MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells

Biochemical and Biophysical Research Communications

Volumn 396, Issue 4, 2010, Pages 956-960

  Pérez Pérez, Antonio ^a   Gambino, Yésica ^b   Maymó, Julieta ^b   Goberna, Raimundo ^a   Fabiani, Fernando ^a   Varone, Cecilia ^b   Sánchez Margalet, Víctor ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN MACARENA   (Spain)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Leptin; Placenta; Protein synthesis; Signal transduction; Translation

Indexed keywords

DNA; INITIATION FACTOR 4E; INITIATION FACTOR 4E BINDING PROTEIN 1; JANUS KINASE; LEPTIN; LEPTIN RECEPTOR; LEUCINE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; S6 KINASE; STAT PROTEIN; TRITIUM;

APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CELL GROWTH; CHORIOCARCINOMA; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PREGNANCY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; PROTEIN SYNTHESIS REGULATION; SIGNAL TRANSDUCTION; TRANSLATION INITIATION; TROPHOBLAST;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL LINE, TUMOR; EUKARYOTIC INITIATION FACTOR-4E; FEMALE; HUMANS; LEPTIN; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHOPROTEINS; PHOSPHORYLATION; PREGNANCY; PROTEIN BIOSYNTHESIS; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; TROPHOBLASTS;

EID: 77953289537     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.05.031     Document Type: Article

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