Effect of non-steroid anti-inflammatory drugs on neurovascular coupling in humans

Journal of the Neurological Sciences

Volumn 336, Issue 1-2, 2014, Pages 227-231

  Szabo, Katalin ^a   Rosengarten, Bernhard ^a   Juhasz, Tunde ^a   Lako, Eva ^a   Csiba, Laszlo ^a   Olah, Laszlo ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Cerebral blood flow; Cerebral vasoconstriction; Neurovascular coupling; Non steroid anti inflammatory drugs; Transcranial Doppler; Visual stimulation

Indexed keywords

INDOMETACIN; NAPROXEN;

ADULT; ARTICLE; BRAIN FUNCTION; CARDIOVASCULAR FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; EVOKED VISUAL RESPONSE; FEMALE; FLOW RATE; HUMAN; MALE; NEUROVASCULAR COUPLING; NORMAL HUMAN; POSTERIOR CEREBRAL ARTERY; PRIORITY JOURNAL; TRANSCRANIAL DOPPLER; VISUAL CORTEX; VISUAL STIMULATION; YOUNG ADULT;

CEREBRAL BLOOD FLOW; CEREBRAL VASOCONSTRICTION; NEUROVASCULAR COUPLING; NON-STEROID ANTI-INFLAMMATORY DRUGS; TRANSCRANIAL DOPPLER; VISUAL STIMULATION;

ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOOD FLOW VELOCITY; CEREBROVASCULAR CIRCULATION; EVOKED POTENTIALS, VISUAL; FEMALE; HUMANS; MALE; PHOTIC STIMULATION; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL; VASOCONSTRICTION; VASODILATION; YOUNG ADULT;

EID: 84892586006     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2013.10.048     Document Type: Article

References (51)

1. C.S. Roy, and C.S. Sherrington On the regulation of the blood supply of the brain J Physiol 11 1890 85 108
2. U. Dirnagl Metabolic aspects of neurovascular coupling Adv Exp Med Biol 413 1997 155 159
3. C. Iadecola Neurovascular regulation in the normal brain and in Alzheimer's disease Nat Rev Neurosci 5 2004 347 360
4. H. Girouard, and C. Iadecola Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease J Appl Physiol 100 2006 328 335
5. R.C. Koehler, D. Gebremedhin, and D.R. Harder Role of astrocytes in cerebrovascular regulation J Appl Physiol 100 2006 307 317
6. J.A. Filosa, and V.M. Blanco Neurovascular coupling in the mammalian brain Exp Physiol 92 2007 641 646
7. R.C. Koehler, R.J. Roman, and D.R. Harder Astrocytes and the regulation of cerebral blood flow Trends Neurosci 32 2009 160 169
8. C. Leithner, G. Royl, N. Offenhauser, M. Füchtemeier, M. Kohl-Bareis, and A. Villringer et al. Pharmacological uncoupling of activation induced increases in CBF and CMRO2 J Cereb Blood Flow Metab 30 2010 311 322
9. J.A. Mitchell, and T.D. Warner COX isoforms in the cardiovascular system: understanding the activities of nonsteroidal anti-inflammatory drugs Nat Rev 5 2006 75 86
10. J.D. Pickard, and E.T. MacKenzie Inhibition of prostaglandin synthesis and the response of baboon cerebral circulation to carbon dioxide Nature 245 1973 187 188
11. T. Sakabe, and B.K. Siesjö The effect of indomethacin on the blood flow-metabolism couple in the brain under normal, hypercapnic and hypoxic conditions Acta Physiol Scand 107 1979 283 284
12. E.S. Gabrielian, E.A. Amroian, and V.I. Megrabian Cerebral blood flow reactions to hypo- and hypercapnia during indomethacin inhibition of prostaglandin biosynthesis Biull Eksp Biol Med 87 1979 240 243
13. J. Pickard, A. Tamura, M. Stewart, A. McGeorge, and W. Fitch Prostacyclin, indomethacin and the cerebral circulation Brain Res 197 1980 425 431
14. W.E. Hoffman, R.F. Albrecht, D. Pelligrino, and D.J. Miletich Effects of prostaglandins on the cerebral circulation in the goat Prostaglandins 23 1982 897 905
15. A. Crockard, F. Iannotti, and G. Ladds Cerebrovascular effects of prostaglandin inhibitors in the gerbil J Cereb Blood Flow Metab 2 1982 67 72
16. A. Wennmalm, S. Eriksson, and J. Wahren Effect of indomethacin on basal and carbon dioxide stimulated cerebral blood flow in man Clin Physiol 1 1981 227 234
17. H. Pickles, M.M. Brown, M. Thomas, A.H. Hewazy, S. Redmond, and E. Zilka et al. Effect of indomethacin on cerebral blood flow, carbon dioxide reactivity and the response to epoprostenol (prostacyclin) infusion in man J Neurol Neurosurg Psychiatry 47 1984 51 55
18. K. Jensen, M. Freundlich, L. Bunemann, K. Therkelsen, H. Hansen, and G.E. Cold The effect of indomethacin upon cerebral blood flow in healthy volunteers: the influence of moderate hypoxia and hypercapnia Acta Neurochir (Wien) 124 1993 114 119
19. K.S. St Lawrence, F.Q. Ye, B.K. Lewis, D.R. Weinberger, J.A. Frank, and A.C. McLaughlin Effects of indomethacin on cerebral blood flow at rest and during hypercapnia: an arterial spin tagging study in humans J Magn Reson Imaging 15 2002 628 635
20. Q. Wang, O.B. Paulson, and N.A. Lassen Indomethacin abolishes cerebral blood flow increase in response to acetazolamide-induced extracellular acidosis: a mechanism for its effect on hypercapnia? J Cereb Blood Flow Metab 13 1993 724 727
21. Q. Wang, J. Bryowsky, R.D. Minshall, and D.A. Pelligrino Possible obligatory functions of cyclic nucleotides in hypercapnia-induced cerebral vasodilation in adult rats Am J Physiol 276 1999 H480 H487
22. K. Csete, P. Barzó, M. Bodosi, and J.G. Papp Influence of nitrovasodilators and cyclooxygenase inhibitors on cerebral vasoreactivity in conscious rabbits Eur J Pharmacol 412 2001 301 309
23. H. Bruhn, P. Fransson, and J. Frahm Modulation of cerebral blood oxygenation by indomethacin: MRI at rest and functional brain activation J Magn Reson Imaging 13 2011 325 334
24. A.D. Edwards, J.S. Wyatt, C. Richardson, A. Potter, M. Cope, and D.T. Delpy et al. Effects of indomethacin on cerebral haemodynamics in very preterm infants Lancet 335 1990 1491 1495
25. C. Hammerman, J. Glaser, M.S. Schimmel, B. Ferber, M. Kaplan, and A.I. Eidelman Continuous versus multiple rapid infusions of indomethacin: effects on cerebral blood flow velocity Pediatrics 95 1995 244 248
26. V. Christmann, K.D. Liem, B.A. Semmekrot, and M. van de Bor Changes in cerebral, renal and mesenteric blood flow velocity during continuous and bolus infusion of indomethacin Acta Paediatr 91 2002 440 446
27. M. Kondo, T. Kunikata, K. Okazaki, S. Yasuda, K. Isobe, and S. Itoh Relation between infusion rate of indomethacin and cerebral blood flow velocity Pediatr Int 52 2010 616 621
28. A.A. Biestro, R.A. Alberti, A.E. Soca, M. Cancela, C.B. Puppo, and B. Borovich Use of indomethacin in brain-injured patients with cerebral perfusion pressure impairment: preliminary report J Neurosurg 83 1995 627 630
29. R. Imberti, M. Fuardo, G. Bellinzona, M. Pagani, and M. Langer The use of indomethacin in the treatment of plateau waves: effects on cerebral perfusion and oxygenation J Neurosurg 102 2005 455 459
30. M. Rasmussen Treatment of elevated intracranial pressure with indomethacin: friend or foe? Acta Anaesthesiol Scand 49 2005 341 350
31. C. Puppo, L. Lopez, G. Farina, E. Caragna, L. Moraes, and A. Iturralde et al. Indomethacin and cerebral autoregulation in severe head injured patients: a transcranial Doppler study Acta Neurochir (Wien) 149 2007 139 149
32. H.S. Markus, P. Vallance, and M.M. Brown Differential effect of three cyclooxygenase inhibitors on human cerebral blood flow velocity and carbon dioxide reactivity Stroke 25 1994 1760 1764
33. B. Rosengarten, C. Aldinger, A. Kaufmann, and M. Kaps Comparison of visually evoked peak systolic and end diastolic blood flow velocity using a control system approach Ultrasound Med Biol 27 2001 1499 1503
34. B. Rosengarten, and M. Kaps Peak systolic velocity Doppler index reflects most appropriately the dynamic time course of intact cerebral autoregulation Cerebrovasc Dis 13 2002 230 234
35. B. Rosengarten, C. Aldinger, A. Spiller, and M. Kaps Neurovascular coupling remains unaffected during normal aging J Neuroimaging 13 2003 43 47
36. K.F. Lindegaard, S.J. Bakke, P. Grolimund, R. Aaslid, P. Huber, and H. Nornes Assessment of intracranial hemodynamics in carotid artery disease by transcranial Doppler ultrasound J Neurosurg 63 1985 890 898
37. A. Pellicer, M. Aparicio, F. Cabañas, E. Valverde, J. Quero, and T.A. Stiris Effect of the cyclo-oxygenase blocker ibuprofen on cerebral blood volume and cerebral blood flow during normocarbia and hypercarbia in newborn piglets Acta Paediatr 88 1999 82 88
38. L.C. Wagerle, and P.A. Degiulio Indomethacin-sensitive CO2 reactivity of cerebral arterioles is restored by vasodilator prostaglandin Am J Physiol 266 1994 H1332 H1338
39. M.M. Bednar, and C.E. Gross Aspirin reduces experimental cerebral blood flow in vivo Neurol Res 21 1999 488 490
40. A. Wennmalm, I. Carlsson, A. Edlund, S. Eriksson, L. Kaijser, and J. Nowak Central and peripheral haemodynamic effects of non-steroidal anti-inflammatory drugs in man Arch Toxicol Suppl 7 1984 350 359
41. S. Chemtob, K. Beharry, T. Barna, D.R. Varma, and J.V. Aranda Differences in the effects in the newborn piglet of various nonsteroidal antiinflammatory drugs on cerebral blood flow but not on cerebrovascular prostaglandins Pediatr Res 30 1991 106 111
42. F.A. Rasulo, E. De Peri, and A. Lavinio Transcranial Doppler ultrasonography in intensive care Eur J Anaesthesiol Suppl 42 2008 167 173
43. V.E. Griffeth, J.E. Perthen, and R.B. Buxton Prospects for quantitative fMRI: investigating the effects of caffeine on baseline oxygen metabolism and the response to a visual stimulus in humans Neuroimage 57 2011 809 816
44. K. Niwa, C. Haensel, M.E. Ross, and C. Iadecola Cyclooxygenase-1 participates in selected vasodilator responses of the cerebral circulation Circ Res 88 2001 600 608
45. K. Niwa, E. Araki, S.G. Morham, M.E. Ross, and C. Iadecola Cyclooxygenase-2 contributes to functional hyperemia in whisker-barrel cortex J Neurosci 20 2000 763 770
46. D. Jakovcevic, and D.R. Harder Role of astrocytes in matching blood flow to neuronal activity Curr Top Dev Biol 79 2007 75 97
47. R.A. Bakalova, T. Matsuura, and I. Kanno Cyclooxygenase-pathway participates in the regulation of regional cerebral blood flow in response to neuronal activation under normo- and hypercapnia Prostaglandins Leukot Essent Fatty Acids 67 2002 379 388
48. B. Stefanovic, F. Bosetti, and A.C. Silva Modulatory role of cyclooxygenase-2 in cerebrovascular coupling Neuroimage 32 2006 23 32
49. T. Matsuura, H. Takuwa, R. Bakalova, T. Obata, and I. Kanno Effect of cyclooxygenase-2 on the regulation of cerebral blood flow during neuronal activation in the rat Neurosci Res 65 2009 64 70
50. T. Hahn, S. Heinzel, M.M. Plichta, A. Reif, K.P. Lesch, and A.J. Fallgatter Neurovascular coupling in the human visual cortex is modulated by cyclooxygenase-1 (COX-1) gene variant Cereb Cortex 21 2011 1659 1666
51. R. Mirro, C.W. Leffler, W. Armstead, D.G. Beasley, and D.W. Busija Indomethacin restricts cerebral blood flow during pressure ventilation of newborn pigs Pediatr Res 24 1988 59 62