Dynamic pre-BCR homodimers fine-tune autonomous survival signals in B cell precursor acute lymphoblastic leukemia

Science Signaling

Volumn 9, Issue 456, 2016, Pages

  Erasmus, M Frank ^a,b   Matlawska Wasowska, Ksenia ^a,b   Kinjyo, Ichiko ^a,b   Mahajan, Avanika ^a,b   Winter, Stuart S ^a,b   Xu, Li ^c   Horowitz, Michael ^c   Lidke, Diane S ^a,b   Wilson, Bridget S ^a,b  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

^c Sea Lane Biotechnologies ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD79B ANTIGEN; GALECTIN 1; HOMODIMER; MESSENGER RNA; PRE B CELL RECEPTOR; PROTEIN BCL 6; PROTEIN KINASE LYN; PROTEIN KINASE SYK; QUANTUM DOT; SH2 DOMAIN CONTAINING INOSITOL 5' PHOSPHATASE 1 PROTEIN; SURROGATE IMMUNOGLOBULIN LIGHT CHAIN; SURROGATE IMMUNOGLOBULIN LIGHT CHAIN LAMBDA 5; UNCLASSIFIED DRUG; BCL6 PROTEIN, HUMAN; LYN PROTEIN-TYROSINE KINASE; PROTEIN TYROSINE KINASE; SYK PROTEIN, HUMAN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTIGEN BINDING; APOPTOSIS; ARTICLE; BINDING SITE; CELL MEMBRANE; CELL SURVIVAL; CONTROLLED STUDY; DIMERIZATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LECTIN BINDING SITE; MOLECULAR DYNAMICS; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; IMMUNOLOGY; PATHOLOGY; PROTEIN MULTIMERIZATION; TUMOR CELL LINE;

CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; PRE-B CELL RECEPTORS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PRECURSOR CELLS, B-LYMPHOID; PROTEIN MULTIMERIZATION; PROTO-ONCOGENE PROTEINS C-BCL-6; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; SYK KINASE;

EID: 85002187690     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aaf3949     Document Type: Article

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