-
2
-
-
27944463947
-
Lack of antigen-specific Th1 response alters granuloma formation and composition in Schistosoma mansoni-infected MyD88-/- mice
-
Layland LE, Wagner H, da Costa CU (2005) Lack of antigen-specific Th1 response alters granuloma formation and composition in Schistosoma mansoni-infected MyD88-/- mice. Eur J Immunol 35:3248-3257.
-
(2005)
Eur J Immunol
, vol.35
, pp. 3248-3257
-
-
Layland, L.E.1
Wagner, H.2
Da Costa, C.U.3
-
3
-
-
0026060650
-
Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni
-
Pearce EJ, Caspar P, Grzych JM, Lewis FA, Sher A (1991) Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J Exp Med 173:159-166.
-
(1991)
J Exp Med
, vol.173
, pp. 159-166
-
-
Pearce, E.J.1
Caspar, P.2
Grzych, J.M.3
Lewis, F.A.4
Sher, A.5
-
4
-
-
0029142790
-
An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection
-
Wynn TA, et al. (1995) An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection. Nature 376:594-596.
-
(1995)
Nature
, vol.376
, pp. 594-596
-
-
Wynn, T.A.1
-
5
-
-
0032824435
-
TNF is essential for the cell-mediated protective immunity induced by the radiation-attenuated schistosome vaccine
-
Street M, et al. (1999) TNF is essential for the cell-mediated protective immunity induced by the radiation-attenuated schistosome vaccine. J Immunol 163:4489-4494.
-
(1999)
J Immunol
, vol.163
, pp. 4489-4494
-
-
Street, M.1
-
6
-
-
33846918192
-
Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation
-
van Liempt E, et al. (2007) Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation. Mol Immunol 44:2605-2615.
-
(2007)
Mol Immunol
, vol.44
, pp. 2605-2615
-
-
Van Liempt, E.1
-
7
-
-
26244436368
-
Schistosome larvae stimulate macrophage cytokine production through TLR4-dependent and -independent pathways
-
Jenkins SJ, Hewitson JP, Ferret-Bernard S, Mountford AP (2005) Schistosome larvae stimulate macrophage cytokine production through TLR4-dependent and -independent pathways. Int Immunol 17:1409-1418.
-
(2005)
Int Immunol
, vol.17
, pp. 1409-1418
-
-
Jenkins, S.J.1
Hewitson, J.P.2
Ferret-Bernard, S.3
Mountford, A.P.4
-
8
-
-
0026554818
-
Tumour necrosis factor alpha restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice
-
Amiri P, et al. (1992) Tumour necrosis factor alpha restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice. Nature 356:604-607.
-
(1992)
Nature
, vol.356
, pp. 604-607
-
-
Amiri, P.1
-
9
-
-
0037100279
-
Cytokine regulation of periportal fibrosis in humans infected with Schistosoma mansoni: IFN-γ is associated with protection against fibrosis and TNF-A with aggravation of disease
-
Henri S, et al. (2002) Cytokine regulation of periportal fibrosis in humans infected with Schistosoma mansoni: IFN-γ is associated with protection against fibrosis and TNF-a with aggravation of disease. J Immunol 169:929-936.
-
(2002)
J Immunol
, vol.169
, pp. 929-936
-
-
Henri, S.1
-
10
-
-
77954161382
-
Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms
-
Correale J, Farez M (2009) Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms. J Immunol 183:5999-6012.
-
(2009)
J Immunol
, vol.183
, pp. 5999-6012
-
-
Correale, J.1
Farez, M.2
-
11
-
-
10344252794
-
Helminth antigens modulate TLR-initiated dendritic cell activation
-
Kane CM, et al. (2004) Helminth antigens modulate TLR-initiated dendritic cell activation. J Immunol 173:7454-7461.
-
(2004)
J Immunol
, vol.173
, pp. 7454-7461
-
-
Kane, C.M.1
-
12
-
-
0027179695
-
Endogenous IL-1 receptor antagonist protein (IRAP) regulates schistosome egg granuloma formation and the regional lymphoid response
-
Chensue SW, et al. (1993) Endogenous IL-1 receptor antagonist protein (IRAP) regulates schistosome egg granuloma formation and the regional lymphoid response. J Immunol 151:3654-3662.
-
(1993)
J Immunol
, vol.151
, pp. 3654-3662
-
-
Chensue, S.W.1
-
13
-
-
0029881638
-
IL-1 receptor antagonist (IL-1ra) expression, function, and cytokine-mediated regulation during mycobacterial and schistosomal antigen-elicited granuloma formation
-
Ruth JH, et al. (1996) IL-1 receptor antagonist (IL-1ra) expression, function, and cytokine-mediated regulation during mycobacterial and schistosomal antigen-elicited granuloma formation. J Immunol 156:2503-2509.
-
(1996)
J Immunol
, vol.156
, pp. 2503-2509
-
-
Ruth, J.H.1
-
14
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 β processing in monocytes
-
Thornberry NA, et al. (1992) A novel heterodimeric cysteine protease is required for interleukin-1 β processing in monocytes. Nature 356:768-774.
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
-
15
-
-
33845497181
-
Inflammatory caspases and inflammasomes: Master switches of inflammation
-
Martinon F, Tschopp J (2007) Inflammatory caspases and inflammasomes: Master switches of inflammation. Cell Death Differ 14:10-22.
-
(2007)
Cell Death Differ
, vol.14
, pp. 10-22
-
-
Martinon, F.1
Tschopp, J.2
-
16
-
-
50849119416
-
The caspase-1 inflammasome: A pilot of innate immune responses
-
Yu HB, Finlay BB (2008) The caspase-1 inflammasome: A pilot of innate immune responses. Cell Host Microbe 4:198-208.
-
(2008)
Cell Host Microbe
, vol.4
, pp. 198-208
-
-
Yu, H.B.1
Finlay, B.B.2
-
17
-
-
0028175838
-
Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity
-
Perregaux D, Gabel CA (1994) Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity. J Biol Chem 269:15195-15203.
-
(1994)
J Biol Chem
, vol.269
, pp. 15195-15203
-
-
Perregaux, D.1
Gabel, C.A.2
-
18
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Pétrilli V, Mayor A, Tardivel A, Tschopp J (2006) Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440:237-241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Pétrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
19
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
Dostert C, et al. (2008) Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320:674-677.
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
-
20
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA (2008) Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453:1122-1126.
-
(2008)
Nature
, vol.453
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor, W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
21
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
Halle A, et al. (2008) The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol 9:857-865.
-
(2008)
Nat Immunol
, vol.9
, pp. 857-865
-
-
Halle, A.1
-
22
-
-
67349271142
-
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
-
Gross O, et al. (2009) Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature 459:433-436.
-
(2009)
Nature
, vol.459
, pp. 433-436
-
-
Gross, O.1
-
23
-
-
68349157477
-
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
-
Dostert CG, et al. (2009) Malarial hemozoin is a Nalp3 inflammasome activating danger signal. PLoS ONE 4:e6510.
-
(2009)
PLoS ONE
, vol.4
-
-
Dostert, C.G.1
-
24
-
-
0029916522
-
Mice deficient in IL-1β manifest impaired contact hypersensitivity to trinitrochlorobenzone
-
Shornick LP, et al. (1996) Mice deficient in IL-1β manifest impaired contact hypersensitivity to trinitrochlorobenzone. J Exp Med 183:1427-1436.
-
(1996)
J Exp Med
, vol.183
, pp. 1427-1436
-
-
Shornick, L.P.1
-
25
-
-
0029979369
-
Biologic basis for interleukin-1 in disease
-
Dinarello CA (1996) Biologic basis for interleukin-1 in disease. Blood 87:2095-2147.
-
(1996)
Blood
, vol.87
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
26
-
-
0035916324
-
The pyrin domain: A possible member of the death domain-fold family implicated in apoptosis and inflammation
-
Martinon F, Hofmann K, Tschopp J (2001) The pyrin domain: A possible member of the death domain-fold family implicated in apoptosis and inflammation. Curr Biol 11: 118-120.
-
(2001)
Curr Biol
, vol.11
, pp. 118-120
-
-
Martinon, F.1
Hofmann, K.2
Tschopp, J.3
-
28
-
-
68149156007
-
Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses
-
Everts B, et al. (2009) Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses. J Exp Med 206:1673-1680.
-
(2009)
J Exp Med
, vol.206
, pp. 1673-1680
-
-
Everts, B.1
-
29
-
-
68149163162
-
The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)
-
Steinfelder S, et al. (2009) The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1). J Exp Med 206:1681-1690.
-
(2009)
J Exp Med
, vol.206
, pp. 1681-1690
-
-
Steinfelder, S.1
-
30
-
-
0029665112
-
The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7
-
Surprenant A, Rassendren F, Kawashima E, North RA, Buell G (1996) The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 272: 735-738.
-
(1996)
Science
, vol.272
, pp. 735-738
-
-
Surprenant, A.1
Rassendren, F.2
Kawashima, E.3
North, R.A.4
Buell, G.5
-
31
-
-
33751197936
-
R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation
-
Braselmann S, et al. (2006) R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation. J Pharmacol Exp Ther 319:998-1008.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 998-1008
-
-
Braselmann, S.1
-
32
-
-
33847418504
-
Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells
-
Goodridge HS, Simmons RM, Underhill DM (2007) Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells. J Immunol 178:3107-3115.
-
(2007)
J Immunol
, vol.178
, pp. 3107-3115
-
-
Goodridge, H.S.1
Simmons, R.M.2
Underhill, D.M.3
-
33
-
-
33845977385
-
Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor γ chain to induce innate immune responses
-
Sato K, et al. (2006) Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor γ chain to induce innate immune responses. J Biol Chem 281: 38854-38866.
-
(2006)
J Biol Chem
, vol.281
, pp. 38854-38866
-
-
Sato, K.1
-
34
-
-
69549108298
-
Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection
-
Robinson MJ, et al. (2009) Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection. J Exp Med 206:2037-2051.
-
(2009)
J Exp Med
, vol.206
, pp. 2037-2051
-
-
Robinson, M.J.1
-
35
-
-
50649113319
-
Dendritic cell interaction with Candida albicans critically depends on N-linked mannan
-
Cambi A, et al. (2008) Dendritic cell interaction with Candida albicans critically depends on N-linked mannan. J Biol Chem 283:20590-20599.
-
(2008)
J Biol Chem
, vol.283
, pp. 20590-20599
-
-
Cambi, A.1
-
36
-
-
69449106110
-
IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells
-
Guo L, et al. (2009) IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells. Proc Natl Acad Sci USA 106:13463-13468.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 13463-13468
-
-
Guo, L.1
-
37
-
-
70349263475
-
Genetic control of severe egg-induced immunopathology and IL-17 production in murine schistosomiasis
-
Smith PM, et al. (2009) Genetic control of severe egg-induced immunopathology and IL-17 production in murine schistosomiasis. J Immunol 183:3317-3323.
-
(2009)
J Immunol
, vol.183
, pp. 3317-3323
-
-
Smith, P.M.1
-
38
-
-
70350007738
-
Transforming growth factor-β and Th17 responses in resistance to primary murine schistosomiasis mansoni
-
Tallima H, Salah M, Guirguis FR, El Ridi R (2009) Transforming growth factor-β and Th17 responses in resistance to primary murine schistosomiasis mansoni. Cytokine 48: 239-245.
-
(2009)
Cytokine
, vol.48
, pp. 239-245
-
-
Tallima, H.1
Salah, M.2
Guirguis, F.R.3
El Ridi, R.4
|