Purified vitexin compound 1 inhibits growth and angiogenesis through activation of FOXO3a by inactivation of Akt in hepatocellular carcinoma

International Journal of Molecular Medicine

Volumn 33, Issue 2, 2014, Pages 441-448

  Wang, Jiangang ^a   Zheng, Xingxing ^a   Zeng, Guangyao ^a   Zhou, Yingjun ^a   Yuan, Hong ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Akt; Angiogenesis; Forkhead box protein O3a; Hepatocellular carcinoma; Purified vitexin compound 1; Therapeutic action

Indexed keywords

CYCLIN D1; MATRIGEL; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR FKHRL1; VASCULOTROPIN; VITEXIN;

ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CLONOGENIC ASSAY; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; EMBRYO; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; PLANT SEED; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; REGULATOR GENE; SIGNAL TRANSDUCTION; VITEX NEGUNDO; WESTERN BLOTTING;

ANGIOGENESIS INHIBITORS; APIGENIN; CARCINOMA, HEPATOCELLULAR; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; DOWN-REGULATION; FORKHEAD TRANSCRIPTION FACTORS; GENE SILENCING; HEP G2 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIVER NEOPLASMS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84893786347     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2013.1587     Document Type: Article

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