Intravenous lipid infusion induces endoplasmic reticulum stress in endothelial cells and blood mononuclear cells of healthy adults

Journal of the American Heart Association

Volumn 5, Issue 1, 2016, Pages 1-10

  Tampakakis, Emmanouil ^a   Tabit, Corey E ^b   Holbrook, Monika ^b   Linder, Erika A ^b   Berk, Brittany D ^b   Frame, Alissa A ^b   Bretón Romero, Rosa ^b   Fetterman, Jessica L ^b   Gokce, Noyan ^b   Vita, Joseph A ^b   Hamburg, Naomi M ^b  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endoplasmic reticulum stress; Endothelium; Free fatty acids; Leukocyte

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; FATTY ACID; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; MEMBRANE PROTEIN; MESSENGER RNA; PHOSPHOINOSITOL REQUIRING KINASE 1; PHOSPHOTRANSFERASE; PROTEIN GADD34; PROTEIN IRE1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; ANTICOAGULANT AGENT; ATF6 PROTEIN, HUMAN; BIOLOGICAL MARKER; DDIT3 PROTEIN, HUMAN; EMULSION; ERN1 PROTEIN, HUMAN; HEPARIN; PHOSPHOLIPID; PHOSPHOPROTEIN PHOSPHATASE 1; PPP1R15A PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE; SOYBEAN OIL; SOYBEAN OIL, PHOSPHOLIPID EMULSION; XBP1 PROTEIN, HUMAN;

ADULT; ARTICLE; CELLULAR DISTRIBUTION; CHOLESTEROL BLOOD LEVEL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIUM CELL; EXPERIMENTAL DESIGN; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INFUSION; INTRAVENOUS LIPID INFUSION; LEUKOCYTE; MALE; MOLECULAR DYNAMICS; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RISK FACTOR; VASCULAR ENDOTHELIAL CELL; ADMINISTRATION AND DOSAGE; BLOOD; DRUG EFFECTS; EMULSION; GENE EXPRESSION REGULATION; GENETICS; HYPEREMIA; INTRAVENOUS DRUG ADMINISTRATION; LEG; METABOLISM; MICROCIRCULATION; MONONUCLEAR CELL; PATHOPHYSIOLOGY; PHOSPHORYLATION; TIME FACTOR; VASCULARIZATION; YOUNG ADULT;

ACTIVATING TRANSCRIPTION FACTOR 6; ADULT; ANTICOAGULANTS; BIOMARKERS; EMULSIONS; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; ENDOTHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; HEALTHY VOLUNTEERS; HEPARIN; HUMANS; HYPEREMIA; INFUSIONS, INTRAVENOUS; LEG; LEUKOCYTES, MONONUCLEAR; MALE; MICROCIRCULATION; PHOSPHOLIPIDS; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; PROTEIN-SERINE-THREONINE KINASES; SOYBEAN OIL; TIME FACTORS; TRANSCRIPTION FACTOR CHOP; X-BOX BINDING PROTEIN 1; YOUNG ADULT;

EID: 84998546801     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.115.002574     Document Type: Article

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