Iron transport-mediated drug delivery: Practical syntheses and in vitro antibacterial studies of tris-catecholate siderophore-aminopenicillin conjugates reveals selectively potent antipseudomonal activity

Journal of the American Chemical Society

Volumn 134, Issue 24, 2012, Pages 9898-9901

  Ji, Cheng ^a   Miller, Patricia A ^a   Miller, Marvin J ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ANTI-BACTERIAL ACTIVITY; DRUG-CONJUGATES; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE SPECIES; IN-VITRO; IRON CONCENTRATIONS; IRON TRANSPORT; PSEUDOMONAS AERUGINOSA; SIDEROPHORES;

BACTERIA; DRUG DELIVERY;

IRON;

AMINOPENICILLIN; IRON; SIDEROPHORE;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; IN VITRO STUDY; IRON TRANSPORT; NONHUMAN; PSEUDOMONAS AERUGINOSA;

AMOXICILLIN; AMPICILLIN; ANTI-BACTERIAL AGENTS; BIOLOGICAL TRANSPORT; CATECHOLS; CHEMISTRY TECHNIQUES, SYNTHETIC; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; IRON; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SIDEROPHORES;

EID: 84862509089     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja303446w     Document Type: Article

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