Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline

Experimental Gerontology

Volumn 94, Issue , 2017, Pages 52-58

  Tarantini, Stefano ^a   Tran, Cam Ha T ^b   Gordon, Grant R ^b   Ungvari, Zoltan ^a   Csiszar, Anna ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Cerebral circulation; Cerebrovascular; Functional hyperemia; Geroscience; Microcirculation; Neurovascular coupling; Senescence; Vascular aging; VCI; VCID

Indexed keywords

CYCLOOXYGENASE 1; SOMATOMEDIN C; IGF1 PROTEIN, HUMAN;

ALZHEIMER DISEASE; ASTROCYTE; BRAIN BLOOD FLOW; BRAIN CIRCULATION; CELL AGING; CELL COMMUNICATION; CELL STRUCTURE; COGNITIVE DEFECT; CYTOARCHITECTURE; ENDOTHELIAL DYSFUNCTION; GAIT DISORDER; HUMAN; HYPEREMIA; MICROCIRCULATION; NEUROVASCULAR COUPLING; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; PROTEIN DEFICIENCY; REVIEW; SENESCENCE; VASOCONSTRICTION; AGE; ANIMAL; CALCIUM SIGNALING; COGNITION; COGNITIVE AGING; METABOLISM; PATHOLOGY; PSYCHOLOGY; VASCULAR ENDOTHELIUM;

AGE FACTORS; ALZHEIMER DISEASE; ANIMALS; ASTROCYTES; CALCIUM SIGNALING; CELLULAR SENESCENCE; CEREBROVASCULAR CIRCULATION; COGNITION; COGNITION DISORDERS; COGNITIVE AGING; ENDOTHELIUM, VASCULAR; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MICROCIRCULATION; NEUROVASCULAR COUPLING; OXIDATIVE STRESS;

EID: 85007439916     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2016.11.004     Document Type: Review

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