Vitexin suppresses autophagy to induce apoptosis in hepatocellular carcinoma via activation of the JNK signaling pathway

Oncotarget

Volumn 7, Issue 51, 2016, Pages 84520-84532

  He, Jin Dan ^a   Wang, Zhen ^a   Li, Shi Peng ^a,c   Xu, Yan Jie ^a   Yu, Yao ^a   Ding, Yi Jie ^a   Yu, Wen Li ^b   Zhang, Rong Xin ^a   Zhang, Hai Ming ^a,b   Du, Hong Yin ^a,b  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b TIANJIN FIRST CENTRAL HOSPITAL   (China)

^c The People s Hospital of Jiaozuo City   (China)

Author keywords

Apoptosis; Autophagy; Hepatocellular carcinoma; JNK signaling; Vitexin

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; AUTOPHAGY RELATED PROTEIN; CASPASE 3; LC3 2 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; VITEXIN; APIGENIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; AUTOPHAGY SUPPRESSION; CELL VIABILITY; COLONY FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HEPA1 6 CELL LINE; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; MOUSE; MOUSE MODEL; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SK HEP1 CELL LINE; UPREGULATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL SURVIVAL; DRUG EFFECTS; DRUG SCREENING; EXPERIMENTAL LIVER NEOPLASM; LIVER TUMOR; MAPK SIGNALING; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; APIGENIN; APOPTOSIS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEINS; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; LIVER NEOPLASMS; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MAP KINASE SIGNALING SYSTEM; MICE, INBRED C57BL; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 85007478298     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11731     Document Type: Article

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