Liver X receptors agonists suppress NLRP3 inflammasome activation

Cytokine

Volumn 91, Issue , 2017, Pages 30-37

  Yu, Shui Xing ^a   Chen, Wei ^a   Hu, Xiao Zhu ^a   Feng, Shi Yuan ^a   Li, Kun Yu ^a   Qi, Shuai ^a   Lei, Qian Qian ^a   Hu, Gui Qiu ^a   Li, Ning ^a   Zhou, Feng Hua ^a   Ma, Chao Ying ^a   Du, Chong Tao ^a   Yang, Yong Jun ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

Inflammasome; Inflammation; LXRs agonists; mtROS; NLRP3

Indexed keywords

CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIVER X RECEPTOR AGONIST; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; MESSENGER RNA; MITOCHONDRIAL REACTIVE OXYGEN SPECIES; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CASP3 PROTEIN, MOUSE; CASPASE 3; IL1B PROTEIN, MOUSE; LIVER X RECEPTOR; NLRP3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG MECHANISM; GENE SILENCING; IN VIVO STUDY; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OLIGOMERIZATION; OXIDATIVE STRESS; PERITONITIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; AGONISTS; ANIMAL; CELL LINE; DRUG EFFECTS; IMMUNOLOGY; PATHOLOGY;

ANIMALS; CASPASE 3; CELL LINE; INFLAMMASOMES; INTERLEUKIN-1BETA; LIVER X RECEPTORS; MICE; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PERITONITIS; SIGNAL TRANSDUCTION;

EID: 85006056586     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2016.12.003     Document Type: Article

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