NLRP3 activation induces ASC-dependent programmed necrotic cell death, which leads to neutrophilic inflammation

Cell Death and Disease

Volumn 4, Issue 5, 2013, Pages

  Satoh, T ^a   Kambe, N ^a   Matsue, H ^a  

^a CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

CAPS; IL 1 ; Inflammasome; Neutrophil; NLRP3; Programmed necrotic cell death

Indexed keywords

APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN CONTAINING A CARD; CRYOPYRIN; CYSTEINE PROTEINASE INHIBITOR; HIGH MOBILITY GROUP B1 PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; MUTANT PROTEIN; N (3 PROPYLCARBAMOYLOXIRANE 2 CARBONYL)ISOLEUCYLPROLINE; PATTERN RECOGNITION RECEPTOR; PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; Z VAD FMK;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CELL STIMULATION; CELL VIABILITY; CINCA SYNDROME; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOPLASM; GENE EXPRESSION SYSTEM; GENE MUTATION; GENE SILENCING; IN VIVO STUDY; INFLAMMATION; INNATE IMMUNITY; MALE; MOLECULAR PATHOLOGY; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PYROPTOSIS; UPREGULATION;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; CARRIER PROTEINS; CASPASE 1; CASPASE INHIBITORS; CYTOSKELETAL PROTEINS; DIPEPTIDES; DOXYCYCLINE; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; MICE; NECROSIS; NEUTROPHILS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84879335611     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.169     Document Type: Article

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