A critical role for purinergic signalling in the mechanisms underlying generation of BOLD fMRI responses

Journal of Neuroscience

Volumn 35, Issue 13, 2015, Pages 5284-5292

  Wells, Jack A ^a   Christie, Isabel N ^a,b   Hosford, Patrick S ^b   Huckstepp, Robert T R ^b   Angelova, Plamena R ^c   Vihko, Pirkko ^d   Cork, Simon C ^b   Abramov, Andrey Y ^c   Teschemacher, Anja G ^e   Kasparov, Sergey ^e   Lythgoe, Mark F ^a   Gourine, Alexander V ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF HELSINKI   (Finland)

^e UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Astrocyte; ATP; BOLD; fMRI; Glia; Neurovascular coupling

Indexed keywords

ACID PHOSPHATASE PROSTATE ISOENZYME; ADENOSINE; ADENOSINE TRIPHOSPHATE; LENTIVIRUS VECTOR; ACID PHOSPHATASE; ADENOSINE RECEPTOR BLOCKING AGENT; PROTEIN TYROSINE PHOSPHATASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BOLD SIGNAL; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; BRAIN ELECTROPHYSIOLOGY; FOREFOOT; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENE OVEREXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; NERVE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PURINERGIC SIGNALING; RAT; SIGNAL TRANSDUCTION; SOMATOSENSORY CORTEX; VIRAL GENE DELIVERY SYSTEM; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN CIRCULATION; DRUG EFFECTS; ELECTROSTIMULATION; FORELIMB; FUNCTIONAL NEUROIMAGING; GENETICS; METABOLISM; MICROINJECTION; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSIOLOGY; VASCULARIZATION;

ACID PHOSPHATASE; ADENOSINE TRIPHOSPHATE; ANIMALS; CEREBROVASCULAR CIRCULATION; ELECTRIC STIMULATION; FORELIMB; FUNCTIONAL NEUROIMAGING; MAGNETIC RESONANCE IMAGING; MALE; MICROINJECTIONS; PROTEIN TYROSINE PHOSPHATASES; PURINERGIC P1 RECEPTOR ANTAGONISTS; RATS; SIGNAL TRANSDUCTION; SOMATOSENSORY CORTEX;

EID: 84929340056     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3787-14.2015     Document Type: Article

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