Purinergic glio-endothelial coupling during neuronal activity: Role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 309, Issue 11, 2015, Pages H1837-H1845

  Toth, Peter ^a,b,c   Tarantini, Stefano ^a   Davila, Antonio ^d   Noa Valcarcel Ares, M ^a   Tucsek, Zsuzsanna ^a,c   Varamini, Behzad ^e   Ballabh, Praveen ^f,g   Sonntag, William E ^a,h   Baur, Joseph A ^d   Csiszar, Anna ^a,c,h   Ungvari, Zoltan ^a,c,h  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF PÉCS   (Hungary)

^c UNIVERSITY OF PÉCS   (Hungary)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e BIOLA UNIVERSITY   (United States)

^f NEW YORK MEDICAL COLLEGE   (United States)

^g WESTCHESTER MEDICAL CENTER   (United States)

^h UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

Astrocyte; Dementia; Endothelial dysfunction; Endothelial nitric oxide synthase; Endothelium; Vascular cognitive impairment

Indexed keywords

2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE; ADENOSINE TRIPHOSPHATE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; PURINERGIC P2Y1 RECEPTOR; ENZYME INHIBITOR; NITRIC OXIDE; NOS3 PROTEIN, MOUSE; P2RY1 PROTEIN, MOUSE; PURINERGIC P2Y RECEPTOR AGONIST; PURINERGIC P2Y RECEPTOR ANTAGONIST;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN BLOOD FLOW; COGNITIVE DEFECT; CONTROLLED STUDY; DEMENTIA; ENDOTHELIUM CELL; HYPEREMIA; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; SOMATOSENSORY CORTEX; VASODILATATION; VIBRISSA; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL COMMUNICATION; DEFICIENCY; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HEMODYNAMICS; HOMEOSTASIS; INNERVATION; KNOCKOUT MOUSE; MECHANOTRANSDUCTION; METABOLISM; MICROCIRCULATION; NEUROVASCULAR COUPLING; PATHOPHYSIOLOGY; VASCULARIZATION;

ANIMALS; ASTROCYTES; CELL COMMUNICATION; ENDOTHELIAL CELLS; ENZYME INHIBITORS; HEMODYNAMICS; HOMEOSTASIS; HYPEREMIA; MECHANOTRANSDUCTION, CELLULAR; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROCIRCULATION; NEUROVASCULAR COUPLING; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PURINERGIC P2Y RECEPTOR AGONISTS; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2Y1; SOMATOSENSORY CORTEX; VIBRISSAE;

EID: 84949257836     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00463.2015     Document Type: Article

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