LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling

eLife

Volumn 4, Issue JULY 2015, 2015, Pages

  Ito, Ayaka ^a   Hong, Cynthia ^a   Rong, Xin ^a   Zhu, Xuewei ^b   Tarling, Elizabeth J ^a   Hedde, Per Niklas ^c   Gratton, Enrico ^c   Parks, John ^b   Tontonoz, Peter ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; CHOLESTEROL; LIVER X RECEPTOR; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR; ABCA1 PROTEIN, MOUSE; ORPHAN NUCLEAR RECEPTOR;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOLOGICAL FUNCTIONS; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME REPRESSION; FLOW CYTOMETRY; GENE ACTIVATION; GENE OVEREXPRESSION; IMMUNE RESPONSE; IMMUNOFLUORESCENCE MICROSCOPY; INFLAMMATION; LIPID HOMEOSTASIS; LIPID METABOLISM; LIVER METABOLISM; MACROPHAGE; METABOLIC REGULATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SUMOYLATION; TRANSCRIPTION INITIATION; ANIMAL; CELL CULTURE; CELL MEMBRANE; CHEMISTRY; GENE EXPRESSION PROFILING; METABOLISM;

MUS;

ANIMALS; ATP BINDING CASSETTE TRANSPORTER 1; CELL MEMBRANE; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; GENE EXPRESSION PROFILING; INFLAMMATION; LIVER X RECEPTORS; MICE; ORPHAN NUCLEAR RECEPTORS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84938335974     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.08009     Document Type: Article

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