메뉴 건너뛰기




Volumn 422, Issue , 2016, Pages 221-232

A novel rat model of gestational diabetes induced by intrauterine programming is associated with alterations in placental signaling and fetal overgrowth

Author keywords

Gestational diabetes mellitus; Intrauterine programming; mTOR; Placenta; PPAR

Indexed keywords

GLUCOSE; INITIATION FACTOR 4E BINDING PROTEIN 1; NITRIC OXIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE C ALPHA; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; MTOR PROTEIN, RAT; PLACENTA PROTEIN; TARGET OF RAPAMYCIN KINASE;

EID: 84956594691     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2015.12.020     Document Type: Article
Times cited : (46)

References (49)
  • 1
    • 84945449592 scopus 로고    scopus 로고
    • Gestational diabetes mellitus: where are we now?
    • Ashwal E., Hod M. Gestational diabetes mellitus: where are we now?. Clin. Chim. Acta 2015, 451:14-20.
    • (2015) Clin. Chim. Acta , vol.451 , pp. 14-20
    • Ashwal, E.1    Hod, M.2
  • 2
    • 84956595879 scopus 로고    scopus 로고
    • TNF-alpha stimulates system A amino acid transport in primary human trophoblast cells mediated by p38 MAPK signaling
    • Aye I.L., Jansson T., Powell T.L. TNF-alpha stimulates system A amino acid transport in primary human trophoblast cells mediated by p38 MAPK signaling. Physiol. Rep. 2015, 3(10):e12594.
    • (2015) Physiol. Rep. , vol.3 , Issue.10
    • Aye, I.L.1    Jansson, T.2    Powell, T.L.3
  • 3
    • 65649084159 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis
    • Bellamy L., Casas J.P., Hingorani A.D., Williams D. Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. Lancet 2009, 373:1773-1779.
    • (2009) Lancet , vol.373 , pp. 1773-1779
    • Bellamy, L.1    Casas, J.P.2    Hingorani, A.D.3    Williams, D.4
  • 5
    • 84890149646 scopus 로고    scopus 로고
    • Where is mTOR and what is it doing there?
    • Betz C., Hall M.N. Where is mTOR and what is it doing there?. J. Cell Biol. 2013, 203:563-574.
    • (2013) J. Cell Biol. , vol.203 , pp. 563-574
    • Betz, C.1    Hall, M.N.2
  • 7
    • 14644409707 scopus 로고    scopus 로고
    • Gestational diabetes mellitus
    • Buchanan T.A., Xiang A.H. Gestational diabetes mellitus. J. Clin. Invest 2005, 115:485-491.
    • (2005) J. Clin. Invest , vol.115 , pp. 485-491
    • Buchanan, T.A.1    Xiang, A.H.2
  • 8
    • 84880338336 scopus 로고    scopus 로고
    • PPAR activation as a regulator of lipid metabolism, nitric oxide production and lipid peroxidation in the placenta from type 2 diabetic patients
    • Capobianco E., Martinez N., Fornes D., Higa R., Di Marco I., Basualdo M.N., Faingold M.C., Jawerbaum A. PPAR activation as a regulator of lipid metabolism, nitric oxide production and lipid peroxidation in the placenta from type 2 diabetic patients. Mol. Cell Endocrinol. 2013, 377:7-15.
    • (2013) Mol. Cell Endocrinol. , vol.377 , pp. 7-15
    • Capobianco, E.1    Martinez, N.2    Fornes, D.3    Higa, R.4    Di Marco, I.5    Basualdo, M.N.6    Faingold, M.C.7    Jawerbaum, A.8
  • 9
    • 84942826245 scopus 로고    scopus 로고
    • Intrauterine programming of lipid metabolic alterations in the heart of the offspring of diabetic rats is prevented by maternal diets enriched in olive oil
    • Capobianco E., Pelesson M., Careaga V., Fornes D., Canosa I., Higa R., Maier M., Jawerbaum A. Intrauterine programming of lipid metabolic alterations in the heart of the offspring of diabetic rats is prevented by maternal diets enriched in olive oil. Mol. Nutr. Food Res. 2015, 59:1997-2007.
    • (2015) Mol. Nutr. Food Res. , vol.59 , pp. 1997-2007
    • Capobianco, E.1    Pelesson, M.2    Careaga, V.3    Fornes, D.4    Canosa, I.5    Higa, R.6    Maier, M.7    Jawerbaum, A.8
  • 10
    • 84928326971 scopus 로고    scopus 로고
    • The role of placental nutrient sensing in maternal-fetal resource allocation
    • Diaz P., Powell T.L., Jansson T. The role of placental nutrient sensing in maternal-fetal resource allocation. Biol. Reprod. 2014, 91:82.
    • (2014) Biol. Reprod. , vol.91 , pp. 82
    • Diaz, P.1    Powell, T.L.2    Jansson, T.3
  • 11
    • 84899786094 scopus 로고    scopus 로고
    • Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2alpha signaling and increases fetal growth in rats
    • Gaccioli F., White V., Capobianco E., Powell T.L., Jawerbaum A., Jansson T. Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2alpha signaling and increases fetal growth in rats. Biol. Reprod. 2013, 89:96.
    • (2013) Biol. Reprod. , vol.89 , pp. 96
    • Gaccioli, F.1    White, V.2    Capobianco, E.3    Powell, T.L.4    Jawerbaum, A.5    Jansson, T.6
  • 13
    • 84904751569 scopus 로고    scopus 로고
    • Lipid metabolism during pregnancy and its implications for fetal growth
    • Herrera E., Ortega-Senovilla H. Lipid metabolism during pregnancy and its implications for fetal growth. Curr. Pharm. Biotechnol. 2014, 15:24-31.
    • (2014) Curr. Pharm. Biotechnol. , vol.15 , pp. 24-31
    • Herrera, E.1    Ortega-Senovilla, H.2
  • 14
    • 67449155317 scopus 로고    scopus 로고
    • Insulin and the IGF system in the human placenta of normal and diabetic pregnancies
    • Hiden U., Glitzner E., Hartmann M., Desoye G. Insulin and the IGF system in the human placenta of normal and diabetic pregnancies. J. Anat. 2009, 215:60-68.
    • (2009) J. Anat. , vol.215 , pp. 60-68
    • Hiden, U.1    Glitzner, E.2    Hartmann, M.3    Desoye, G.4
  • 15
    • 84877958989 scopus 로고    scopus 로고
    • Intrauterine effects of impaired lipid homeostasis in pregnancy diseases
    • Higa R., Jawerbaum A. Intrauterine effects of impaired lipid homeostasis in pregnancy diseases. Curr. Med. Chem. 2013, 20:2338-2350.
    • (2013) Curr. Med. Chem. , vol.20 , pp. 2338-2350
    • Higa, R.1    Jawerbaum, A.2
  • 16
    • 77049111523 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors are altered in pathologies of the human placenta: gestational diabetes mellitus, intrauterine growth restriction and preeclampsia
    • Holdsworth-Carson S.J., Lim R., Mitton A., Whitehead C., Rice G.E., Permezel M., Lappas M. Peroxisome proliferator-activated receptors are altered in pathologies of the human placenta: gestational diabetes mellitus, intrauterine growth restriction and preeclampsia. Placenta 2010, 31:222-229.
    • (2010) Placenta , vol.31 , pp. 222-229
    • Holdsworth-Carson, S.J.1    Lim, R.2    Mitton, A.3    Whitehead, C.4    Rice, G.E.5    Permezel, M.6    Lappas, M.7
  • 19
    • 84869094274 scopus 로고    scopus 로고
    • The emerging role of mTORC1 signaling in placental nutrient-sensing
    • Jansson T., Aye I.L., Goberdhan D.C. The emerging role of mTORC1 signaling in placental nutrient-sensing. Placenta 2012, 33(Suppl. 2):e23-e29.
    • (2012) Placenta , vol.33 , pp. e23-e29
    • Jansson, T.1    Aye, I.L.2    Goberdhan, D.C.3
  • 20
    • 0036307306 scopus 로고    scopus 로고
    • Alterations in the activity of placental amino acid transporters in pregnancies complicated by diabetes
    • Jansson T., Ekstrand Y., Bjorn C., Wennergren M., Powell T.L. Alterations in the activity of placental amino acid transporters in pregnancies complicated by diabetes. Diabetes 2002, 51:2214-2219.
    • (2002) Diabetes , vol.51 , pp. 2214-2219
    • Jansson, T.1    Ekstrand, Y.2    Bjorn, C.3    Wennergren, M.4    Powell, T.L.5
  • 21
    • 79952002653 scopus 로고    scopus 로고
    • Review: effects of PPAR activation in the placenta and the fetus: implications in maternal diabetes
    • Jawerbaum A., Capobianco E. Review: effects of PPAR activation in the placenta and the fetus: implications in maternal diabetes. Placenta 2011, 32(Suppl. 2):S212-S217.
    • (2011) Placenta , vol.32 , pp. S212-S217
    • Jawerbaum, A.1    Capobianco, E.2
  • 22
    • 5044245034 scopus 로고    scopus 로고
    • Influence of peroxisome proliferator-activated receptor gamma activation by its endogenous ligand 15-deoxy Delta12,14 prostaglandin J2 on nitric oxide production in term placental tissues from diabetic women
    • Jawerbaum A., Capobianco E., Pustovrh C., White V., Baier M., Salzberg S., Pesaresi M., Gonzalez E. Influence of peroxisome proliferator-activated receptor gamma activation by its endogenous ligand 15-deoxy Delta12,14 prostaglandin J2 on nitric oxide production in term placental tissues from diabetic women. Mol. Hum. Reprod. 2004, 10:671-676.
    • (2004) Mol. Hum. Reprod. , vol.10 , pp. 671-676
    • Jawerbaum, A.1    Capobianco, E.2    Pustovrh, C.3    White, V.4    Baier, M.5    Salzberg, S.6    Pesaresi, M.7    Gonzalez, E.8
  • 23
    • 33746538871 scopus 로고    scopus 로고
    • Diabetic pregnancies: the challenge of developing in a pro-inflammatory environment
    • Jawerbaum A., Gonzalez E. Diabetic pregnancies: the challenge of developing in a pro-inflammatory environment. Curr. Med. Chem. 2006, 13:2127-2138.
    • (2006) Curr. Med. Chem. , vol.13 , pp. 2127-2138
    • Jawerbaum, A.1    Gonzalez, E.2
  • 24
    • 77958166094 scopus 로고    scopus 로고
    • Animal models in diabetes and pregnancy
    • Jawerbaum A., White V. Animal models in diabetes and pregnancy. Endocr. Rev. 2010, 31:680-701.
    • (2010) Endocr. Rev. , vol.31 , pp. 680-701
    • Jawerbaum, A.1    White, V.2
  • 25
    • 84930606826 scopus 로고    scopus 로고
    • Gestational diabetes mellitus and macrosomia: a literature review
    • Kc K., Shakya S., Zhang H. Gestational diabetes mellitus and macrosomia: a literature review. Ann. Nutr. Metabol. 2015, 66(Suppl. 2):14-20.
    • (2015) Ann. Nutr. Metabol. , vol.66 , pp. 14-20
    • Kc, K.1    Shakya, S.2    Zhang, H.3
  • 26
    • 0036781530 scopus 로고    scopus 로고
    • Gestational diabetes and the incidence of type 2 diabetes: a systematic review
    • Kim C., Newton K.M., Knopp R.H. Gestational diabetes and the incidence of type 2 diabetes: a systematic review. Diabetes Care 2002, 25:1862-1868.
    • (2002) Diabetes Care , vol.25 , pp. 1862-1868
    • Kim, C.1    Newton, K.M.2    Knopp, R.H.3
  • 28
    • 84877965001 scopus 로고    scopus 로고
    • Regulation of mTORC1 and its impact on gene expression at a glance
    • Laplante M., Sabatini D.M. Regulation of mTORC1 and its impact on gene expression at a glance. J. Cell Sci. 2013, 126:1713-1719.
    • (2013) J. Cell Sci. , vol.126 , pp. 1713-1719
    • Laplante, M.1    Sabatini, D.M.2
  • 30
    • 4544294573 scopus 로고    scopus 로고
    • Triglyceride hydrolase activities and expression of fatty acid binding proteins in the human placenta in pregnancies complicated by intrauterine growth restriction and diabetes
    • Magnusson A.L., Waterman I.J., Wennergren M., Jansson T., Powell T.L. Triglyceride hydrolase activities and expression of fatty acid binding proteins in the human placenta in pregnancies complicated by intrauterine growth restriction and diabetes. J. Clin. Endocrinol. Metab. 2004, 89:4607-4614.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 4607-4614
    • Magnusson, A.L.1    Waterman, I.J.2    Wennergren, M.3    Jansson, T.4    Powell, T.L.5
  • 31
    • 79960999898 scopus 로고    scopus 로고
    • PPARalpha agonists regulate lipid metabolism and nitric oxide production and prevent placental overgrowth in term placentas from diabetic rats
    • Martinez N., Kurtz M., Capobianco E., Higa R., White V., Jawerbaum A. PPARalpha agonists regulate lipid metabolism and nitric oxide production and prevent placental overgrowth in term placentas from diabetic rats. J. Mol. Endocrinol. 2011, 47:1-12.
    • (2011) J. Mol. Endocrinol. , vol.47 , pp. 1-12
    • Martinez, N.1    Kurtz, M.2    Capobianco, E.3    Higa, R.4    White, V.5    Jawerbaum, A.6
  • 32
    • 84655163870 scopus 로고    scopus 로고
    • Dietary treatments enriched in olive and safflower oils regulate seric and placental matrix metalloproteinases in maternal diabetes
    • Martinez N., Sosa M., Higa R., Fornes D., Capobianco E., Jawerbaum A. Dietary treatments enriched in olive and safflower oils regulate seric and placental matrix metalloproteinases in maternal diabetes. Placenta 2012, 33:8-16.
    • (2012) Placenta , vol.33 , pp. 8-16
    • Martinez, N.1    Sosa, M.2    Higa, R.3    Fornes, D.4    Capobianco, E.5    Jawerbaum, A.6
  • 34
    • 84921669318 scopus 로고    scopus 로고
    • Effect of preeclampsia on placental function: influence of sexual dimorphism, microRNA's and mitochondria
    • Myatt L., Muralimanoharan S., Maloyan A. Effect of preeclampsia on placental function: influence of sexual dimorphism, microRNA's and mitochondria. Adv. Exp. Med. Biol. 2014, 814:133-146.
    • (2014) Adv. Exp. Med. Biol. , vol.814 , pp. 133-146
    • Myatt, L.1    Muralimanoharan, S.2    Maloyan, A.3
  • 36
    • 79960470913 scopus 로고    scopus 로고
    • MTOR complex 2 signaling and functions
    • Oh W.J., Jacinto E. mTOR complex 2 signaling and functions. Cell Cycle 2011, 10:2305-2316.
    • (2011) Cell Cycle , vol.10 , pp. 2305-2316
    • Oh, W.J.1    Jacinto, E.2
  • 37
    • 84930754244 scopus 로고    scopus 로고
    • Inflammation in maternal obesity and gestational diabetes mellitus
    • Pantham P., Aye I.L., Powell T.L. Inflammation in maternal obesity and gestational diabetes mellitus. Placenta 2015, 36:709-715.
    • (2015) Placenta , vol.36 , pp. 709-715
    • Pantham, P.1    Aye, I.L.2    Powell, T.L.3
  • 40
    • 59749101802 scopus 로고    scopus 로고
    • Placental mTOR links maternal nutrient availability to fetal growth
    • Roos S., Powell T.L., Jansson T. Placental mTOR links maternal nutrient availability to fetal growth. Biochem. Soc. Trans. 2009, 37:295-298.
    • (2009) Biochem. Soc. Trans. , vol.37 , pp. 295-298
    • Roos, S.1    Powell, T.L.2    Jansson, T.3
  • 41
    • 79951938584 scopus 로고    scopus 로고
    • Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters
    • Rosario F.J., Jansson N., Kanai Y., Prasad P.D., Powell T.L., Jansson T. Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters. Endocrinology 2011, 152:1119-1129.
    • (2011) Endocrinology , vol.152 , pp. 1119-1129
    • Rosario, F.J.1    Jansson, N.2    Kanai, Y.3    Prasad, P.D.4    Powell, T.L.5    Jansson, T.6
  • 42
    • 84873156962 scopus 로고    scopus 로고
    • Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells
    • Rosario F.J., Kanai Y., Powell T.L., Jansson T. Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells. J. Physiol. 2013, 591:609-625.
    • (2013) J. Physiol. , vol.591 , pp. 609-625
    • Rosario, F.J.1    Kanai, Y.2    Powell, T.L.3    Jansson, T.4
  • 43
    • 84925500524 scopus 로고    scopus 로고
    • Pre-gestational vs gestational exposure to maternal obesity differentially programs the offspring in mice
    • Sasson I.E., Vitins A.P., Mainigi M.A., Moley K.H., Simmons R.A. Pre-gestational vs gestational exposure to maternal obesity differentially programs the offspring in mice. Diabetologia 2015, 58:615-624.
    • (2015) Diabetologia , vol.58 , pp. 615-624
    • Sasson, I.E.1    Vitins, A.P.2    Mainigi, M.A.3    Moley, K.H.4    Simmons, R.A.5
  • 44
    • 84946431008 scopus 로고    scopus 로고
    • MTOR pathway inhibition prevents neuroinflammation and neuronal death in a mouse model of cerebral palsy
    • Srivastava I.N., Shperdheja J., Baybis M., Ferguson T., Crino P.B. mTOR pathway inhibition prevents neuroinflammation and neuronal death in a mouse model of cerebral palsy. Neurobiol. Dis. 2015, 85:144-154.
    • (2015) Neurobiol. Dis. , vol.85 , pp. 144-154
    • Srivastava, I.N.1    Shperdheja, J.2    Baybis, M.3    Ferguson, T.4    Crino, P.B.5
  • 45
    • 84863104065 scopus 로고    scopus 로고
    • PPARs at the crossroads of lipid signaling and inflammation
    • Wahli W., Michalik L. PPARs at the crossroads of lipid signaling and inflammation. Trends Endocrinol. Metab. 2012, 23:351-363.
    • (2012) Trends Endocrinol. Metab. , vol.23 , pp. 351-363
    • Wahli, W.1    Michalik, L.2
  • 46
    • 84875209235 scopus 로고    scopus 로고
    • Incidence of adverse outcomes associated with gestational diabetes mellitus in low- and middle-income countries
    • Wang Z., Kanguru L., Hussein J., Fitzmaurice A., Ritchie K. Incidence of adverse outcomes associated with gestational diabetes mellitus in low- and middle-income countries. Int. J. Gynaecol. Obstet. 2013, 121:14-19.
    • (2013) Int. J. Gynaecol. Obstet. , vol.121 , pp. 14-19
    • Wang, Z.1    Kanguru, L.2    Hussein, J.3    Fitzmaurice, A.4    Ritchie, K.5
  • 47
    • 84927948958 scopus 로고    scopus 로고
    • Diabetes-associated changes in the fetal insulin/insulin-like growth factor system are organ specific in rats
    • White V., Jawerbaum A., Mazzucco M.B., Gauster M., Desoye G., Hiden U. Diabetes-associated changes in the fetal insulin/insulin-like growth factor system are organ specific in rats. Pediatr. Res. 2015, 77:48-55.
    • (2015) Pediatr. Res. , vol.77 , pp. 48-55
    • White, V.1    Jawerbaum, A.2    Mazzucco, M.B.3    Gauster, M.4    Desoye, G.5    Hiden, U.6
  • 48
    • 84994405563 scopus 로고    scopus 로고
    • Mammalian target of rapamycin mediates kidney injury molecule 1-Dependent tubule injury in a surrogate model
    • November 4, JASN November 4, 2015 ASN.2015050500
    • Yin W., Naini S.M., Chen G., Hentschel D.M., Humphreys B.D., Bonventre J.V. Mammalian target of rapamycin mediates kidney injury molecule 1-Dependent tubule injury in a surrogate model. J. Am. Soc. Nephrol. November 4, 2015, JASN November 4, 2015 ASN.2015050500. 10.1681/ASN.2015050500.
    • (2015) J. Am. Soc. Nephrol.
    • Yin, W.1    Naini, S.M.2    Chen, G.3    Hentschel, D.M.4    Humphreys, B.D.5    Bonventre, J.V.6
  • 49
    • 84886257557 scopus 로고    scopus 로고
    • Mechanisms by which maternal obesity programs offspring for obesity: evidence from animal studies
    • Zambrano E., Nathanielsz P.W. Mechanisms by which maternal obesity programs offspring for obesity: evidence from animal studies. Nutr. Rev. 2013, 71(Suppl. 1):S42-S54.
    • (2013) Nutr. Rev. , vol.71 , pp. S42-S54
    • Zambrano, E.1    Nathanielsz, P.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.