-
1
-
-
0027340385
-
Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts
-
Alblas, J., van Corven, E.J., Hordijk, P.L., Milligan, G., Moolenaar, W.H. (1993) Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts. J. Biol. Chem., 268, 22235-22238.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 22235-22238
-
-
Alblas, J.1
van Corven, E.J.2
Hordijk, P.L.3
Milligan, G.4
Moolenaar, W.H.5
-
2
-
-
0023930519
-
Ultrastructural features of a brain injury model in cat. I. Vascular and neuroglial changes and the prevention of astroglial swelling by a fluorenyl (aryloxy) alkanoic acid derivative (L-644,71 1)
-
Barron, K.D., Dentinger, M.P., Kimelberg, H.K., Nelson, L.R., Bourke, R.S., Keegan, S., Mankes, R., Cragoe, E.J. (1988) Ultrastructural features of a brain injury model in cat. I. Vascular and neuroglial changes and the prevention of astroglial swelling by a fluorenyl (aryloxy) alkanoic acid derivative (L-644,71 1). Acta Neuropathol (Berl.), 75, 295-307.
-
(1988)
Acta Neuropathol (Berl.)
, vol.75
, pp. 295-307
-
-
Barron, K.D.1
Dentinger, M.P.2
Kimelberg, H.K.3
Nelson, L.R.4
Bourke, R.S.5
Keegan, S.6
Mankes, R.7
Cragoe, E.J.8
-
3
-
-
0032169760
-
Tizanidine is an effective agent in the prevention of focal cerebral ischemia in rats: An experimental study
-
Berkman, M.Z., Zirh, T.A., Berkman, K., Pamir, M.N. (1998) Tizanidine is an effective agent in the prevention of focal cerebral ischemia in rats: An experimental study. Surg. Neurol., 50, 264-271.
-
(1998)
Surg. Neurol.
, vol.50
, pp. 264-271
-
-
Berkman, M.Z.1
Zirh, T.A.2
Berkman, K.3
Pamir, M.N.4
-
4
-
-
0033198406
-
Presynaptic alpha2-adrenoceptors control excitatory, but not inhibitory, transmission at rat hippocampal synapses
-
Boehm, S. (1999) Presynaptic alpha2-adrenoceptors control excitatory, but not inhibitory, transmission at rat hippocampal synapses. J. Physiol. (Lond.), 519, 439-449.
-
(1999)
J. Physiol. (Lond.)
, vol.519
, pp. 439-449
-
-
Boehm, S.1
-
5
-
-
0027463668
-
Heterogeneity of the specific imidazoline binding of [3H]idazoxan in the human cerebral cortex
-
Bricca, G., Greney, H., Dontenwill-Kieffer, M., Zhang, J., Belcourt, A., Bousquet, P. (1993) Heterogeneity of the specific imidazoline binding of [3H]idazoxan in the human cerebral cortex. Neurochem. Int., 22, 153-63.
-
(1993)
Neurochem. Int.
, vol.22
, pp. 153-163
-
-
Bricca, G.1
Greney, H.2
Dontenwill-Kieffer, M.3
Zhang, J.4
Belcourt, A.5
Bousquet, P.6
-
6
-
-
0028174145
-
Human brain imidazoline receptors: Further characterization with [3H]clonidine
-
Bricca, G., Greney, H., Zhang, J., Dontenwill, M., Stutzmann, J., Belcourt, A., Bousquet, P. (1994) Human brain imidazoline receptors: further characterization with [3H]clonidine. Eur. J. Pharmacol., 266, 25-33.
-
(1994)
Eur. J. Pharmacol.
, vol.266
, pp. 25-33
-
-
Bricca, G.1
Greney, H.2
Zhang, J.3
Dontenwill, M.4
Stutzmann, J.5
Belcourt, A.6
Bousquet, P.7
-
7
-
-
0028183015
-
International Union of Pharmacology Nomenclature on adrenoceptors
-
Bylund, D.B., Eikenburg, D.C., Hieble, J.P., Langer, S.Z., Lefkowitz, R.J., Minneman, K.P., Molinoff, P.B., Ruffolo, R.R., Trendelenburg, U. (1994) International Union of Pharmacology Nomenclature on adrenoceptors. Pharmacol. Rev., 46, 121-136.
-
(1994)
Pharmacol. Rev.
, vol.46
, pp. 121-136
-
-
Bylund, D.B.1
Eikenburg, D.C.2
Hieble, J.P.3
Langer, S.Z.4
Lefkowitz, R.J.5
Minneman, K.P.6
Molinoff, P.B.7
Ruffolo, R.R.8
Trendelenburg, U.9
-
8
-
-
0024331650
-
α2A and α2B adrenergic receptor subtypes: Attenuation of cyclic AMP production in cell lines containing only one receptor type
-
Bylund, D.B., Ray-Prenger, C. (1989) α2A and α2B adrenergic receptor subtypes: attenuation of cyclic AMP production in cell lines containing only one receptor type. J. Pharmacol. Exp. Ther., 251, 640-644.
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.251
, pp. 640-644
-
-
Bylund, D.B.1
Ray-Prenger, C.2
-
9
-
-
0032586829
-
Alpha2A- but not alpha2B/C-adrenoceptors modulate noradrenaline release in rat locus coeruleus: Voltammetric data
-
Callado, L.F., Stamford, J.A. (1999) Alpha2A- but not alpha2B/C-adrenoceptors modulate noradrenaline release in rat locus coeruleus: voltammetric data. Eur. J. Pharmacol., 366, 35-39.
-
(1999)
Eur. J. Pharmacol.
, vol.366
, pp. 35-39
-
-
Callado, L.F.1
Stamford, J.A.2
-
10
-
-
0028815015
-
Inhibition of amine oxidase activity by derivatives that recognize imidazoline I2 sites
-
Carpene, C., Collon, P., Remaury, A., Cordi, A., Hudson, A., Nutt, D., Lafontan, M. (1995) Inhibition of amine oxidase activity by derivatives that recognize imidazoline I2 sites. J. Pharmacol. Exp. Ther., 272, 681-688.
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.272
, pp. 681-688
-
-
Carpene, C.1
Collon, P.2
Remaury, A.3
Cordi, A.4
Hudson, A.5
Nutt, D.6
Lafontan, M.7
-
11
-
-
0025686271
-
Limitations of in vitro models of ischemia
-
Choi, D.W. (1990) Limitations of in vitro models of ischemia. Prog. Clin. Biol. Res,, 361, 291-9.
-
(1990)
Prog. Clin. Biol. Res.
, vol.361
, pp. 291-299
-
-
Choi, D.W.1
-
12
-
-
0025156752
-
Imidazoline-guanidium receptive site in renal proximal tubule: Asymmetric distribution, regulation by cations and interaction with an endogenous clonidine displacing substance
-
Coupry, I., Atlas, D., Podevin, R.A., Uzielli, I., Parini, A. (1989) Imidazoline-guanidium receptive site in renal proximal tubule: asymmetric distribution, regulation by cations and interaction with an endogenous clonidine displacing substance. J. Pharmacol. Exp. Ther., 252, 293-299
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.252
, pp. 293-299
-
-
Coupry, I.1
Atlas, D.2
Podevin, R.A.3
Uzielli, I.4
Parini, A.5
-
13
-
-
0031593630
-
Subtypes of functional alphal- and alpha2-adrenoceptors
-
Docherty, J.R. (1998) Subtypes of functional alphal- and alpha2-adrenoceptors. Eur. J. Pharmacol., 361, 1-15.
-
(1998)
Eur. J. Pharmacol.
, vol.361
, pp. 1-15
-
-
Docherty, J.R.1
-
14
-
-
0035198185
-
Alpha(2)-Adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemia
-
Donello, J.E., Padillo, E.U., Webster, M.L., Wheeler, L.A., Gil, D.W. (2001) alpha(2)-Adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemia. J. Pharmacol. Exp. Ther., 296, 216-23.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.296
, pp. 216-223
-
-
Donello, J.E.1
Padillo, E.U.2
Webster, M.L.3
Wheeler, L.A.4
Gil, D.W.5
-
15
-
-
0029780058
-
2 adrenergic agonists for regional anesthesia: A clinical review of clonidine (1984-1995)
-
2 adrenergic agonists for regional anesthesia: A clinical review of clonidine (1984-1995). Anesthesiology, 86, 655-674.
-
(1996)
Anesthesiology
, vol.86
, pp. 655-674
-
-
Eisenach, J.C.1
Dekoock, M.2
Klimscha, W.3
-
16
-
-
0037302813
-
The effect of the alpha 2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats
-
Engelhard, K., Werner, C., Eberspacher, E., Bachl, M., Blobner, M., Hildt, E., Hutzler, P., Kochs, E. (2003) The effect of the alpha 2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats. Anesth. Analg., 96, 524-531.
-
(2003)
Anesth. Analg.
, vol.96
, pp. 524-531
-
-
Engelhard, K.1
Werner, C.2
Eberspacher, E.3
Bachl, M.4
Blobner, M.5
Hildt, E.6
Hutzler, P.7
Kochs, E.8
-
17
-
-
0036007571
-
Effect of the alpha2-agonist dexmedetomidine on cerebral neurotransmitter concentrations during cerebral ischemia in rats
-
Engelhard, K., Werner, C., Kaspar, S., Mollenberg, O., Blobner, M., Bachl, M., Kochs, E. (2002) Effect of the alpha2-agonist dexmedetomidine on cerebral neurotransmitter concentrations during cerebral ischemia in rats. Anesthesiology, 96, 450-457.
-
(2002)
Anesthesiology
, vol.96
, pp. 450-457
-
-
Engelhard, K.1
Werner, C.2
Kaspar, S.3
Mollenberg, O.4
Blobner, M.5
Bachl, M.6
Kochs, E.7
-
18
-
-
0023109845
-
Clonidine binds to imidazole binding sites as well as alpha 2-adrenoceptors in the ventrolateral medulla
-
Ernsberger, P., Meeley, M.P., Mann, J.J., Reis, D.J. (1987) Clonidine binds to imidazole binding sites as well as alpha 2-adrenoceptors in the ventrolateral medulla. Eur. J. Pharmacol., 134, 1-43.
-
(1987)
Eur. J. Pharmacol.
, vol.134
, pp. 1-43
-
-
Ernsberger, P.1
Meeley, M.P.2
Mann, J.J.3
Reis, D.J.4
-
19
-
-
0023851497
-
An endogenous substance with clonidine-like properties: Selective binding to imidazole sites in the ventrolateral medulla
-
Ernsberger, P., Meeley, M.P., Reis, D.J. (1988) An endogenous substance with clonidine-like properties: selective binding to imidazole sites in the ventrolateral medulla. Brain Res., 441, 309-318.
-
(1988)
Brain Res.
, vol.441
, pp. 309-318
-
-
Ernsberger, P.1
Meeley, M.P.2
Reis, D.J.3
-
20
-
-
0028983601
-
Alpha 2 adrenergic agonists prevent MK-801 neurotoxicity
-
Farber, N.B., Foster, J., Duhan, N.L., Olney, J.W. (1995) alpha 2 adrenergic agonists prevent MK-801 neurotoxicity. Neuropsychopharmacology, 12, 347-349.
-
(1995)
Neuropsychopharmacology
, vol.12
, pp. 347-349
-
-
Farber, N.B.1
Foster, J.2
Duhan, N.L.3
Olney, J.W.4
-
21
-
-
0017832401
-
Distribution and regulation of cyclic GMP in the central nervous system
-
Ferrendelli, J.A. (1978) Distribution and regulation of cyclic GMP in the central nervous system. Adv. Cyclic Nucleotide Protein Phosphorylation Res., 9, 453-464.
-
(1978)
Adv. Cyclic Nucleotide Protein Phosphorylation Res.
, vol.9
, pp. 453-464
-
-
Ferrendelli, J.A.1
-
22
-
-
0033230031
-
Measurement of responses from Gi-, Gs-, or Gq-coupled receptors by a multiple response element/cAMP response element-directed reporter assay
-
Fitzgerald, L.R., Mannan, I.J., Dytko, G.M., Wu, H.L., Nambi, P. (1999) Measurement of responses from Gi-, Gs-, or Gq-coupled receptors by a multiple response element/cAMP response element-directed reporter assay. Anal. Biochem., 275, 54-61.
-
(1999)
Anal. Biochem.
, vol.275
, pp. 54-61
-
-
Fitzgerald, L.R.1
Mannan, I.J.2
Dytko, G.M.3
Wu, H.L.4
Nambi, P.5
-
23
-
-
0028831462
-
Age-dependent increases of immunoreactive imidazoline receptors in the human brain: Possible association of a 29/30 kDa protein with the I2-imidazoline receptor identified by [3H]idazoxan
-
Garcia-Sevilla, J.A., Sastre, M., Escriba, P.V. (1995) Age-dependent increases of immunoreactive imidazoline receptors in the human brain: possible association of a 29/30 kDa protein with the I2-imidazoline receptor identified by [3H]idazoxan. Neurosci. Lett., 184, 133-136.
-
(1995)
Neurosci. Lett.
, vol.184
, pp. 133-136
-
-
Garcia-Sevilla, J.A.1
Sastre, M.2
Escriba, P.V.3
-
24
-
-
0023680850
-
Intraischemic extracellular release of dopamine and glutamate is associated with striatal vulnerability to ischemia
-
Globus, M.Y., Busto, R., Dietrich, W.D., Martinez, E., Ginsberg, M.D. (1988) Intraischemic extracellular release of dopamine and glutamate is associated with striatal vulnerability to ischemia. Neurosci. Lett., 91, 36-40.
-
(1988)
Neurosci. Lett.
, vol.91
, pp. 36-40
-
-
Globus, M.Y.1
Busto, R.2
Dietrich, W.D.3
Martinez, E.4
Ginsberg, M.D.5
-
25
-
-
0024377189
-
Direct evidence for acute and massive norepinephrine release in the hippocampus during transient iscjemia
-
Globus, M.Y., Busto, R., Dietrich, W.D., Martinez, E., Valdes, I., Ginsberg, M.D. (1989) Direct evidence for acute and massive norepinephrine release in the hippocampus during transient iscjemia. J. Cereb. Blood Flow Metab., 9, 892-896.
-
(1989)
J. Cereb. Blood Flow Metab.
, vol.9
, pp. 892-896
-
-
Globus, M.Y.1
Busto, R.2
Dietrich, W.D.3
Martinez, E.4
Valdes, I.5
Ginsberg, M.D.6
-
26
-
-
77956758378
-
Catecholamine receptors and signal transduction
-
Goldstein, D.S. (1998) Catecholamine receptors and signal transduction. Adv. Pharmacol., 42, 379-390.
-
(1998)
Adv. Pharmacol.
, vol.42
, pp. 379-390
-
-
Goldstein, D.S.1
-
27
-
-
0024592773
-
Postischemic administration of idazoxan, an alpha-2 adrenergic receptor antagonist, decreases neuronal damage in the rat brain
-
Gustafson, I., Miyauchi, Y., Wieloch, T.W. (1989) Postischemic administration of idazoxan, an alpha-2 adrenergic receptor antagonist, decreases neuronal damage in the rat brain. J. Cereb. Blood Flow Metab., 9, 171-174.
-
(1989)
J. Cereb. Blood Flow Metab.
, vol.9
, pp. 171-174
-
-
Gustafson, I.1
Miyauchi, Y.2
Wieloch, T.W.3
-
28
-
-
0025006009
-
Protection against ischemia-induced neuronal damage by the alpha 2-adrenoceptor antagonist idazoxan: Influence of time of administration and possible mechanisms of action
-
Gustafson, I., Westerberg, E., Wieloch, T. (1990) Protection against ischemia-induced neuronal damage by the alpha 2-adrenoceptor antagonist idazoxan: influence of time of administration and possible mechanisms of action. J. Cereb. Blood Flow Metab., 10, 885-894.
-
(1990)
J. Cereb. Blood Flow Metab.
, vol.10
, pp. 885-894
-
-
Gustafson, I.1
Westerberg, E.2
Wieloch, T.3
-
29
-
-
0028980282
-
Alpha sub 2-adrenoceptor agonist dexmetedomidine, protects against kainic acid-induced convulsions and neuronal damage
-
Halonen, T., Kotti, T,, Tuunanen, J., Toppinen, A., Miettinen, R., Riekkinen, P. (1995) Alpha sub 2-adrenoceptor agonist dexmetedomidine, protects against kainic acid-induced convulsions and neuronal damage. Brain Res., 693, 217-224.
-
(1995)
Brain Res.
, vol.693
, pp. 217-224
-
-
Halonen, T.1
Kotti, T.2
Tuunanen, J.3
Toppinen, A.4
Miettinen, R.5
Riekkinen, P.6
-
30
-
-
0027216695
-
Effects of halothane on EDRF/cGMP-mediated vascular smooth muscle relaxations
-
Hart, J.L., Jing, M., Bina, S., Freas, W., Van Dyke, R.A., Muldoon, S.M. (1993) Effects of halothane on EDRF/cGMP-mediated vascular smooth muscle relaxations. Anesthesiology, 79, 323-331.
-
(1993)
Anesthesiology
, vol.79
, pp. 323-331
-
-
Hart, J.L.1
Jing, M.2
Bina, S.3
Freas, W.4
Van Dyke, R.A.5
Muldoon, S.M.6
-
31
-
-
0029004852
-
Adrenergic receptor signal transduction and regulation
-
Hein, L., Kobilka, B.K. (1995) Adrenergic receptor signal transduction and regulation. Neuropharmacology, 34, 357-366.
-
(1995)
Neuropharmacology
, vol.34
, pp. 357-366
-
-
Hein, L.1
Kobilka, B.K.2
-
32
-
-
0025823374
-
Clonidine decrease plasma catecholamines and improves outcome from incomplete ischemia in the rat
-
Hoffman, W.E., Cheng, M.A., Thomas, C., Baughman, V.L., Albrecht, R.F. (1991) Clonidine decrease plasma catecholamines and improves outcome from incomplete ischemia in the rat. Anesth. Anaig., 73, 460-464.
-
(1991)
Anesth. Anaig.
, vol.73
, pp. 460-464
-
-
Hoffman, W.E.1
Cheng, M.A.2
Thomas, C.3
Baughman, V.L.4
Albrecht, R.F.5
-
34
-
-
0034046856
-
Dexmedetomidine-induced stimulation of glutamine oxidation in astrocytes: A possible mechanism for its neuroprotective activity
-
Huang, R., Chen, Y., Yu, A.C., Hertz, L. (2000) Dexmedetomidine-induced stimulation of glutamine oxidation in astrocytes: a possible mechanism for its neuroprotective activity. J. Cereb. Blood Flow Metab., 20, 895-898.
-
(2000)
J. Cereb. Blood Flow Metab.
, vol.20
, pp. 895-898
-
-
Huang, R.1
Chen, Y.2
Yu, A.C.3
Hertz, L.4
-
35
-
-
0032545715
-
Clonidine potentiates the neuropathic pain-relieving action of MK-801 while preventing its neurotoxic and hyperactivity side effects
-
Jevtovic-Todorovic, V., Wozniak, D.F., Powell, S., Nardi, A., Olney, J.W. (1998) Clonidine potentiates the neuropathic pain-relieving action of MK-801 while preventing its neurotoxic and hyperactivity side effects. Brain Res., 781, 202-211.
-
(1998)
Brain Res.
, vol.781
, pp. 202-211
-
-
Jevtovic-Todorovic, V.1
Wozniak, D.F.2
Powell, S.3
Nardi, A.4
Olney, J.W.5
-
36
-
-
0026778628
-
Nitric oxide synthase inhibitor dose-dependently and reversibly reduces the threshold for halothane anesthesia
-
Johns, R.A., Moscicki, J.C., DiFazio, C.A. (1992) Nitric oxide synthase inhibitor dose-dependently and reversibly reduces the threshold for halothane anesthesia. Anesthesiology, 77, 779-784.
-
(1992)
Anesthesiology
, vol.77
, pp. 779-784
-
-
Johns, R.A.1
Moscicki, J.C.2
DiFazio, C.A.3
-
37
-
-
0032588223
-
Neuroprotection by the alpha 2-adrenoceptor agonist, dexmedetomidine, in rat focal cerebral ischemia
-
Jolkkonen, J., Puurunen, K., Koistinaho, J., Kauppinen, R., Haapalinna, A., Nieminen, L., Sivenius, J. (1999) Neuroprotection by the alpha 2-adrenoceptor agonist, dexmedetomidine, in rat focal cerebral ischemia. Eur. J. Pharmacol., 372, 31-36.
-
(1999)
Eur. J. Pharmacol.
, vol.372
, pp. 31-36
-
-
Jolkkonen, J.1
Puurunen, K.2
Koistinaho, J.3
Kauppinen, R.4
Haapalinna, A.5
Nieminen, L.6
Sivenius, J.7
-
39
-
-
0025196237
-
Binding of [3H]p-aminoclonidine to two sites, alpha 2-adrenoceptors and imidazoline binding sites: Distribution of imidazoline binding sites in rat brain
-
Kamisaki, Y., Ishikawa, T., Takao, Y., Omodani, H., Kuno, N., Itoh, T. (1990) Binding of [3H]p-aminoclonidine to two sites, alpha 2-adrenoceptors and imidazoline binding sites: distribution of imidazoline binding sites in rat brain. Brain Res., 514, 15-21.
-
(1990)
Brain Res.
, vol.514
, pp. 15-21
-
-
Kamisaki, Y.1
Ishikawa, T.2
Takao, Y.3
Omodani, H.4
Kuno, N.5
Itoh, T.6
-
40
-
-
0036310780
-
Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent
-
Kapinya, K.J., Lowl, D., Futterer, C., Maurer, M., Waschke, K.F., Isaev, N.K., Dirnagl, U. (2002) Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent. Stroke, 33, 1889-1898.
-
(2002)
Stroke
, vol.33
, pp. 1889-1898
-
-
Kapinya, K.J.1
Lowl, D.2
Futterer, C.3
Maurer, M.4
Waschke, K.F.5
Isaev, N.K.6
Dirnagl, U.7
-
41
-
-
0012113312
-
Dexmedetomidine does not attenuate increases in excitatory amino acids after transient global ischemia in the rabbit
-
Kim, H.K., Zornow, M.H,, Strnat, M.A., Maze, M. (1996) Dexmedetomidine does not attenuate increases in excitatory amino acids after transient global ischemia in the rabbit. J. Neurosurg. Anesthesiol., 8, 230-236.
-
(1996)
J. Neurosurg. Anesthesiol.
, vol.8
, pp. 230-236
-
-
Kim, H.K.1
Zornow, M.H.2
Strnat, M.A.3
Maze, M.4
-
42
-
-
0034012430
-
Cell volume in the CNS: Regulation and implications for nervous system function and pathology
-
Kimelberg, H.K. (2000) Cell volume in the CNS: regulation and implications for nervous system function and pathology. Neuroscientist, 6, 13-24.
-
(2000)
Neuroscientist
, vol.6
, pp. 13-24
-
-
Kimelberg, H.K.1
-
43
-
-
20344374445
-
Astrocytic swelling in cerebral ischemia as a possible cause of injury and target for therapy
-
Kimelberg, H.K. (2005) Astrocytic swelling in cerebral ischemia as a possible cause of injury and target for therapy. Glia, 50, 389-397.
-
(2005)
Glia
, vol.50
, pp. 389-397
-
-
Kimelberg, H.K.1
-
44
-
-
0026629481
-
Effect of Tizanidine morphine physical dependence: Attenuation and intensification
-
Koyuncuoǧlu, H., Aricioǧlu, F., Üresin, Y., Dizdar, Y., Esin, Y. (1992) Effect of Tizanidine morphine physical dependence: attenuation and intensification. Pharmacol. Biochem. Behav., 42, 693-698.
-
(1992)
Pharmacol. Biochem. Behav.
, vol.42
, pp. 693-698
-
-
Koyuncuoǧlu, H.1
Aricioǧlu, F.2
Üresin, Y.3
Dizdar, Y.4
Esin, Y.5
-
45
-
-
0030768341
-
Neuroprotective effects of dexmedetomidine in the gerbil hippocampus after transient global ischemia
-
Kuhmonen, J., Pokorny, J., Miettinen, R., Haapalinna, A., Jolkkonen, J., Riekkinen, P., Sivenius, J. (1997) Neuroprotective effects of dexmedetomidine in the gerbil hippocampus after transient global ischemia. Anesthesiology, 87, 371-377.
-
(1997)
Anesthesiology
, vol.87
, pp. 371-377
-
-
Kuhmonen, J.1
Pokorny, J.2
Miettinen, R.3
Haapalinna, A.4
Jolkkonen, J.5
Riekkinen, P.6
Sivenius, J.7
-
46
-
-
0029895790
-
Genetic evidence for involvement of multiple effector systems in alpha 2A-adrenergic receptor inhibition of stimulus-secretion coupling
-
Lakhlani, P.P., Lovinger, D.M., Limbird, L.E. (1996) Genetic evidence for involvement of multiple effector systems in alpha 2A-adrenergic receptor inhibition of stimulus-secretion coupling. Mol. Pharmacol., 50, 96-103.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 96-103
-
-
Lakhlani, P.P.1
Lovinger, D.M.2
Limbird, L.E.3
-
47
-
-
0032799421
-
Inhibition of central monoamine oxidase by imidazoline2 site-selective ligands
-
Lalies, M.D., Hibell, A., Hudson, A.L., Nutt, D.J. (1999) Inhibition of central monoamine oxidase by imidazoline2 site-selective ligands. Ann. NY Acad. Sci., 881, 114-117.
-
(1999)
Ann. NY Acad. Sci.
, vol.881
, pp. 114-117
-
-
Lalies, M.D.1
Hibell, A.2
Hudson, A.L.3
Nutt, D.J.4
-
48
-
-
0019116111
-
Presynaptic regulation of the release of catecholamines
-
Langer, S.Z. (1980) Presynaptic regulation of the release of catecholamines. Pharmacol. Rev., 32, 337-362.
-
(1980)
Pharmacol. Rev.
, vol.32
, pp. 337-362
-
-
Langer, S.Z.1
-
49
-
-
0036137630
-
Effects of α2-adrenoceptor agonists on perinatal excitotoxic brain injury: Comparison of clonidine and dexmedetomidine
-
Laudenbach, V., Mantz, J., Lagercrantz, H., Demonts, J., Evrard, P., Gressens, P. (2002) Effects of α2-adrenoceptor agonists on perinatal excitotoxic brain injury: comparison of clonidine and dexmedetomidine, Anesthesiology, 96, 134-141.
-
(2002)
Anesthesiology
, vol.96
, pp. 134-141
-
-
Laudenbach, V.1
Mantz, J.2
Lagercrantz, H.3
Demonts, J.4
Evrard, P.5
Gressens, P.6
-
50
-
-
0024215586
-
Behavioral and neurochemical effects of metedomidine, a novel veterinary sedative
-
MacDonald, E., Scheinin, H., Scheinin, M. (1988) Behavioral and neurochemical effects of metedomidine, a novel veterinary sedative. Eur. J. Pharmacol., 158, 119-127.
-
(1988)
Eur. J. Pharmacol.
, vol.158
, pp. 119-127
-
-
MacDonald, E.1
Scheinin, H.2
Scheinin, M.3
-
51
-
-
0022579370
-
Influence of clonidine and a new related imidazoline derivative (Tizanidine) on rat gastric mucosa
-
Maeda-Hagiwara, M., Watanabe, H., Kanaoka, R., Watanabe, K. (1986) Influence of clonidine and a new related imidazoline derivative (Tizanidine) on rat gastric mucosa. Pharmacology, 32, 109-113.
-
(1986)
Pharmacology
, vol.32
, pp. 109-113
-
-
Maeda-Hagiwara, M.1
Watanabe, H.2
Kanaoka, R.3
Watanabe, K.4
-
52
-
-
0027248053
-
Neuroprotection by the (alpha sub 2-adrenoceptor agonist dexmetedomidine in a focal model of cerebral ischemia
-
Maier, C., Steinberg, G.K., Sun, G.H., Zhi, G.T., Maze, M. (1993) Neuroprotection by the (alpha sub 2-adrenoceptor agonist dexmetedomidine in a focal model of cerebral ischemia. Anesthesiology, 79, 306-312.
-
(1993)
Anesthesiology
, vol.79
, pp. 306-312
-
-
Maier, C.1
Steinberg, G.K.2
Sun, G.H.3
Zhi, G.T.4
Maze, M.5
-
53
-
-
0026586243
-
Reduction in focal cerebral ischemia by agents acting at imidazole receptors
-
Maiese, K., Pek, L., Berger, S.B., Reis, D.J. (1992) Reduction in focal cerebral ischemia by agents acting at imidazole receptors. J. Cereb. Blood Flow Metab., 12, 53-63.
-
(1992)
J. Cereb. Blood Flow Metab.
, vol.12
, pp. 53-63
-
-
Maiese, K.1
Pek, L.2
Berger, S.B.3
Reis, D.J.4
-
54
-
-
0025903494
-
Alpha-2 adrenoceptor agonists: Defining the role in clinical anesthesia
-
Maze, M., Tranquilli, W. (1991) Alpha-2 adrenoceptor agonists: Defining the role in clinical anesthesia. Anesthesiology, 74, 581-605.
-
(1991)
Anesthesiology
, vol.74
, pp. 581-605
-
-
Maze, M.1
Tranquilli, W.2
-
55
-
-
0016290257
-
Disordered neurotransmitter function
-
Meyer, J.S., Welch, K.M., Okamoto, S., Shimazu, K. (1974) Disordered neurotransmitter function. Brain, 97, 655-664.
-
(1974)
Brain
, vol.97
, pp. 655-664
-
-
Meyer, J.S.1
Welch, K.M.2
Okamoto, S.3
Shimazu, K.4
-
56
-
-
0024440439
-
Are there multiple imidazoline binding sites?
-
Michel, M.C., Insel, P.A. (1989) Are there multiple imidazoline binding sites? Trends Pharmacol. Sci., 10, 342-344.
-
(1989)
Trends Pharmacol. Sci.
, vol.10
, pp. 342-344
-
-
Michel, M.C.1
Insel, P.A.2
-
57
-
-
0025192648
-
Nonadrenergic [3H]idazoxan binding sites are physically distinct from alpha 2-adrenergic receptors
-
Michel, M.C., Regan, J.W., Gerhardt, M.A., Neubig, R.R., Insel, P.A., Motulsky, H.J. (1990) Nonadrenergic [3H]idazoxan binding sites are physically distinct from alpha 2-adrenergic receptors. Mol. Pharmacol., 37, 65-68.
-
(1990)
Mol. Pharmacol.
, vol.37
, pp. 65-68
-
-
Michel, M.C.1
Regan, J.W.2
Gerhardt, M.A.3
Neubig, R.R.4
Insel, P.A.5
Motulsky, H.J.6
-
58
-
-
9344227578
-
Astrocytic swelling in neuropathology
-
Kettenmann, H.O. and Ransom, B.R. Eds, New York, Oxford University Press
-
Mongin, A.A., Kimelberg, H.K. (2005) Astrocytic swelling in neuropathology. In: Kettenmann, H.O. and Ransom, B.R. Eds, Neuroglia. New York, Oxford University Press. pp. 550-562.
-
(2005)
Neuroglia
, pp. 550-562
-
-
Mongin, A.A.1
Kimelberg, H.K.2
-
59
-
-
0026029965
-
Subtypes of adrenergic receptors and intracellular mechanisms involved in modulatory effects of noradrenaline on glutamate
-
Mori-Okamoto, J., Namii, Y., Tatsuno, J. (1991) Subtypes of adrenergic receptors and intracellular mechanisms involved in modulatory effects of noradrenaline on glutamate. Brain Res., 539, 67-75.
-
(1991)
Brain Res.
, vol.539
, pp. 67-75
-
-
Mori-Okamoto, J.1
Namii, Y.2
Tatsuno, J.3
-
60
-
-
0028897733
-
Clinical experience with excitatory amino acid antagonist drugs
-
Muir, K.W., Lees, K.R. (1995) Clinical experience with excitatory amino acid antagonist drugs. Stroke, 26, 503-513.
-
(1995)
Stroke
, vol.26
, pp. 503-513
-
-
Muir, K.W.1
Lees, K.R.2
-
62
-
-
0027377404
-
Nitric oxide and anesthesia
-
Nakamura, K., Mori, K. (1993) Nitric oxide and anesthesia. Anesth. Analg., 77, 877-879.
-
(1993)
Anesth. Analg.
, vol.77
, pp. 877-879
-
-
Nakamura, K.1
Mori, K.2
-
63
-
-
0025823740
-
Effect of recirculation on exacerbation of ischemic vascular lesions in rat brain
-
Nishigaya, K., Yoshida, Y., Sasuga, M., Nukui, H., Ooneda, G. (1991) effect of recirculation on exacerbation of ischemic vascular lesions in rat brain. Stroke, 22, 165-204.
-
(1991)
Stroke
, vol.22
, pp. 165-204
-
-
Nishigaya, K.1
Yoshida, Y.2
Sasuga, M.3
Nukui, H.4
Ooneda, G.5
-
64
-
-
0035805092
-
Control of glutamate clearance and synaptic efficacy by glial coverage of neurons
-
Oliet, S.H., Piet, R., Poulain, D.A. (2001) Control of glutamate clearance and synaptic efficacy by glial coverage of neurons. Science, 292, 923-926.
-
(2001)
Science
, vol.292
, pp. 923-926
-
-
Oliet, S.H.1
Piet, R.2
Poulain, D.A.3
-
65
-
-
0031658641
-
Rilmenidine elevates cytosolic free calcium concentration in suspended cerebral astrocytes
-
Ozog, M.A., Wilson, J.X., Dixon, S.J., Cechetto, D.F. (1998) Rilmenidine elevates cytosolic free calcium concentration in suspended cerebral astrocytes. J. Neurochem., 71, 1429-1435.
-
(1998)
J. Neurochem.
, vol.71
, pp. 1429-1435
-
-
Ozog, M.A.1
Wilson, J.X.2
Dixon, S.J.3
Cechetto, D.F.4
-
66
-
-
0030026927
-
The elusive family of imidazoline binding sites
-
Parini, A., Moudanos, C.G., Pizzinat, N., Lanier, S.M. (1996) The elusive family of imidazoline binding sites. Trends Pharmacol. Sci., 17, 13-16.
-
(1996)
Trends Pharmacol. Sci.
, vol.17
, pp. 13-16
-
-
Parini, A.1
Moudanos, C.G.2
Pizzinat, N.3
Lanier, S.M.4
-
67
-
-
0028566557
-
Protection of focal ischemic infarction by rilmenidine in the animal: Evidence that interactions with central imidazoline receptors may be neuroprotective
-
Reis, D.J., Regunathan, S., Golanov, E.V., Feinstein, D.L. (1994) Protection of focal ischemic infarction by rilmenidine in the animal: evidence that interactions with central imidazoline receptors may be neuroprotective. Am. J. Cardiol., 74, 25A-30A.
-
(1994)
Am. J. Cardiol.
, vol.74
-
-
Reis, D.J.1
Regunathan, S.2
Golanov, E.V.3
Feinstein, D.L.4
-
68
-
-
0026680524
-
Imidazoline receptors in the nervous system
-
Reis, D.J., Regunathan, S., Wang, H., Feinstein, D.L., Meeley, M.P. (1992) Imidazoline receptors in the nervous system. Fundam. Clin. Pharmacol., 6, 23S-29S.
-
(1992)
Fundam. Clin. Pharmacol.
, vol.6
-
-
Reis, D.J.1
Regunathan, S.2
Wang, H.3
Feinstein, D.L.4
Meeley, M.P.5
-
69
-
-
0027140282
-
Presynaptic inhibition of excitatory transmission mediated by alpha adrenergic receptors in area Ca3 of the rat hippocampus in vitro
-
Scanziani, M., Gahwwiler, B.H., Thompson, S.M. (1993) Presynaptic inhibition of excitatory transmission mediated by alpha adrenergic receptors in area Ca3 of the rat hippocampus in vitro. J Neurosci., 13, 5393-5401.
-
(1993)
J. Neurosci.
, vol.13
, pp. 5393-5401
-
-
Scanziani, M.1
Gahwwiler, B.H.2
Thompson, S.M.3
-
70
-
-
0023774654
-
Mechanisms of ischemic brain damage
-
Siesjö, B.K. (1988) Mechanisms of ischemic brain damage. Crit. Care Med., 16, 954-963.
-
(1988)
Crit. Care Med.
, vol.16
, pp. 954-963
-
-
Siesjö, B.K.1
-
71
-
-
0024556434
-
Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: A unifying hypothesis
-
Siesjo, B.K., Bengtsson, F. (1989) Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis. J. Cereb. Blood Flow Metab., 9, 127-140.
-
(1989)
J. Cereb. Blood Flow Metab.
, vol.9
, pp. 127-140
-
-
Siesjo, B.K.1
Bengtsson, F.2
-
72
-
-
0036107388
-
Ion regulation in the brain: Implications for pathophysiology
-
Somjen, G.G. (2002) Ion regulation in the brain: implications for pathophysiology. Neuroscientist, 8, 254-267.
-
(2002)
Neuroscientist
, vol.8
, pp. 254-267
-
-
Somjen, G.G.1
-
74
-
-
0027393383
-
Adrenoceptors and their second messenger systems
-
Summers, R.J., McMartin, L.R. (1993) Adrenoceptors and their second messenger systems. J. Neurochem., 60, 10-23.
-
(1993)
J. Neurochem.
, vol.60
, pp. 10-23
-
-
Summers, R.J.1
McMartin, L.R.2
-
75
-
-
0026706979
-
A point mutation of alpha 2 -adrenoceptor that blocks coupling to potassium but not calcium currents
-
Surprenant, A., Horstman, D.A., Akbarali, H., Limbird, L.E. (1992) A point mutation of alpha 2 -adrenoceptor that blocks coupling to potassium but not calcium currents. Science, 257, 977-980.
-
(1992)
Science
, vol.257
, pp. 977-980
-
-
Surprenant, A.1
Horstman, D.A.2
Akbarali, H.3
Limbird, L.E.4
-
76
-
-
0036128399
-
Imidazoline antihypertensive drugs: A critical review on their mechanism of action
-
Szabo, B. (2002) Imidazoline antihypertensive drugs: a critical review on their mechanism of action. Pharmacol. Therap., 93, 1-35.
-
(2002)
Pharmacol. Therap.
, vol.93
, pp. 1-35
-
-
Szabo, B.1
-
77
-
-
0029773856
-
Effects of dexmetedomide on hypoxia-evoked glutamate release and glutamate receptor activity in hippocampal slices
-
Talke, P., Bickler, P.E. (1996) Effects of dexmetedomide on hypoxia-evoked glutamate release and glutamate receptor activity in hippocampal slices. Anesthesiology, 85, 551-557.
-
(1996)
Anesthesiology
, vol.85
, pp. 551-557
-
-
Talke, P.1
Bickler, P.E.2
-
78
-
-
0029784446
-
2 - Adrenoceptor agonists decrease cyclic guanosine 3′,5′-monophosphate in the mouse brain
-
2 - adrenoceptor agonists decrease cyclic guanosine 3′,5′-monophosphate in the mouse brain. Anesthesiology, 85, 544-550.
-
(1996)
Anesthesiology
, vol.85
, pp. 544-550
-
-
Vulliemoz, Y.1
Shen, H.2
-
79
-
-
0023867041
-
Monoamine neurotransmitters in the evolution of infarction in ischemic striatum: Morphologic correlation
-
Weinberger, R., Nieves-Rosa, J. (1988) Monoamine neurotransmitters in the evolution of infarction in ischemic striatum: morphologic correlation. J. Neural Trans., 71, 133-142.
-
(1988)
J. Neural Trans.
, vol.71
, pp. 133-142
-
-
Weinberger, R.1
Nieves-Rosa, J.2
-
80
-
-
0025281106
-
Further characterization of the guinea pig cerebral cortex idazoxan receptor: Solubilization, distinction from the imidazole site, and demonstration of cirazoline as an idazoxan receptor-selective drug
-
Wikberg, J.E., Uhlen, S. (1990) Further characterization of the guinea pig cerebral cortex idazoxan receptor: solubilization, distinction from the imidazole site, and demonstration of cirazoline as an idazoxan receptor-selective drug. J. Neurochem., 55, 192-203.
-
(1990)
J. Neurochem.
, vol.55
, pp. 192-203
-
-
Wikberg, J.E.1
Uhlen, S.2
-
81
-
-
1942521054
-
Clonidine preconditioning decreases brain infarct sizes and improves neurological outcome from transient forebrain ischemia in the rat
-
Zhang, Y. (2004) Clonidine preconditioning decreases brain infarct sizes and improves neurological outcome from transient forebrain ischemia in the rat. Neuroscience, 125, 625-631.
-
(2004)
Neuroscience
, vol.125
, pp. 625-631
-
-
Zhang, Y.1
|