Vitexin 6, a novel lignan, induces autophagy and apoptosis by activating the Jun N-terminal kinase pathway

Anti-Cancer Drugs

Volumn 24, Issue 9, 2013, Pages 928-936

  Zhou, Jun ^a,b   Hu, Huiyong ^c   Long, Jingpei ^a   Wan, Fang ^a   Li, Lili ^a   Zhang, Suzhan ^b   Shi, Yuenian E ^d,e   Chen, Yiding ^a  

^a Zhejiang University School of Medicine   (China)

^b Cancer Institute   (China)

^c Department of Oncology   (China)

^d NANJING MEDICAL UNIVERSITY   (China)

^e FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

apoptosis; autophagy; Jun N terminal kinase pathway; lignan; vitexin

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BECLIN 1; CASPASE 3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; VITEXIN; VITEXIN 6;

APOPTOSIS; ARTICLE; AUTOPHAGY; BLADDER CANCER; BREAST CANCER; CELL CYCLE ARREST; CELL PROLIFERATION; CELL SURVIVAL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IC 50; LEUKEMIA; LIVER CANCER; LUNG CANCER; OSTEOSARCOMA; PANCREAS CANCER; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STOMACH CANCER; UPREGULATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APIGENIN; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DRUGS, CHINESE HERBAL; ETHNOPHARMACOLOGY; HUMANS; INHIBITORY CONCENTRATION 50; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KINETICS; LIGNANS; MAP KINASE SIGNALING SYSTEM; NEOPLASM PROTEINS; NEOPLASMS; PROTEIN KINASE INHIBITORS; SEEDS; VITEX;

EID: 84883340729     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0b013e328364e8d3     Document Type: Article

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