FcγR mediates TLR2- and Syk-dependent NLRP3 inflammasome activation by inactivated Francisella tularensis LVS immune complexes

Journal of Leukocyte Biology

Volumn 100, Issue 6, 2016, Pages 1335-1347

  Duffy, Ellen B ^a,b   Periasamy, Sivakumar ^a   Hunt, Danielle ^a   Drake, James R ^a   Harton, Jonathan A ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

^b Touro University College of Pharmacy and School of Osteopathic Medicine   (United States)

Author keywords

IL 1 ; Macrophage; Vaccine

Indexed keywords

CASPASE 8; CRYOPYRIN; FC RECEPTOR; IMMUNOGLOBULIN A; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIVE VACCINE; MONOCLONAL ANTIBODY; PROTEIN KINASE SYK; TOLL LIKE RECEPTOR 2; ANTIGEN ANTIBODY COMPLEX; BACTERIAL ANTIGEN; BACTERIAL VACCINE; BACTERIUM ANTIBODY; CASP8 PROTEIN, HUMAN; CASP8 PROTEIN, MOUSE; NLRP3 PROTEIN, HUMAN; NLRP3 PROTEIN, MOUSE; SYK PROTEIN, HUMAN; SYK PROTEIN, MOUSE; TLR2 PROTEIN, HUMAN; TLR2 PROTEIN, MOUSE;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DENDRITIC CELL; FEMALE; FRANCISELLA TULARENSIS; HUMAN; HUMAN CELL; MACROPHAGE; MALE; MELANOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; VACCINATION; WILD TYPE MOUSE; ANIMAL; C57BL MOUSE; CELL LINE; DEFICIENCY; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MONOCYTE; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, BACTERIAL; BACTERIAL VACCINES; CASPASE 8; CELL LINE; DENDRITIC CELLS; FRANCISELLA TULARENSIS; INFLAMMASOMES; INTERLEUKIN-1BETA; MACROPHAGES; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; RECEPTORS, IGG; SIGNAL TRANSDUCTION; SYK KINASE; TOLL-LIKE RECEPTOR 2; VACCINATION;

EID: 85002736887     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.2A1215-555RR     Document Type: Article

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