T cell extravasation: Demonstration of synergy between activation of CXCR3 and the T cell receptor

Molecular Immunology

Volumn 47, Issue 2-3, 2009, Pages 485-492

  Newton, Peter ^a   O'Boyle, Graeme ^a   Jenkins, Yvonne ^a   Ali, Simi ^a   Kirby, John A ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

CXCR3; Endothelium; T cell receptor

Indexed keywords

CD3 ANTIGEN; CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; CROSS LINKING; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INFLAMMATION; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ADULT; ANTIGENS, CD3; CELL LINE; CELL PROLIFERATION; CHEMOTAXIS; CROSS-LINKING REAGENTS; ENDOTHELIAL CELLS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; LYMPHOCYTE ACTIVATION; MODELS, IMMUNOLOGICAL; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, CXCR3; REPRODUCIBILITY OF RESULTS; T-LYMPHOCYTES;

EID: 70450224094     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.08.021     Document Type: Article

References (39)

1. Adams D.H., and Shaw S. Leucocyte-endothelial interactions and regulation of leucocyte migration. Lancet 343 (1994) 831-836
2. Al-Lamki R.S., Bradley J.R., and Pober J.S. Endothelial cells in allograft rejection. Transplantation 86 (2008) 1340-1348
3. Alon R., and Ley K. Cells on the run: shear-regulated integrin activation in leukocyte rolling and arrest on endothelial cells. Curr. Opin. Cell Biol. 20 (2008) 525-532
4. Bacon K.B., Premack B.A., Gardner P., and Schall T.J. Activation of dual T cell signaling pathways by the chemokine RANTES. Science 269 (1995) 1727-1730
5. Batard P., Szollosi J., Luescher I., Cerottini J.C., MacDonald R., and Romero P. Use of phycoerythrin and allophycocyanin for fluorescence resonance energy transfer analyzed by flow cytometry: advantages and limitations. Cytometry 48 (2002) 97-105
6. Campbell D.J., Kim C.H., and Butcher E.C. Chemokines in the systemic organization of immunity. Immunol. Rev. 195 (2003) 58-71
7. Carter N.M., Ali S., and Kirby J.A. Endothelial inflammation: the role of differential expression of N-deacetylase/N-sulphotransferase enzymes in alteration of the immunological properties of heparan sulphate. J. Cell. Sci. 116 (2003) 3591-3600
8. Contento R.L., Molon B., Boularan C., Pozzan T., Manes S., Marullo S., and Viola A. CXCR4-CCR5: a couple modulating T cell functions. Proc. Natl. Acad. Sci. U.S.A. 105 (2008) 10101-10106
9. Dar W.A., and Knechtle S.J. CXCR3-mediated T-cell chemotaxis involves ZAP-70 and is regulated by signalling through the T-cell receptor. Immunology 120 (2007) 467-485
10. De Clerck L.S., Bridts C.H., Mertens A.M., Moens M.M., and Stevens W.J. Use of fluorescent dyes in the determination of adherence of human leucocytes to endothelial cells and the effect of fluorochromes on cellular function. J. Immunol. Methods 172 (1994) 115-124
11. Dustin M.L., and Springer T.A. T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature 341 (1989) 619-624
12. Edgell C.J., McDonald C.C., and Graham J.B. Permanent cell line expressing human factor VIII-related antigen established by hybridization. Proc. Natl. Acad. Sci. U.S.A. 80 (1983) 3734-3737
13. Epler J.A., Liu R., Chung H., Ottoson N.C., and Shimizu Y. Regulation of beta 1 integrin-mediated adhesion by T cell receptor signaling involves ZAP-70 but differs from signaling events that regulate transcriptional activity. J. Immunol. 165 (2000) 4941-4949
14. Gasser O., Schmid T.A., Zenhaeusern G., and Hess C. Cyclooxygenase regulates cell surface expression of CXCR3/1-storing granules in human CD4+ T cells. J. Immunol. 177 (2006) 8806-8812
15. Greening J.E., Tree T.I., Kotowicz K.T., van Halteren A.G., Roep B.O., Klein N.J., and Peakman M. Processing and presentation of the islet autoantigen GAD by vascular endothelial cells promotes transmigration of autoreactive T-cells. Diabetes 52 (2003) 717-725
16. Hancock W.W., Lu B., Gao W., Csizmadia V., Faia K., King J.A., Smiley S.T., Ling M., Gerard N.P., and Gerard C. Requirement of the chemokine receptor CXCR3 for acute allograft rejection. J. Exp. Med. 192 (2000) 1515-1520
17. Hardy L.A., Booth T.A., Lau E.K., Handel T.M., Ali S., and Kirby J.A. Examination of MCP-1 (CCL2) partitioning and presentation during transendothelial leukocyte migration. Lab. Invest. 84 (2004) 81-90
18. Huppa J.B., and Davis M.M. T-cell-antigen recognition and the immunological synapse. Nat. Rev. Immunol. 3 (2003) 973-983
19. Kremer K.N., Humphreys T.D., Kumar A., Qian N.X., and Hedin K.E. Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1 alpha/CXCL12 chemokine. J. Immunol. 171 (2003) 360-367
20. Kumar A., Humphreys T.D., Kremer K.N., Bramati P.S., Bradfield L., Edgar C.E., and Hedin K.E. CXCR4 physically associates with the T cell receptor to signal in T cells. Immunity 25 (2006) 213-224
21. Ley K., Laudanna C., Cybulsky M.I., and Nourshargh S. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat. Rev. Immunol. 7 (2007) 678-689
22. Loetscher M., Gerber B., Loetscher P., Jones S.A., Piali L., Clark-Lewis I., Baggiolini M., and Moser B. Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J. Exp. Med. 184 (1996) 963-969
23. Luster A.D., and Ravetch J.V. Biochemical characterization of a gamma interferon-inducible cytokine (IP-10). J. Exp. Med. 166 (1987) 1084-1097
24. Manes T.D., and Pober J.S. Antigen presentation by human microvascular endothelial cells triggers ICAM-1-dependent transendothelial protrusion by, and fractalkine-dependent transendothelial migration of, effector memory CD4+ T cells. J. Immunol. 180 (2008) 8386-8392
25. Manes T.D., Shiao S.L., Dengler T.J., and Pober J.S. TCR signaling antagonizes rapid IP-10-mediated transendothelial migration of effector memory CD4+ T cells. J. Immunol. 178 (2007) 3237-3243
26. Marelli-Berg F.M., Frasca L., Weng L., Lombardi G., and Lechler R.I. Antigen recognition influences transendothelial migration of CD4+ T cells. J. Immunol. 162 (1999) 696-703
27. Molon B., Gri G., Bettella M., Gomez-Mouton C., Lanzavecchia A., Martinez A.C., Manes S., and Viola A. T cell costimulation by chemokine receptors. Nat. Immunol. 6 (2005) 465-471
28. Nanki T., and Lipsky P.E. Cutting edge: stromal cell-derived factor-1 is a costimulator for CD4+ T cell activation. J. Immunol. 164 (2000) 5010-5014
29. Ranjbaran H., Wang Y., Manes T.D., Yakimov A.O., Akhtar S., Kluger M.S., Pober J.S., and Tellides G. Heparin displaces interferon-gamma-inducible chemokines (IP-10, I-TAC, and Mig) sequestered in the vasculature and inhibits the transendothelial migration and arterial recruitment of T cells. Circulation 114 (2006) 1293-1300
30. Romagnani P. From basic science to clinical practice: use of cytokines and chemokines as therapeutic targets in renal diseases. J. Nephrol. 18 (2005) 229-233
31. Sana T.R., Janatpour M.J., Sathe M., McEvoy L.M., and McClanahan T.K. Microarray analysis of primary endothelial cells challenged with different inflammatory and immune cytokines. Cytokine 29 (2005) 256-269
32. Sato W., Aranami T., and Yamamura T. Cutting edge: human Th17 cells are identified as bearing CCR2+CCR5- phenotype. J. Immunol. 178 (2007) 7525-7529
33. Savage C.O., Brooks C.J., Harcourt G.C., Picard J.K., King W., Sansom D.M., and Willcox N. Human vascular endothelial cells process and present autoantigen to human T cell lines. Int. Immunol. 7 (1995) 471-479
34. Savinov A.Y., Wong F.S., and Chervonsky A.V. IFN-gamma affects homing of diabetogenic T cells. J. Immunol. 167 (2001) 6637-6643
35. Savinov A.Y., Wong F.S., Stonebraker A.C., and Chervonsky A.V. Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells. J. Exp. Med. 197 (2003) 643-656
36. Shiao S.L., Kirkiles-Smith N.C., Shepherd B.R., McNiff J.M., Carr E.J., and Pober J.S. Human effector memory CD4+ T cells directly recognize allogeneic endothelial cells in vitro and in vivo. J. Immunol. 179 (2007) 4397-4404
37. Tay S.S., McCormack A., Lawson C., and Rose M.L. IFN-gamma reverses the stop signal allowing migration of antigen-specific T cells into inflammatory sites. J. Immunol. 170 (2003) 3315-3322
38. Van Wauwe J.P., De Mey J.R., and Goossens J.G. OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties. J. Immunol. 124 (1980) 2708-2713
39. Ward S.G., and Marelli-Berg F.M. Mechanisms of chemokine and antigen-dependent T-lymphocyte navigation. Biochem. J. 418 (2009) 13-27