Interleukin-1β inhibits insulin signaling and prevents insulin-stimulated system A amino acid transport in primary human trophoblasts

Molecular and Cellular Endocrinology

Volumn 381, Issue 1-2, 2013, Pages 46-55

  Aye, Irving L M H ^a   Jansson, Thomas ^a   Powell, Theresa L ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Inflammation; Insulin resistance; Maternal fetal exchange; Placenta

Indexed keywords

AMINO ACID; AMINO ACID TRANSPORTER; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR BETA; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P85; RAF PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

AMINO ACID TRANSPORT; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INSULIN RESISTANCE; PLACENTA; PREGNANT WOMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TROPHOBLAST; WESTERN BLOTTING;

INFLAMMATION; INSULIN-RESISTANCE; MATERNAL-FETAL EXCHANGE; PLACENTA;

AMINO ACID TRANSPORT SYSTEM A; AMINO ACID TRANSPORT SYSTEM L; AMINO ACIDS; BIOLOGICAL TRANSPORT; CELLS, CULTURED; ENZYME ACTIVATION; FEMALE; GRB2 ADAPTOR PROTEIN; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; METABOLIC NETWORKS AND PATHWAYS; NF-KAPPA B; PHOSPHORYLATION; PRIMARY CELL CULTURE; PROTEIN PROCESSING, POST-TRANSLATIONAL; TROPHOBLASTS;

EID: 84882751390     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.07.013     Document Type: Article

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