Surface-bound chemokines capture and prime T cells for synapse formation

Nature Immunology

Volumn 7, Issue 10, 2006, Pages 1101-1108

  Friedman, Rachel S ^a   Jacobelli, Jordan ^a   Krummel, Matthew F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR7; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; SECONDARY LYMPHOID TISSUE CHEMOKINE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CELL ADHESION; CELL SURFACE; CONTROLLED STUDY; DENDRITIC CELL; IMMUNITY; LYMPH NODE; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SYNAPSE; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD; CELL ADHESION; CELL ADHESION MOLECULES; CELL COMMUNICATION; CHEMOKINE CCL21; CHEMOKINES; CHEMOKINES, CC; DENDRITIC CELLS; INTERCELLULAR ADHESION MOLECULE-1; LIGANDS; LYMPH NODES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MICE; MICE, INBRED STRAINS; MICE, MUTANT STRAINS; RECEPTORS, CCR7; RECEPTORS, CHEMOKINE; T-LYMPHOCYTES;

EID: 33748866330     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1384     Document Type: Article

References (36)

1. Miller, M.J., Wei, S.H., Parker, I. & Cahalan, M.D. Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science 296, 1869-1873 (2002).
2. Mempel, T.R., Henrickson, S.E. & von Andrian, U.H. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 427, 154-159 (2004).
3. + T cell activation by dendritic cells in lymph nodes. J. Exp. Med. 200, 847-856 (2004).
4. Cyster, J.G. Chemokines and cell migration in secondary lymphoid organs. Science 286, 2098-2102 (1999).
5. Wülfing, C. et al. Kinetics and extent of T cell activation as measured with the calcium signal. J. Exp. Med. 185, 1815-1825 (1997).
6. Lee, K.H. et al. T cell receptor signaling precedes immunological synapse formation. Science 295, 1539-1542 (2002).
7. Grakoui, A. et al. The immunological synapse: A molecular machine that controls T cell activation. Science 285, 221-226 (1999).
8. Krummel, M.F., Sjaastad, M.D., Wülfing, C. & Davis, M.M. Differential assembly of CD3ζ and CD4 during T cell activation. Science 289, 1349-1352 (2000).
9. Wulfing, C. et al. Costimulation and endogenous MHC ligands contribute to T cell recognition. Nat. Immunol. 3, 42-47 (2002).
10. Monks, C.R., Freiberg, B.A., Kupfer, H., Sciaky, N. & Kupfer, A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395, 82-86 (1998).
11. Dustin, M.L., Bromley, S.K., Kan, Z., Peterson, D.A. & Unanue, E.R. Antigen receptor engagement delivers a stop signal to migrating T lymphocytes. Proc. Natl. Acad. Sci. USA 94, 3909-3913 (1997).
12. Negulescu, P.A., Krasieva, T.B., Khan, A., Kerschbaum, H.H. & Cahalan, M.D. Polarity of T cell shape, motility, and sensitivity to antigen. Immunity 4, 421-430 (1996).
13. Jacobelli, J., Chmura, S.A., Buxton, D.B., Davis, M.M. & Krummel, M.F. A single class II myosin modulates T cell motility and stopping but not synapse assembly. Nat. Immunol. 5, 531-538 (2004).
14. Laudanna, C., Campbell, J.J. & Butcher, E.C. Role of Rho in chemoattractant-activated leukocyte adhesion through integrins. Science 271, 981-983 (1996).
15. Campbell, J.J. et al. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science 279, 381-384 (1998).
16. 2 integrin affinity and mobility changes: Differential regulation and roles in lymphocyte arrest under flow. Immunity 13, 759-769 (2000).
17. + T cells. Cell. Immunol. 231, 75-84 (2004).
18. Molon, B. et al. T cell costimulation by chemokine receptors. Nat. Immunol. 6, 465-471 (2005).
19. Bromley, S.K., Peterson, D.A., Gunn, M.D. & Dustin, M.L. Cutting edge: hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation. J. Immunol. 165, 15-19 (2000).
20. Rot, A. Neutrophil attractant/activation protein-1 (interleukin-8) induces in vitro neutrophil migration by haptotactic mechanism. Eur. J. Immunol. 23, 303-306 (1993).
21. Proudfoot, A.E. et al. Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines. Proc. Natl. Acad. Sci. USA 100, 1885-1890 (2003).
22. Shamri, R. et al. Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines. Nat. Immunol. 6, 497-506 (2005).
23. Bromley, S.K. & Dustin, M.L. Stimulation of naive T-cell adhesion and immunological synapse formation by chemokine-dependent and -independent mechanisms. Immunology 106, 289-298 (2002).
24. Dulyaninova, N.G., Malashkevich, V.N., Almo, S.C. & Bresnick, A.R. Regulation of myosin-IIA assembly and Mts1 binding by heavy chain phosphorylation. Biochemistry 44, 6867-6876 (2005).
25. Friedman, R.S., Jacobelli, J. & Krummel, M.F. Mechanisms of T cell motility and arrest: Deciphering the relationship between intra- and extracellular determinants. Semin. Immunol. 17, 387-399 (2005).
26. Ngo, V.N., Tang, H.L. & Cyster, J.G. Epstein-Barr virus-induced molecule 1 ligand chemokine is expressed by dendritic cells in lymphoid tissues and strongly attracts naive T cells and activated B cells. J. Exp. Med. 188, 181-191 (1998).
27. 2+ signaling. Proc. Natl. Acad. Sci. USA 96, 8471-8476 (1999).
28. Lau, E.K. et al. Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: Implications for structure and function in vivo. J. Biol. Chem. 279, 22294-22305 (2004).
29. Luther, S.A., Tang, H.L., Hyman, P.L., Farr, A.G. & Cyster, J.G. Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse. Proc. Natl. Acad. Sci. USA 97, 12694-12699 (2000).
30. Forster, R. et al. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99, 23-33 (1999).
31. Sallusto, F. et al. Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells. Eur. J. Immunol. 29, 2037-2045 (1999).
32. + T lymphocytes primed by myeloid or plasmacytoid dendritic cells. Eur. J. Immunol. 33, 474-482 (2003).
33. Kaiser, A., Donnadieu, E., Abastado, J.P., Trautmann, A. & Nardin, A. CC chemokine ligand 19 secreted by mature dendritic cells increases naive T cell scanning behavior and their response to rare cognate antigen. J. Immunol. 175, 2349-2356 (2005).
34. Okada, T. et al. Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. PLoS Biol. 3, e150 (2005).
35. + T cell-dendritic cell interaction. Nature 440, 890-895 (2006).
36. Richie, L.I. et al. Imaging synapse formation during thymocyte selection: Inability of CD3ζ to form a stable central accumulation during negative selection. Immunity 16, 595-606 (2002).