Antroquinonol mitigates an accelerated and progressive IgA nephropathy model in mice by activating the Nrf2 pathway and inhibiting T cells and NLRP3 inflammasome

Free Radical Biology and Medicine

Volumn 61, Issue , 2013, Pages 285-297

  Yang, Shun Min ^a   Ka, Shuk Man ^a   Hua, Kuo Feng ^b   Wu, Tzu Hua ^c   Chuang, Yi Ping ^a   Lin, Ya Wen ^a   Yang, Feng Ling ^d   Wu, Shih Hsiung ^d   Yang, Sung Sen ^c   Lin, Shih Hua ^c   Chang, Jia Ming ^e   Chen, Ann ^a,c  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b NATIONAL ILAN UNIVERSITY   (Taiwan)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^d INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^e DEVELOPMENT CENTER FOR BIOTECHNOLOGY   (Taiwan)

Author keywords

Accelerated and progressive IgA; Antroquinonol; Free radicals; Macrophage; nephropathy; NLRP3 inflammasome; Nrf2; ROS; T cell

Indexed keywords

ANTIOXIDANT; ANTROQUINONOL; INFLAMMASOME; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UBIQUINONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; GLOMERULOPATHY; GLOMERULUS; HISTOPATHOLOGY; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOREGULATION; KIDNEY FIBROSIS; KIDNEY FUNCTION; KIDNEY INJURY; LYMPHOCYTE ACTIVATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; T LYMPHOCYTE;

MUS; TAIWANOFUNGUS CAMPHORATUS;

EID: 84877870521     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.03.024     Document Type: Article

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