Nuclear Factor E2-Related Factor-2 Negatively Regulates NLRP3 Inflammasome Activity by Inhibiting Reactive Oxygen Species-Induced NLRP3 Priming

Antioxidants and Redox Signaling

Volumn 26, Issue 1, 2017, Pages 28-43

  Liu, Xiuting ^a   Zhang, Xin ^a   Ding, Yang ^a   Zhou, Wei ^a   Tao, Lei ^a   Lu, Ping ^a   Wang, Yajing ^a   Hu, Rong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

NLRP3 inflammasome; Nrf2; Priming; ROS

Indexed keywords

ADENOSINE TRIPHOSPHATE; CATALASE; CRYOPYRIN; GLUTATHIONE; HYDROGEN PEROXIDE; INFLAMMASOME; INTERLEUKIN 1; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; ROTENONE; SMALL INTERFERING RNA; SUPEROXIDE; SUPEROXIDE DISMUTASE; TERT BUTYLHYDROQUINONE; TRANSCRIPTION FACTOR NRF2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; FEMALE; FLOW CYTOMETRY; GENETIC TRANSFECTION; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PERITONITIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL LINE; GENETICS; HUMAN; IMMUNOLOGY; MACROPHAGE; METABOLISM;

ADENOSINE TRIPHOSPHATE; ANIMALS; CATALASE; CELL LINE; FEMALE; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; INFLAMMASOMES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PERITONITIS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE;

EID: 85007586385     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2015.6615     Document Type: Article

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