Clonidine preconditioning alleviated focal cerebral ischemic insult in rats via up-regulating p-NMDAR1 and down-regulating NMDAR2A / p-NMDAR2B

European Journal of Pharmacology

Volumn 793, Issue , 2016, Pages 89-94

  Yanli, Li ^a   Xizhou, Zhang ^b   Yan, Wang ^c   Bo, Zhao ^a   Yunhong, Zha ^b   Zicheng, Li ^a   Lingling, Yu ^a   lingling, Yan ^d   Zhangao, Chen ^e   Min, Zheng ^f   Zhi, He ^a  

^a CHINA THREE GORGES UNIVERSITY   (China)

^b First Renmin Hospital of Yichang   (China)

^c THE FIRST PEOPLE S HOSPITAL OF FOSHAN   (China)

^d WUHAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^e Biomedical Technology Co LTD   (China)

^f HUBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Cerebral ischemia; Clonidine; NMDAR1; NMDAR2A; NMDAR2B

Indexed keywords

CLONIDINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; YOHIMBINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NMDA RECEPTOR A1; NR2B NMDA RECEPTOR;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN EDEMA; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROLOGIC DISEASE ASSESSMENT; NEUROLOGICAL DEFICIT SCORE; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; REPERFUSION; UPREGULATION; ANIMAL; COMPLICATION; DRUG EFFECTS; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC PRECONDITIONING; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN EDEMA; CLONIDINE; DOWN-REGULATION; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC PRECONDITIONING; MALE; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 85000417224     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2016.10.036     Document Type: Article

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