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Volumn 24, Issue 24, 2004, Pages 10766-10776

5-Fluorouracil enhances exosome-dependent accumulation of polyadenylated rRNAs

Author keywords

[No Author keywords available]

Indexed keywords

EXORIBONUCLEASE; FLUOROURACIL; POLYADENYLATED RNA; PROTEIN RRP6P; RIBOSOME RNA; RNA PRECURSOR; THYMIDINE PHOSPHATE; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG;

EID: 10044286102     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.24.10766-10776.2004     Document Type: Article
Times cited : (74)

References (47)
  • 3
    • 0033567131 scopus 로고    scopus 로고
    • The yeast exosome and human PM-Scl are related complexes of 3′ → 5′ exonucleases
    • Allmang, C., E. Petfalski, A. Podtelejnikov, M. Mann, D. Tollervey, and P. Mitchell. 1999. The yeast exosome and human PM-Scl are related complexes of 3′ → 5′ exonucleases. Genes Dev. 13:2148-2158.
    • (1999) Genes Dev. , vol.13 , pp. 2148-2158
    • Allmang, C.1    Petfalski, E.2    Podtelejnikov, A.3    Mann, M.4    Tollervey, D.5    Mitchell, P.6
  • 4
    • 0032557455 scopus 로고    scopus 로고
    • Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3′ end formation
    • Briggs, M. W., K. T. Burkard, and J. S. Butler. 1998. Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3′ end formation. J. Biol. Chem. 273:13255-13263.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13255-13263
    • Briggs, M.W.1    Burkard, K.T.2    Butler, J.S.3
  • 7
    • 0025782828 scopus 로고
    • Protein synthesis requirements for nuclear division, cytokinesis, and cell separation in Saccharomyces cerevisiae
    • Burke, D. J., and D. Church. 1991. Protein synthesis requirements for nuclear division, cytokinesis, and cell separation in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:3691-3698.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 3691-3698
    • Burke, D.J.1    Church, D.2
  • 8
    • 0036469214 scopus 로고    scopus 로고
    • The yin and yang of the exosome
    • Butler, J. S. 2002. The yin and yang of the exosome. Trends Cell Biol. 12:90-96.
    • (2002) Trends Cell Biol. , vol.12 , pp. 90-96
    • Butler, J.S.1
  • 9
    • 0032916509 scopus 로고    scopus 로고
    • mRNA degradation. A tale of poly(A) and multiprotein machines
    • Carpousis, A. J., N. F. Vanzo, and L. C. Raynal. 1999. mRNA degradation. A tale of poly(A) and multiprotein machines. Trends Genet. 15:24-28.
    • (1999) Trends Genet. , vol.15 , pp. 24-28
    • Carpousis, A.J.1    Vanzo, N.F.2    Raynal, L.C.3
  • 10
    • 0018578292 scopus 로고
    • Effect of 5-fluorouracil on RNA metabolism in Novikoff hepatoma cells
    • Cory, J. G., J. C. Breland, and G. L. Carter. 1979. Effect of 5-fluorouracil on RNA metabolism in Novikoff hepatoma cells. Cancer Res. 39:4905-4913.
    • (1979) Cancer Res. , vol.39 , pp. 4905-4913
    • Cory, J.G.1    Breland, J.C.2    Carter, G.L.3
  • 11
    • 0037188922 scopus 로고    scopus 로고
    • Yph1p, an ORC-interacting protein: Potential links between cell proliferation control, DNA replication, and ribosome biogenesis
    • Du, Y. C., and B. Stillman. 2002. Yph1p, an ORC-interacting protein: potential links between cell proliferation control, DNA replication, and ribosome biogenesis. Cell 109:835-848.
    • (2002) Cell , vol.109 , pp. 835-848
    • Du, Y.C.1    Stillman, B.2
  • 12
    • 0032582521 scopus 로고    scopus 로고
    • Mak21p of Saccharomyces cerevisiae, a homolog of human CAATT-binding protein, is essential for 60 S ribosomal subunit biogenesis
    • Edskes, H. K., Y. Ohtake, and R. B. Wickner. 1998. Mak21p of Saccharomyces cerevisiae, a homolog of human CAATT-binding protein, is essential for 60 S ribosomal subunit biogenesis. J. Biol. Chem. 273:28912-28920.
    • (1998) J. Biol. Chem. , vol.273 , pp. 28912-28920
    • Edskes, H.K.1    Ohtake, Y.2    Wickner, R.B.3
  • 13
    • 0021353296 scopus 로고
    • Modulation of 5-fluorouracil metabolism by thymidine. In vivo and in vitro studies on RNA-directed effects in rat liver and hepatoma
    • Engelbrecht, C., I. Ljungquist, L. Lewan, and T. Yngner. 1984. Modulation of 5-fluorouracil metabolism by thymidine. In vivo and in vitro studies on RNA-directed effects in rat liver and hepatoma. Biochem. Pharmacol. 33:745-750.
    • (1984) Biochem. Pharmacol. , vol.33 , pp. 745-750
    • Engelbrecht, C.1    Ljungquist, I.2    Lewan, L.3    Yngner, T.4
  • 14
    • 0030739913 scopus 로고    scopus 로고
    • An alternative molecular mechanism of action of 5-fluorouracil, a potent anticancer drug
    • Ghoshal, K., and S. T. Jacob. 1997. An alternative molecular mechanism of action of 5-fluorouracil, a potent anticancer drug. Biochem. Pharmacol. 53:1569-1575.
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 1569-1575
    • Ghoshal, K.1    Jacob, S.T.2
  • 16
    • 0025214307 scopus 로고
    • Effect of 5-fluorouracil combination therapy on RNA processing in human colonic carcinoma cells
    • Greenhalgh, D. A., and J. H. Parish. 1990. Effect of 5-fluorouracil combination therapy on RNA processing in human colonic carcinoma cells. Br. J. Cancer 61:415-419.
    • (1990) Br. J. Cancer , vol.61 , pp. 415-419
    • Greenhalgh, D.A.1    Parish, J.H.2
  • 17
    • 0024330933 scopus 로고
    • Effects of 5-fluorouracil on cytotoxicity and RNA metabolism in human colonic carcinoma cells
    • Greenhalgh, D. A., and J. H. Parish. 1989. Effects of 5-fluorouracil on cytotoxicity and RNA metabolism in human colonic carcinoma cells. Cancer Chemother. Pharmacol. 25:37-44.
    • (1989) Cancer Chemother. Pharmacol. , vol.25 , pp. 37-44
    • Greenhalgh, D.A.1    Parish, J.H.2
  • 18
    • 0027466092 scopus 로고
    • Alternative pre-rRNA processing pathways in human cells and their alteration by cycloheximide inhibition of protein synthesis
    • Hadjiolova, K. V., M. Nicoloso, S. Mazan, A. A. Hadjiolov, and J. P. Bachellerie. 1993. Alternative pre-rRNA processing pathways in human cells and their alteration by cycloheximide inhibition of protein synthesis. Eur. J. Biochem. 212:211-215.
    • (1993) Eur. J. Biochem. , vol.212 , pp. 211-215
    • Hadjiolova, K.V.1    Nicoloso, M.2    Mazan, S.3    Hadjiolov, A.A.4    Bachellerie, J.P.5
  • 19
    • 0345276485 scopus 로고    scopus 로고
    • Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation
    • Itahana, K., K. P. Bhat, A. Jin, Y. Itahana, D. Hawke, R. Kobayashi, and Y. Zhang. 2003. Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation. Mol. Cell 12:1151-1164.
    • (2003) Mol. Cell , vol.12 , pp. 1151-1164
    • Itahana, K.1    Bhat, K.P.2    Jin, A.3    Itahana, Y.4    Hawke, D.5    Kobayashi, R.6    Zhang, Y.7
  • 20
    • 0030764692 scopus 로고    scopus 로고
    • Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively
    • Johnson, A. W. 1997. Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively. Mol. Cell. Biol. 17:6122-6130.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6122-6130
    • Johnson, A.W.1
  • 21
    • 2642574393 scopus 로고    scopus 로고
    • Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae
    • Kadaba, S., A. Krueger, T. Trice, A. M. Krecic, A. G. Hinnebusch, and J. Anderson. 2004. Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae. Genes Dev. 18:1227-1240.
    • (2004) Genes Dev. , vol.18 , pp. 1227-1240
    • Kadaba, S.1    Krueger, A.2    Trice, T.3    Krecic, A.M.4    Hinnebusch, A.G.5    Anderson, J.6
  • 25
    • 0027987215 scopus 로고
    • Incorporation of 5-fluorouracil into U2 and U6 snRNA inhibits mRNA precursor splicing
    • Lenz, H. J., D. J. Manno, K. D. Danenberg, and P. V. Danenberg. 1994. Incorporation of 5-fluorouracil into U2 and U6 snRNA inhibits mRNA precursor splicing. J. Biol. Chem. 269:31962-31968.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31962-31968
    • Lenz, H.J.1    Manno, D.J.2    Danenberg, K.D.3    Danenberg, P.V.4
  • 26
    • 0029964158 scopus 로고    scopus 로고
    • A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage
    • Linke, S. P., K. C. Clarkin, A. Di Leonardo, A. Tsou, and G. M. Wahl. 1996. A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes Dev. 10:934-947.
    • (1996) Genes Dev. , vol.10 , pp. 934-947
    • Linke, S.P.1    Clarkin, K.C.2    Di Leonardo, A.3    Tsou, A.4    Wahl, G.M.5
  • 27
    • 0038387494 scopus 로고    scopus 로고
    • 5-Fluorouracil: Mechanisms of action and clinical strategies
    • Longley, D. B., D. P. Harkin, and P. G. Johnston. 2003. 5-Fluorouracil: mechanisms of action and clinical strategies. Nat. Rev. Cancer 3:330-338.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 330-338
    • Longley, D.B.1    Harkin, D.P.2    Johnston, P.G.3
  • 30
    • 0030702085 scopus 로고    scopus 로고
    • The exosome: A conserved eukaryotic RNA processing complex containing multiple 3′→5′ exoribonucleases
    • Mitchell, P., E. Petfalski, A. Shevchenko, M. Mann, and D. Tollervey. 1997. The exosome: a conserved eukaryotic RNA processing complex containing multiple 3′→5′ exoribonucleases. Cell 91:457-466.
    • (1997) Cell , vol.91 , pp. 457-466
    • Mitchell, P.1    Petfalski, E.2    Shevchenko, A.3    Mann, M.4    Tollervey, D.5
  • 31
    • 0033457296 scopus 로고    scopus 로고
    • Analysis of the function of Escherichia coli poly(A) polymerase I in RNA metabolism
    • Mohanty, B. K., and S. R. Kushner. 1999. Analysis of the function of Escherichia coli poly(A) polymerase I in RNA metabolism. Mol Met. Microbiol. 34:1094-1108.
    • (1999) Mol Met. Microbiol. , vol.34 , pp. 1094-1108
    • Mohanty, B.K.1    Kushner, S.R.2
  • 32
    • 12144288857 scopus 로고    scopus 로고
    • Sensing cellular stress: Another new function for the nucleolus?
    • 16 March 2004, posting date. [Online]
    • Olson, M. O. 16 March 2004, posting date. Sensing cellular stress: another new function for the nucleolus? Sci. STKE 2004: pe10. [Online.] http://stke.sciencemag.org.
    • (2004) Sci. STKE
    • Olson, M.O.1
  • 33
    • 0025611018 scopus 로고
    • Metabolism and mechanism of action of 5-fluorouracil
    • Parker, W. B., and Y. C. Cheng. 1990. Metabolism and mechanism of action of 5-fluorouracil. Pharmacol. Ther. 48:381-395.
    • (1990) Pharmacol. Ther. , vol.48 , pp. 381-395
    • Parker, W.B.1    Cheng, Y.C.2
  • 34
    • 0026770680 scopus 로고
    • Conditional defect in mRNA 3′ end processing caused by a mutation in the gene for poly(A) polymerase
    • Patel, D., and J. S. Butler. 1992. Conditional defect in mRNA 3′ end processing caused by a mutation in the gene for poly(A) polymerase. Mol. Cell. Biol. 12:3297-3304.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3297-3304
    • Patel, D.1    Butler, J.S.2
  • 37
    • 0042834089 scopus 로고    scopus 로고
    • Contribution of domain structure to the RNA processing and degradation functions of the nuclear exosome subunit Rrp6p
    • Phillips, S., and J. S. Butler. 2003. Contribution of domain structure to the RNA processing and degradation functions of the nuclear exosome subunit Rrp6p. RNA 9:1098-1107.
    • (2003) RNA , vol.9 , pp. 1098-1107
    • Phillips, S.1    Butler, J.S.2
  • 38
    • 12644291915 scopus 로고    scopus 로고
    • Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: Evidence for the involvement of RNA perturbation
    • Pritchard, D. M., A. J. Watson, C. S. Potten, A. L. Jackman, and J. A. Hickman. 1997. Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbation. Proc. Natl. Acad. Sci. USA 94:1795-1799.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 1795-1799
    • Pritchard, D.M.1    Watson, A.J.2    Potten, C.S.3    Jackman, A.L.4    Hickman, J.A.5
  • 39
    • 0031041083 scopus 로고    scopus 로고
    • Ribosome concentration contributes to discrimination against poly(A)-mRNA during translation initiation in Saccharomyces cerevisiae
    • Proweller, A., and J. S. Butler. 1997. Ribosome concentration contributes to discrimination against poly(A)-mRNA during translation initiation in Saccharomyces cerevisiae. J. Biol. Chem. 272:6004-6010.
    • (1997) J. Biol. Chem. , vol.272 , pp. 6004-6010
    • Proweller, A.1    Butler, J.S.2
  • 40
    • 0037363075 scopus 로고    scopus 로고
    • Does the ribosome translate cancer?
    • Ruggero, D., and P. P. Pandolfi. 2003. Does the ribosome translate cancer? Nat. Rev. Cancer 3:179-192.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 179-192
    • Ruggero, D.1    Pandolfi, P.P.2
  • 41
    • 0033912841 scopus 로고    scopus 로고
    • Bop1 is a mouse WD40 repeat nucleolar protein involved in 28S and 5.8S rRNA processing and 60S ribosome biogenesis
    • Strezoska, Z., D. G. Pestov, and L. F. Lau. 2000. Bop1 is a mouse WD40 repeat nucleolar protein involved in 28S and 5.8S rRNA processing and 60S ribosome biogenesis. Mol. Cell. Biol. 20:5516-5528.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 5516-5528
    • Strezoska, Z.1    Pestov, D.G.2    Lau, L.F.3
  • 42
    • 0037291204 scopus 로고    scopus 로고
    • Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing
    • Sugimoto, M., M. L. Kuo, M. F. Roussel, and C. J. Sherr. 2003. Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing. Mol. Cell 11:415-424.
    • (2003) Mol. Cell , vol.11 , pp. 415-424
    • Sugimoto, M.1    Kuo, M.L.2    Roussel, M.F.3    Sherr, C.J.4
  • 43
    • 0028357522 scopus 로고
    • The yeast NOP4 gene product is an essential nucleolar protein required for pre-rRNA processing and accumulation of 60S ribosomal subunits
    • Sun, C., and J. L. Woolford, Jr. 1994. The yeast NOP4 gene product is an essential nucleolar protein required for pre-rRNA processing and accumulation of 60S ribosomal subunits. EMBO J. 13:3127-3135.
    • (1994) EMBO J. , vol.13 , pp. 3127-3135
    • Sun, C.1    Woolford Jr., J.L.2
  • 44
    • 0033981301 scopus 로고    scopus 로고
    • Yeast exosome mutants accumulate 3′-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs
    • van Hoof, A., P. Lennertz, and R. Parker. 2000. Yeast exosome mutants accumulate 3′-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs. Mol. Cell. Biol. 20:441-452.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 441-452
    • Van Hoof, A.1    Lennertz, P.2    Parker, R.3
  • 46
    • 0032718276 scopus 로고    scopus 로고
    • Point mutations in yeast CBF5 can abolish in vivo pseudouridylation of rRNA
    • Zebarjadian, Y., T. King, M. J. Fournier, L. Clarke, and J. Carbon. 1999. Point mutations in yeast CBF5 can abolish in vivo pseudouridylation of rRNA. Mol. Cell. Biol. 19:7461-7472.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7461-7472
    • Zebarjadian, Y.1    King, T.2    Fournier, M.J.3    Clarke, L.4    Carbon, J.5
  • 47
    • 0037188889 scopus 로고    scopus 로고
    • Noc3p, a bHLH protein, plays an integral role in the initiation of DNA replication in budding yeast
    • Zhang, Y., Z. Yu, X. Fu, and C. Liang. 2002. Noc3p, a bHLH protein, plays an integral role in the initiation of DNA replication in budding yeast. Cell 109:849-860.
    • (2002) Cell , vol.109 , pp. 849-860
    • Zhang, Y.1    Yu, Z.2    Fu, X.3    Liang, C.4


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