pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion

Journal of Experimental Medicine

Volumn 213, Issue 12, 2016, Pages 2811-2829

  Ozga, Aleksandra J ^a   Moalli, Federica ^a   Abe, Jun ^a   Swoger, Jim ^b,c   Sharpe, James ^b,c,d   Zehn, Dietmar ^e   Kreutzfeldt, Mario ^f   Merkler, Doron ^f   Ripoll, Jorge ^g,h   Stein, Jens V ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^c UNIVERSITAT POMPEU FABRA   (Spain)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^e LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^f UNIVERSITY OF GENEVA   (Switzerland)

^g UNIVERSIDAD CARLOS III DE MADRID   (Spain)

^h HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CHEMOKINE RECEPTOR CXCR3; INTERFERON REGULATORY FACTOR 4; CD69 ANTIGEN; GRANZYME; LECTIN; LEUKOCYTE ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PEPTIDE; T LYMPHOCYTE ANTIGEN;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ARTICLE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL EXPANSION; CELL INTERACTION; CELL MATURATION; CELL MIGRATION; COMPARATIVE STUDY; CONTROLLED STUDY; DAUGHTER CELL; DENDRITIC CELL; FLOW CYTOMETRY; FLUORESCENCE; FOLLICULAR DENDRITIC CELL; GENE EXPRESSION; LYMPH VESSEL; LYMPHOID TISSUE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; ANIMAL; C57BL MOUSE; CELL COMMUNICATION; CELL PROLIFERATION; CROSS PRESENTATION; CYTOLOGY; CYTOTOXICITY; GENE EXPRESSION REGULATION; IMAGE PROCESSING; IMMUNOLOGY; LYMPH NODE; METABOLISM; SIGNAL TRANSDUCTION; VIRUS INFECTION;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CD8-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CROSS-PRIMING; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; GENE EXPRESSION REGULATION; GRANZYMES; IMAGE PROCESSING, COMPUTER-ASSISTED; LECTINS, C-TYPE; LYMPH NODES; LYMPHATIC VESSELS; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE, INBRED C57BL; PEPTIDES; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; VIRUS DISEASES;

EID: 84999672364     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20160206     Document Type: Article

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