Association between the activity of the system A amino acid transporter in the microvillous plasma membrane of the human placenta and severity of fetal compromise in intrauterine growth restriction

Pediatric Research

Volumn 42, Issue 4, 1997, Pages 514-519

  Glazier, Jocelyn D ^a   Cetin, Irene ^b,c   Perugino, Giuseppe ^b   Ronzoni, Stefania ^b   Grey, Anne Marie ^a   Mahendran, Dhushyanthan ^a   Marconi, Anna Maria ^b   Pardi, Giorgio ^b   Sibley, Colin P ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN;

ADULT; ARTICLE; CESAREAN SECTION; CLINICAL ARTICLE; ELECTIVE SURGERY; FEMALE; FETUS; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; INTRAUTERINE GROWTH RETARDATION; MICROVILLUS; NEWBORN; PLACENTA VILLUS; PRIORITY JOURNAL; PROTEIN DETERMINATION; THIRD TRIMESTER PREGNANCY;

EID: 0030812757     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199710000-00016     Document Type: Article

References (23)

1. Daffos F, Capella-Pavlowsky M, Forestier F 1985 Fetal blood sampling during pregnancy with use of a needle guided by ultrasound: a study of 606 consecutive cases. Am J Obstet Gynecol 153:655-660
2. Marconi AM, Cetin I, Buscaglia M, Pardi G 1992 Midgestation cord sampling: what have we learned. Placenta 13:115-122
3. Cetin I, Corbetta C, Sereni LP, Marconi AM, Bozzetti P, Pardi G, Battaglia FC 1990 Umbilical amino acid concentrations in normal and growth-retarded fetuses sampled in utero by cordocentesis. Am J Obstet Gynecol 162:253-261
4. Economides DL, Nicolaides KH, Gahl WA, Bernardini I, Evans MI 1989 Plasma amino acids in appropriate and small-for-gestational-age fetuses. Am J Obstet Gynecol 161:1219-1227
5. Pardi G, Cetin I, Marconi AM, Lanfranchi A, Bozzetti P, Ferrazzi E, Buscaglia M, Battaglia FC 1993 Diagnostic value of blood sampling in fetuses with growth retardation. N Engl J Med 328:692-696
6. Morris FH, Boyd RDH, Mahendran D 1994 Placental transport. In: Knobil E and Neill JD (eds) The Physiology of Reproduction. 2nd Ed. Raven Press, New York, pp 813-860
7. Moe A 1995 Placental amino acid transport. Am J Physiol 268:C1321-C1331
8. Dicke JM, Henderson GI 1988 Placental amino acid uptake in normal and complicated pregnancies. Am J Med Sci 295:223-227
9. Mahendran D, Donnai P, Glazier JD, D'Souza SW, Boyd RDH, Sibley CP 1993 Amino acid (system A) transporter activity in microvillous membrane vesicles from the placentas of appropriate and small for gestational age babies. Pediatr Res 34:661-665
10. Sibley CP, D'Souza SW, Doughty I, Boyd RDH, Glazier JD, Kuruvilla A, Mahendran D 1995 Birthweight and sodium/proton exchanger activity in the term human placenta. Placenta 16:469-470
11. Powell TL, Illsley NP 1996 A novel technique for studying cellular function in human placenta: gestational changes in intracellular pH regulation. Placenta 17:661-668
12. Soothill PW, Ajayi RA, Nicolaides KN 1992 Fetal biochemistry in growth retardation. Early Hum Dev 29:91-97
13. Todros T, Ferrazzi E, Groli C, Nicolini U, Parodi L, Pavoni M, Zorzoli A, Zucca S 1987 Fitting growth curves to head and abdomen measurements of the fetus: a multicentric study. J Clin Ultrasound 15:95-105
14. Parazzini F, Cortinovis I, Bortolus R, Fedele L 1991 Standard di peso alla nascita in Italia. Ann Ost Gin Med Perin 112:203-246
15. Gosling RG, King DH 1974 Continuous wave ultrasound as an alternative and complement to x-rays in vascular examinations. In: Reneman RS (eds) Cardiovascular Applications of Ultrasound. North Holland, Amsterdam, pp 266-282
16. + uptake by human placental microvillous membrane vesicles prepared by three different methods. Biochim Biophys Acta 945:127-134
17. Kuruvilla AJ, D'Souza SW, Glazier JD, Mahendran D, Maresh M, Sibley CP 1994 Altered activity of the System A amino acid transporter in microvillous membrane vesicles from placentas of macrosomic babies born to diabetic women. J Clin Invest 94:689-695
18. +-dependent amino acid uptake by human placental microvillous membrane vesicles: importance of storage conditions and preservation of cytoskeletal elements. Placenta 12:239-250
19. Kudo Y, Yamada K, Fujiwara A, Kawasaki T 1987 Characterisation of amino acid transport systems in human placental brush-border membrane vesicles. Biochim Biophys Acta 904:309-318
20. Cetin I, Ronzoni S, Marconi AM, Perugino G, Corbetta C, Battaglia FC, Pardi G 1996 Maternal concentrations and fetal-maternal concentration differences of plasma amino acids in normal (AGA) and intrauterine growth restricted pregnancies. Am J Obstet Gynecol 174:1575-1583
21. Cetin I, Marconi AM, Baggiani AM, Bus̄caglia M, Pardi G, Fennessey PV, Battaglia FC 1995 In vivo placental transport of glycine and leucine in human pregnancies. Pediatr Res 37:571-575
22. Dicke JM, Verges DK 1994 Neutral amino acid uptake by microvillous and basal plasma membrane vesicles from appropriate and small for gestational age human pregnancies. J Matern Fetal Med 3:246-250
23. Ross JC, Fennessey PV, Wilkening RB, Battaglia FC, Meschia G 1996 Placental transport and fetal utilization of leucine in a model of fetal growth retardation. Am J Physiol 270:E491-E503