Integration of computational modeling with membrane transport studies reveals new insights into amino acid exchange transport mechanisms

FASEB Journal

Volumn 29, Issue 6, 2015, Pages 2583-2594

  Widdows, Kate L ^a   Panitchob, Nuttanont ^b   Crocker, Ian P ^a   Please, Colin P ^c   Hanson, Mark A ^d   Sibley, Colin P ^a   Johnstone, Edward D ^a   Sengers, Bram G ^b   Lewis, Rohan M ^b,d   Glazier, Jocelyn D ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Antiporters; Facilitated transport; LAT2 (SLC7A8); Overshoot phenomena

Indexed keywords

AMINO ACID TRANSPORTER; ANTIPORTER; SERINE; AMINO ACID; CARBON; CD98 ANTIGEN; SLC7A8 PROTEIN, HUMAN;

AMINO ACID TRANSPORT; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MATHEMATICAL MODEL; MEMBRANE TRANSPORT; MEMBRANE VESICLE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SYNCYTIOTROPHOBLAST; BIOLOGICAL MODEL; COMPUTER SIMULATION; CYTOLOGY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; MICROVILLUS; PLACENTA; PREGNANCY; TRANSPORT AT THE CELLULAR LEVEL; TRANSPORT VESICLE; WESTERN BLOTTING;

AMINO ACID TRANSPORT SYSTEM Y+; AMINO ACIDS; ANTIGENS, CD98 LIGHT CHAINS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CARBON RADIOISOTOPES; CELL MEMBRANE; COMPUTER SIMULATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; LARGE NEUTRAL AMINO ACID-TRANSPORTER 1; MICROVILLI; MODELS, BIOLOGICAL; PLACENTA; PREGNANCY; SERINE; TRANSPORT VESICLES;

EID: 84933544622     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-267773     Document Type: Article

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