TGF-β/SMAD3 pathway stimulates sphingosine-1 phosphate receptor 3 expression: Implication of sphingosine-1 phosphate receptor 3 in lung adenocarcinoma progression

Journal of Biological Chemistry

Volumn 291, Issue 53, 2016, Pages 27343-27353

  Zhao, Jiawei ^a   Liu, Jingjing ^a   Lee, Jen Fu ^a   Zhang, Wenliang ^a   Kandouz, Mustapha ^a   VanHecke, Garrett C ^a   Chen, Shiyou ^b   Ahn, Young Hoon ^a   Lonardo, Fulvio ^a   Lee, Menq Jer ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; BINS; CELL CULTURE; CELL SIGNALING; ENZYME ACTIVITY; RESPIRATORY SYSTEM; SPHINGOSINES; TUMORS;

ECTOPIC EXPRESSIONS; HUMAN LUNG ADENOCARCINOMA CELLS; LUCIFERASE REPORTER ASSAYS; LUNG EPITHELIAL CELLS; MEDIATED SIGNALING PATHWAYS; MICROARRAY ANALYSIS; PHARMACOLOGICAL INHIBITION; THERAPEUTIC TARGETS;

BIOLOGICAL ORGANS;

2 AMINO 2 (3 OCTYLPHENYLCARBAMOYL)ETHYL PHOSPHATE; ANTINEOPLASTIC AGENT; SMAD3 PROTEIN; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 3; TRANSFORMING GROWTH FACTOR BETA; TY 52156; UNCLASSIFIED DRUG; MESSENGER RNA; SMAD3 PROTEIN, HUMAN; SPHINGOSINE-1-PHOSPHATE RECEPTOR-3, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CANCER GROWTH; CANCER INHIBITION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA MICROARRAY; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG EPITHELIUM; LUNG METASTASIS; METASTASIS INHIBITION; MICROARRAY ANALYSIS; MOLECULAR INTERACTION; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; UPREGULATION; ADENOCARCINOMA; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; DRUG SCREENING; GENETICS; LUNG; LUNG TUMOR; METABOLISM; NONOBESE DIABETIC MOUSE; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCID MOUSE; SECONDARY; WESTERN BLOTTING;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; FEMALE; HUMANS; LUNG; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, SCID; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, LYSOSPHINGOLIPID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 85007579343     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.740084     Document Type: Article

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