Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor

Nature Communications

Volumn 6, Issue , 2015, Pages

  Freeman, Spencer A ^a,b   Jaumouillé, Valentin ^b   Choi, Kate ^a   Hsu, Brian E ^a   Wong, Harikesh S ^b   Abraham, Libin ^a   Graves, Marcia L ^a   Coombs, Daniel ^a   Roskelley, Calvin D ^a   Das, Raibatak ^c   Grinstein, Sergio ^b   Gold, Michael R ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; B CELL ACTIVATING FACTOR; B LYMPHOCYTE ANTIGEN; B LYMPHOCYTE RECEPTOR; COFILIN; F ACTIN; G ACTIN; LIGAND; METHYL CPG BINDING PROTEIN; TOLL LIKE RECEPTOR; LIPOPOLYSACCHARIDE; LYMPHOCYTE ANTIGEN RECEPTOR;

ANTIGEN; CELLS AND CELL COMPONENTS; LIGAND; LIPID; MOBILITY; PHYSIOLOGICAL RESPONSE; POLYSACCHARIDE; PROTEIN;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ANIMAL CELL; ANTIGEN BINDING; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL MEMBRANE; CELL MOTILITY; CELL SURFACE; CONTROLLED STUDY; CROSS LINKING; LIGHT CHAIN; MOUSE; NONHUMAN; PROTEIN DEPHOSPHORYLATION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CONFOCAL MICROSCOPY; IMMUNOBLOTTING; METABOLISM; PHYSIOLOGY;

ACTINS; ANIMALS; IMMUNOBLOTTING; LIGANDS; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84955314947     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7168     Document Type: Article

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