Maternal and fetal genomes interplay through phosphoinositol 3-kinase(PI3K)-p110α signaling to modify placental resource allocation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 40, 2016, Pages 11255-11260

  Sferruzzi Perri, Amanda N ^a   López Tello, Jorge ^a   Fowden, Abigail L ^a   Constancia, Miguel ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

Fetus; Nutrient transport; PI3K; Placenta; Resource allocation

Indexed keywords

AMINO ACID; GLUCOSE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE P110ALPHA; UNCLASSIFIED DRUG; 1-PHOSPHATIDYLINOSITOL 3-KINASE P110 SUBUNIT, MOUSE; 2,2-DIMETHYL-BETA-ALANINE; 3 METHYLGLUCOSE; BETA ALANINE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENDOCRINE FUNCTION; FEMALE; FETOPLACENTAL UNIT; GENE EXPRESSION; GENE INACTIVATION; GENOME; GENOTYPE; LIVER WEIGHT; MALE; METABOLISM; MOTHER; MOUSE; NONHUMAN; NUTRIENT UPTAKE; PHENOTYPE; PLACENTA; PLACENTA DEVELOPMENT; PLACENTAL TRANSFER; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANATOMY AND HISTOLOGY; ANIMAL; BIOLOGICAL MODEL; CELL LINEAGE; DEFICIENCY; ENDOCRINE SYSTEM; ENZYME ACTIVATION; FETOMATERNAL TRANSFUSION; FETUS; FETUS DEVELOPMENT; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; LIVER; METABOLOMICS; ORGAN SIZE; PREGNANCY; TRANSPORT AT THE CELLULAR LEVEL;

3-O-METHYLGLUCOSE; ANIMALS; BETA-ALANINE; BIOLOGICAL TRANSPORT; BODY WEIGHT; CELL LINEAGE; CLASS I PHOSPHATIDYLINOSITOL 3-KINASES; ENDOCRINE SYSTEM; ENZYME ACTIVATION; FEMALE; FETAL DEVELOPMENT; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOME; LIVER; MATERNAL-FETAL EXCHANGE; METABOLOMICS; MICE, KNOCKOUT; MODELS, BIOLOGICAL; ORGAN SIZE; PLACENTA; PREGNANCY; SIGNAL TRANSDUCTION;

EID: 84989839996     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1602012113     Document Type: Article

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