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Volumn 31, Issue 10, 2011, Pages

α2-Adrenoceptors do not mediate neuroprotection in acute ischemic stroke in mice

Author keywords

2 adrenoceptors; blood pressure; clonidine; experimental stroke; hemodynamics; neuroprotection

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2A ADRENERGIC RECEPTOR; ALPHA 2B ADRENERGIC RECEPTOR; ALPHA 2C ADRENERGIC RECEPTOR; CLONIDINE;

EID: 80053564028     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2011.110     Document Type: Article
Times cited : (17)

References (34)
  • 1
    • 0022870943 scopus 로고
    • Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats
    • Bederson JB, Pitts LH, Germano SM, Nishimura MC, Davis RL, Bartkowski HM (1986a) Evaluation of 2,3, 5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke 17:1304-8 (Pubitemid 17008976)
    • (1986) Stroke , vol.17 , Issue.6 , pp. 1304-1308
    • Bederson, J.B.1    Pitts, L.H.2    Germano, S.M.3
  • 2
    • 0022483434 scopus 로고
    • Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination
    • Bederson JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL, Bartkowski H (1986b) Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 17:472-6 (Pubitemid 16085691)
    • (1986) Stroke , vol.17 , Issue.3 , pp. 472-476
    • Bederson, J.B.1    Pitts, L.H.2    Tsuji, M.3
  • 3
    • 0036200610 scopus 로고    scopus 로고
    • Fine tuning of sympathetic transmitter release via ionotropic and metabotropic presynaptic receptors
    • DOI 10.1124/pr.54.1.43
    • Boehm S, Kubista H (2002) Fine tuning of sympathetic transmitter release via ionotropic and metabotropic presynaptic receptors. Pharmacol Rev 54:43-99 (Pubitemid 34208829)
    • (2002) Pharmacological Reviews , vol.54 , Issue.1 , pp. 43-99
    • Boehm, S.1    Kubista, H.2
  • 4
    • 77953200044 scopus 로고    scopus 로고
    • Interleukin-18 does not influence infarct volume or functional outcome in the early stage after transient focal brain ischemia in mice
    • Braeuninger S, Kleinschnitz C, Stoll G (2010) Interleukin-18 does not influence infarct volume or functional outcome in the early stage after transient focal brain ischemia in mice. Exp Transl Stroke Med 2:1
    • (2010) Exp Transl Stroke Med , vol.2 , pp. 1
    • Braeuninger, S.1    Kleinschnitz, C.2    Stoll, G.3
  • 5
    • 0037027480 scopus 로고    scopus 로고
    • 2-adrenoceptor subtypes prevents progression of heart failure
    • DOI 10.1161/01.CIR.0000036600.39600.66
    • Brede M, Wiesmann F, Jahns R, Hadamek K, Arnolt C, Neubauer S, Lohse MJ, Hein L (2002) Feedback inhibition of catecholamine release by two different a2-adrenoceptor subtypes prevents progression of heart failure. Circulation 106:2491-6 (Pubitemid 35278807)
    • (2002) Circulation , vol.106 , Issue.19 , pp. 2491-2496
    • Brede, M.1    Wiesmann, F.2    Jahns, R.3    Hadamek, K.4    Arnolt, C.5    Neubauer, S.6    Lohse, M.J.7    Hein, L.8
  • 7
    • 0031439697 scopus 로고    scopus 로고
    • Monofilament intraluminal middle cerebral artery occlusion in the mouse
    • Clark WM, Lessov NS, Dixon MP, Eckenstein F (1997) Monofilament intraluminal middle cerebral artery occlusion in the mouse. Neurol Res 19:641-8 (Pubitemid 28006649)
    • (1997) Neurological Research , vol.19 , Issue.6 , pp. 641-648
    • Clark, W.M.1    Lessov, N.S.2    Dixon, M.P.3    Eckenstein, F.4
  • 8
    • 0030060152 scopus 로고    scopus 로고
    • Procedural and strain-related variables significantly affect outcome in a murine model of focal cerebral ischemia
    • discussion 32
    • Connolly Jr ES, Winfree CJ, Stern DM, Solomon RA, Pinsky DJ (1996) Procedural and strain-related variables significantly affect outcome in a murine model of focal cerebral ischemia. Neurosurgery 38:523-31;, discussion 32
    • (1996) Neurosurgery , vol.38 , pp. 523-531
    • Connolly Jr., E.S.1    Winfree, C.J.2    Stern, D.M.3    Solomon, R.A.4    Pinsky, D.J.5
  • 9
    • 0034741828 scopus 로고    scopus 로고
    • High level of α2-adrenoceptor in rat foetal liver and placenta is due to α2B-subtype expression in haematopoietic cells of the erythrocyte lineage
    • Cussac D, Schaak S, Denis C, Flordellis C, Calise D, Paris H (2001) High level of alpha2-adrenoceptor in rat foetal liver and placenta is due to alpha2B-subtype expression in haematopoietic cells of the erythrocyte lineage. Br J Pharmacol 133:1387-95 (Pubitemid 32783501)
    • (2001) British Journal of Pharmacology , vol.133 , Issue.8 , pp. 1387-1395
    • Cussac, D.1    Schaak, S.2    Denis, C.3    Flordellis, C.4    Calise, D.5    Paris, H.6
  • 10
    • 33751327483 scopus 로고    scopus 로고
    • Bench to bedside: The quest for quality in experimental stroke research
    • DOI 10.1038/sj.jcbfm.9600298, PII 9600298
    • Dirnagl U (2006) Bench to bedside: the quest for quality in experimental stroke research. J Cereb Blood Flow Metab 26:1465-78 (Pubitemid 44809076)
    • (2006) Journal of Cerebral Blood Flow and Metabolism , vol.26 , Issue.12 , pp. 1465-1478
    • Dirnagl, U.1
  • 11
    • 39349100845 scopus 로고    scopus 로고
    • Presynaptic metabotropic receptors for acetylcholine and adrenaline/noradrena-line
    • Gilsbach R, Hein L (2008) Presynaptic metabotropic receptors for acetylcholine and adrenaline/noradrena-line. Handb Exp Pharmacol 184:261-88
    • (2008) Handb Exp Pharmacol , vol.184 , pp. 261-88
    • Gilsbach, R.1    Hein, L.2
  • 14
    • 0023680850 scopus 로고
    • Intra-ischemic extracellular release of dopamine and glutamate is associated with striatal vulnerability to ischemia
    • Globus MY, Busto R, Dietrich WD, Martinez E, Valdes I, Ginsberg MD (1988) Intra-ischemic extracellular release of dopamine and glutamate is associated with striatal vulnerability to ischemia. Neurosci Lett 91:36-40
    • (1988) Neurosci Lett , vol.91 , pp. 36-40
    • Globus, M.Y.1    Busto, R.2    Dietrich, W.D.3    Martinez, E.4    Valdes, I.5    Ginsberg, M.D.6
  • 15
    • 0028980282 scopus 로고
    • Alpha 2-adrenoceptor agonist, dexmedetomidine, protects against kainic acid-induced convulsions and neuronal damage
    • Halonen T, Kotti T, Tuunanen J, Toppinen A, Miettinen R, Riekkinen PJ (1995) Alpha 2-adrenoceptor agonist, dexmedetomidine, protects against kainic acid-induced convulsions and neuronal damage. Brain Res 693: 217-24
    • (1995) Brain Res , vol.693 , pp. 217-24
    • Halonen, T.1    Kotti, T.2    Tuunanen, J.3    Toppinen, A.4    Miettinen, R.5    Riekkinen, P.J.6
  • 16
    • 0025823374 scopus 로고
    • Clonidine decreases plasma cate-cholamines and improves outcome from incomplete ischemia in the rat
    • Hoffman WE, Cheng MA, Thomas C, Baughman VL, Albrecht RF (1991a) Clonidine decreases plasma cate-cholamines and improves outcome from incomplete ischemia in the rat. Anesth Analg 73:460-4
    • (1991) Anesth Analg , vol.73 , pp. 460-4
    • Hoffman, W.E.1    Cheng, M.A.2    Thomas, C.3    Baughman, V.L.4    Albrecht, R.F.5
  • 18
    • 33748053679 scopus 로고    scopus 로고
    • Molecular mechanisms underlying the modulation of exocytotic noradrenaline release via presynaptic receptors
    • DOI 10.1016/j.pharmthera.2006.04.005, PII S0163725806000623
    • Kubista H, Boehm S (2006) Molecular mechanisms underlying the modulation of exocytotic noradrenaline release via presynaptic receptors. Pharmacol Ther 112: 213-42 (Pubitemid 44301493)
    • (2006) Pharmacology and Therapeutics , vol.112 , Issue.1 , pp. 213-242
    • Kubista, H.1    Boehm, S.2
  • 19
    • 0034896255 scopus 로고    scopus 로고
    • Effects of dexmedetomidine after transient and permanent occlusion of the middle cerebral artery in the rat
    • DOI 10.1007/s007020170071
    • Kuhmonen J, Haapalinna A, Sivenius J (2001) Effects of dexmedetomidine after transient and permanent occlusion of the middle cerebral artery in the rat. J Neural Transm 108:261-71 (Pubitemid 32703899)
    • (2001) Journal of Neural Transmission , vol.108 , Issue.3 , pp. 261-271
    • Kuhmonen, J.1    Haapalinna, A.2    Sivenius, J.3
  • 21
    • 0027248053 scopus 로고
    • 2-adrenoreceptor agonist dexmedetomidine in a focal model of cerebral ischemia
    • Maier C, Steinberg GK, Sun GH, Zhi GT, Maze M (1993) Neuroprotection by the alpha 2-adrenoreceptor agonist dexmedetomidine in a focal model of cerebral ischemia. Anesthesiology 79:306-12 (Pubitemid 23224843)
    • (1993) Anesthesiology , vol.79 , Issue.2 , pp. 306-312
    • Maier, C.1    Steinberg, G.K.2    Guo Hua Sun3    Guo Tian Zhi4    Maze, M.5
  • 22
    • 0017578293 scopus 로고
    • Variations in mean cerebral blood flow under anesthesia at rest and during cortical activation
    • Palmer NI, Thomas DJ, MacGillivray BB, Du Boulay GH, Marshall J, Russell RR, Symon L (1977) Variations in mean cerebral blood flow under anesthesia at rest and during cortical activation. Stroke 8:269-71 (Pubitemid 8078371)
    • (1977) Stroke , vol.8 , Issue.2 , pp. 269-271
    • Palmer, N.I.1    Thomas, D.J.2    MacGillivray, B.B.3
  • 23
    • 31444449957 scopus 로고    scopus 로고
    • 2A-adrenoceptor subtype
    • DOI 10.1213/01.ane.0000194301.79118.e9
    • Paris A, Mantz J, Tonner PH, Hein L, Brede M, Gressens P (2006) The effects of dexmedetomidine on perinatal excitotoxic brain injury are mediated by the alpha2A-adrenoceptor subtype. Anesth Analg 102:456-61 (Pubitemid 43152595)
    • (2006) Anesthesia and Analgesia , vol.102 , Issue.2 , pp. 456-461
    • Paris, A.1    Mantz, J.2    Tonner, P.H.3    Hein, L.4    Brede, M.5    Gressens, P.6
  • 25
    • 0036636053 scopus 로고    scopus 로고
    • Placental alpha(2)-adrenoceptors control vascular development at the interface between mother and embryo
    • Philipp M, Brede ME, Hadamek K, Gessler M, Lohse MJ, Hein L (2002b) Placental alpha(2)-adrenoceptors control vascular development at the interface between mother and embryo. Nat Genet 31:311-5
    • (2002) Nat Genet , vol.31 , pp. 311-5
    • Philipp, M.1    Brede, M.E.2    Hadamek, K.3    Gessler, M.4    Lohse, M.J.5    Hein, L.6
  • 26
    • 0346687568 scopus 로고    scopus 로고
    • Adrenergic receptor knockout mice: Distinct functions of 9 receptor subtypes
    • DOI 10.1016/j.pharmthera.2003.10.004
    • Philipp M, Hein L (2004) Adrenergic receptor knockout mice: distinct functions of 9 receptor subtypes. Pharmacol Ther 101:65-74 (Pubitemid 38068526)
    • (2004) Pharmacology and Therapeutics , vol.101 , Issue.1 , pp. 65-74
    • Philipp, M.1    Hein, L.2
  • 29
    • 44449083976 scopus 로고    scopus 로고
    • Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia
    • Shin HK, Nishimura M, Jones PB, Ay H, Boas DA, Moskowitz MA, Ayata C (2008) Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia. Stroke 39:1548-55
    • (2008) Stroke , vol.39 , pp. 1548-55
    • Shin, H.K.1    Nishimura, M.2    Jones, P.B.3    Ay, H.4    Boas, D.A.5    Moskowitz, M.A.6    Ayata, C.7
  • 30
    • 0020041444 scopus 로고
    • Cortical injury without ischemia produced by topical monoamines
    • Stein SC, Cracco RQ (1982) Cortical injury without ischemia produced by topical monoamines. Stroke 13:74-83 (Pubitemid 12219052)
    • (1982) Stroke , vol.13 , Issue.1 , pp. 74-83
    • Stein, S.C.1    Cracco, R.Q.2
  • 31
    • 15844362714 scopus 로고    scopus 로고
    • G protein βγ subunits mediate presynaptic inhibition of transmitter release from rat superior cervical ganglion neurones in culture
    • DOI 10.1113/jphysiol.2004.080192
    • Stephens GJ, Mochida S (2005) G protein {beta}{gamma} subunits mediate presynaptic inhibition of transmitter release from rat superior cervical ganglion neurones in culture. J Physiol 563:765-76 (Pubitemid 40425593)
    • (2005) Journal of Physiology , vol.563 , Issue.3 , pp. 765-776
    • Stephens, G.J.1    Mochida, S.2
  • 33
    • 1942521054 scopus 로고    scopus 로고
    • Clonidine preconditioning decreases infarct size and improves neurological outcome from transient forebrain ischemia in the rat
    • DOI 10.1016/j.neuroscience.2004.02.011, PII S0306452204001277
    • Zhang Y (2004) Clonidine preconditioning decreases infarct size and improves neurological outcome from transient forebrain ischemia in the rat. Neuroscience 125:625-31 (Pubitemid 38510172)
    • (2004) Neuroscience , vol.125 , Issue.3 , pp. 625-631
    • Zhang, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.