Neuroprotective effects of oxymatrine against excitotoxicity partially through down-regulation of NR2B-containing NMDA receptors

Phytomedicine

Volumn 20, Issue 3-4, 2013, Pages 343-350

  Zhang, Kun ^a   Li, Yu Jiao ^a   Yang, Qi ^a   Gerile, Oudeng ^a   Yang, Le ^a   Li, Xu Bo ^a   Guo, Yan Yan ^a   Zhang, Nan ^a   Feng, Bin ^a   Liu, Shui Bing ^a   Zhao, Ming Gao ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Middle cerebral artery occlusion; N methyl d aspartate; Neuron; Oxymatrine

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; OXYMATRINE; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; EXCITOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL; NERVE CELL CULTURE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REPERFUSION INJURY; WESTERN BLOTTING;

ALKALOIDS; ANIMALS; BCL-2-ASSOCIATED X PROTEIN; BRAIN ISCHEMIA; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; DRUGS, CHINESE HERBAL; MALE; MICE; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PHYTOTHERAPY; PROTO-ONCOGENE PROTEINS C-BCL-2; QUINOLIZINES; RECEPTORS, N-METHYL-D-ASPARTATE; REPERFUSION INJURY; SOPHORA;

MUS; SOPHORA FLAVESCENS;

EID: 84873702478     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2012.10.018     Document Type: Article

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