Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds

Journal of Medicinal Chemistry

Volumn 45, Issue 14, 2002, Pages 3032-3040

  Heinisch, Lothar ^a   Wittmann, Steffen ^a,b   Stoiber, Thomas ^a,c   Berg, Albrecht ^a   Ankel Fuchs, Dorothe ^d   Möllmann, Ute ^a  

^a HANS KNÖLL INSTITUTE   (Germany)

^b BAYER PHARMA AG   (Germany)

^c FRITZ LIPMANN INSTITUTE   (Germany)

^d GRÜNENTHAL GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOACYLPENICILLIN DERIVATIVE; AMOXICILLIN DERIVATIVE; AMPICILLIN DERIVATIVE; ANTIBIOTIC AGENT; AZLOCILLIN; BENZOXAZINE DERIVATIVE; BETA LACTAM ANTIBIOTIC; CATECHOL DERIVATIVE; DEFEROXAMINE MESYLATE; HKI 9924154; HKI 9924155; MEROPENEM; PENICILLIN DERIVATIVE; PENICILLIN V; SIDEROPHORE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL OUTER MEMBRANE; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; KLEBSIELLA PNEUMONIAE; MEMBRANE PERMEABILITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PSEUDOMONAS AERUGINOSA; SERRATIA MARCESCENS; STENOTROPHOMONAS MALTOPHILIA;

AMINO ACIDS; AMOXICILLIN; AMPICILLIN; ANTI-BACTERIAL AGENTS; CATECHOLS; COLONY COUNT, MICROBIAL; GRAM-NEGATIVE BACTERIA; IRON CHELATING AGENTS; MICROBIAL SENSITIVITY TESTS; OXAZINES; PENICILLINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037019280     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010546b     Document Type: Article

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