconi, A.M.3
  • 21
    • 0028796853 scopus 로고
    • Placental amino acid transport
    • Moe, A.J., Placental amino acid transport. Am J Physiol 268:6 pt 1 (1995), C1321–C1331.
    • (1995) Am J Physiol , vol.268 , Issue.6 , pp. C1321-C1331
    • Moe, A.J.1
  • 22
    • 41149135078 scopus 로고    scopus 로고
    • The mechanisms and regulation of placental amino acid transport to the human foetus
    • Cleal, J.K., Lewis, R.M., The mechanisms and regulation of placental amino acid transport to the human foetus. J Neuroendocrinol 20:4 (2008), 419–426.
    • (2008) J Neuroendocrinol , vol.20 , Issue.4 , pp. 419-426
    • Cleal, J.K.1    Lewis, R.M.2
  • 23
    • 79951709782 scopus 로고    scopus 로고
    • Facilitated transporters mediate net efflux of amino acids to the fetus across the basal membrane of the placental syncytiotrophoblast
    • Cleal, J.K., Glazier, J.D., Ntani, G., et al. Facilitated transporters mediate net efflux of amino acids to the fetus across the basal membrane of the placental syncytiotrophoblast. J Physiol 589:pt 4 (2011), 987–997.
    • (2011) J Physiol , vol.589 , pp. 987-997
    • Cleal, J.K.1    Glazier, J.D.2    Ntani, G.3
  • 24
    • 58149287671 scopus 로고    scopus 로고
    • The SNAT4 isoform of the system A amino acid transporter is functional in human placental microvillous plasma membrane
    • 11/1708/12/received, 11/11/accepted
    • Desforges, M., Mynett, K.J., Jones, R.L., et al. The SNAT4 isoform of the system A amino acid transporter is functional in human placental microvillous plasma membrane. J Physiol 587:pt 1 (2009), 61–72 11/1708/12/received, 11/11/accepted.
    • (2009) J Physiol , vol.587 , pp. 61-72
    • Desforges, M.1    Mynett, K.J.2    Jones, R.L.3
  • 25
    • 84937509609 scopus 로고    scopus 로고
    • Increased placental nutrient transport in a novel mouse model of maternal obesity with fetal overgrowth
    • Rosario, F.J., Kanai, Y., Powell, T.L., Jansson, T., Increased placental nutrient transport in a novel mouse model of maternal obesity with fetal overgrowth. Obesity 23:8 (2015), 1663–1670.
    • (2015) Obesity , vol.23 , Issue.8 , pp. 1663-1670
    • Rosario, F.J.1    Kanai, Y.2    Powell, T.L.3    Jansson, T.4
  • 26
    • 84899523121 scopus 로고    scopus 로고
    • Down-regulation of placental mTOR, insulin/IGF-I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon
    • Kavitha, J.V., Rosario, F.J., Nijland, M.J., et al. Down-regulation of placental mTOR, insulin/IGF-I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon. FASEB J 28:3 (2014), 1294–1305.
    • (2014) FASEB J , vol.28 , Issue.3 , pp. 1294-1305
    • Kavitha, J.V.1    Rosario, F.J.2    Nijland, M.J.3
  • 28
    • 0029830479 scopus 로고    scopus 로고
    • Ontogeny of amino acid transport system A in rat placenta
    • Novak, D.A., Beveridge, M.J., Malandro, M., Seo, J., Ontogeny of amino acid transport system A in rat placenta. Placenta 17:8 (1996), 643–651.
    • (1996) Placenta , vol.17 , Issue.8 , pp. 643-651
    • Novak, D.A.1    Beveridge, M.J.2    Malandro, M.3    Seo, J.4
  • 29
    • 80052493197 scopus 로고    scopus 로고
    • Antenatal dexamethasone treatment in midgestation reduces system A-mediated transport in the late-gestation murine placenta
    • Audette, M.C., Challis, J.R., Jones, R.L., Sibley, C.P., Matthews, S.G., Antenatal dexamethasone treatment in midgestation reduces system A-mediated transport in the late-gestation murine placenta. Endocrinology 152 (2011), 3561–3570.
    • (2011) Endocrinology , vol.152 , pp. 3561-3570
    • Audette, M.C.1    Challis, J.R.2    Jones, R.L.3    Sibley, C.P.4    Matthews, S.G.5
  • 30
    • 85019240454 scopus 로고    scopus 로고
    • Expression and functional characterisation of System L amino acid transporters in the human term placenta
    • Gaccioli, F., Aye, I.L., Roos, S., et al. Expression and functional characterisation of System L amino acid transporters in the human term placenta. Reprod Biol Endocrinol, 13, 2015, 57.
    • (2015) Reprod Biol Endocrinol , vol.13 , pp. 57
    • Gaccioli, F.1    Aye, I.L.2    Roos, S.3
  • 31
    • 84913534345 scopus 로고    scopus 로고
    • Computational modelling of amino acid exchange and facilitated transport in placental membrane vesicles
    • Panitchob, N., Widdows, K.L., Crocker, I.P., et al. Computational modelling of amino acid exchange and facilitated transport in placental membrane vesicles. J Theor Biol 365 (2015), 352–364.
    • (2015) J Theor Biol , vol.365 , pp. 352-364
    • Panitchob, N.1    Widdows, K.L.2    Crocker, I.P.3
  • 32
    • 77953645368 scopus 로고    scopus 로고
    • Computational modelling of amino acid transfer interactions in the placenta
    • Sengers, B.G., Please, C.P., Lewis, R.M., Computational modelling of amino acid transfer interactions in the placenta. Exp Physiol 95:7 (2010), 829–840.
    • (2010) Exp Physiol , vol.95 , Issue.7 , pp. 829-840
    • Sengers, B.G.1    Please, C.P.2    Lewis, R.M.3
  • 33
    • 84933544622 scopus 로고    scopus 로고
    • Integration of computational modeling with membrane transport studies reveals new insights into amino acid exchange transport mechanisms
    • Widdows, K.L., Panitchob, N., Crocker, I.P., et al. Integration of computational modeling with membrane transport studies reveals new insights into amino acid exchange transport mechanisms. FASEB J 29:6 (2015), 2583–2594.
    • (2015) FASEB J , vol.29 , Issue.6 , pp. 2583-2594
    • Widdows, K.L.1    Panitchob, N.2    Crocker, I.P.3
  • 34
    • 4644227801 scopus 로고    scopus 로고
    • Human placental taurine transporter in uncomplicated and IUGR pregnancies: cellular localization, protein expression, and regulation
    • Roos, S., Powell, T.L., Jansson, T., Human placental taurine transporter in uncomplicated and IUGR pregnancies: cellular localization, protein expression, and regulation. Am J Physiol Regul Integr Comp Physiol 287:4 (2004), R886–R893.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.287 , Issue.4 , pp. R886-R893
    • Roos, S.1    Powell, T.L.2    Jansson, T.3
  • 35
    • 71949093847 scopus 로고    scopus 로고
    • Isolation of plasma membrane vesicles from mouse placenta at term and measurement of system A and system beta amino acid transporter activity
    • Kusinski, L.C., Jones, C.J., Baker, P.N., Sibley, C.P., Glazier, J.D., Isolation of plasma membrane vesicles from mouse placenta at term and measurement of system A and system beta amino acid transporter activity. Placenta 31:1 (2010), 53–59.
    • (2010) Placenta , vol.31 , Issue.1 , pp. 53-59
    • Kusinski, L.C.1    Jones, C.J.2    Baker, P.N.3    Sibley, C.P.4    Glazier, J.D.5
  • 36
    • 0036169291 scopus 로고    scopus 로고
    • L-arginine transport by the microvillous plasma membrane of the syncytiotrophoblast from human placenta in relation to nitric oxide production: effects of gestation, preeclampsia, and intrauterine growth restriction
    • Ayuk, P.T., Theophanous, D., D'Souza, S.W., Sibley, C.P., Glazier, J.D., L-arginine transport by the microvillous plasma membrane of the syncytiotrophoblast from human placenta in relation to nitric oxide production: effects of gestation, preeclampsia, and intrauterine growth restriction. J Clin Endocrinol Metab 87:2 (2002), 747–751.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.2 , pp. 747-751
    • Ayuk, P.T.1    Theophanous, D.2    D'Souza, S.W.3    Sibley, C.P.4    Glazier, J.D.5
  • 37
    • 10644264309 scopus 로고    scopus 로고
    • Cationic amino acid transporter activity in the syncytiotrophoblast microvillous plasma membrane and oxygenation of the uteroplacental unit
    • Radaelli, T., Cetin, I., Ayuk, P.T., Glazier, J.D., Pardi, G., Sibley, C.P., Cationic amino acid transporter activity in the syncytiotrophoblast microvillous plasma membrane and oxygenation of the uteroplacental unit. Placenta 23:suppl A (2002), S69–S74.
    • (2002) Placenta , vol.23 , pp. S69-S74
    • Radaelli, T.1    Cetin, I.2    Ayuk, P.T.3    Glazier, J.D.4    Pardi, G.5    Sibley, C.P.6
  • 39
    • 0029781178 scopus 로고    scopus 로고
    • Effect of low-protein diet-induced intrauterine growth retardation on rat placental amino acid transport
    • Malandro, M.S., Beveridge, M.J., Kilberg, M.S., Novak, D.A., Effect of low-protein diet-induced intrauterine growth retardation on rat placental amino acid transport. Am J Physiol 271:1 pt 1 (1996), C295–C303.
    • (1996) Am J Physiol , vol.271 , Issue.1 , pp. C295-C303
    • Malandro, M.S.1    Beveridge, M.J.2    Kilberg, M.S.3    Novak, D.A.4
  • 40
    • 0030812757 scopus 로고    scopus 로고
    • Association between the activity of the system A amino acid transporter in the microvillous plasma membrane of the human placenta and severity of fetal compromise in intrauterine growth restriction
    • Glazier, J.D., Cetin, I., Perugino, G., et al. Association between the activity of the system A amino acid transporter in the microvillous plasma membrane of the human placenta and severity of fetal compromise in intrauterine growth restriction. Pediatr Res 42:4 (1997), 514–519.
    • (1997) Pediatr Res , vol.42 , Issue.4 , pp. 514-519
    • Glazier, J.D.1    Cetin, I.2    Perugino, G.3
  • 41
    • 0027458062 scopus 로고
    • Amino acid (system A) transporter activity in microvillous membrane vesicles from the placentas of appropriate and small for gestational age babies
    • Mahendran, D., Donnai, P., Glazier, J.D., D'Souza, S.W., Boyd, R.D., Sibley, C.P., Amino acid (system A) transporter activity in microvillous membrane vesicles from the placentas of appropriate and small for gestational age babies. Pediatr Res 34:5 (1993), 661–665.
    • (1993) Pediatr Res , vol.34 , Issue.5 , pp. 661-665
    • Mahendran, D.1    Donnai, P.2    Glazier, J.D.3    D'Souza, S.W.4    Boyd, R.D.5    Sibley, C.P.6
  • 42
    • 51249109258 scopus 로고    scopus 로고
    • Placental system A amino acid transport is reduced in pregnancies with small for gestational age (SGA) infants but not in preeclampsia with SGA infants
    • Shibata, E., Hubel, C.A., Powers, R.W., et al. Placental system A amino acid transport is reduced in pregnancies with small for gestational age (SGA) infants but not in preeclampsia with SGA infants. Placenta 29:10 (2008), 879–882.
    • (2008) Placenta , vol.29 , Issue.10 , pp. 879-882
    • Shibata, E.1    Hubel, C.A.2    Powers, R.W.3
  • 43
    • 84881260721 scopus 로고    scopus 로고
    • SNAT2 expression and regulation in human growth-restricted placentas
    • Mando, C., Tabano, S., Pileri, P., et al. SNAT2 expression and regulation in human growth-restricted placentas. Pediatr Res 74:2 (2013), 104–110.
    • (2013) Pediatr Res , vol.74 , Issue.2 , pp. 104-110
    • Mando, C.1    Tabano, S.2    Pileri, P.3
  • 44
    • 84964776819 scopus 로고    scopus 로고
    • Increased rat placental fatty acid, but decreased amino acid and glucose transporters potentially modify intrauterine programming
    • Nüsken, E., Gellhaus, A., Kühnel, E., et al. Increased rat placental fatty acid, but decreased amino acid and glucose transporters potentially modify intrauterine programming. J Cell Biochem 117:7 (2016), 1594–1603.
    • (2016) J Cell Biochem , vol.117 , Issue.7 , pp. 1594-1603
    • Nüsken, E.1    Gellhaus, A.2    Kühnel, E.3
  • 45
    • 0024997456 scopus 로고
    • Placental transfer of glucose and amino acids in intrauterine growth retardation: studies with substrate analogs in the awake guinea pig
    • Jansson, T., Persson, E., Placental transfer of glucose and amino acids in intrauterine growth retardation: studies with substrate analogs in the awake guinea pig. Pediatr Res 28:3 (1990), 203–208.
    • (1990) Pediatr Res , vol.28 , Issue.3 , pp. 203-208
    • Jansson, T.1    Persson, E.2
  • 46
    • 84863517530 scopus 로고    scopus 로고
    • eNOS knockout mouse as a model of fetal growth restriction with an impaired uterine artery function and placental transport phenotype
    • Kusinski, L.C., Stanley, J.L., Dilworth, M.R., et al. eNOS knockout mouse as a model of fetal growth restriction with an impaired uterine artery function and placental transport phenotype. Am J Physiol Regul Integr Comp Physiol 303:1 (2012), R86–R93.
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.303 , Issue.1 , pp. R86-R93
    • Kusinski, L.C.1    Stanley, J.L.2    Dilworth, M.R.3
  • 47
    • 0029888553 scopus 로고    scopus 로고
    • Effect of fetal growth restriction on system A amino acid transporter activity in the maternal facing plasma membrane of rat syncytiotrophoblast
    • Glazier, J.D., Sibley, C.P., Carter, A.M., Effect of fetal growth restriction on system A amino acid transporter activity in the maternal facing plasma membrane of rat syncytiotrophoblast. Pediatr Res 40:2 (1996), 325–329.
    • (1996) Pediatr Res , vol.40 , Issue.2 , pp. 325-329
    • Glazier, J.D.1    Sibley, C.P.2    Carter, A.M.3
  • 48
    • 0036078274 scopus 로고    scopus 로고
    • Physiological importance of system A-mediated amino acid transport to rat fetal development
    • Cramer, S., Beveridge, M., Kilberg, M., Novak, D., Physiological importance of system A-mediated amino acid transport to rat fetal development. Am J Physiol Cell Physiol 282:1 (2002), C153–C160.
    • (2002) Am J Physiol Cell Physiol , vol.282 , Issue.1 , pp. C153-C160
    • Cramer, S.1    Beveridge, M.2    Kilberg, M.3    Novak, D.4
  • 49
    • 0031670272 scopus 로고    scopus 로고
    • Placental transport of leucine and lysine is reduced in intrauterine growth restriction
    • Jansson, T., Scholtbach, V., Powell, T.L., Placental transport of leucine and lysine is reduced in intrauterine growth restriction. Pediatr Res 44:4 (1998), 532–537.
    • (1998) Pediatr Res , vol.44 , Issue.4 , pp. 532-537
    • Jansson, T.1    Scholtbach, V.2    Powell, T.L.3
  • 50
    • 0031850059 scopus 로고    scopus 로고
    • Intrauterine growth restriction is associated with a reduced activity of placental taurine transporters
    • Norberg, S., Powell, T.L., Jansson, T., Intrauterine growth restriction is associated with a reduced activity of placental taurine transporters. Pediatr Res 44:2 (1998), 233–238.
    • (1998) Pediatr Res , vol.44 , Issue.2 , pp. 233-238
    • Norberg, S.1    Powell, T.L.2    Jansson, T.3
  • 51
    • 84902545379 scopus 로고    scopus 로고
    • Differential levels of amino acid transporters System L and ASCT2, and the mTOR protein in placenta of preeclampsia and IUGR
    • Aiko, Y., Askew, D.J., Aramaki, S., et al. Differential levels of amino acid transporters System L and ASCT2, and the mTOR protein in placenta of preeclampsia and IUGR. BMC Pregnancy Childbirth, 14, 2014, 181.
    • (2014) BMC Pregnancy Childbirth , vol.14 , pp. 181
    • Aiko, Y.1    Askew, D.J.2    Aramaki, S.3
  • 52
    • 8644282099 scopus 로고    scopus 로고
    • Placental uptake and transport of ACP, a neutral nonmetabolizable amino acid, in an ovine model of fetal growth restriction
    • de Vrijer, B., Regnault, T.R., Wilkening, R.B., Meschia, G., Battaglia, F.C., Placental uptake and transport of ACP, a neutral nonmetabolizable amino acid, in an ovine model of fetal growth restriction. Am J Physiol Endocrinol Metab 287:6 (2004), E1114–E1124.
    • (2004) Am J Physiol Endocrinol Metab , vol.287 , Issue.6 , pp. E1114-E1124
    • de Vrijer, B.1    Regnault, T.R.2    Wilkening, R.B.3    Meschia, G.4    Battaglia, F.C.5
  • 53
    • 0036307306 scopus 로고    scopus 로고
    • Alterations in the activity of placental amino acid transporters in pregnancies complicated by diabetes
    • Jansson, T., Ekstrand, Y., Bjorn, C., Wennergren, M., Powell, T.L., Alterations in the activity of placental amino acid transporters in pregnancies complicated by diabetes. Diabetes 51:7 (2002), 2214–2219.
    • (2002) Diabetes , vol.51 , Issue.7 , pp. 2214-2219
    • Jansson, T.1    Ekstrand, Y.2    Bjorn, C.3    Wennergren, M.4    Powell, T.L.5
  • 54
    • 84872068779 scopus 로고    scopus 로고
    • Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies
    • Jansson, N., Rosario, F.J., Gaccioli, F., et al. Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies. J Clin Endocrinol Metab 98:1 (2013), 105–113.
    • (2013) J Clin Endocrinol Metab , vol.98 , Issue.1 , pp. 105-113
    • Jansson, N.1    Rosario, F.J.2    Gaccioli, F.3
  • 55
    • 58249102098 scopus 로고    scopus 로고
    • High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice
    • Jones, H.N., Woollett, L.A., Barbour, N., Prasad, P.D., Powell, T.L., Jansson, T., High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice. FASEB J 23:1 (2009), 271–278.
    • (2009) FASEB J , vol.23 , Issue.1 , pp. 271-278
    • Jones, H.N.1    Woollett, L.A.2    Barbour, N.3    Prasad, P.D.4    Powell, T.L.5    Jansson, T.6
  • 57
    • 62749102667 scopus 로고    scopus 로고
    • The hungry fetus? Role of leptin as a nutritional signal before birth
    • Forhead, A.J., Fowden, A.L., The hungry fetus? Role of leptin as a nutritional signal before birth. J Physiol 587:pt 6 (2009), 1145–1152.
    • (2009) J Physiol , vol.587 , pp. 1145-1152
    • Forhead, A.J.1    Fowden, A.L.2
  • 59
    • 84983000118 scopus 로고    scopus 로고
    • Knockout maternal adiponectin increases fetal growth in mice: potential role for trophoblast IGFBP-1
    • Qiao, L., Wattez, J.S., Lee, S., et al. Knockout maternal adiponectin increases fetal growth in mice: potential role for trophoblast IGFBP-1. Diabetologia 59 (2016), 2417–2425.
    • (2016) Diabetologia , vol.59 , pp. 2417-2425
    • Qiao, L.1    Wattez, J.S.2    Lee, S.3
  • 60
    • 84870354052 scopus 로고    scopus 로고
    • Adiponectin enhances mouse fetal fat deposition
    • Qiao, L., Yoo, H.S., Madon, A., Kinney, B., Hay, W.W., Shao, J., Adiponectin enhances mouse fetal fat deposition. Diabetes 61:12 (2012), 3199–3207.
    • (2012) Diabetes , vol.61 , Issue.12 , pp. 3199-3207
    • Qiao, L.1    Yoo, H.S.2    Madon, A.3    Kinney, B.4    Hay, W.W.5    Shao, J.6
  • 62
    • 0024538062 scopus 로고
    • Differential expression of the receptors for epidermal growth factor and insulin in the developing human placenta
    • Tavare, J.M., Holmes, C.H., Differential expression of the receptors for epidermal growth factor and insulin in the developing human placenta. Cell Signal 1:1 (1989), 55–64.
    • (1989) Cell Signal , vol.1 , Issue.1 , pp. 55-64
    • Tavare, J.M.1    Holmes, C.H.2
  • 63
    • 0028181069 scopus 로고
    • Insulin receptors in syncytiotrophoblast and fetal endothelium of human placenta. Immunohistochemical evidence for developmental changes in distribution pattern
    • Desoye, G., Hartmann, M., Blaschitz, A., et al. Insulin receptors in syncytiotrophoblast and fetal endothelium of human placenta. Immunohistochemical evidence for developmental changes in distribution pattern. Histochemistry 101:4 (1994), 277–285.
    • (1994) Histochemistry , vol.101 , Issue.4 , pp. 277-285
    • Desoye, G.1    Hartmann, M.2    Blaschitz, A.3
  • 64
    • 0031013187 scopus 로고    scopus 로고
    • Spatial polarization of insulin-like growth factor receptors on the human syncytiotrophoblast
    • Fang, J., Furesz, T.C., Lurent, R.S., Smith, C.H., Fant, M.E., Spatial polarization of insulin-like growth factor receptors on the human syncytiotrophoblast. Pediatr Res 41:2 (1997), 258–265.
    • (1997) Pediatr Res , vol.41 , Issue.2 , pp. 258-265
    • Fang, J.1    Furesz, T.C.2    Lurent, R.S.3    Smith, C.H.4    Fant, M.E.5
  • 65
    • 0032858893 scopus 로고    scopus 로고
    • Leptin receptor in human term placenta: in situ hybridization and immunohistochemical localization
    • Bodner, J., Ebenbichler, C.F., Wolf, H.J., et al. Leptin receptor in human term placenta: in situ hybridization and immunohistochemical localization. Placenta 20:8 (1999), 677–682.
    • (1999) Placenta , vol.20 , Issue.8 , pp. 677-682
    • Bodner, J.1    Ebenbichler, C.F.2    Wolf, H.J.3
  • 66
    • 84962706638 scopus 로고    scopus 로고
    • Placental responses to changes in the maternal environment determine fetal growth
    • Dimasuay, K.G., Boeuf, P., Powell, T.L., Jansson, T., Placental responses to changes in the maternal environment determine fetal growth. Front Physiol, 7, 2016, 12.
    • (2016) Front Physiol , vol.7 , pp. 12
    • Dimasuay, K.G.1    Boeuf, P.2    Powell, T.L.3    Jansson, T.4
  • 67
    • 84928326971 scopus 로고    scopus 로고
    • The role of placental nutrient sensing in maternal-fetal resource allocation
    • Diaz, P., Powell, T.L., Jansson, T., The role of placental nutrient sensing in maternal-fetal resource allocation. Biol Reprod, 91, 2014, 82.
    • (2014) Biol Reprod , vol.91 , pp. 82
    • Diaz, P.1    Powell, T.L.2    Jansson, T.3
  • 68
    • 43249096940 scopus 로고    scopus 로고
    • Hyperglycemia and adverse pregnancy outcomes
    • Metzger, B.E., Lowe, L.P., Dyer, A.R., et al. Hyperglycemia and adverse pregnancy outcomes. N Engl J Med 358:19 (2008), 1991–2002.
    • (2008) N Engl J Med , vol.358 , Issue.19 , pp. 1991-2002
    • Metzger, B.E.1    Lowe, L.P.2    Dyer, A.R.3
  • 69
    • 55849144881 scopus 로고    scopus 로고
    • Maternal lipids as strong determinants of fetal environment and growth in pregnancies with gestational diabetes mellitus
    • Schaefer-Graf, U.M., Graf, K., Kulbacka, I., et al. Maternal lipids as strong determinants of fetal environment and growth in pregnancies with gestational diabetes mellitus. Diabetes Care 31:9 (2008), 1858–1863.
    • (2008) Diabetes Care , vol.31 , Issue.9 , pp. 1858-1863
    • Schaefer-Graf, U.M.1    Graf, K.2    Kulbacka, I.3
  • 70
    • 71449099638 scopus 로고    scopus 로고
    • Enhanced circulating retinol and non-esterified fatty acids in pregnancies complicated with intrauterine growth restriction
    • Ortega-Senovilla, H., Alvino, G., Taricco, E., Cetin, I., Herrera, E., Enhanced circulating retinol and non-esterified fatty acids in pregnancies complicated with intrauterine growth restriction. Clin Sci (Lond) 118:5 (2010), 351–358.
    • (2010) Clin Sci (Lond) , vol.118 , Issue.5 , pp. 351-358
    • Ortega-Senovilla, H.1    Alvino, G.2    Taricco, E.3    Cetin, I.4    Herrera, E.5
  • 72
    • 84880372266 scopus 로고    scopus 로고
    • L-Methionine placental uptake: characterization and modulation in gestational diabetes mellitus
    • Araújo, J.R., Correia-Branco, A., Ramalho, C., et al. L-Methionine placental uptake: characterization and modulation in gestational diabetes mellitus. Reprod Sci 20:12 (2013), 1492–1507.
    • (2013) Reprod Sci , vol.20 , Issue.12 , pp. 1492-1507
    • Araújo, J.R.1    Correia-Branco, A.2    Ramalho, C.3
  • 73
    • 84927089411 scopus 로고    scopus 로고
    • Maternal obesity is associated with a reduction in placental taurine transporter activity (2005)
    • Ditchfield, A.M., Desforges, M., Mills, T.A., et al. Maternal obesity is associated with a reduction in placental taurine transporter activity (2005). Int J Obes (Lond) 39:4 (2015), 557–564.
    • (2015) Int J Obes (Lond) , vol.39 , Issue.4 , pp. 557-564
    • Ditchfield, A.M.1    Desforges, M.2    Mills, T.A.3
  • 74
    • 45749103595 scopus 로고    scopus 로고
    • Maternal hormones linking maternal body mass index and dietary intake to birth weight
    • Jansson, N., Nilsfelt, A., Gellerstedt, M., et al. Maternal hormones linking maternal body mass index and dietary intake to birth weight. Am J Clin Nutr 87:6 (2008), 1743–1749.
    • (2008) Am J Clin Nutr , vol.87 , Issue.6 , pp. 1743-1749
    • Jansson, N.1    Nilsfelt, A.2    Gellerstedt, M.3
  • 75
    • 77955981879 scopus 로고    scopus 로고
    • Placental amino acid transport and placental leptin resistance in pregnancies complicated by maternal obesity
    • Farley, D.M., Choi, J., Dudley, D.J., et al. Placental amino acid transport and placental leptin resistance in pregnancies complicated by maternal obesity. Placenta 31:8 (2010), 718–724.
    • (2010) Placenta , vol.31 , Issue.8 , pp. 718-724
    • Farley, D.M.1    Choi, J.2    Dudley, D.J.3
  • 76
    • 69549123892 scopus 로고    scopus 로고
    • Feto-placental adaptations to maternal obesity in the baboon
    • Farley, D., Tejero, M.E., Comuzzie, A.G., et al. Feto-placental adaptations to maternal obesity in the baboon. Placenta 30:9 (2009), 752–760.
    • (2009) Placenta , vol.30 , Issue.9 , pp. 752-760
    • Farley, D.1    Tejero, M.E.2    Comuzzie, A.G.3
  • 77
    • 84874059710 scopus 로고    scopus 로고
    • Oleic acid stimulates system A amino acid transport in primary human trophoblast cells mediated by toll-like receptor 4
    • Lager, S., Gaccioli, F., Ramirez, V.I., Jones, H.N., Jansson, T., Powell, T.L., Oleic acid stimulates system A amino acid transport in primary human trophoblast cells mediated by toll-like receptor 4. J Lipid Res 54:3 (2013), 725–733.
    • (2013) J Lipid Res , vol.54 , Issue.3 , pp. 725-733
    • Lager, S.1    Gaccioli, F.2    Ramirez, V.I.3    Jones, H.N.4    Jansson, T.5    Powell, T.L.6
  • 78
    • 84908052375 scopus 로고    scopus 로고
    • Differential regulation of placental amino acid transport by saturated and unsaturated fatty acids
    • Lager, S., Jansson, T., Powell, T.L., Differential regulation of placental amino acid transport by saturated and unsaturated fatty acids. Am J Physiol Cell Physiol 307:8 (2014), C738–C744.
    • (2014) Am J Physiol Cell Physiol , vol.307 , Issue.8 , pp. C738-C744
    • Lager, S.1    Jansson, T.2    Powell, T.L.3
  • 79
    • 70349246381 scopus 로고    scopus 로고
    • Regulation of amino acid transporters by glucose and growth factors in cultured primary human trophoblast cells is mediated by mTOR signaling
    • Roos, S., Lagerlof, O., Wennergren, M., Powell, T.L., Jansson, T., Regulation of amino acid transporters by glucose and growth factors in cultured primary human trophoblast cells is mediated by mTOR signaling. Am J Physiol Cell Physiol 297:3 (2009), C723–C731.
    • (2009) Am J Physiol Cell Physiol , vol.297 , Issue.3 , pp. C723-C731
    • Roos, S.1    Lagerlof, O.2    Wennergren, M.3    Powell, T.L.4    Jansson, T.5
  • 80
    • 33744501519 scopus 로고    scopus 로고
    • Expression and adaptive regulation of amino acid transport system A in a placental cell line under amino acid restriction
    • Jones, H.N., Ashworth, C.J., Page, K.R., McArdle, H.J., Expression and adaptive regulation of amino acid transport system A in a placental cell line under amino acid restriction. Reproduction 131:5 (2006), 951–960.
    • (2006) Reproduction , vol.131 , Issue.5 , pp. 951-960
    • Jones, H.N.1    Ashworth, C.J.2    Page, K.R.3    McArdle, H.J.4
  • 81
    • 27944464141 scopus 로고    scopus 로고
    • Impact of forskolin and amino acid depletion upon System A activity and SNAT expression in BeWo cells
    • Novak, D., Quiggle, F., Haafiz, A., Impact of forskolin and amino acid depletion upon System A activity and SNAT expression in BeWo cells. Biochimie 88:1 (2006), 39–44.
    • (2006) Biochimie , vol.88 , Issue.1 , pp. 39-44
    • Novak, D.1    Quiggle, F.2    Haafiz, A.3
  • 82
    • 0037303394 scopus 로고    scopus 로고
    • Hypoxia reduces expression and function of system A amino acid transporters in cultured term human trophoblasts
    • Nelson, D.M., Smith, S.D., Furesz, T.C., et al. Hypoxia reduces expression and function of system A amino acid transporters in cultured term human trophoblasts. Am J Physiol Cell Physiol 284:2 (2003), C310–C315.
    • (2003) Am J Physiol Cell Physiol , vol.284 , Issue.2 , pp. C310-C315
    • Nelson, D.M.1    Smith, S.D.2    Furesz, T.C.3
  • 83
    • 0037342788 scopus 로고    scopus 로고
    • Leptin stimulates the activity of the system A amino acid transporter in human placental villous fragments
    • Jansson, N., Greenwood, S.L., Johansson, B.R., Powell, T.L., Jansson, T., Leptin stimulates the activity of the system A amino acid transporter in human placental villous fragments. J Clin Endocrinol Metab 88:3 (2003), 1205–1211.
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.3 , pp. 1205-1211
    • Jansson, N.1    Greenwood, S.L.2    Johansson, B.R.3    Powell, T.L.4    Jansson, T.5
  • 84
    • 0026509437 scopus 로고
    • Amino acid transport by the cultured human placental trophoblast: effect of insulin on AIB transport
    • Karl, P.I., Alpy, K.L., Fisher, S.E., Amino acid transport by the cultured human placental trophoblast: effect of insulin on AIB transport. Am J Physiol 262:4 pt 1 (1992), C834–C839.
    • (1992) Am J Physiol , vol.262 , Issue.4 , pp. C834-C839
    • Karl, P.I.1    Alpy, K.L.2    Fisher, S.E.3
  • 85
    • 62249137040 scopus 로고    scopus 로고
    • Leptin affects system A amino acid transport activity in the human placenta: evidence for STAT3 dependent mechanisms
    • von Versen-Hoynck, F., Rajakumar, A., Parrott, M.S., Powers, R.W., Leptin affects system A amino acid transport activity in the human placenta: evidence for STAT3 dependent mechanisms. Placenta 30:4 (2009), 361–367.
    • (2009) Placenta , vol.30 , Issue.4 , pp. 361-367
    • von Versen-Hoynck, F.1    Rajakumar, A.2    Parrott, M.S.3    Powers, R.W.4
  • 86
    • 84956595879 scopus 로고    scopus 로고
    • TNF-α stimulates System A amino acid transport in primary human trophoblast cells mediated by p38 MAPK signaling
    • Aye, I.L.M.H., Jansson, T., Powell, T.L., TNF-α stimulates System A amino acid transport in primary human trophoblast cells mediated by p38 MAPK signaling. Physiol Rep, 3(10), 2015, e12594.
    • (2015) Physiol Rep , vol.3 , Issue.10 , pp. e12594
    • Aye, I.L.M.H.1    Jansson, T.2    Powell, T.L.3
  • 87
    • 70449623354 scopus 로고    scopus 로고
    • IL-6 stimulates system A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2
    • Jones, H.N., Jansson, T., Powell, T.L., IL-6 stimulates system A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2. Am J Physiol Cell Physiol 297:5 (2009), C1228–C1235.
    • (2009) Am J Physiol Cell Physiol , vol.297 , Issue.5 , pp. C1228-C1235
    • Jones, H.N.1    Jansson, T.2    Powell, T.L.3
  • 88
    • 84882751390 scopus 로고    scopus 로고
    • Interleukin-1β inhibits insulin signaling and prevents insulin-stimulated system A amino acid transport in primary human trophoblasts
    • Aye, I.L.M.H., Jansson, T., Powell, T.L., Interleukin-1β inhibits insulin signaling and prevents insulin-stimulated system A amino acid transport in primary human trophoblasts. Mol Cell Endocrinol 381:1–2 (2013), 46–55.
    • (2013) Mol Cell Endocrinol , vol.381 , Issue.1-2 , pp. 46-55
    • Aye, I.L.M.H.1    Jansson, T.2    Powell, T.L.3
  • 89
    • 77951860161 scopus 로고    scopus 로고
    • Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino acid transport in human primary trophoblast cells
    • Jones, H.N., Jansson, T., Powell, T.L., Full-length adiponectin attenuates insulin signaling and inhibits insulin-stimulated amino acid transport in human primary trophoblast cells. Diabetes 59:5 (2010), 1161–1170.
    • (2010) Diabetes , vol.59 , Issue.5 , pp. 1161-1170
    • Jones, H.N.1    Jansson, T.2    Powell, T.L.3
  • 90
    • 33748446807 scopus 로고    scopus 로고
    • Cortisol stimulates system A amino acid transport and SNAT2 expression in a human placental cell line (BeWo)
    • Jones, H.N., Ashworth, C.J., Page, K.R., McArdle, H.J., Cortisol stimulates system A amino acid transport and SNAT2 expression in a human placental cell line (BeWo). Am J Physiol Endocrinol Metab 291:3 (2006), E596–E603.
    • (2006) Am J Physiol Endocrinol Metab , vol.291 , Issue.3 , pp. E596-E603
    • Jones, H.N.1    Ashworth, C.J.2    Page, K.R.3    McArdle, H.J.4
  • 91
    • 75049084765 scopus 로고    scopus 로고
    • Dexamethasone stimulates placental system A transport and trophoblast differentiation in term villous explants
    • Audette, M.C., Greenwood, S.L., Sibley, C.P., et al. Dexamethasone stimulates placental system A transport and trophoblast differentiation in term villous explants. Placenta 31:2 (2010), 97–105.
    • (2010) Placenta , vol.31 , Issue.2 , pp. 97-105
    • Audette, M.C.1    Greenwood, S.L.2    Sibley, C.P.3
  • 92
    • 33751183770 scopus 로고    scopus 로고
    • Angiotensin II decreases system A amino acid transporter activity in human placental villous fragments through AT1 receptor activation
    • Shibata, E., Powers, R.W., Rajakumar, A., et al. Angiotensin II decreases system A amino acid transporter activity in human placental villous fragments through AT1 receptor activation. Am J Physiol Endocrinol Metab 291:5 (2006), E1009–E1016.
    • (2006) Am J Physiol Endocrinol Metab , vol.291 , Issue.5 , pp. E1009-E1016
    • Shibata, E.1    Powers, R.W.2    Rajakumar, A.3
  • 93
    • 84885154609 scopus 로고    scopus 로고
    • An obesogenic diet during mouse pregnancy modifies maternal nutrient partitioning and the fetal growth trajectory
    • Sferruzzi-Perri, A.N., Vaughan, O.R., Haro, M., et al. An obesogenic diet during mouse pregnancy modifies maternal nutrient partitioning and the fetal growth trajectory. FASEB J 27:10 (2013), 3928–3937.
    • (2013) FASEB J , vol.27 , Issue.10 , pp. 3928-3937
    • Sferruzzi-Perri, A.N.1    Vaughan, O.R.2    Haro, M.3
  • 94
    • 85042043018 scopus 로고    scopus 로고
    • A Western-style obesogenic diet causes maternal metabolic dysfunction with consequences for fetal nutrient acquisition in mice
    • Submitted
    • Musial, B., Vaughan, O.R., Fernandez-Twinn, D.S., et al. A Western-style obesogenic diet causes maternal metabolic dysfunction with consequences for fetal nutrient acquisition in mice. J Physiol, 2016 Submitted.
    • (2016) J Physiol
    • Musial, B.1    Vaughan, O.R.2    Fernandez-Twinn, D.S.3
  • 95
    • 84944111953 scopus 로고    scopus 로고
    • Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth
    • Aye, I.L.M.H., Rosario, F.J., Powell, T.L., Jansson, T., Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth. Proc Natl Acad Sci USA 112:41 (2015), 12858–12863.
    • (2015) Proc Natl Acad Sci USA , vol.112 , Issue.41 , pp. 12858-12863
    • Aye, I.L.M.H.1    Rosario, F.J.2    Powell, T.L.3    Jansson, T.4
  • 96
    • 75649095675 scopus 로고    scopus 로고
    • Adaptations in placental phenotype support fetal growth during undernutrition of pregnant mice
    • Coan, P.M., Vaughan, O.R., Sekita, Y., et al. Adaptations in placental phenotype support fetal growth during undernutrition of pregnant mice. J Physiol 588:pt 3 (2010), 527–538.
    • (2010) J Physiol , vol.588 , pp. 527-538
    • Coan, P.M.1    Vaughan, O.R.2    Sekita, Y.3
  • 97
    • 79960727937 scopus 로고    scopus 로고
    • Placental-specific Igf2 deficiency alters developmental adaptations to undernutrition in mice
    • Sferruzzi-Perri, A.N., Vaughan, O.R., Coan, P.M., et al. Placental-specific Igf2 deficiency alters developmental adaptations to undernutrition in mice. Endocrinology 152 (2011), 3202–3212.
    • (2011) Endocrinology , vol.152 , pp. 3202-3212
    • Sferruzzi-Perri, A.N.1    Vaughan, O.R.2    Coan, P.M.3
  • 98
    • 84864392488 scopus 로고    scopus 로고
    • Placental glucose and amino acid transport in calorie-restricted wild-type and Glut3 null heterozygous mice
    • Ganguly, A., Collis, L., Devaskar, S.U., Placental glucose and amino acid transport in calorie-restricted wild-type and Glut3 null heterozygous mice. Endocrinology 153:8 (2012), 3995–4007.
    • (2012) Endocrinology , vol.153 , Issue.8 , pp. 3995-4007
    • Ganguly, A.1    Collis, L.2    Devaskar, S.U.3
  • 99
    • 0019769087 scopus 로고
    • Effect of maternal dietary restriction on fetal growth and placental transfer of alpha-amino isobutyric acid in rats
    • Ahokas, R.A., Lahaye, E.B., Anderson, G.D., Lipshitz, J., Effect of maternal dietary restriction on fetal growth and placental transfer of alpha-amino isobutyric acid in rats. J Nutr 111:12 (1981), 2052–2058.
    • (1981) J Nutr , vol.111 , Issue.12 , pp. 2052-2058
    • Ahokas, R.A.1    Lahaye, E.B.2    Anderson, G.D.3    Lipshitz, J.4
  • 100
    • 79960358640 scopus 로고    scopus 로고
    • Dietary composition programmes placental phenotype in mice
    • Coan, P.M., Vaughan, O.R., McCarthy, J., et al. Dietary composition programmes placental phenotype in mice. J Physiol 589 (2011), 3659–3670.
    • (2011) J Physiol , vol.589 , pp. 3659-3670
    • Coan, P.M.1    Vaughan, O.R.2    McCarthy, J.3
  • 101
    • 33750426477 scopus 로고    scopus 로고
    • Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet
    • Jansson, N., Pettersson, J., Haafiz, A., et al. Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet. J Physiol 576:pt 3 (2006), 935–946.
    • (2006) J Physiol , vol.576 , pp. 935-946
    • Jansson, N.1    Pettersson, J.2    Haafiz, A.3
  • 102
    • 79951938584 scopus 로고    scopus 로고
    • Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters
    • Rosario, F.J., Jansson, N., Kanai, Y., Prasad, P.D., Powell, T.L., Jansson, T., Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters. Endocrinology 152 (2011), 1119–1129.
    • (2011) Endocrinology , vol.152 , pp. 1119-1129
    • Rosario, F.J.1    Jansson, N.2    Kanai, Y.3    Prasad, P.D.4    Powell, T.L.5    Jansson, T.6
  • 103
    • 0025915917 scopus 로고
    • Effects of protein-calorie malnutrition on transplacental kinetics of aminoisobutyric acid in rats
    • Varma, D.R., Ramakrishnan, R., Effects of protein-calorie malnutrition on transplacental kinetics of aminoisobutyric acid in rats. Placenta 12:3 (1991), 277–284.
    • (1991) Placenta , vol.12 , Issue.3 , pp. 277-284
    • Varma, D.R.1    Ramakrishnan, R.2
  • 104
    • 84959294504 scopus 로고    scopus 로고
    • Placental phenotype and resource allocation to fetal growth are modified by the timing and degree of hypoxia during mouse pregnancy
    • Higgins, J.S., Vaughan, O.R., Fernandez de Liger, E., Fowden, A.L., Sferruzzi-Perri, A.N., Placental phenotype and resource allocation to fetal growth are modified by the timing and degree of hypoxia during mouse pregnancy. J Physiol 594 (2016), 1341–1356.
    • (2016) J Physiol , vol.594 , pp. 1341-1356
    • Higgins, J.S.1    Vaughan, O.R.2    Fernandez de Liger, E.3    Fowden, A.L.4    Sferruzzi-Perri, A.N.5
  • 105
    • 84858237689 scopus 로고    scopus 로고
    • Chronic maternal infusion of full-length adiponectin in pregnant mice down-regulates placental amino acid transporter activity and expression and decreases fetal growth
    • Rosario, F.J., Schumacher, M.A., Jiang, J., Kanai, Y., Powell, T.L., Jansson, T., Chronic maternal infusion of full-length adiponectin in pregnant mice down-regulates placental amino acid transporter activity and expression and decreases fetal growth. J Physiol 590:6 (2012), 1495–1509.
    • (2012) J Physiol , vol.590 , Issue.6 , pp. 1495-1509
    • Rosario, F.J.1    Schumacher, M.A.2    Jiang, J.3    Kanai, Y.4    Powell, T.L.5    Jansson, T.6
  • 106
    • 79961012666 scopus 로고    scopus 로고
    • Prenatal testosterone-induced fetal growth restriction is associated with down-regulation of rat placental amino acid transport
    • Sathishkumar, K., Elkins, R., Chinnathambi, V., Gao, H., Hankins, G.D., Yallampalli, C., Prenatal testosterone-induced fetal growth restriction is associated with down-regulation of rat placental amino acid transport. Reprod Biol Endocrinol 9:1 (2011), 1–12.
    • (2011) Reprod Biol Endocrinol , vol.9 , Issue.1 , pp. 1-12
    • Sathishkumar, K.1    Elkins, R.2    Chinnathambi, V.3    Gao, H.4    Hankins, G.D.5    Yallampalli, C.6
  • 107
    • 84868148271 scopus 로고    scopus 로고
    • Maternal corticosterone regulates nutrient allocation to fetal growth in mice
    • Vaughan, O.R., Sferruzzi-Perri, A.N., Fowden, A.L., Maternal corticosterone regulates nutrient allocation to fetal growth in mice. J Physiol 590 (2012), 5529–5540.
    • (2012) J Physiol , vol.590 , pp. 5529-5540
    • Vaughan, O.R.1    Sferruzzi-Perri, A.N.2    Fowden, A.L.3
  • 108
    • 84899838348 scopus 로고    scopus 로고
    • Adaptations in placental phenotype depend on route and timing of maternal dexamethasone administration in mice
    • Vaughan, O.R., Sferruzzi-Perri, A.N., Coan, P.M., Fowden, A.L., Adaptations in placental phenotype depend on route and timing of maternal dexamethasone administration in mice. Biol Reprod, 89(4), 2013, 80.
    • (2013) Biol Reprod , vol.89 , Issue.4 , pp. 80
    • Vaughan, O.R.1    Sferruzzi-Perri, A.N.2    Coan, P.M.3    Fowden, A.L.4
  • 109
    • 0345205653 scopus 로고    scopus 로고
    • Blood pressure in adults after prenatal exposure to famine
    • Roseboom, T.J., van der Meulen, J.H., Ravelli, A.C., et al. Blood pressure in adults after prenatal exposure to famine. J Hypertens 17:3 (1999), 325–330.
    • (1999) J Hypertens , vol.17 , Issue.3 , pp. 325-330
    • Roseboom, T.J.1    van der Meulen, J.H.2    Ravelli, A.C.3
  • 110
    • 0031034219 scopus 로고    scopus 로고
    • Leucine metabolism in chronically hypoglycemic hypoinsulinemic growth-restricted fetal sheep
    • Carver, T.D., Quick, A.A., Teng, C.C., Pike, A.W., Fennessey, P.V., Hay, W.W. Jr., Leucine metabolism in chronically hypoglycemic hypoinsulinemic growth-restricted fetal sheep. Am J Physiol 272:1 pt 1 (1997), E107–E117.
    • (1997) Am J Physiol , vol.272 , Issue.1 , pp. E107-E117
    • Carver, T.D.1    Quick, A.A.2    Teng, C.C.3    Pike, A.W.4    Fennessey, P.V.5    Hay, W.W.6
  • 111
    • 0023224870 scopus 로고
    • Effect of restriction of placental growth on oxygen delivery to and consumption by the pregnant uterus and fetus
    • Owens, J.A., Falconer, J., Robinson, J.S., Effect of restriction of placental growth on oxygen delivery to and consumption by the pregnant uterus and fetus. J Dev Physiol 9:2 (1987), 137–150.
    • (1987) J Dev Physiol , vol.9 , Issue.2 , pp. 137-150
    • Owens, J.A.1    Falconer, J.2    Robinson, J.S.3
  • 112
    • 85006056317 scopus 로고    scopus 로고
    • Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in maternal nutrient restricted baboons
    • Pantham, P., Rosario, F.J., Weintraub, S.T., et al. Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in maternal nutrient restricted baboons. Biol Reprod, 95, 2016, 98.
    • (2016) Biol Reprod , vol.95 , pp. 98
    • Pantham, P.1    Rosario, F.J.2    Weintraub, S.T.3
  • 113
    • 84943184461 scopus 로고    scopus 로고
    • Reduced placental amino acid transport in response to maternal nutrient restriction in the baboon
    • Pantham, P., Rosario, F.J., Nijland, M., et al. Reduced placental amino acid transport in response to maternal nutrient restriction in the baboon. Am J Physiol Regul Integr Comp Physiol 309:7 (2015), R740–R746.
    • (2015) Am J Physiol Regul Integr Comp Physiol , vol.309 , Issue.7 , pp. R740-R746
    • Pantham, P.1    Rosario, F.J.2    Nijland, M.3
  • 114
    • 84990879009 scopus 로고    scopus 로고
    • Maternal calorie restriction causing utero-placental insufficiency differentially affects mammalian placental glucose and leucine transport molecular mechanisms
    • en.2016–1259
    • Ganguly, A., Touma, M., Thamotharan, S., De Vivo, D.C., Devaskar, S.U., Maternal calorie restriction causing utero-placental insufficiency differentially affects mammalian placental glucose and leucine transport molecular mechanisms. Endocrinology 157 (2016), 4041–4054 en.2016–1259.
    • (2016) Endocrinology , vol.157 , pp. 4041-4054
    • Ganguly, A.1    Touma, M.2    Thamotharan, S.3    De Vivo, D.C.4    Devaskar, S.U.5
  • 115
    • 0031957538 scopus 로고    scopus 로고
    • Maternal dietary protein deficiency decreases amino acid concentrations in fetal plasma and allantoic fluid of pigs
    • Wu, G., Pond, W.G., Ott, T., Bazer, F.W., Maternal dietary protein deficiency decreases amino acid concentrations in fetal plasma and allantoic fluid of pigs. J Nutr 128:5 (1998), 894–902.
    • (1998) J Nutr , vol.128 , Issue.5 , pp. 894-902
    • Wu, G.1    Pond, W.G.2    Ott, T.3    Bazer, F.W.4
  • 116
    • 84860909945 scopus 로고    scopus 로고
    • Evidence of endoplasmic reticulum stress and protein synthesis inhibition in the placenta of non-native women at high altitude
    • Yung, H.W., Cox, M., Tissot van Patot, M., Burton, G.J., Evidence of endoplasmic reticulum stress and protein synthesis inhibition in the placenta of non-native women at high altitude. FASEB J 26:5 (2012), 1970–1981.
    • (2012) FASEB J , vol.26 , Issue.5 , pp. 1970-1981
    • Yung, H.W.1    Cox, M.2    Tissot van Patot, M.3    Burton, G.J.4
  • 117
    • 84959299504 scopus 로고    scopus 로고
    • Morphological and molecular changes in the murine placenta exposed to normobaric hypoxia throughout pregnancy
    • Matheson, H., Veerbeek, J.H., Charnock-Jones, D.S., Burton, G.J., Yung, H.W., Morphological and molecular changes in the murine placenta exposed to normobaric hypoxia throughout pregnancy. J Physiol 594:5 (2016), 1371–1388.
    • (2016) J Physiol , vol.594 , Issue.5 , pp. 1371-1388
    • Matheson, H.1    Veerbeek, J.H.2    Charnock-Jones, D.S.3    Burton, G.J.4    Yung, H.W.5
  • 118
    • 33845444570 scopus 로고    scopus 로고
    • Effect of hyperinsulinemia on amino acid utilization and oxidation independent of glucose metabolism in the ovine fetus
    • Brown, L.D., Hay, W.W. Jr., Effect of hyperinsulinemia on amino acid utilization and oxidation independent of glucose metabolism in the ovine fetus. Am J Physiol Endocrinol Metab 291:6 (2006), E1333–E1340.
    • (2006) Am J Physiol Endocrinol Metab , vol.291 , Issue.6 , pp. E1333-E1340
    • Brown, L.D.1    Hay, W.W.2
  • 119
    • 65649126443 scopus 로고    scopus 로고
    • Effects of chronic hypoglycemia and euglycemic correction on lysine metabolism in fetal sheep
    • Limesand, S.W., Rozance, P.J., Brown, L.D., Hay, W.W. Jr., Effects of chronic hypoglycemia and euglycemic correction on lysine metabolism in fetal sheep. Am J Physiol Endocrinol Metab 296:4 (2009), E879–E887.
    • (2009) Am J Physiol Endocrinol Metab , vol.296 , Issue.4 , pp. E879-E887
    • Limesand, S.W.1    Rozance, P.J.2    Brown, L.D.3    Hay, W.W.4
  • 120
    • 0021853229 scopus 로고
    • The effects of chronic fetal hyperglycemia on substrate uptake by the ovine fetus and conceptus
    • Philipps, A.F., Rosenkrantz, T.S., Porte, P.J., Raye, J.R., The effects of chronic fetal hyperglycemia on substrate uptake by the ovine fetus and conceptus. Pediatr Res 19:7 (1985), 659–666.
    • (1985) Pediatr Res , vol.19 , Issue.7 , pp. 659-666
    • Philipps, A.F.1    Rosenkrantz, T.S.2    Porte, P.J.3    Raye, J.R.4
  • 121
    • 0027144648 scopus 로고
    • Ovine fetal protein metabolism during decreased glucose delivery
    • Milley, J.R., Ovine fetal protein metabolism during decreased glucose delivery. Am J Physiol 265:4 pt 1 (1993), E525–E531.
    • (1993) Am J Physiol , vol.265 , Issue.4 , pp. E525-E531
    • Milley, J.R.1
  • 122
    • 78650338312 scopus 로고    scopus 로고
    • The neglected role of insulin-like growth factors in the maternal circulation regulating fetal growth
    • Sferruzzi-Perri, A.N., Owens, J.A., Pringle, K.G., Roberts, C.T., The neglected role of insulin-like growth factors in the maternal circulation regulating fetal growth. J Physiol 589:pt 1 (2011), 7–20.
    • (2011) J Physiol , vol.589 , pp. 7-20
    • Sferruzzi-Perri, A.N.1    Owens, J.A.2    Pringle, K.G.3    Roberts, C.T.4
  • 123
    • 0141838042 scopus 로고    scopus 로고
    • The insulin-like growth factors and feto-placental growth
    • Fowden, A.L., The insulin-like growth factors and feto-placental growth. Placenta 24:8–9 (2003), 803–812.
    • (2003) Placenta , vol.24 , Issue.8-9 , pp. 803-812
    • Fowden, A.L.1
  • 124
    • 84860762524 scopus 로고    scopus 로고
    • Maternal and fetal IGF-I and IGF-II levels, fetal growth, and gestational diabetes
    • Luo, Z.C., Nuyt, A.M., Delvin, E., et al. Maternal and fetal IGF-I and IGF-II levels, fetal growth, and gestational diabetes. J Clin Endocrinol Metab 97:5 (2012), 1720–1728.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.5 , pp. 1720-1728
    • Luo, Z.C.1    Nuyt, A.M.2    Delvin, E.3
  • 125
    • 33745157930 scopus 로고    scopus 로고
    • Maternal insulin-like growth factors-I and -II act via different pathways to promote fetal growth
    • Sferruzzi-Perri, A.N., Owens, J., Pringle, K.G., Robinson, J.S., Roberts, C., Maternal insulin-like growth factors-I and -II act via different pathways to promote fetal growth. Endocrinology 147:7 (2006), 3344–3355.
    • (2006) Endocrinology , vol.147 , Issue.7 , pp. 3344-3355
    • Sferruzzi-Perri, A.N.1    Owens, J.2    Pringle, K.G.3    Robinson, J.S.4    Roberts, C.5
  • 126
    • 0027423419 scopus 로고
    • Role of insulin-like growth factors in embryonic and postnatal growth
    • Baker, J., Liu, J.P., Robertson, E.J., Efstratiadis, A., Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75:1 (1993), 73–82.
    • (1993) Cell , vol.75 , Issue.1 , pp. 73-82
    • Baker, J.1    Liu, J.P.2    Robertson, E.J.3    Efstratiadis, A.4
  • 127
    • 0032894853 scopus 로고    scopus 로고
    • Insulin-like growth factor-2 regulation of conceptus composition: effects of the trophectoderm and inner cell mass genotypes in the mouse
    • Gardner, R.L., Squire, S., Zaina, S., Hills, S., Graham, C.F., Insulin-like growth factor-2 regulation of conceptus composition: effects of the trophectoderm and inner cell mass genotypes in the mouse. Biol Reprod 60:1 (1999), 190–195.
    • (1999) Biol Reprod , vol.60 , Issue.1 , pp. 190-195
    • Gardner, R.L.1    Squire, S.2    Zaina, S.3    Hills, S.4    Graham, C.F.5
  • 128
    • 0025320906 scopus 로고
    • A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting
    • DeChiara, T.M., Efstratiadis, A., Robertsen, E.J., A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 345:6270 (1990), 78–80.
    • (1990) Nature , vol.345 , Issue.6270 , pp. 78-80
    • DeChiara, T.M.1    Efstratiadis, A.2    Robertsen, E.J.3
  • 129
    • 0027496895 scopus 로고
    • Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
    • Liu, J.-P., Baker, J., Perkins, A.S., Robertson, E.J., Efstratiadis, A., Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75:1 (1993), 59–72.
    • (1993) Cell , vol.75 , Issue.1 , pp. 59-72
    • Liu, J.-P.1    Baker, J.2    Perkins, A.S.3    Robertson, E.J.4    Efstratiadis, A.5
  • 130
    • 0028851626 scopus 로고
    • Insulin-like growth factor-1 stimulates amino acid uptake by the cultured human placental trophoblast
    • Karl, P.I., Insulin-like growth factor-1 stimulates amino acid uptake by the cultured human placental trophoblast. J Cell Physiol 165:1 (1995), 83–88.
    • (1995) J Cell Physiol , vol.165 , Issue.1 , pp. 83-88
    • Karl, P.I.1
  • 131
    • 84883336433 scopus 로고    scopus 로고
    • Adenoviral-mediated placental gene transfer of IGF-1 corrects placental insufficiency via enhanced placental glucose transport mechanisms
    • Jones, H.N., Crombleholme, T., Habli, M., Adenoviral-mediated placental gene transfer of IGF-1 corrects placental insufficiency via enhanced placental glucose transport mechanisms. PLoS One, 8(9), 2013, e74632.
    • (2013) PLoS One , vol.8 , Issue.9
    • Jones, H.N.1    Crombleholme, T.2    Habli, M.3
  • 132
    • 34447627599 scopus 로고    scopus 로고
    • Early pregnancy maternal endocrine insulin-like growth factor I programs the placenta for increased functional capacity throughout gestation
    • Sferruzzi-Perri, A.N., Owens, J.A., Standen, P., Taylor, R.L., Robinson, J.S., Roberts, C.T., Early pregnancy maternal endocrine insulin-like growth factor I programs the placenta for increased functional capacity throughout gestation. Endocrinology 148:9 (2007), 4362–4370.
    • (2007) Endocrinology , vol.148 , Issue.9 , pp. 4362-4370
    • Sferruzzi-Perri, A.N.1    Owens, J.A.2    Standen, P.3    Taylor, R.L.4    Robinson, J.S.5    Roberts, C.T.6
  • 133
    • 0032869056 scopus 로고    scopus 로고
    • Placental anionic and cationic amino acid transporter expression in growth hormone overexpressing and null IGF-II or null IGF-I receptor mice
    • Matthews, J.C., Beveridge, M.J., Dialynas, E., Bartke, A., Kilberg, M.S., Novak, D.A., Placental anionic and cationic amino acid transporter expression in growth hormone overexpressing and null IGF-II or null IGF-I receptor mice. Placenta 20:8 (1999), 639–650.
    • (1999) Placenta , vol.20 , Issue.8 , pp. 639-650
    • Matthews, J.C.1    Beveridge, M.J.2    Dialynas, E.3    Bartke, A.4    Kilberg, M.S.5    Novak, D.A.6
  • 134
    • 0023105976 scopus 로고
    • Effects of streptozotocin-induced diabetes in pregnant rats on placental transport and tissue uptake of alpha-amino-isobutyric acid
    • Copeland, A.D. Jr., Porterfield, S.P., Effects of streptozotocin-induced diabetes in pregnant rats on placental transport and tissue uptake of alpha-amino-isobutyric acid. Horm Metab Res 19:2 (1987), 57–61.
    • (1987) Horm Metab Res , vol.19 , Issue.2 , pp. 57-61
    • Copeland, A.D.1    Porterfield, S.P.2
  • 135
    • 0022540343 scopus 로고
    • Effects of pancreatectomy on the growth and metabolite concentrations of the sheep fetus
    • Fowden, A.L., Mao, X.Z., Comline, R.S., Effects of pancreatectomy on the growth and metabolite concentrations of the sheep fetus. J Endocrinol 110:2 (1986), 225–231.
    • (1986) J Endocrinol , vol.110 , Issue.2 , pp. 225-231
    • Fowden, A.L.1    Mao, X.Z.2    Comline, R.S.3
  • 136
    • 0028354746 scopus 로고
    • Effects of insulin on ovine fetal leucine kinetics and protein metabolism
    • Milley, J.R., Effects of insulin on ovine fetal leucine kinetics and protein metabolism. J Clin Invest 93:4 (1994), 1616–1624.
    • (1994) J Clin Invest , vol.93 , Issue.4 , pp. 1616-1624
    • Milley, J.R.1
  • 137
    • 33947282207 scopus 로고    scopus 로고
    • Early treatment of the pregnant guinea pig with IGFs promotes placental transport and nutrient partitioning near term
    • Sferruzzi-Perri, A.N., Owens, J.A., Standen, P., et al. Early treatment of the pregnant guinea pig with IGFs promotes placental transport and nutrient partitioning near term. Am J Physiol Endocrinol Metab 292:3 (2007), E668–E676.
    • (2007) Am J Physiol Endocrinol Metab , vol.292 , Issue.3 , pp. E668-E676
    • Sferruzzi-Perri, A.N.1    Owens, J.A.2    Standen, P.3
  • 138
    • 30044432595 scopus 로고    scopus 로고
    • Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems
    • Constancia, M., Angiolini, E., Sandovici, I., et al. Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems. Proc Natl Acad Sci USA 102:52 (2005), 19219–19224.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.52 , pp. 19219-19224
    • Constancia, M.1    Angiolini, E.2    Sandovici, I.3
  • 139
    • 0037182866 scopus 로고    scopus 로고
    • Placental-specific IGF-II is a major modulator of placental and fetal growth
    • Constancia, M., Hemberger, M., Hughes, J., et al. Placental-specific IGF-II is a major modulator of placental and fetal growth. Nature 417:6892 (2002), 945–948.
    • (2002) Nature , vol.417 , Issue.6892 , pp. 945-948
    • Constancia, M.1    Hemberger, M.2    Hughes, J.3
  • 140
    • 80555131204 scopus 로고    scopus 로고
    • System A activity and vascular function in the placental-specific Igf2 knockout mouse
    • Kusinski, L.C., Dilworth, M.R., Baker, P.N., Sibley, C.P., Wareing, M., Glazier, J.D., System A activity and vascular function in the placental-specific Igf2 knockout mouse. Placenta 32:11 (2011), 871–876.
    • (2011) Placenta , vol.32 , Issue.11 , pp. 871-876
    • Kusinski, L.C.1    Dilworth, M.R.2    Baker, P.N.3    Sibley, C.P.4    Wareing, M.5    Glazier, J.D.6
  • 141
    • 79955669396 scopus 로고    scopus 로고
    • Developmental adaptations to increased fetal nutrient demand in mouse genetic models of Igf2-mediated overgrowth
    • Angiolini, E., Coan, P.M., Sandovici, I., et al. Developmental adaptations to increased fetal nutrient demand in mouse genetic models of Igf2-mediated overgrowth. FASEB J 25:5 (2011), 1737–1745.
    • (2011) FASEB J , vol.25 , Issue.5 , pp. 1737-1745
    • Angiolini, E.1    Coan, P.M.2    Sandovici, I.3
  • 142
    • 51849087725 scopus 로고    scopus 로고
    • Adaptations in placental nutrient transfer capacity to meet fetal growth demands depend on placental size in mice
    • Coan, P.M., Angiolini, E., Sandovici, I., Burton, G.J., Constancia, M., Fowden, A.L., Adaptations in placental nutrient transfer capacity to meet fetal growth demands depend on placental size in mice. J Physiol 586:pt 18 (2008), 4567–4576.
    • (2008) J Physiol , vol.586 , pp. 4567-4576
    • Coan, P.M.1    Angiolini, E.2    Sandovici, I.3    Burton, G.J.4    Constancia, M.5    Fowden, A.L.6
  • 143
    • 84989839996 scopus 로고    scopus 로고
    • Maternal and fetal genomes interplay through phosphoinositol 3-kinase(PI3K)-p110α signalling to modify placental resource allocation
    • Sferruzzi-Perri, A., Lopez-Tello, J., Fowden, A., Constancia, M., Maternal and fetal genomes interplay through phosphoinositol 3-kinase(PI3K)-p110α signalling to modify placental resource allocation. Proc Natl Acad Sci USA 113 (2016), 11255–11260.
    • (2016) Proc Natl Acad Sci USA , vol.113 , pp. 11255-11260
    • Sferruzzi-Perri, A.1    Lopez-Tello, J.2    Fowden, A.3    Constancia, M.4
  • 145
    • 77957091736 scopus 로고    scopus 로고
    • The role of adipocytokines in fetal growth
    • Briana, D.D., Malamitsi-Puchner, A., The role of adipocytokines in fetal growth. Ann N Y Acad Sci 1205 (2010), 82–87.
    • (2010) Ann N Y Acad Sci , vol.1205 , pp. 82-87
    • Briana, D.D.1    Malamitsi-Puchner, A.2
  • 146
    • 84903769477 scopus 로고    scopus 로고
    • Increasing maternal body mass index is associated with systemic inflammation in the mother and the activation of distinct placental inflammatory pathways
    • Aye, I.L., Lager, S., Ramirez, V.I., et al. Increasing maternal body mass index is associated with systemic inflammation in the mother and the activation of distinct placental inflammatory pathways. Biol Reprod, 90(6), 2014, 129.
    • (2014) Biol Reprod , vol.90 , Issue.6 , pp. 129
    • Aye, I.L.1    Lager, S.2    Ramirez, V.I.3
  • 147
    • 40649100721 scopus 로고    scopus 로고
    • Obesity in pregnancy stimulates macrophage accumulation and inflammation in the placenta
    • Challier, J.C., Basu, S., Bintein, T., et al. Obesity in pregnancy stimulates macrophage accumulation and inflammation in the placenta. Placenta 29:3 (2008), 274–281.
    • (2008) Placenta , vol.29 , Issue.3 , pp. 274-281
    • Challier, J.C.1    Basu, S.2    Bintein, T.3
  • 148
    • 84884211540 scopus 로고    scopus 로고
    • Review: adiponectin—the missing link between maternal adiposity, placental transport and fetal growth?
    • Aye, I.L., Powell, T.L., Jansson, T., Review: adiponectin—the missing link between maternal adiposity, placental transport and fetal growth?. Placenta 34:suppl (2013), S40–S45.
    • (2013) Placenta , vol.34 , pp. S40-S45
    • Aye, I.L.1    Powell, T.L.2    Jansson, T.3
  • 149
    • 6344233964 scopus 로고    scopus 로고
    • Plasma adiponectin levels in newborns are higher than those in adults and positively correlated with birth weight
    • Kotani, Y., Yokota, I., Kitamura, S., Matsuda, J., Naito, E., Kuroda, Y., Plasma adiponectin levels in newborns are higher than those in adults and positively correlated with birth weight. Clin Endocrinol (Oxf) 61:4 (2004), 418–423.
    • (2004) Clin Endocrinol (Oxf) , vol.61 , Issue.4 , pp. 418-423
    • Kotani, Y.1    Yokota, I.2    Kitamura, S.3    Matsuda, J.4    Naito, E.5    Kuroda, Y.6
  • 150
    • 3242686791 scopus 로고    scopus 로고
    • Cord plasma concentrations of adiponectin and leptin in healthy term neonates: positive correlation with birthweight and neonatal adiposity
    • Tsai, P.J., Yu, C.H., Hsu, S.P., et al. Cord plasma concentrations of adiponectin and leptin in healthy term neonates: positive correlation with birthweight and neonatal adiposity. Clin Endocrinol (Oxf) 61:1 (2004), 88–93.
    • (2004) Clin Endocrinol (Oxf) , vol.61 , Issue.1 , pp. 88-93
    • Tsai, P.J.1    Yu, C.H.2    Hsu, S.P.3
  • 151
    • 42949157703 scopus 로고    scopus 로고
    • Role of leptin in the regulation of growth and carbohydrate metabolism in the ovine fetus during late gestation
    • Forhead, A.J., Lamb, C.A., Franko, K.L., et al. Role of leptin in the regulation of growth and carbohydrate metabolism in the ovine fetus during late gestation. J Physiol 586:9 (2008), 2393–2403.
    • (2008) J Physiol , vol.586 , Issue.9 , pp. 2393-2403
    • Forhead, A.J.1    Lamb, C.A.2    Franko, K.L.3
  • 152
    • 24944536730 scopus 로고    scopus 로고
    • Steroid hormone levels in pregnancy and 1 year postpartum using isotope dilution tandem mass spectrometry
    • Soldin, O.P., Guo, T., Weiderpass, E., Tractenberg, R.E., Hilakivi-Clarke, L., Soldin, S.J., Steroid hormone levels in pregnancy and 1 year postpartum using isotope dilution tandem mass spectrometry. Fertil Steril 84:3 (2005), 701–710.
    • (2005) Fertil Steril , vol.84 , Issue.3 , pp. 701-710
    • Soldin, O.P.1    Guo, T.2    Weiderpass, E.3    Tractenberg, R.E.4    Hilakivi-Clarke, L.5    Soldin, S.J.6
  • 154
    • 0031990135 scopus 로고    scopus 로고
    • Glucocorticoids and the preparation for life after birth: are there long-term consequences of the life insurance?
    • Fowden, A.L., Li, J., Forhead, A.J., Glucocorticoids and the preparation for life after birth: are there long-term consequences of the life insurance?. Proc Nutr Soc 57:1 (1998), 113–122.
    • (1998) Proc Nutr Soc , vol.57 , Issue.1 , pp. 113-122
    • Fowden, A.L.1    Li, J.2    Forhead, A.J.3
  • 155
    • 84856972106 scopus 로고    scopus 로고
    • Placental drug transporters and their role in fetal protection
    • Iqbal, M., Audette, M.C., Petropoulos, S., Gibb, W., Matthews, S.G., Placental drug transporters and their role in fetal protection. Placenta 33:3 (2012), 137–142.
    • (2012) Placenta , vol.33 , Issue.3 , pp. 137-142
    • Iqbal, M.1    Audette, M.C.2    Petropoulos, S.3    Gibb, W.4    Matthews, S.G.5
  • 156
    • 34249316880 scopus 로고    scopus 로고
    • Mechanisms of disease: glucocorticoids, their placental metabolism and fetal ‘programming’ of adult pathophysiology
    • Seckl, J.R., Holmes, M.C., Mechanisms of disease: glucocorticoids, their placental metabolism and fetal ‘programming’ of adult pathophysiology. Nat Clin Pract Endocrinol Metab 3:6 (2007), 479–488.
    • (2007) Nat Clin Pract Endocrinol Metab , vol.3 , Issue.6 , pp. 479-488
    • Seckl, J.R.1    Holmes, M.C.2
  • 157
    • 33747674189 scopus 로고    scopus 로고
    • Maternal testosterone levels during pregnancy are associated with offspring size at birth
    • Carlsen, S.M., Jacobsen, G., Romundstad, P., Maternal testosterone levels during pregnancy are associated with offspring size at birth. Eur J Endocrinol 155:2 (2006), 365–370.
    • (2006) Eur J Endocrinol , vol.155 , Issue.2 , pp. 365-370
    • Carlsen, S.M.1    Jacobsen, G.2    Romundstad, P.3
  • 158
    • 76349100734 scopus 로고    scopus 로고
    • Free testosterone levels in umbilical-cord blood predict infant head circumference in females
    • Whitehouse, A.J., Maybery, M.T., Hart, R., et al. Free testosterone levels in umbilical-cord blood predict infant head circumference in females. Dev Med Child Neurol 52:3 (2010), e73–e77.
    • (2010) Dev Med Child Neurol , vol.52 , Issue.3 , pp. e73-e77
    • Whitehouse, A.J.1    Maybery, M.T.2    Hart, R.3
  • 159
    • 0027367418 scopus 로고
    • Elevated levels of umbilical cord plasma corticotropin-releasing hormone in growth-retarded fetuses
    • Goland, R.S., Jozak, S., Warren, W.B., Conwell, I.M., Stark, R.I., Tropper, P.J., Elevated levels of umbilical cord plasma corticotropin-releasing hormone in growth-retarded fetuses. J Clin Endocrinol Metab 77:5 (1993), 1174–1179.
    • (1993) J Clin Endocrinol Metab , vol.77 , Issue.5 , pp. 1174-1179
    • Goland, R.S.1    Jozak, S.2    Warren, W.B.3    Conwell, I.M.4    Stark, R.I.5    Tropper, P.J.6
  • 160
    • 14644440805 scopus 로고    scopus 로고
    • Cortisol levels in umbilical vein and umbilical artery with or without antenatal corticosteroids
    • Manabe, M., Nishida, T., Imai, T., et al. Cortisol levels in umbilical vein and umbilical artery with or without antenatal corticosteroids. Pediatr Int 47:1 (2005), 60–63.
    • (2005) Pediatr Int , vol.47 , Issue.1 , pp. 60-63
    • Manabe, M.1    Nishida, T.2    Imai, T.3
  • 161
    • 84862777692 scopus 로고    scopus 로고
    • Late gestational maternal serum cortisol is inversely associated with fetal brain growth
    • Li, J., Wang, Z.N., Chen, Y.P., et al. Late gestational maternal serum cortisol is inversely associated with fetal brain growth. Neurosci Biobehav Rev 36:3 (2012), 1085–1092.
    • (2012) Neurosci Biobehav Rev , vol.36 , Issue.3 , pp. 1085-1092
    • Li, J.1    Wang, Z.N.2    Chen, Y.P.3
  • 163
    • 37649028033 scopus 로고    scopus 로고
    • Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth
    • Roberts, D., Dalziel, S., Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev(3), 2006, CD004454.
    • (2006) Cochrane Database Syst Rev , Issue.3
    • Roberts, D.1    Dalziel, S.2
  • 164
    • 84910010683 scopus 로고    scopus 로고
    • Synthetic glucocorticoid reduces human placental system a transport in women treated with antenatal therapy
    • Audette, M.C., Challis, J.R.G., Jones, R.L., Sibley, C.P., Matthews, S.G., Synthetic glucocorticoid reduces human placental system a transport in women treated with antenatal therapy. J Clin Endocrinol Metabol 99:11 (2014), E2226–E2233.
    • (2014) J Clin Endocrinol Metabol , vol.99 , Issue.11 , pp. E2226-E2233
    • Audette, M.C.1    Challis, J.R.G.2    Jones, R.L.3    Sibley, C.P.4    Matthews, S.G.5
  • 165
    • 67649847784 scopus 로고    scopus 로고
    • Altered placental function of 11beta-hydroxysteroid dehydrogenase 2 knockout mice
    • Wyrwoll, C.S., Seckl, J.R., Holmes, M.C., Altered placental function of 11beta-hydroxysteroid dehydrogenase 2 knockout mice. Endocrinology 150:3 (2009), 1287–1293.
    • (2009) Endocrinology , vol.150 , Issue.3 , pp. 1287-1293
    • Wyrwoll, C.S.1    Seckl, J.R.2    Holmes, M.C.3
  • 166
    • 84869094274 scopus 로고    scopus 로고
    • The emerging role of mTORC1 signaling in placental nutrient-sensing
    • Jansson, T., Aye, I.L.M.H., Goberdhan, D.C., The emerging role of mTORC1 signaling in placental nutrient-sensing. Placenta 33:suppl 2 (2012), e23–e29.
    • (2012) Placenta , vol.33 , pp. e23-e29
    • Jansson, T.1    Aye, I.L.M.H.2    Goberdhan, D.C.3
  • 167
    • 58349106216 scopus 로고    scopus 로고
    • Regulation of placental amino acid transporter activity by mammalian target of rapamycin
    • Roos, S., Kanai, Y., Prasad, P.D., Powell, T.L., Jansson, T., Regulation of placental amino acid transporter activity by mammalian target of rapamycin. Am J Physiol Cell Physiol 296:1 (2009), C142–C150.
    • (2009) Am J Physiol Cell Physiol , vol.296 , Issue.1 , pp. C142-C150
    • Roos, S.1    Kanai, Y.2    Prasad, P.D.3    Powell, T.L.4    Jansson, T.5
  • 168
    • 84873156962 scopus 로고    scopus 로고
    • Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells
    • Rosario, F.J., Kanai, Y., Powell, T.L., Jansson, T., Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells. J Physiol 591:3 (2013), 609–625.
    • (2013) J Physiol , vol.591 , Issue.3 , pp. 609-625
    • Rosario, F.J.1    Kanai, Y.2    Powell, T.L.3    Jansson, T.4
  • 169
    • 84959517849 scopus 로고    scopus 로고
    • Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2
    • Rosario Fredrick, J., Dimasuay Kris, G., Kanai, Y., Powell Theresa, L., Jansson, T., Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2. Clin Sci 130:7 (2016), 499–512.
    • (2016) Clin Sci , vol.130 , Issue.7 , pp. 499-512
    • Rosario Fredrick, J.1    Dimasuay Kris, G.2    Kanai, Y.3    Powell Theresa, L.4    Jansson, T.5
  • 170
    • 34347211057 scopus 로고    scopus 로고
    • Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth
    • Roos, S., Jansson, N., Palmberg, I., Saljo, K., Powell, T.L., Jansson, T., Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth. J Physiol 582:pt 1 (2007), 449–459.
    • (2007) J Physiol , vol.582 , pp. 449-459
    • Roos, S.1    Jansson, N.2    Palmberg, I.3    Saljo, K.4    Powell, T.L.5    Jansson, T.6
  • 171
    • 84952050095 scopus 로고    scopus 로고
    • Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR
    • Chen, Y.-Y., Rosario Fredrick, J., Shehab Majida, A., Powell Theresa, L., Gupta Madhulika, B., Jansson, T., Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR. Clin Sci 129:12 (2015), 1131–1141.
    • (2015) Clin Sci , vol.129 , Issue.12 , pp. 1131-1141
    • Chen, Y.-Y.1    Rosario Fredrick, J.2    Shehab Majida, A.3    Powell Theresa, L.4    Gupta Madhulika, B.5    Jansson, T.6
  • 172
    • 84908020928 scopus 로고    scopus 로고
    • Diet-induced obesity in mice reduces placental efficiency and inhibits placental mTOR signaling
    • Lager, S., Samulesson, A.M., Taylor, P.D., Poston, L., Powell, T.L., Jansson, T., Diet-induced obesity in mice reduces placental efficiency and inhibits placental mTOR signaling. Physiol Rep, 2(2), 2014, e00242.
    • (2014) Physiol Rep , vol.2 , Issue.2 , pp. e00242
    • Lager, S.1    Samulesson, A.M.2    Taylor, P.D.3    Poston, L.4    Powell, T.L.5    Jansson, T.6
  • 173
    • 84355166527 scopus 로고    scopus 로고
    • Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo
    • Gonzalez, I.M., Martin, P.M., Burdsal, C., et al. Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo. Dev Biol 361:2 (2012), 286–300.
    • (2012) Dev Biol , vol.361 , Issue.2 , pp. 286-300
    • Gonzalez, I.M.1    Martin, P.M.2    Burdsal, C.3
  • 174
    • 84880841362 scopus 로고    scopus 로고
    • Arginine, leucine, and glutamine stimulate proliferation of porcine trophectoderm cells through the MTOR-RPS6K-RPS6-EIF4EBP1 signal transduction pathway
    • 111–119
    • Kim, J., Song, G., Wu, G., Gao, H., Johnson, G.A., Bazer, F.W., Arginine, leucine, and glutamine stimulate proliferation of porcine trophectoderm cells through the MTOR-RPS6K-RPS6-EIF4EBP1 signal transduction pathway. Biol Reprod, 88(5), 2013, 113 111–119.
    • (2013) Biol Reprod , vol.88 , Issue.5 , pp. 113
    • Kim, J.1    Song, G.2    Wu, G.3    Gao, H.4    Johnson, G.A.5    Bazer, F.W.6
  • 175
    • 84956594691 scopus 로고    scopus 로고
    • A novel rat model of gestational diabetes induced by intrauterine programming is associated with alterations in placental signaling and fetal overgrowth
    • Capobianco, E., Fornes, D., Linenberg, I., Powell, T.L., Jansson, T., Jawerbaum, A., A novel rat model of gestational diabetes induced by intrauterine programming is associated with alterations in placental signaling and fetal overgrowth. Mol Cell Endocrinol 422 (2016), 221–232.
    • (2016) Mol Cell Endocrinol , vol.422 , pp. 221-232
    • Capobianco, E.1    Fornes, D.2    Linenberg, I.3    Powell, T.L.4    Jansson, T.5    Jawerbaum, A.6
  • 176
    • 84899786094 scopus 로고    scopus 로고
    • Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2alpha signaling and increases fetal growth in rats
    • Gaccioli, F., White, V., Capobianco, E., Powell, T.L., Jawerbaum, A., Jansson, T., Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2alpha signaling and increases fetal growth in rats. Biol Reprod, 89(4), 2013, 96.
    • (2013) Biol Reprod , vol.89 , Issue.4 , pp. 96
    • Gaccioli, F.1    White, V.2    Capobianco, E.3    Powell, T.L.4    Jawerbaum, A.5    Jansson, T.6
  • 177
    • 84989908385 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor-1alpha, regulated in development and DNA damage response-1 and mammalian target of rapamycin in human placental BeWo cells under hypoxia
    • Zhou, F., Guan, L.B., Yu, P., Wang, X.D., Hu, Y.Y., Regulation of hypoxia-inducible factor-1alpha, regulated in development and DNA damage response-1 and mammalian target of rapamycin in human placental BeWo cells under hypoxia. Placenta 45 (2016), 24–31.
    • (2016) Placenta , vol.45 , pp. 24-31
    • Zhou, F.1    Guan, L.B.2    Yu, P.3    Wang, X.D.4    Hu, Y.Y.5
  • 178
    • 84873822689 scopus 로고    scopus 로고
    • Suppression of mitochondrial electron transport chain function in the hypoxic human placenta: a role for miRNA-210 and protein synthesis inhibition
    • Colleoni, F., Padmanabhan, N., Yung, H.W., et al. Suppression of mitochondrial electron transport chain function in the hypoxic human placenta: a role for miRNA-210 and protein synthesis inhibition. PLoS One, 8(1), 2013, e55194.
    • (2013) PLoS One , vol.8 , Issue.1
    • Colleoni, F.1    Padmanabhan, N.2    Yung, H.W.3
  • 179
    • 84959274629 scopus 로고    scopus 로고
    • Hypoxia, AMPK activation and uterine artery vasoreactivity
    • Skeffington, K.L., Higgins, J.S., Mahmoud, A.D., et al. Hypoxia, AMPK activation and uterine artery vasoreactivity. J Physiol 594 (2016), 1357–1369.
    • (2016) J Physiol , vol.594 , pp. 1357-1369
    • Skeffington, K.L.1    Higgins, J.S.2    Mahmoud, A.D.3
  • 180
    • 33646383684 scopus 로고    scopus 로고
    • A pharmacological map of the PI3-K family defines a role for p110α in insulin signaling
    • Knight, Z.A., Gonzalez, B., Feldman, M.E., et al. A pharmacological map of the PI3-K family defines a role for p110α in insulin signaling. Cell 125:4 (2006), 733–747.
    • (2006) Cell , vol.125 , Issue.4 , pp. 733-747
    • Knight, Z.A.1    Gonzalez, B.2    Feldman, M.E.3
  • 181
    • 78751512142 scopus 로고    scopus 로고
    • Impairment of insulin receptor signal transduction in placentas of intra-uterine growth-restricted newborns and its relationship with fetal growth
    • Street, M.E., Viani, I., Ziveri, M.A., Volta, C., Smerieri, A., Bernasconi, S., Impairment of insulin receptor signal transduction in placentas of intra-uterine growth-restricted newborns and its relationship with fetal growth. Eur J Endocrinol 164:1 (2011), 45–52.
    • (2011) Eur J Endocrinol , vol.164 , Issue.1 , pp. 45-52
    • Street, M.E.1    Viani, I.2    Ziveri, M.A.3    Volta, C.4    Smerieri, A.5    Bernasconi, S.6
  • 182
    • 20044376471 scopus 로고    scopus 로고
    • Intrauterine growth restriction in humans is associated with abnormalities in placental insulin-like growth factor signaling
    • Laviola, L., Perrini, S., Belsanti, G., et al. Intrauterine growth restriction in humans is associated with abnormalities in placental insulin-like growth factor signaling. Endocrinology 146:3 (2005), 1498–1505.
    • (2005) Endocrinology , vol.146 , Issue.3 , pp. 1498-1505
    • Laviola, L.1    Perrini, S.2    Belsanti, G.3
  • 183
    • 33750478017 scopus 로고    scopus 로고
    • Effects of gestational diabetes mellitus on proteins implicated in insulin signaling in human placenta
    • Alonso, A., Del Rey, C.G., Navarro, A., Tolivia, J., Gonzalez, C.G., Effects of gestational diabetes mellitus on proteins implicated in insulin signaling in human placenta. Gynecol Endocrinol 22:9 (2006), 526–535.
    • (2006) Gynecol Endocrinol , vol.22 , Issue.9 , pp. 526-535
    • Alonso, A.1    Del Rey, C.G.2    Navarro, A.3    Tolivia, J.4    Gonzalez, C.G.5
  • 184
    • 84878582344 scopus 로고    scopus 로고
    • Activated translation signaling in placenta from pregnant women with gestational diabetes mellitus: possible role of leptin
    • Perez-Perez, A., Maymo, J.L., Gambino, Y.P., et al. Activated translation signaling in placenta from pregnant women with gestational diabetes mellitus: possible role of leptin. Horm Metab Res 45:6 (2013), 436–442.
    • (2013) Horm Metab Res , vol.45 , Issue.6 , pp. 436-442
    • Perez-Perez, A.1    Maymo, J.L.2    Gambino, Y.P.3
  • 185
    • 84956964471 scopus 로고    scopus 로고
    • Activation of placental insulin and mTOR signaling in a mouse model of maternal obesity associated with fetal overgrowth
    • Rosario, F.J., Powell, T.L., Jansson, T., Activation of placental insulin and mTOR signaling in a mouse model of maternal obesity associated with fetal overgrowth. Am J Physiol Regul Integr Comp Physiol 310:1 (2016), R87–R93.
    • (2016) Am J Physiol Regul Integr Comp Physiol , vol.310 , Issue.1 , pp. R87-R93
    • Rosario, F.J.1    Powell, T.L.2    Jansson, T.3
  • 186
    • 77953289537 scopus 로고    scopus 로고
    • MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells
    • Perez-Perez, A., Gambino, Y., Maymo, J., et al. MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells. Biochem Biophys Res Commun 396:4 (2010), 956–960.
    • (2010) Biochem Biophys Res Commun , vol.396 , Issue.4 , pp. 956-960
    • Perez-Perez, A.1    Gambino, Y.2    Maymo, J.3
  • 187
    • 84897953737 scopus 로고    scopus 로고
    • Adiponectin inhibits insulin function in primary trophoblasts by PPARα-mediated ceramide synthesis
    • Aye, I.L.M.H., Gao, X., Weintraub, S.T., Jansson, T., Powell, T.L., Adiponectin inhibits insulin function in primary trophoblasts by PPARα-mediated ceramide synthesis. Mol Endocrinol 28:4 (2014), 512–524.
    • (2014) Mol Endocrinol , vol.28 , Issue.4 , pp. 512-524
    • Aye, I.L.M.H.1    Gao, X.2    Weintraub, S.T.3    Jansson, T.4    Powell, T.L.5
  • 188
    • 70449348176 scopus 로고    scopus 로고
    • Mechanisms generating diversity in glucocorticoid receptor signaling
    • Revollo, J.R., Cidlowski, J.A., Mechanisms generating diversity in glucocorticoid receptor signaling. Ann N Y Acad Sci 1179 (2009), 167–178.
    • (2009) Ann N Y Acad Sci , vol.1179 , pp. 167-178
    • Revollo, J.R.1    Cidlowski, J.A.2
  • 189
    • 84960158675 scopus 로고    scopus 로고
    • Glucocorticoid-induced fetal origins of adult hypertension: association with epigenetic events
    • Anwar, M.A., Saleh, A.I., Al Olabi, R., Al Shehabi, T.S., Eid, A.H., Glucocorticoid-induced fetal origins of adult hypertension: association with epigenetic events. Vascul Pharmacol 82 (2016), 41–50.
    • (2016) Vascul Pharmacol , vol.82 , pp. 41-50
    • Anwar, M.A.1    Saleh, A.I.2    Al Olabi, R.3    Al Shehabi, T.S.4    Eid, A.H.5
  • 190
    • 0038777070 scopus 로고    scopus 로고
    • Properties and regulation of glutamine transporter SN1 by protein kinases SGK and PKB
    • Boehmer, C., Okur, F., Setiawan, I., Broer, S., Lang, F., Properties and regulation of glutamine transporter SN1 by protein kinases SGK and PKB. Biochem Biophys Res Commun 306:1 (2003), 156–162.
    • (2003) Biochem Biophys Res Commun , vol.306 , Issue.1 , pp. 156-162
    • Boehmer, C.1    Okur, F.2    Setiawan, I.3    Broer, S.4    Lang, F.5
  • 191
    • 84923455613 scopus 로고    scopus 로고
    • Corticosterone alters materno-fetal glucose partitioning and insulin signalling in pregnant mice
    • Vaughan, O.R., Fisher, H.M., Dionelis, K.N., et al. Corticosterone alters materno-fetal glucose partitioning and insulin signalling in pregnant mice. J Physiol 593:5 (2015), 1307–1321.
    • (2015) J Physiol , vol.593 , Issue.5 , pp. 1307-1321
    • Vaughan, O.R.1    Fisher, H.M.2    Dionelis, K.N.3
  • 192
    • 84928313733 scopus 로고    scopus 로고
    • Dexamethasone treatment of pregnant F0 mice leads to parent of origin-specific changes in placental function of the F2 generation
    • Vaughan, O.R., Phillips, H.M., Everden, A.J., Sferruzzi-Perri, A.N., Fowden, A.L., Dexamethasone treatment of pregnant F0 mice leads to parent of origin-specific changes in placental function of the F2 generation. Reprod Fertil Dev 27:4 (2015), 704–711.
    • (2015) Reprod Fertil Dev , vol.27 , Issue.4 , pp. 704-711
    • Vaughan, O.R.1    Phillips, H.M.2    Everden, A.J.3    Sferruzzi-Perri, A.N.4    Fowden, A.L.5
  • 193
    • 84994030767 scopus 로고    scopus 로고
    • A physiological increase in maternal cortisol alters uteroplacental metabolism in the pregnant ewe
    • Vaughan, O.R., Davies, K.L., Ward, J.W., de Blasio, M.J., Fowden, A.L., A physiological increase in maternal cortisol alters uteroplacental metabolism in the pregnant ewe. J Physiol 594 (2016), 6407–6418.
    • (2016) J Physiol , vol.594 , pp. 6407-6418
    • Vaughan, O.R.1    Davies, K.L.2    Ward, J.W.3    de Blasio, M.J.4    Fowden, A.L.5
  • 194
    • 84957112025 scopus 로고    scopus 로고
    • Maternal factors are associated with the expression of placental genes involved in amino acid metabolism and transport
    • Day, P.E., Ntani, G., Crozier, S.R., et al. Maternal factors are associated with the expression of placental genes involved in amino acid metabolism and transport. PLoS One, 10(12), 2015, e0143653.
    • (2015) PLoS One , vol.10 , Issue.12
    • Day, P.E.1    Ntani, G.2    Crozier, S.R.3
  • 195
    • 84936891480 scopus 로고    scopus 로고
    • Placental amino acid transport may be regulated by maternal vitamin D and vitamin D-binding protein: results from the Southampton Women's Survey
    • Cleal, J.K., Day, P.E., Simner, C.L., et al. Placental amino acid transport may be regulated by maternal vitamin D and vitamin D-binding protein: results from the Southampton Women's Survey. Br J Nutr 113:12 (2015), 1903–1910.
    • (2015) Br J Nutr , vol.113 , Issue.12 , pp. 1903-1910
    • Cleal, J.K.1    Day, P.E.2    Simner, C.L.3
  • 196
    • 0036737370 scopus 로고    scopus 로고
    • The effect of a maternal infusion of amino acids on umbilical uptake in pregnancies complicated by intrauterine growth restriction
    • Ronzoni, S., Marconi, A.M., Paolini, C.L., Teng, C., Pardi, G., Battaglia, F.C., The effect of a maternal infusion of amino acids on umbilical uptake in pregnancies complicated by intrauterine growth restriction. Am J Obstet Gynecol 187:3 (2002), 741–746.
    • (2002) Am J Obstet Gynecol , vol.187 , Issue.3 , pp. 741-746
    • Ronzoni, S.1    Marconi, A.M.2    Paolini, C.L.3    Teng, C.4    Pardi, G.5    Battaglia, F.C.6
  • 197
    • 84864504890 scopus 로고    scopus 로고
    • Acute supplementation of amino acids increases net protein accretion in IUGR fetal sheep
    • Brown, L.D., Rozance, P.J., Thorn, S.R., Friedman, J.E., Hay, W.W. Jr., Acute supplementation of amino acids increases net protein accretion in IUGR fetal sheep. Am J Physiol Endocrinol Metab 303:3 (2012), E352–E364.
    • (2012) Am J Physiol Endocrinol Metab , vol.303 , Issue.3 , pp. E352-E364
    • Brown, L.D.1    Rozance, P.J.2    Thorn, S.R.3    Friedman, J.E.4    Hay, W.W.5
  • 198
    • 84861302630 scopus 로고    scopus 로고
    • Weekly intra-amniotic IGF-1 treatment increases growth of growth-restricted ovine fetuses and up-regulates placental amino acid transporters
    • Wali, J.A., de Boo, H.A., Derraik, J.G., et al. Weekly intra-amniotic IGF-1 treatment increases growth of growth-restricted ovine fetuses and up-regulates placental amino acid transporters. PLoS One, 7(5), 2012, e37899.
    • (2012) PLoS One , vol.7 , Issue.5
    • Wali, J.A.1    de Boo, H.A.2    Derraik, J.G.3
  • 199
    • 84893760582 scopus 로고    scopus 로고
    • Regulation of amino acid transporters by adenoviral-mediated human insulin-like growth factor-1 in a mouse model of placental insufficiency in vivo and the human trophoblast line BeWo in vitro
    • Jones, H., Crombleholme, T., Habli, M., Regulation of amino acid transporters by adenoviral-mediated human insulin-like growth factor-1 in a mouse model of placental insufficiency in vivo and the human trophoblast line BeWo in vitro. Placenta 35:2 (2014), 132–138.
    • (2014) Placenta , vol.35 , Issue.2 , pp. 132-138
    • Jones, H.1    Crombleholme, T.2    Habli, M.3
  • 200
    • 84949545651 scopus 로고    scopus 로고
    • The impact of a human IGF-II analog ([Leu27]IGF-II) on fetal growth in a mouse model of fetal growth restriction
    • Charnock, J.C., Dilworth, M.R., Aplin, J.D., Sibley, C.P., Westwood, M., Crocker, I.P., The impact of a human IGF-II analog ([Leu27]IGF-II) on fetal growth in a mouse model of fetal growth restriction. Am J Physiol Endocrinol Metab 310:1 (2016), E24–E31.
    • (2016) Am J Physiol Endocrinol Metab , vol.310 , Issue.1 , pp. E24-E31
    • Charnock, J.C.1    Dilworth, M.R.2    Aplin, J.D.3    Sibley, C.P.4    Westwood, M.5    Crocker, I.P.6


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