Acute and chronic effects of a 24-hour intravenous triglyceride emulsion challenge on plasma lecithin:cholesterol acyltransferase, phospholipid transfer protein, and cholesteryl ester transfer protein activities

Journal of Lipid Research

Volumn 40, Issue 8, 1999, Pages 1459-1466

  Riemens, S C ^a   Van Tol, A ^b   Sluiter, W J ^a   Dullaart, R P F ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b NONE

Author keywords

CETP; Insulin; LCAT; PLTP; Triglyceride emulsion

Indexed keywords

CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; PHOSPHOLIPID; PHOSPHOLIPID TRANSFER PROTEIN; PROTEIN; TRIACYLGLYCEROL;

ADULT; ARTICLE; CHOLESTEROL ESTERIFICATION; HUMAN; HUMAN EXPERIMENT; LIPID DIET; LIPID METABOLISM; MALE; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

CARRIER PROTEINS; CHOLESTEROL ESTER TRANSFER PROTEINS; DRUG COMBINATIONS; FAT EMULSIONS, INTRAVENOUS; GLYCOPROTEINS; HUMANS; INFUSIONS, INTRAVENOUS; INSULIN; LIPOPROTEINS, LDL; MALE; MEMBRANE PROTEINS; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE; PHOSPHATIDYLCHOLINES; PHOSPHOLIPID TRANSFER PROTEINS; PHOSPHOLIPIDS; SORBITOL; TRIGLYCERIDES;

EID: 0032777073     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. Jansen, H., A. Van Tol, and W. C. Hulsmann. 1980. On the metabolic function of heparin-releasable liver lipase. Biorhem. Biophys. Res. Commun. 92: 53-59.
2. Albers, J. J., C. H. Chen, and J. L. Adolphson. 1981. Lecithin: cholesterol acyltransfe rase (LCAT) mass: its relationship to LCAT activity and cholesterol esterification rate. J. Lipid Res. 22: 1206-1213.
3. Eisenberg, S. 1984. High density lipoprotein metabolism. J. Lipid Res. 25: 1017-1058.
4. Taskinen, M. R. 1987. Lipoprotein lipase in diabetes. Diabetes/Metab. Rev. 3: 551-570.
5. Dullaart, R. P. F., J. E. M. Groener, and D. W. Erkelens. 1991. Cholesteryl ester transfer between lipoproteins. Diabetes. Nutr. Metab. 14: 329-343.
6. Tall, A. R. 1993. Plasma cholesteryl ester transfer protein. J. Lipid Res. 34: 1255-1274.
7. Bruce, C., and A. R. Tall. 1995. Cholesteryl ester transfer proteins, reverse cholesterol transport, and atherosclerosis. Curr. Opin. Lipidol. 6: 306-311.
8. Cramp, D. G., and T. R. Tickner. 1978. The integrative role of lecithin:cholesterol acyl transferase in triglyceride clearance. Scand. J. Clin. Lab. Invest. 38 (Suppl. 150): 115-117.
9. Tollefson, J. H., S. Ravnik, and J. J. Albers. 1988. Isolation and characterization of a phospholipid transfer protein (LTP-II) from human plasma. J. Lipid Res. 29: 1593-1602.
10. Nishida, H. I., and T. Nishida. 1997. Phospholipid transfer protein mediates transfer of not only phosphatidylcholine but also cholesterol from phosphatidylcholine-cholesterol vesicles to high density lipoproteins. J. Biol. Chem. 272: 6959-6964.
11. Riemens, S. C., A. Van Tol, W. J. Sluiter, and R. P. F. Dullaart. 1998. Elevated plasma cholesteryl ester transfer in NIDDM: relationships with apolipoprotein B-containing lipoproteins and phospholipid transfer protein. Atherosclerosis. 140: 71-79.
12. Jauhiainen, M., J. Metso, R. Pahlman, S. Blomqvist, A. Van Tol, and C. Ehnholm. 1993. Human plasma phospholipid transfer protein causes high density lipoprotein conversion. J. Biol. Chem. 268: 4032-4036.
13. Tu, A. Y., H. I. Nishida, and T. Nishida. 1993. High density lipoprotein conversion mediated by human plasma phospholipid transfer protein. J. Biol. Chem. 268: 23098-23105.
14. Havel, R. J., J. P. Kane, and M. L. Kashyap. 1973. Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man. J. Clin. Invest. 52: 32-38.
15. Groot, P. H. E., and L. M. Scheek. 1984. Effects of fat ingestion on high density lipoprotein profiles in human sera. J. Lipid Res. 25: 684-692.
16. Sakuma, N., C. Lin, Y. Matsumoto, R. Ikeuchi, T. Ichikawa, H. Hirata, Y. Noguchi, and T. Fujinami. 1988. Changes of HDL subfraction concentration and particle size by intralipid in vivo. Atherosclerosis. 74: 91-98.
17. Dullaart, R. P. F., J. E. M. Groener, H. Van Wijk, W. J. Sluiter, and D. W. Erkelens. 1989. Alimentary lipemia-induced redistribution of cholesteryl ester between lipoproteins. Studies in normolipidemic, combined hyperlipidemic and hypercholesterolemic men. Arteriosclerosis. 9: 614-622.
18. Groener, J. E. M., L. M. Scheck, E. Van Ramshorst, X. H. Krauss, and A. Van Tol. 1998. Delayed increase in high density lipoprotein-phospholipids after ingestion of a fat load in normolipidemic patients with coronary artery disease. Atherosclerosis. 137: 311-319.
19. Taskinen, M. R., E. A. Nikkilä, T. Kuusi, and I. Tulikoura. 1983. Changes of high density lipoprotein subfraction concentration and composition by intralipid in vivo and by lipolysis of intralipid in vitro. Arteriosclerosis. 3: 607-615.
20. Hailer, S., and G. Wolfram. 1986. Influence of artificial fat emulsions on the composition of serum lipoproteins in humans. Am. J. Clin. Nutr. 43: 225-233.
21. Hailer, S., G. Wolfram, and N. Zöllner. 1987. Changes in serum lipoproteins in humans following the infusion of a fat emulsion containing medium- and long-chain triglycerides. Eur. J. Clin. Invest. 17: 402-407.
22. Norby, G., and K. R. Norum. 1978. Aspects of the role of lecithin:cholesterol acyl transferase in metabolism of triglycerides. Scand. J. Clin. Lab. Invest. 38, Suppl. 150: 111-114.
23. Marcel, Y. L. and C. Vezina. 1973. Lecithin:cholesterol acyltransferase of human plasma - role of chylomicrons, very low, and high density lipoproteins in the reaction. J. Biol. Chem. 248: 8254-8259.
24. Rose, H. G., and J. Juliano. 1977. Regulation of plasma lecithin:cholesterol acyltransferase. II. Activation during alimentary lipemia. J. Lab. Clin. Med. 89: 524-532.
25. Mero, N., A. Van Tol, L. M. Scheek, T. Van Gent, C. Labeur, M. Rosseneu, and M. R. Taskinen. 1998. Decreased postprandial high density lipoprotein cholesterol and apolipoproteins A-I and E in normolipidemic smoking men: relations with lipid transfer proteins and LCAT activities. J. Lipid Res. 39: 1493-1502.
26. Goel, R., M. Hamosh, G. E. Stohl, T. R. Henderson, M. L. Spear, and P. Hamosh. 1995. Plasma lecithin:cholesterol acyl transferase and plasma lipolytic activity in pre-term infants given total parental nutrition with 10% or 20% Intralipid. Acta Paediatr. 84: 1060-1064.
27. Marcel, Y. L., R. McPherson, M. Hogue, H. Czarnecka, Z. Zawadzki, P. K. Weech, M. E. Whitlock, A. R. Tall, and R. Milne. 1990. Distribution and concentration of cholesteryl ester transfer protein in plasma of normolipemic subjects. J. Clin. Invest. 85: 10-17.
28. Föger, B., A. Ritsch, A. Doblinger, H. Wessels, and J. R. Patsch. 1996. Relationship of plasma cholesteryl ester transfer protein to HDL cholesterol. Studies in normotriglyceridemia and moderate hypertriglyceridemia. Arterioscler. Thromb. Vasc. Biol. 16: 1430-1436.
29. Lassel, T. S., M. Guérin, S. Auboiron, M. J. Chapman, and B. Guy-Grand. 1998. Preferential cholesteryl ester acceptors among triglyceride-rich lipoproteins during alimentary lipemia in normolipidemic subjects. Arterioscler. Thromb. Vasc. Biol. 18: 65-74.
30. Van Tol, A., J. J. M. Ligtenberg, S. C. Riemens, T. W. Van Haeften, W. D. Reitsma, and R. P. F. Dullaart. 1997. Lowering of plasma phospholipid transfer protein activity by acute hyperglycaemia-induced hyperinsulinaemia in healthy men. Scand. J. Clin. Lab. Invest. 57: 147-158.
31. Riemens, S. C., A. Van Tol, W. J. Sluiter, and R. P. F. Dullaart. 1998. Plasma phospholipid transfer protein activity is related to insulin resistance and altered free fatty acid and triglycerides: impaired acute lowering by insulin in obese Type II diabetic patients. Diabetologia. 41: 929-934.
32. Malmström, R., C. J. Packard, M. Caslake, D. Bedford, P. Stewart, H. Yki-Järvinen, J. Shepherd, and M. R. Taskinen. 1997. Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM. Diabetologia. 40: 454-462.
33. Jensen, M. D., and V. J. Heiling. 1991. Heated hand vein blood is satisfactory for measurements during free fatty acid kinetic studies. Metabolism. 40: 406-409.
34. Demacker, P. N., A. G. Hijmans, H. E. Vos-Janssen, A. Van't Laar, and A. P. Jansen. 1980. A study of the use of polyethylene glycol in estimating cholesterol in high-density lipoprotein. Clin. Chem. 26: 1775-1779.
35. Groener, J. E. M., R. W. Pelton, and G. M. Kostner. 1986. Improved estimation of cholesteryl ester transfer/exchange activity in serum or plasma. Clin. Chem. 32: 283-286.
36. Speijer, H., J. E. M. Groener, E. Van Ramshorst, and A. Van Tol. 1991. Different locations of cholesteryl ester transfer protein and phospholipid transfer protein activities in plasma. Atherosclerosis. 90: 159-168.
37. Dullaart, R. P. F., W. J. Sluiter, L. D. Dikkeschei, K. Hoogenberg, and A. Van Tol. 1994. Effect of adiposity on plasma lipid transfer protein activities: a possible link between insulin resistance and high density lipoprotein metabolism. Eur. J. Clin. Invest. 24: 188-194.
38. Floren, C. H., C. H. Chen, J. Franzen, and J. J. Albers. 1987. Lecithin: cholesterol acyltransferase in liver disease. Scand. J. Clin. Lab. Invest. 47: 613-617.
39. Hannuksela, M., Y. L. Marcel, Y. A. Kesäniemi, and M. J. Savolainen. 1992. Reducti on in the concentration and activity of plasma cholesteryl ester transfer protein by alcohol. J. Lipid Res. 33: 737-744.
40. Jansen, H., W. Hop, A. Van Tol, A. V. G. Bruschke, and J. C. Birkenhager. 1994. Hepatic lipase and lipoprotein lipase are not major determinants of the low density lipoprotein subclass pattern in human subjects with coronary heart disease. Atherosclerosis. 107: 45-54.
41. Taskinen, M. R., and T. Kuusi, 1987. Enzymes involved in triglyceride hydrolysis. Baillières. Clin. Endocrinol. Metab. 1: 639-666.
42. Kissebah, A. J., and G. Schectman. 1987. Hormones and lipoprotein metabolism. Baillières. Clin. Endocrinol. Metab. 1: 699-725.
43. Lewis, G. F., K. D. Uffelman, L. W. Szeto, B. Weller, and G. Steiner. 1995. Interaction between free fatty acids and insulin in the acute control of very low density lipoprotein production in humans. J. Clin. Invest. 95: 158-166.
44. Groop, L. C., and E. Ferrannini. 1993. Insulin action and substrate competition. Baillières. Clin. Endocrinol. Metab. 7: 1007-1032.
45. Jiang, X., and C. Bruce. 1995. Regulation of murine plasma phospholipid transfer protein activity and mRNA levels by lipopolysaccharide and high cholesterol diet. J. Biol. Chem. 270: 17133-17138.
46. Martin, R. J., P. W. Cornelly, D. Nancoo, N. Wood, L. J. Zhang, G. Maguire, E. Quinet, A. R. Tall, Y. L. Marcel, and R. McPherson. 1993. Cholesterylester transfer protein and high density lipoprotein responses to cholesterol feeding in men: relationship to apolipoprotein E genotype. J. Lipid Res. 34: 437-446.
47. Oliveira, H. C. F., R. A. Chouinard, L. B. Agellon, C. Bruce, L. Ma, A. Walsh, J. L. Breslow, and A. R. Tall. 1996. Human cholesteryl ester transfer protein gene proximal promotor contains dietary cholesterol positive responsive elements and mediates expression in small intestine and periphery while predominant liver and spleen expression is controlled by 5′-distal sequences. Cis-acting sequences mapped in transgenic mice. J. Biol. Chem. 271: 31831-31838.
48. Griffin, E., W. C. Breckenridge, A. Kuksis, M. H. Bryan, and A. Angel. 1979. Appearance and characterization of lipoprotein X during continuous Intralipid infusions in the neonate. J. Clin. Invest. 64: 1703-1712.
49. Deckelbaum, R. J., R. Ramakrishnan, S. Eisenberg, T. Olivecrona, and G. Bengtsson-Olivecrona. 1992. Triacylglycerol and phospholipid hydrolysis in human plasma lipoproteins: role of lipoprotein and hepatic lipase. Biochemistry. 31: 8544-8551.
50. Weinberg, R. B., and A. M. Scanu, 1982. In vitro reciprocal exchange of apoproteins and nonpolar lipids between human high density lipoproteins and an artificial triglyceride-phospholipid emulsion (Intralipid). Atherosclerosis. 44: 141-152.
51. Castro, G. R., and C. J. Fielding, 1985. Effects of postprandial lipemia on plasma cholesterol metabolism. J. Clin. Invest. 75: 874-882.
52. Tall, A. R., E. Granot, R. Brocia, I. Tabas, G. Hesler, K. Williams, and M. Denko. 1987. Accelerated transfer of cholesteryl esters in dyslipidemic plasma. Role of cholesteryl ester transfer protein. J. Clin. Invest. 79: 1217-1225.
53. Mann, C. J., F. T. Yen, A. M. Grant, and B. E. Bihain. 1991. Mechanism of plasma cholesteryl ester transfer in hypertriglyceridemia. J. Clin. Invest. 88: 2059-2066.
54. Fielding, C. J. 1978. Metabolism of cholesterol-rich chylomicrons. Mechanism of binding and uptake of cholesteryl esters by the vascular bed of the perfused rat heart. J. Clin. Invest. 62: 141-151.
55. Zilversmit, D. B. 1979. Atherogenesis: a postprandial phenomenon. Circulation. 60: 473-485.
56. Glomset, J. A. 1968. The plasma lecithin:holesterol acyltransferase reaction. J. Lipid Res. 9: 155-167.
57. Castro, G. R., and C. J. Fielding. 1988. Early incorporation of cell-derived cholesterol into pre-beta-migrating high density lipoprotein. Biochemistry. 27: 25-29.
58. 1-HDL. Biochim. Biophys. Acta. 1301: 255-262.
59. Jiang, X., O. L. Francone, C. Bruce, R. Milne, J. Mar, A. Walsh, J. L. Breslow, and A. R. Tall. 1996. Increased preβ-high density lipoprotein, apolipoprotein AI, and phospholipid in mice expressing the human phospholipid transfer protein and human apolipoprotein AI transgenes. J. Clin. Invest. 96: 2373-2380.
60. Föger, B., S. Santamarina-Fojo, R. D. Shamburek, C. L. Parrot, G. D. Talley, and H. B. Brewer. 1997. Plasma phospholipid transfer protein. Adenovirus-mediated overexpression in mice leads to decreased plasma high density lipoprotein (HDL) and enhanced hepatic uptake of phospholipids and cholesteryl esters from HDL. J. Biol. Chem. 272: 27393-27400.
61. Syvänne, M., G. Castro, G. Dengremont, C. De Geitere, M. Jauhiainen, C. Ehnholm, S. Michelagnoli, G. Franceschini, J. Kahri, and M. R. Taskinen. 1996. Cholesterol efflux from Fu5AH hepatoma cells induced by plasma of subjects with or without coronary artery disease and non-insulin-dependent diabetes: importance of LpA-I:A-II particles and phospholipid transfer assay. Atherosclerosis. 127: 245-253.