-
1
-
-
47949114114
-
Integrins in angiogenesis and lymphangiogenesis
-
Avraamides, C.J., Garmy-Susini, B., Varner, J.A., Integrins in angiogenesis and lymphangiogenesis. Nat. Rev. Cancer 8 (2008), 604–617.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 604-617
-
-
Avraamides, C.J.1
Garmy-Susini, B.2
Varner, J.A.3
-
2
-
-
68949183227
-
Ena/VASP: towards resolving a pointed controversy at the barbed end
-
Bear, J.E., Gertler, F.B., Ena/VASP: towards resolving a pointed controversy at the barbed end. J. Cell Sci. 122 (2009), 1947–1953.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 1947-1953
-
-
Bear, J.E.1
Gertler, F.B.2
-
3
-
-
84942063845
-
The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development
-
Bebee, T.W., Park, J.W., Sheridan, K.I., Warzecha, C.C., Cieply, B.W., Rohacek, A.M., Xing, Y., Carstens, R.P., The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development. eLife, 4, 2015.
-
(2015)
eLife
, vol.4
-
-
Bebee, T.W.1
Park, J.W.2
Sheridan, K.I.3
Warzecha, C.C.4
Cieply, B.W.5
Rohacek, A.M.6
Xing, Y.7
Carstens, R.P.8
-
4
-
-
0032953451
-
Epithelial-mesenchymal transformation in the embryonic heart is mediated through distinct pertussis toxin-sensitive and TGFbeta signal transduction mechanisms
-
Boyer, A.S., Erickson, C.P., Runyan, R.B., Epithelial-mesenchymal transformation in the embryonic heart is mediated through distinct pertussis toxin-sensitive and TGFbeta signal transduction mechanisms. Dev. Dyn. 214 (1999), 81–91.
-
(1999)
Dev. Dyn.
, vol.214
, pp. 81-91
-
-
Boyer, A.S.1
Erickson, C.P.2
Runyan, R.B.3
-
5
-
-
84896701604
-
The RNA-binding protein Rbfox2: an essential regulator of EMT-driven alternative splicing and a mediator of cellular invasion
-
Braeutigam, C., Rago, L., Rolke, A., Waldmeier, L., Christofori, G., Winter, J., The RNA-binding protein Rbfox2: an essential regulator of EMT-driven alternative splicing and a mediator of cellular invasion. Oncogene 33 (2014), 1082–1092.
-
(2014)
Oncogene
, vol.33
, pp. 1082-1092
-
-
Braeutigam, C.1
Rago, L.2
Rolke, A.3
Waldmeier, L.4
Christofori, G.5
Winter, J.6
-
6
-
-
84917738647
-
Prognostic impact of alternative splicing-derived hMENA isoforms in resected, node-negative, non-small-cell lung cancer
-
Bria, E., Di Modugno, F., Sperduti, I., Iapicca, P., Visca, P., Alessandrini, G., Antoniani, B., Pilotto, S., Ludovini, V., Vannucci, J., Bellezza, G., Sidoni, A., Tortora, G., Radisky, D.C., Crino, L., Cognetti, F., Facciolo, F., Mottolese, M., Milella, M., Nistico, P., Prognostic impact of alternative splicing-derived hMENA isoforms in resected, node-negative, non-small-cell lung cancer. Oncotarget 5 (2014), 11054–11063.
-
(2014)
Oncotarget
, vol.5
, pp. 11054-11063
-
-
Bria, E.1
Di Modugno, F.2
Sperduti, I.3
Iapicca, P.4
Visca, P.5
Alessandrini, G.6
Antoniani, B.7
Pilotto, S.8
Ludovini, V.9
Vannucci, J.10
Bellezza, G.11
Sidoni, A.12
Tortora, G.13
Radisky, D.C.14
Crino, L.15
Cognetti, F.16
Facciolo, F.17
Mottolese, M.18
Milella, M.19
Nistico, P.20
more..
-
7
-
-
79952227361
-
CD44 splice isoform switching in human and mouse epithelium is essential for epithelial–mesenchymal transition and breast cancer progression
-
Brown, R.L., Reinke, L.M., Damerow, M.S., Perez, D., Chodosh, L.A., Yang, J., Cheng, C., CD44 splice isoform switching in human and mouse epithelium is essential for epithelial–mesenchymal transition and breast cancer progression. J. Clin. Invest. 121 (2011), 1064–1074.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1064-1074
-
-
Brown, R.L.1
Reinke, L.M.2
Damerow, M.S.3
Perez, D.4
Chodosh, L.A.5
Yang, J.6
Cheng, C.7
-
8
-
-
0029875911
-
The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies
-
Buckanovich, R.J., Yang, Y.Y., Darnell, R.B., The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies. J. Neurosci. 16 (1996), 1114–1122.
-
(1996)
J. Neurosci.
, vol.16
, pp. 1114-1122
-
-
Buckanovich, R.J.1
Yang, Y.Y.2
Darnell, R.B.3
-
9
-
-
0033784843
-
The transcription factor snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression
-
Cano, A., Perez-Moreno, M.A., Rodrigo, I., Locascio, A., Blanco, M.J., del Barrio, M.G., Portillo, F., Nieto, M.A., The transcription factor snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2 (2000), 76–83.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 76-83
-
-
Cano, A.1
Perez-Moreno, M.A.2
Rodrigo, I.3
Locascio, A.4
Blanco, M.J.5
del Barrio, M.G.6
Portillo, F.7
Nieto, M.A.8
-
10
-
-
84922798594
-
Regulation of epithelial–mesenchymal transition in breast cancer cells by cell contact and adhesion
-
Cichon, M.A., Nelson, C.M., Radisky, D.C., Regulation of epithelial–mesenchymal transition in breast cancer cells by cell contact and adhesion. Cancer Inform. 14 (2015), 1–13.
-
(2015)
Cancer Inform.
, vol.14
, pp. 1-13
-
-
Cichon, M.A.1
Nelson, C.M.2
Radisky, D.C.3
-
11
-
-
84860498816
-
Suppression of the epithelial–mesenchymal transition by Grainyhead-like-2
-
Cieply, B., Riley, P.T., Pifer, P.M., Widmeyer, J., Addison, J.B., Ivanov, A.V., Denvir, J., Frisch, S.M., Suppression of the epithelial–mesenchymal transition by Grainyhead-like-2. Cancer Res. 72 (2012), 2440–2453.
-
(2012)
Cancer Res.
, vol.72
, pp. 2440-2453
-
-
Cieply, B.1
Riley, P.T.2
Pifer, P.M.3
Widmeyer, J.4
Addison, J.B.5
Ivanov, A.V.6
Denvir, J.7
Frisch, S.M.8
-
12
-
-
0034964418
-
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
-
Comijn, J., Berx, G., Vermassen, P., Verschueren, K., van Grunsven, L., Bruyneel, E., Mareel, M., Huylebroeck, D., van Roy, F., The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol. Cell 7 (2001), 1267–1278.
-
(2001)
Mol. Cell
, vol.7
, pp. 1267-1278
-
-
Comijn, J.1
Berx, G.2
Vermassen, P.3
Verschueren, K.4
van Grunsven, L.5
Bruyneel, E.6
Mareel, M.7
Huylebroeck, D.8
van Roy, F.9
-
13
-
-
0242708621
-
A core function for p120-catenin in cadherin turnover
-
Davis, M.A., Ireton, R.C., Reynolds, A.B., A core function for p120-catenin in cadherin turnover. J. Cell Biol. 163 (2003), 525–534.
-
(2003)
J. Cell Biol.
, vol.163
, pp. 525-534
-
-
Davis, M.A.1
Ireton, R.C.2
Reynolds, A.B.3
-
14
-
-
84873050284
-
Regulatory networks defining EMT during cancer initiation and progression
-
De Craene, B., Berx, G., Regulatory networks defining EMT during cancer initiation and progression. Nat. Rev. Cancer 13 (2013), 97–110.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 97-110
-
-
De Craene, B.1
Berx, G.2
-
15
-
-
12344270322
-
Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes
-
de Kok, J.B., Roelofs, R.W., Giesendorf, B.A., Pennings, J.L., Waas, E.T., Feuth, T., Swinkels, D.W., Span, P.N., Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes. Lab. Invest. 85 (2005), 154–159.
-
(2005)
Lab. Invest.
, vol.85
, pp. 154-159
-
-
de Kok, J.B.1
Roelofs, R.W.2
Giesendorf, B.A.3
Pennings, J.L.4
Waas, E.T.5
Feuth, T.6
Swinkels, D.W.7
Span, P.N.8
-
16
-
-
79960760202
-
Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing
-
Dellago, H., Loscher, M., Ajuh, P., Ryder, U., Kaisermayer, C., Grillari-Voglauer, R., Fortschegger, K., Gross, S., Gstraunthaler, A., Borth, N., Eisenhaber, F., Lamond, A.I., Grillari, J., Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing. Biochem. J. 438 (2011), 81–91.
-
(2011)
Biochem. J.
, vol.438
, pp. 81-91
-
-
Dellago, H.1
Loscher, M.2
Ajuh, P.3
Ryder, U.4
Kaisermayer, C.5
Grillari-Voglauer, R.6
Fortschegger, K.7
Gross, S.8
Gstraunthaler, A.9
Borth, N.10
Eisenhaber, F.11
Lamond, A.I.12
Grillari, J.13
-
17
-
-
84869767975
-
Splicing program of human MENA produces a previously undescribed isoform associated with invasive, mesenchymal-like breast tumors
-
Di Modugno, F., Iapicca, P., Boudreau, A., Mottolese, M., Terrenato, I., Perracchio, L., Carstens, R.P., Santoni, A., Bissell, M.J., Nistico, P., Splicing program of human MENA produces a previously undescribed isoform associated with invasive, mesenchymal-like breast tumors. Proc. Natl. Acad. Sci. USA 109 (2012), 19280–19285.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 19280-19285
-
-
Di Modugno, F.1
Iapicca, P.2
Boudreau, A.3
Mottolese, M.4
Terrenato, I.5
Perracchio, L.6
Carstens, R.P.7
Santoni, A.8
Bissell, M.J.9
Nistico, P.10
-
18
-
-
84861302942
-
Genome-wide determination of a broad ESRP-regulated posttranscriptional network by high-throughput sequencing
-
Dittmar, K.A., Jiang, P., Park, J.W., Amirikian, K., Wan, J., Shen, S., Xing, Y., Carstens, R.P., Genome-wide determination of a broad ESRP-regulated posttranscriptional network by high-throughput sequencing. Mol. Cell. Biol. 32 (2012), 1468–1482.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 1468-1482
-
-
Dittmar, K.A.1
Jiang, P.2
Park, J.W.3
Amirikian, K.4
Wan, J.5
Shen, S.6
Xing, Y.7
Carstens, R.P.8
-
19
-
-
11144322013
-
Expression of integrins and E-cadherin in squamous cell carcinomas of the head and neck
-
Eriksen, J.G., Steiniche, T., Sogaard, H., Overgaard, J., Expression of integrins and E-cadherin in squamous cell carcinomas of the head and neck. APMIS 112 (2004), 560–568.
-
(2004)
APMIS
, vol.112
, pp. 560-568
-
-
Eriksen, J.G.1
Steiniche, T.2
Sogaard, H.3
Overgaard, J.4
-
20
-
-
1042278129
-
Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase
-
Fiegen, D., Haeusler, L.C., Blumenstein, L., Herbrand, U., Dvorsky, R., Vetter, I.R., Ahmadian, M.R., Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase. J. Biol. Chem. 279 (2004), 4743–4749.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4743-4749
-
-
Fiegen, D.1
Haeusler, L.C.2
Blumenstein, L.3
Herbrand, U.4
Dvorsky, R.5
Vetter, I.R.6
Ahmadian, M.R.7
-
21
-
-
84948429460
-
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
-
Fischer, K.R., Durrans, A., Lee, S., Sheng, J., Li, F., Wong, S.T., Choi, H., El Rayes, T., Ryu, S., Troeger, J., Schwabe, R.F., Vahdat, L.T., Altorki, N.K., Mittal, V., Gao, D., Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance. Nature 527 (2015), 472–476.
-
(2015)
Nature
, vol.527
, pp. 472-476
-
-
Fischer, K.R.1
Durrans, A.2
Lee, S.3
Sheng, J.4
Li, F.5
Wong, S.T.6
Choi, H.7
El Rayes, T.8
Ryu, S.9
Troeger, J.10
Schwabe, R.F.11
Vahdat, L.T.12
Altorki, N.K.13
Mittal, V.14
Gao, D.15
-
22
-
-
0030592559
-
Mena, a relative of VASP and Drosophila enabled, is implicated in the control of microfilament dynamics
-
Gertler, F.B., Niebuhr, K., Reinhard, M., Wehland, J., Soriano, P., Mena, a relative of VASP and Drosophila enabled, is implicated in the control of microfilament dynamics. Cell 87 (1996), 227–239.
-
(1996)
Cell
, vol.87
, pp. 227-239
-
-
Gertler, F.B.1
Niebuhr, K.2
Reinhard, M.3
Wehland, J.4
Soriano, P.5
-
23
-
-
84899962484
-
Regulated splicing of the alpha6 integrin cytoplasmic domain determines the fate of breast cancer stem cells
-
Goel, H.L., Gritsko, T., Pursell, B., Chang, C., Shultz, L.D., Greiner, D.L., Norum, J.H., Toftgard, R., Shaw, L.M., Mercurio, A.M., Regulated splicing of the alpha6 integrin cytoplasmic domain determines the fate of breast cancer stem cells. Cell Rep. 7 (2014), 747–761.
-
(2014)
Cell Rep.
, vol.7
, pp. 747-761
-
-
Goel, H.L.1
Gritsko, T.2
Pursell, B.3
Chang, C.4
Shultz, L.D.5
Greiner, D.L.6
Norum, J.H.7
Toftgard, R.8
Shaw, L.M.9
Mercurio, A.M.10
-
24
-
-
60449117235
-
Identification of invasion specific splice variants of the cytoskeletal protein Mena present in mammary tumor cells during invasion in vivo
-
Goswami, S., Philippar, U., Sun, D., Patsialou, A., Avraham, J., Wang, W., Di Modugno, F., Nistico, P., Gertler, F.B., Condeelis, J.S., Identification of invasion specific splice variants of the cytoskeletal protein Mena present in mammary tumor cells during invasion in vivo. Clin. Exp. Metastasis 26 (2009), 153–159.
-
(2009)
Clin. Exp. Metastasis
, vol.26
, pp. 153-159
-
-
Goswami, S.1
Philippar, U.2
Sun, D.3
Patsialou, A.4
Avraham, J.5
Wang, W.6
Di Modugno, F.7
Nistico, P.8
Gertler, F.B.9
Condeelis, J.S.10
-
25
-
-
84899933287
-
Integrin alpha6A splice variant regulates proliferation and the Wnt/beta-catenin pathway in human colorectal cancer cells
-
Groulx, J.F., Giroux, V., Beausejour, M., Boudjadi, S., Basora, N., Carrier, J.C., Beaulieu, J.F., Integrin alpha6A splice variant regulates proliferation and the Wnt/beta-catenin pathway in human colorectal cancer cells. Carcinogenesis 35 (2014), 1217–1227.
-
(2014)
Carcinogenesis
, vol.35
, pp. 1217-1227
-
-
Groulx, J.F.1
Giroux, V.2
Beausejour, M.3
Boudjadi, S.4
Basora, N.5
Carrier, J.C.6
Beaulieu, J.F.7
-
26
-
-
0037131409
-
Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression
-
Guaita, S., Puig, I., Franci, C., Garrido, M., Dominguez, D., Batlle, E., Sancho, E., Dedhar, S., De Herreros, A.G., Baulida, J., Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression. J. Biol. Chem. 277 (2002), 39209–39216.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39209-39216
-
-
Guaita, S.1
Puig, I.2
Franci, C.3
Garrido, M.4
Dominguez, D.5
Batlle, E.6
Sancho, E.7
Dedhar, S.8
De Herreros, A.G.9
Baulida, J.10
-
27
-
-
84881491808
-
The possible role of Mena protein and its splicing-derived variants in embryogenesis, carcinogenesis, and tumor invasion: a systematic review of the literature
-
Gurzu, S., Ciortea, D., Ember, I., Jung, I., The possible role of Mena protein and its splicing-derived variants in embryogenesis, carcinogenesis, and tumor invasion: a systematic review of the literature. BioMed Res. Int., 2013, 2013, 365192.
-
(2013)
BioMed Res. Int.
, vol.2013
, pp. 365192
-
-
Gurzu, S.1
Ciortea, D.2
Ember, I.3
Jung, I.4
-
28
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan, D., Weinberg, R.A., Hallmarks of cancer: the next generation. Cell 144 (2011), 646–674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
29
-
-
66049131300
-
Decrypting the genomeʼs alternative messages
-
Hartmann, B., Valcarcel, J., Decrypting the genomeʼs alternative messages. Curr. Opin. Cell Biol. 21 (2009), 377–386.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 377-386
-
-
Hartmann, B.1
Valcarcel, J.2
-
30
-
-
0027537324
-
Biochemical characterization and tissue distribution of the A and B variants of the integrin alpha 6 subunit
-
Hogervorst, F., Admiraal, L.G., Niessen, C., Kuikman, I., Janssen, H., Daams, H., Sonnenberg, A., Biochemical characterization and tissue distribution of the A and B variants of the integrin alpha 6 subunit. J. Cell Biol. 121 (1993), 179–191.
-
(1993)
J. Cell Biol.
, vol.121
, pp. 179-191
-
-
Hogervorst, F.1
Admiraal, L.G.2
Niessen, C.3
Kuikman, I.4
Janssen, H.5
Daams, H.6
Sonnenberg, A.7
-
31
-
-
84868260259
-
Alternative splicing of fibroblast growth factor receptor IgIII loops in cancer
-
Holzmann, K., Grunt, T., Heinzle, C., Sampl, S., Steinhoff, H., Reichmann, N., Kleiter, M., Hauck, M., Marian, B., Alternative splicing of fibroblast growth factor receptor IgIII loops in cancer. J. Nucleic Acids, 2012, 2012, 950508.
-
(2012)
J. Nucleic Acids
, vol.2012
, pp. 950508
-
-
Holzmann, K.1
Grunt, T.2
Heinzle, C.3
Sampl, S.4
Steinhoff, H.5
Reichmann, N.6
Kleiter, M.7
Hauck, M.8
Marian, B.9
-
32
-
-
84945956284
-
Phosphorylation and isoform use in p120-catenin during development and tumorigenesis
-
Hong, J.Y., Oh, I.H., McCrea, P.D., Phosphorylation and isoform use in p120-catenin during development and tumorigenesis. Biochim. Biophys. Acta 1863 (2016), 102–114.
-
(2016)
Biochim. Biophys. Acta
, vol.1863
, pp. 102-114
-
-
Hong, J.Y.1
Oh, I.H.2
McCrea, P.D.3
-
33
-
-
84863203049
-
TGF-beta drives epithelial–mesenchymal transition through deltaEF1-mediated downregulation of ESRP
-
Horiguchi, K., Sakamoto, K., Koinuma, D., Semba, K., Inoue, A., Inoue, S., Fujii, H., Yamaguchi, A., Miyazawa, K., Miyazono, K., Saitoh, M., TGF-beta drives epithelial–mesenchymal transition through deltaEF1-mediated downregulation of ESRP. Oncogene 31 (2012), 3190–3201.
-
(2012)
Oncogene
, vol.31
, pp. 3190-3201
-
-
Horiguchi, K.1
Sakamoto, K.2
Koinuma, D.3
Semba, K.4
Inoue, A.5
Inoue, S.6
Fujii, H.7
Yamaguchi, A.8
Miyazawa, K.9
Miyazono, K.10
Saitoh, M.11
-
34
-
-
18744399547
-
A novel role for p120 catenin in E-cadherin function
-
Ireton, R.C., Davis, M.A., van Hengel, J., Mariner, D.J., Barnes, K., Thoreson, M.A., Anastasiadis, P.Z., Matrisian, L., Bundy, L.M., Sealy, L., Gilbert, B., van Roy, F., Reynolds, A.B., A novel role for p120 catenin in E-cadherin function. J. Cell Biol. 159 (2002), 465–476.
-
(2002)
J. Cell Biol.
, vol.159
, pp. 465-476
-
-
Ireton, R.C.1
Davis, M.A.2
van Hengel, J.3
Mariner, D.J.4
Barnes, K.5
Thoreson, M.A.6
Anastasiadis, P.Z.7
Matrisian, L.8
Bundy, L.M.9
Sealy, L.10
Gilbert, B.11
van Roy, F.12
Reynolds, A.B.13
-
35
-
-
84907483753
-
Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms
-
Ishii, H., Saitoh, M., Sakamoto, K., Kondo, T., Katoh, R., Tanaka, S., Motizuki, M., Masuyama, K., Miyazawa, K., Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms. J. Biol. Chem. 289 (2014), 27386–27399.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 27386-27399
-
-
Ishii, H.1
Saitoh, M.2
Sakamoto, K.3
Kondo, T.4
Katoh, R.5
Tanaka, S.6
Motizuki, M.7
Masuyama, K.8
Miyazawa, K.9
-
36
-
-
34247854948
-
Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells
-
Ivanov, I., Lo, K.C., Hawthorn, L., Cowell, J.K., Ionov, Y., Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells. Oncogene 26 (2007), 2873–2884.
-
(2007)
Oncogene
, vol.26
, pp. 2873-2884
-
-
Ivanov, I.1
Lo, K.C.2
Hawthorn, L.3
Cowell, J.K.4
Ionov, Y.5
-
37
-
-
84874685798
-
Transcriptomic analysis of PNN- and ESRP1-regulated alternative pre-mRNA splicing in human corneal epithelial cells
-
Joo, J.H., Correia, G.P., Li, J.L., Lopez, M.C., Baker, H.V., Sugrue, S.P., Transcriptomic analysis of PNN- and ESRP1-regulated alternative pre-mRNA splicing in human corneal epithelial cells. Invest. Ophthalmol. Vis. Sci. 54 (2013), 697–707.
-
(2013)
Invest. Ophthalmol. Vis. Sci.
, vol.54
, pp. 697-707
-
-
Joo, J.H.1
Correia, G.P.2
Li, J.L.3
Lopez, M.C.4
Baker, H.V.5
Sugrue, S.P.6
-
38
-
-
67650999875
-
The basics of epithelial–mesenchymal transition
-
Kalluri, R., Weinberg, R.A., The basics of epithelial–mesenchymal transition. J. Clin. Invest. 119 (2009), 1420–1428.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
39
-
-
0032104205
-
Molecular cloning of the human p120ctn catenin gene (CTNND1): expression of multiple alternatively spliced isoforms
-
Keirsebilck, A., Bonne, S., Staes, K., van Hengel, J., Nollet, F., Reynolds, A., van Roy, F., Molecular cloning of the human p120ctn catenin gene (CTNND1): expression of multiple alternatively spliced isoforms. Genomics 50 (1998), 129–146.
-
(1998)
Genomics
, vol.50
, pp. 129-146
-
-
Keirsebilck, A.1
Bonne, S.2
Staes, K.3
van Hengel, J.4
Nollet, F.5
Reynolds, A.6
van Roy, F.7
-
40
-
-
84957630871
-
Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer
-
Kikuchi, M., Yamashita, K., Waraya, M., Minatani, N., Ushiku, H., Kojo, K., Ema, A., Kosaka, Y., Katoh, H., Sengoku, N., Enomoto, T., Tanino, H., Sawanobori, M., Watanabe, M., Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer. Oncotarget 7 (2016), 1741–1753.
-
(2016)
Oncotarget
, vol.7
, pp. 1741-1753
-
-
Kikuchi, M.1
Yamashita, K.2
Waraya, M.3
Minatani, N.4
Ushiku, H.5
Kojo, K.6
Ema, A.7
Kosaka, Y.8
Katoh, H.9
Sengoku, N.10
Enomoto, T.11
Tanino, H.12
Sawanobori, M.13
Watanabe, M.14
-
41
-
-
11244283209
-
The role of fibroblast growth factors and their receptors in prostate cancer
-
Kwabi-Addo, B., Ozen, M., Ittmann, M., The role of fibroblast growth factors and their receptors in prostate cancer. Endocr. Relat. Cancer 11 (2004), 709–724.
-
(2004)
Endocr. Relat. Cancer
, vol.11
, pp. 709-724
-
-
Kwabi-Addo, B.1
Ozen, M.2
Ittmann, M.3
-
42
-
-
0035146628
-
The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing
-
Ladd, A.N., Charlet, N., Cooper, T.A., The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing. Mol. Cell. Biol. 21 (2001), 1285–1296.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 1285-1296
-
-
Ladd, A.N.1
Charlet, N.2
Cooper, T.A.3
-
43
-
-
59449096532
-
RNA-binding motif protein 35A is a novel tumor suppressor for colorectal cancer
-
Leontieva, O.V., Ionov, Y., RNA-binding motif protein 35A is a novel tumor suppressor for colorectal cancer. Cell Cycle 8 (2009), 490–497.
-
(2009)
Cell Cycle
, vol.8
, pp. 490-497
-
-
Leontieva, O.V.1
Ionov, Y.2
-
44
-
-
77955341365
-
Kidney development: two tales of tubulogenesis
-
Little, M., Georgas, K., Pennisi, D., Wilkinson, L., Kidney development: two tales of tubulogenesis. Curr. Top. Dev. Biol. 90 (2010), 193–229.
-
(2010)
Curr. Top. Dev. Biol.
, vol.90
, pp. 193-229
-
-
Little, M.1
Georgas, K.2
Pennisi, D.3
Wilkinson, L.4
-
45
-
-
62849128406
-
Ablation of p120-catenin enhances invasion and metastasis of human lung cancer cells
-
Liu, Y., Li, Q.-C., Miao, Y., Xu, H.-T., Dai, S.-D., Wei, Q., Dong, Q.-Z., Dong, X.-J., Zhao, Y., Zhao, C., Wang, E.-H., Ablation of p120-catenin enhances invasion and metastasis of human lung cancer cells. Cancer Sci. 100 (2009), 441–448.
-
(2009)
Cancer Sci.
, vol.100
, pp. 441-448
-
-
Liu, Y.1
Li, Q.-C.2
Miao, Y.3
Xu, H.-T.4
Dai, S.-D.5
Wei, Q.6
Dong, Q.-Z.7
Dong, X.-J.8
Zhao, Y.9
Zhao, C.10
Wang, E.-H.11
-
46
-
-
84923922085
-
Transcriptome-wide landscape of pre-mRNA alternative splicing associated with metastatic colonization
-
Lu, Z.-X., Huang, Q., Park, J.W., Shen, S., Lin, L., Tokheim, C.J., Henry, M.D., Xing, Y., Transcriptome-wide landscape of pre-mRNA alternative splicing associated with metastatic colonization. Mol. Cancer Res. 13 (2015), 305–318.
-
(2015)
Mol. Cancer Res.
, vol.13
, pp. 305-318
-
-
Lu, Z.-X.1
Huang, Q.2
Park, J.W.3
Shen, S.4
Lin, L.5
Tokheim, C.J.6
Henry, M.D.7
Xing, Y.8
-
47
-
-
84892163927
-
Exo70 isoform switching upon epithelial–mesenchymal transition mediates cancer cell invasion
-
Lu, H., Liu, J., Liu, S., Zeng, J., Ding, D., Carstens, R.P., Cong, Y., Xu, X., Guo, W., Exo70 isoform switching upon epithelial–mesenchymal transition mediates cancer cell invasion. Dev. Cell 27 (2013), 560–573.
-
(2013)
Dev. Cell
, vol.27
, pp. 560-573
-
-
Lu, H.1
Liu, J.2
Liu, S.3
Zeng, J.4
Ding, D.5
Carstens, R.P.6
Cong, Y.7
Xu, X.8
Guo, W.9
-
48
-
-
84895504291
-
Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin
-
Mallinjoud, P., Villemin, J.P., Mortada, H., Polay Espinoza, M., Desmet, F.O., Samaan, S., Chautard, E., Tranchevent, L.C., Auboeuf, D., Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin. Genome Res. 24 (2014), 511–521.
-
(2014)
Genome Res.
, vol.24
, pp. 511-521
-
-
Mallinjoud, P.1
Villemin, J.P.2
Mortada, H.3
Polay Espinoza, M.4
Desmet, F.O.5
Samaan, S.6
Chautard, E.7
Tranchevent, L.C.8
Auboeuf, D.9
-
49
-
-
43049165453
-
The epithelial–mesenchymal transition generates cells with properties of stem cells
-
Mani, S.A., Guo, W., Liao, M.J., Eaton, E.N., Ayyanan, A., Zhou, A.Y., Brooks, M., Reinhard, F., Zhang, C.C., Shipitsin, M., Campbell, L.L., Polyak, K., Brisken, C., Yang, J., Weinberg, R.A., The epithelial–mesenchymal transition generates cells with properties of stem cells. Cell 133 (2008), 704–715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
50
-
-
84977621648
-
The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma
-
Mizutani, A., Koinuma, D., Seimiya, H., Miyazono, K., The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma. Oncogene 35 (2015), 3514–3523.
-
(2015)
Oncogene
, vol.35
, pp. 3514-3523
-
-
Mizutani, A.1
Koinuma, D.2
Seimiya, H.3
Miyazono, K.4
-
51
-
-
9344222224
-
Transforming potential of alternatively spliced variants of fibroblast growth factor receptor 2 in human mammary epithelial cells
-
Moffa, A.B., Tannheimer, S.L., Ethier, S.P., Transforming potential of alternatively spliced variants of fibroblast growth factor receptor 2 in human mammary epithelial cells. Mol. Cancer Res. 2 (2004), 643–652.
-
(2004)
Mol. Cancer Res.
, vol.2
, pp. 643-652
-
-
Moffa, A.B.1
Tannheimer, S.L.2
Ethier, S.P.3
-
52
-
-
84871882783
-
Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response
-
Nagelkerke, A., Bussink, J., Mujcic, H., Wouters, B.G., Lehmann, S., Sweep, F.C., Span, P.N., Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response. Breast Cancer Res., 15, 2013, R2.
-
(2013)
Breast Cancer Res.
, vol.15
, pp. R2
-
-
Nagelkerke, A.1
Bussink, J.2
Mujcic, H.3
Wouters, B.G.4
Lehmann, S.5
Sweep, F.C.6
Span, P.N.7
-
53
-
-
84887024055
-
The PERK/ATF4/LAMP3-arm of the unfolded protein response affects radioresistance by interfering with the DNA damage response
-
Nagelkerke, A., Bussink, J., van der Kogel, A.J., Sweep, F.C., Span, P.N., The PERK/ATF4/LAMP3-arm of the unfolded protein response affects radioresistance by interfering with the DNA damage response. Radiother. Oncol. 108 (2013), 415–421.
-
(2013)
Radiother. Oncol.
, vol.108
, pp. 415-421
-
-
Nagelkerke, A.1
Bussink, J.2
van der Kogel, A.J.3
Sweep, F.C.4
Span, P.N.5
-
54
-
-
84869116723
-
p120-catenin binding masks an endocytic signal conserved in classical cadherins
-
Nanes, B.A., Chiasson-MacKenzie, C., Lowery, A.M., Ishiyama, N., Faundez, V., Ikura, M., Vincent, P.A., Kowalczyk, A.P., p120-catenin binding masks an endocytic signal conserved in classical cadherins. J. Cell Biol. 199 (2012), 365–380.
-
(2012)
J. Cell Biol.
, vol.199
, pp. 365-380
-
-
Nanes, B.A.1
Chiasson-MacKenzie, C.2
Lowery, A.M.3
Ishiyama, N.4
Faundez, V.5
Ikura, M.6
Vincent, P.A.7
Kowalczyk, A.P.8
-
55
-
-
85027941046
-
Hallmarks of alternative splicing in cancer
-
Oltean, S., Bates, D.O., Hallmarks of alternative splicing in cancer. Oncogene 33 (2014), 5311–5318.
-
(2014)
Oncogene
, vol.33
, pp. 5311-5318
-
-
Oltean, S.1
Bates, D.O.2
-
56
-
-
41649091906
-
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
-
Park, S.M., Gaur, A.B., Lengyel, E., Peter, M.E., The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev. 22 (2008), 894–907.
-
(2008)
Genes Dev.
, vol.22
, pp. 894-907
-
-
Park, S.M.1
Gaur, A.B.2
Lengyel, E.3
Peter, M.E.4
-
57
-
-
0038756636
-
Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions
-
Peinado, H., Quintanilla, M., Cano, A., Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J. Biol. Chem. 278 (2003), 21113–21123.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21113-21123
-
-
Peinado, H.1
Quintanilla, M.2
Cano, A.3
-
58
-
-
84913537715
-
Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration
-
Pignatelli, J., Goswami, S., Jones, J.G., Rohan, T.E., Pieri, E., Chen, X., Adler, E., Cox, D., Maleki, S., Bresnick, A., Gertler, F.B., Condeelis, J.S., Oktay, M.H., Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration. Sci. Signal., 7, 2014, ra112.
-
(2014)
Sci. Signal.
, vol.7
, pp. ra112
-
-
Pignatelli, J.1
Goswami, S.2
Jones, J.G.3
Rohan, T.E.4
Pieri, E.5
Chen, X.6
Adler, E.7
Cox, D.8
Maleki, S.9
Bresnick, A.10
Gertler, F.B.11
Condeelis, J.S.12
Oktay, M.H.13
-
59
-
-
51049084629
-
Human Mena+11a isoform serves as a marker of epithelial phenotype and sensitivity to epidermal growth factor receptor inhibition in human pancreatic cancer cell lines
-
Pino, M.S., Balsamo, M., Di Modugno, F., Mottolese, M., Alessio, M., Melucci, E., Milella, M., McConkey, D.J., Philippar, U., Gertler, F.B., Natali, P.G., Nistico, P., Human Mena+11a isoform serves as a marker of epithelial phenotype and sensitivity to epidermal growth factor receptor inhibition in human pancreatic cancer cell lines. Clin. Cancer Res. 14 (2008), 4943–4950.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 4943-4950
-
-
Pino, M.S.1
Balsamo, M.2
Di Modugno, F.3
Mottolese, M.4
Alessio, M.5
Melucci, E.6
Milella, M.7
McConkey, D.J.8
Philippar, U.9
Gertler, F.B.10
Natali, P.G.11
Nistico, P.12
-
60
-
-
84904750913
-
Regulation of alternative splicing of CD44 in cancer
-
Prochazka, L., Tesarik, R., Turanek, J., Regulation of alternative splicing of CD44 in cancer. Cell. Signal. 26 (2014), 2234–2239.
-
(2014)
Cell. Signal.
, vol.26
, pp. 2234-2239
-
-
Prochazka, L.1
Tesarik, R.2
Turanek, J.3
-
61
-
-
84901787644
-
Oncogenic roles of EMT-inducing transcription factors
-
Puisieux, A., Brabletz, T., Caramel, J., Oncogenic roles of EMT-inducing transcription factors. Nat. Cell Biol. 16 (2014), 488–494.
-
(2014)
Nat. Cell Biol.
, vol.16
, pp. 488-494
-
-
Puisieux, A.1
Brabletz, T.2
Caramel, J.3
-
62
-
-
84930418435
-
HPV16 E5 expression induces switching from FGFR2b to FGFR2c and epithelial–mesenchymal transition
-
Ranieri, D., Belleudi, F., Magenta, A., Torrisi, M.R., HPV16 E5 expression induces switching from FGFR2b to FGFR2c and epithelial–mesenchymal transition. Int. J. Cancer 137 (2015), 61–72.
-
(2015)
Int. J. Cancer
, vol.137
, pp. 61-72
-
-
Ranieri, D.1
Belleudi, F.2
Magenta, A.3
Torrisi, M.R.4
-
63
-
-
84958069027
-
Expression of the FGFR2 mesenchymal splicing variant in epithelial cells drives epithelial–mesenchymal transition
-
Ranieri, D., Rosato, B., Nanni, M., Magenta, A., Belleudi, F., Torrisi, M.R., Expression of the FGFR2 mesenchymal splicing variant in epithelial cells drives epithelial–mesenchymal transition. Oncotarget 7 (2015), 5440–5460.
-
(2015)
Oncotarget
, vol.7
, pp. 5440-5460
-
-
Ranieri, D.1
Rosato, B.2
Nanni, M.3
Magenta, A.4
Belleudi, F.5
Torrisi, M.R.6
-
64
-
-
84978942566
-
Grainyhead-like 2 downstream targets act to suppress EMT during neural tube closure
-
Ray, H.J., Niswander, L.A., Grainyhead-like 2 downstream targets act to suppress EMT during neural tube closure. Development 143 (2016), 1192–1204.
-
(2016)
Development
, vol.143
, pp. 1192-1204
-
-
Ray, H.J.1
Niswander, L.A.2
-
65
-
-
84867795377
-
Snail represses the splicing regulator epithelial splicing regulatory protein 1 to promote epithelial–mesenchymal transition
-
Reinke, L.M., Xu, Y., Cheng, C., Snail represses the splicing regulator epithelial splicing regulatory protein 1 to promote epithelial–mesenchymal transition. J. Biol. Chem. 287 (2012), 36435–36442.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 36435-36442
-
-
Reinke, L.M.1
Xu, Y.2
Cheng, C.3
-
66
-
-
84874189256
-
During embryogenesis, esrp1 expression is restricted to a subset of epithelial cells and is associated with splicing of a number of developmentally important genes
-
Revil, T., Jerome-Majewska, L.A., During embryogenesis, esrp1 expression is restricted to a subset of epithelial cells and is associated with splicing of a number of developmentally important genes. Dev. Dyn. 242 (2013), 281–290.
-
(2013)
Dev. Dyn.
, vol.242
, pp. 281-290
-
-
Revil, T.1
Jerome-Majewska, L.A.2
-
67
-
-
33845411513
-
p120-Catenin: past and present
-
Reynolds, A.B., p120-Catenin: past and present. Biochim. Biophys. Acta 1773 (2007), 2–7.
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 2-7
-
-
Reynolds, A.B.1
-
68
-
-
77951219259
-
Changes of telomerase activity by alternative splicing of full-length and beta variants of hTERT in breast cancer patients
-
Rha, S.Y., Jeung, H.C., Park, K.H., Kim, J.J., Chung, H.C., Changes of telomerase activity by alternative splicing of full-length and beta variants of hTERT in breast cancer patients. Oncol. Res. 18 (2009), 213–220.
-
(2009)
Oncol. Res.
, vol.18
, pp. 213-220
-
-
Rha, S.Y.1
Jeung, H.C.2
Park, K.H.3
Kim, J.J.4
Chung, H.C.5
-
69
-
-
0027992204
-
Alternative splicing in fibroblast growth factor receptor 2 is associated with induced epithelial–mesenchymal transition in rat bladder carcinoma cells
-
Savagner, P., Valles, A.M., Jouanneau, J., Yamada, K.M., Thiery, J.P., Alternative splicing in fibroblast growth factor receptor 2 is associated with induced epithelial–mesenchymal transition in rat bladder carcinoma cells. Mol. Biol. Cell. 5 (1994), 851–862.
-
(1994)
Mol. Biol. Cell.
, vol.5
, pp. 851-862
-
-
Savagner, P.1
Valles, A.M.2
Jouanneau, J.3
Yamada, K.M.4
Thiery, J.P.5
-
70
-
-
84883313434
-
p120-catenin in cancer—mechanisms, models and opportunities for intervention
-
Schackmann, R.C., Tenhagen, M., van de Ven, R.A., Derksen, P.W., p120-catenin in cancer—mechanisms, models and opportunities for intervention. J. Cell Sci. 126 (2013), 3515–3525.
-
(2013)
J. Cell Sci.
, vol.126
, pp. 3515-3525
-
-
Schackmann, R.C.1
Tenhagen, M.2
van de Ven, R.A.3
Derksen, P.W.4
-
71
-
-
0027065573
-
Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons
-
Screaton, G.R., Bell, M.V., Jackson, D.G., Cornelis, F.B., Gerth, U., Bell, J.I., Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc. Natl. Acad. Sci. USA 89 (1992), 12160–12164.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 12160-12164
-
-
Screaton, G.R.1
Bell, M.V.2
Jackson, D.G.3
Cornelis, F.B.4
Gerth, U.5
Bell, J.I.6
-
72
-
-
80052322960
-
An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype
-
Shapiro, I.M., Cheng, A.W., Flytzanis, N.C., Balsamo, M., Condeelis, J.S., Oktay, M.H., Burge, C.B., Gertler, F.B., An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype. PLoS Genet., 7, 2011, e1002218.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002218
-
-
Shapiro, I.M.1
Cheng, A.W.2
Flytzanis, N.C.3
Balsamo, M.4
Condeelis, J.S.5
Oktay, M.H.6
Burge, C.B.7
Gertler, F.B.8
-
73
-
-
11244313840
-
Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation
-
Singh, A., Karnoub, A.E., Palmby, T.R., Lengyel, E., Sondek, J., Der, C.J., Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation. Oncogene 23 (2004), 9369–9380.
-
(2004)
Oncogene
, vol.23
, pp. 9369-9380
-
-
Singh, A.1
Karnoub, A.E.2
Palmby, T.R.3
Lengyel, E.4
Sondek, J.5
Der, C.J.6
-
74
-
-
0036233040
-
Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation
-
Strutz, F., Zeisberg, M., Ziyadeh, F.N., Yang, C.Q., Kalluri, R., Muller, G.A., Neilson, E.G., Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation. Kidney Int. 61 (2002), 1714–1728.
-
(2002)
Kidney Int.
, vol.61
, pp. 1714-1728
-
-
Strutz, F.1
Zeisberg, M.2
Ziyadeh, F.N.3
Yang, C.Q.4
Kalluri, R.5
Muller, G.A.6
Neilson, E.G.7
-
75
-
-
77957262381
-
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
-
Taube, J.H., Herschkowitz, J.I., Komurov, K., Zhou, A.Y., Gupta, S., Yang, J., Hartwell, K., Onder, T.T., Gupta, P.B., Evans, K.W., Hollier, B.G., Ram, P.T., Lander, E.S., Rosen, J.M., Weinberg, R.A., Mani, S.A., Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc. Natl. Acad. Sci. USA 107 (2010), 15449–15454.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 15449-15454
-
-
Taube, J.H.1
Herschkowitz, J.I.2
Komurov, K.3
Zhou, A.Y.4
Gupta, S.5
Yang, J.6
Hartwell, K.7
Onder, T.T.8
Gupta, P.B.9
Evans, K.W.10
Hollier, B.G.11
Ram, P.T.12
Lander, E.S.13
Rosen, J.M.14
Weinberg, R.A.15
Mani, S.A.16
-
76
-
-
57849150788
-
Alternative splicing and disease
-
Tazi, J., Bakkour, N., Stamm, S., Alternative splicing and disease. Biochim. Biophys. Acta 1792 (2009), 14–26.
-
(2009)
Biochim. Biophys. Acta
, vol.1792
, pp. 14-26
-
-
Tazi, J.1
Bakkour, N.2
Stamm, S.3
-
77
-
-
70450198396
-
Epithelial–mesenchymal transitions in development and disease
-
Thiery, J.P., Acloque, H., Huang, R.Y., Nieto, M.A., Epithelial–mesenchymal transitions in development and disease. Cell 139 (2009), 871–890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
78
-
-
22244492306
-
Carcinoma invasion and metastasis: a role for epithelial–mesenchymal transition?
-
(discussion 5995)
-
Thompson, E.W., Newgreen, D.F., Tarin, D., Carcinoma invasion and metastasis: a role for epithelial–mesenchymal transition?. Cancer Res. 65 (2005), 5991–5995 (discussion 5995).
-
(2005)
Cancer Res.
, vol.65
, pp. 5991-5995
-
-
Thompson, E.W.1
Newgreen, D.F.2
Tarin, D.3
-
79
-
-
0028828282
-
Expression patterns of laminin receptor splice variants alpha 6A beta 1 and alpha 6B beta 1 suggest different roles in mouse development
-
Thorsteinsdottir, S., Roelen, B.A., Freund, E., Gaspar, A.C., Sonnenberg, A., Mummery, C.L., Expression patterns of laminin receptor splice variants alpha 6A beta 1 and alpha 6B beta 1 suggest different roles in mouse development. Dev. Dyn. 204 (1995), 240–258.
-
(1995)
Dev. Dyn.
, vol.204
, pp. 240-258
-
-
Thorsteinsdottir, S.1
Roelen, B.A.2
Freund, E.3
Gaspar, A.C.4
Sonnenberg, A.5
Mummery, C.L.6
-
80
-
-
84865755978
-
The accessible chromatin landscape of the human genome
-
Thurman, R.E., Rynes, E., Humbert, R., Vierstra, J., Maurano, M.T., Haugen, E., Sheffield, N.C., Stergachis, A.B., Wang, H., Vernot, B., Garg, K., John, S., Sandstrom, R., Bates, D., Boatman, L., Canfield, T.K., Diegel, M., Dunn, D., Ebersol, A.K., Frum, T., Giste, E., Johnson, A.K., Johnson, E.M., Kutyavin, T., Lajoie, B., Lee, B.K., Lee, K., London, D., Lotakis, D., Neph, S., Neri, F., Nguyen, E.D., Qu, H., Reynolds, A.P., Roach, V., Safi, A., Sanchez, M.E., Sanyal, A., Shafer, A., Simon, J.M., Song, L., Vong, S., Weaver, M., Yan, Y., Zhang, Z., Zhang, Z., Lenhard, B., Tewari, M., Dorschner, M.O., Hansen, R.S., Navas, P.A., Stamatoyannopoulos, G., Iyer, V.R., Lieb, J.D., Sunyaev, S.R., Akey, J.M., Sabo, P.J., Kaul, R., Furey, T.S., Dekker, J., Crawford, G.E., Stamatoyannopoulos, J.A., The accessible chromatin landscape of the human genome. Nature 489 (2012), 75–82.
-
(2012)
Nature
, vol.489
, pp. 75-82
-
-
Thurman, R.E.1
Rynes, E.2
Humbert, R.3
Vierstra, J.4
Maurano, M.T.5
Haugen, E.6
Sheffield, N.C.7
Stergachis, A.B.8
Wang, H.9
Vernot, B.10
Garg, K.11
John, S.12
Sandstrom, R.13
Bates, D.14
Boatman, L.15
Canfield, T.K.16
Diegel, M.17
Dunn, D.18
Ebersol, A.K.19
Frum, T.20
Giste, E.21
Johnson, A.K.22
Johnson, E.M.23
Kutyavin, T.24
Lajoie, B.25
Lee, B.K.26
Lee, K.27
London, D.28
Lotakis, D.29
Neph, S.30
Neri, F.31
Nguyen, E.D.32
Qu, H.33
Reynolds, A.P.34
Roach, V.35
Safi, A.36
Sanchez, M.E.37
Sanyal, A.38
Shafer, A.39
Simon, J.M.40
Song, L.41
Vong, S.42
Weaver, M.43
Yan, Y.44
Zhang, Z.45
Zhang, Z.46
Lenhard, B.47
Tewari, M.48
Dorschner, M.O.49
Hansen, R.S.50
Navas, P.A.51
Stamatoyannopoulos, G.52
Iyer, V.R.53
Lieb, J.D.54
Sunyaev, S.R.55
Akey, J.M.56
Sabo, P.J.57
Kaul, R.58
Furey, T.S.59
Dekker, J.60
Crawford, G.E.61
Stamatoyannopoulos, J.A.62
more..
-
81
-
-
84884666662
-
Epithelial splicing regulatory protein 1 is a favorable prognostic factor in pancreatic cancer that attenuates pancreatic metastases
-
Ueda, J., Matsuda, Y., Yamahatsu, K., Uchida, E., Naito, Z., Korc, M., Ishiwata, T., Epithelial splicing regulatory protein 1 is a favorable prognostic factor in pancreatic cancer that attenuates pancreatic metastases. Oncogene 33 (2014), 4485–4495.
-
(2014)
Oncogene
, vol.33
, pp. 4485-4495
-
-
Ueda, J.1
Matsuda, Y.2
Yamahatsu, K.3
Uchida, E.4
Naito, Z.5
Korc, M.6
Ishiwata, T.7
-
82
-
-
34250702714
-
Wnt pathway-related gene expression during malignant progression in ulcerative colitis
-
van Dekken, H., Wink, J.C., Vissers, K.J., Franken, P.F., Ruud Schouten, W., J Hop, W.C., Kuipers, E.J., Fodde, R., Janneke van der Woude, C., Wnt pathway-related gene expression during malignant progression in ulcerative colitis. Acta Histochem. 109 (2007), 266–272.
-
(2007)
Acta Histochem.
, vol.109
, pp. 266-272
-
-
van Dekken, H.1
Wink, J.C.2
Vissers, K.J.3
Franken, P.F.4
Ruud Schouten, W.5
J Hop, W.C.6
Kuipers, E.J.7
Fodde, R.8
Janneke van der Woude, C.9
-
83
-
-
0346494761
-
GenePaint.org: an atlas of gene expression patterns in the mouse embryo
-
Visel, A., Thaller, C., Eichele, G., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 32 (2004), D552–D556.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. D552-D556
-
-
Visel, A.1
Thaller, C.2
Eichele, G.3
-
84
-
-
34548758543
-
Splicing in disease: disruption of the splicing code and the decoding machinery
-
Wang, G.S., Cooper, T.A., Splicing in disease: disruption of the splicing code and the decoding machinery. Nat. Rev. Genet. 8 (2007), 749–761.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 749-761
-
-
Wang, G.S.1
Cooper, T.A.2
-
85
-
-
79955865397
-
Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity
-
Wang, H., Zhou, M., Shi, B., Zhang, Q., Jiang, H., Sun, Y., Liu, J., Zhou, K., Yao, M., Gu, J., Yang, S., Mao, Y., Li, Z., Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity. Neoplasia 13 (2011), 461–471.
-
(2011)
Neoplasia
, vol.13
, pp. 461-471
-
-
Wang, H.1
Zhou, M.2
Shi, B.3
Zhang, Q.4
Jiang, H.5
Sun, Y.6
Liu, J.7
Zhou, K.8
Yao, M.9
Gu, J.10
Yang, S.11
Mao, Y.12
Li, Z.13
-
86
-
-
84866320228
-
Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT)
-
Warzecha, C.C., Carstens, R.P., Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT). Semin. Cancer Biol. 22 (2012), 417–427.
-
(2012)
Semin. Cancer Biol.
, vol.22
, pp. 417-427
-
-
Warzecha, C.C.1
Carstens, R.P.2
-
87
-
-
77957767273
-
An ESRP-regulated splicing programme is abrogated during the epithelial–mesenchymal transition
-
Warzecha, C.C., Jiang, P., Amirikian, K., Dittmar, K.A., Lu, H., Shen, S., Guo, W., Xing, Y., Carstens, R.P., An ESRP-regulated splicing programme is abrogated during the epithelial–mesenchymal transition. EMBO J. 29 (2010), 3286–3300.
-
(2010)
EMBO J.
, vol.29
, pp. 3286-3300
-
-
Warzecha, C.C.1
Jiang, P.2
Amirikian, K.3
Dittmar, K.A.4
Lu, H.5
Shen, S.6
Guo, W.7
Xing, Y.8
Carstens, R.P.9
-
88
-
-
61649087689
-
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing
-
Warzecha, C.C., Sato, T.K., Nabet, B., Hogenesch, J.B., Carstens, R.P., ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol. Cell 33 (2009), 591–601.
-
(2009)
Mol. Cell
, vol.33
, pp. 591-601
-
-
Warzecha, C.C.1
Sato, T.K.2
Nabet, B.3
Hogenesch, J.B.4
Carstens, R.P.5
-
89
-
-
77950552549
-
The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events
-
Warzecha, C.C., Shen, S., Xing, Y., Carstens, R.P., The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events. RNA Biol. 6 (2009), 546–562.
-
(2009)
RNA Biol.
, vol.6
, pp. 546-562
-
-
Warzecha, C.C.1
Shen, S.2
Xing, Y.3
Carstens, R.P.4
-
90
-
-
84871312342
-
Grhl2 determines the epithelial phenotype of breast cancers and promotes tumor progression
-
Xiang, X., Deng, Z., Zhuang, X., Ju, S., Mu, J., Jiang, H., Zhang, L., Yan, J., Miller, D., Zhang, H.G., Grhl2 determines the epithelial phenotype of breast cancers and promotes tumor progression. PLoS One, 7, 2012, e50781.
-
(2012)
PLoS One
, vol.7
, pp. e50781
-
-
Xiang, X.1
Deng, Z.2
Zhuang, X.3
Ju, S.4
Mu, J.5
Jiang, H.6
Zhang, L.7
Yan, J.8
Miller, D.9
Zhang, H.G.10
-
91
-
-
84901746783
-
Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing
-
Xu, Y., Gao, X.D., Lee, J.H., Huang, H., Tan, H., Ahn, J., Reinke, L.M., Peter, M.E., Feng, Y., Gius, D., Siziopikou, K.P., Peng, J., Xiao, X., Cheng, C., Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing. Genes Dev. 28 (2014), 1191–1203.
-
(2014)
Genes Dev.
, vol.28
, pp. 1191-1203
-
-
Xu, Y.1
Gao, X.D.2
Lee, J.H.3
Huang, H.4
Tan, H.5
Ahn, J.6
Reinke, L.M.7
Peter, M.E.8
Feng, Y.9
Gius, D.10
Siziopikou, K.P.11
Peng, J.12
Xiao, X.13
Cheng, C.14
-
92
-
-
59449090107
-
TGF-beta-induced epithelial to mesenchymal transition
-
Xu, J., Lamouille, S., Derynck, R., TGF-beta-induced epithelial to mesenchymal transition. Cell Res. 19 (2009), 156–172.
-
(2009)
Cell Res.
, vol.19
, pp. 156-172
-
-
Xu, J.1
Lamouille, S.2
Derynck, R.3
-
93
-
-
79952759697
-
Human transcriptome array for high-throughput clinical studies
-
Xu, W., Seok, J., Mindrinos, M.N., Schweitzer, A.C., Jiang, H., Wilhelmy, J., Clark, T.A., Kapur, K., Xing, Y., Faham, M., Storey, J.D., Moldawer, L.L., Maier, R.V., Tompkins, R.G., Wong, W.H., Davis, R.W., Xiao, W., Inflammation, Host Response to Injury Large-Scale Collaborative Research. Human transcriptome array for high-throughput clinical studies. Proc. Natl. Acad. Sci. USA 108 (2011), 3707–3712.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 3707-3712
-
-
Xu, W.1
Seok, J.2
Mindrinos, M.N.3
Schweitzer, A.C.4
Jiang, H.5
Wilhelmy, J.6
Clark, T.A.7
Kapur, K.8
Xing, Y.9
Faham, M.10
Storey, J.D.11
Moldawer, L.L.12
Maier, R.V.13
Tompkins, R.G.14
Wong, W.H.15
Davis, R.W.16
Xiao, W.17
-
94
-
-
84863321158
-
Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell
-
Yae, T., Tsuchihashi, K., Ishimoto, T., Motohara, T., Yoshikawa, M., Yoshida, G.J., Wada, T., Masuko, T., Mogushi, K., Tanaka, H., Osawa, T., Kanki, Y., Minami, T., Aburatani, H., Ohmura, M., Kubo, A., Suematsu, M., Takahashi, K., Saya, H., Nagano, O., Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell. Nat. Commun., 3, 2012, 883.
-
(2012)
Nat. Commun.
, vol.3
, pp. 883
-
-
Yae, T.1
Tsuchihashi, K.2
Ishimoto, T.3
Motohara, T.4
Yoshikawa, M.5
Yoshida, G.J.6
Wada, T.7
Masuko, T.8
Mogushi, K.9
Tanaka, H.10
Osawa, T.11
Kanki, Y.12
Minami, T.13
Aburatani, H.14
Ohmura, M.15
Kubo, A.16
Suematsu, M.17
Takahashi, K.18
Saya, H.19
Nagano, O.20
more..
-
95
-
-
49649116726
-
A p120 catenin isoform switch affects Rho activity, induces tumor cell invasion, and predicts metastatic disease
-
Yanagisawa, M., Huveldt, D., Kreinest, P., Lohse, C.M., Cheville, J.C., Parker, A.S., Copland, J.A., Anastasiadis, P.Z., A p120 catenin isoform switch affects Rho activity, induces tumor cell invasion, and predicts metastatic disease. J. Biol. Chem. 283 (2008), 18344–18354.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 18344-18354
-
-
Yanagisawa, M.1
Huveldt, D.2
Kreinest, P.3
Lohse, C.M.4
Cheville, J.C.5
Parker, A.S.6
Copland, J.A.7
Anastasiadis, P.Z.8
-
96
-
-
44449144396
-
Epithelial–mesenchymal transition: at the crossroads of development and tumor metastasis
-
Yang, J., Weinberg, R.A., Epithelial–mesenchymal transition: at the crossroads of development and tumor metastasis. Dev. Cell 14 (2008), 818–829.
-
(2008)
Dev. Cell
, vol.14
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
97
-
-
84941243013
-
Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
-
Ye, X., Tam, W.L., Shibue, T., Kaygusuz, Y., Reinhardt, F., Ng Eaton, E., Weinberg, R.A., Distinct EMT programs control normal mammary stem cells and tumour-initiating cells. Nature 525 (2015), 256–260.
-
(2015)
Nature
, vol.525
, pp. 256-260
-
-
Ye, X.1
Tam, W.L.2
Shibue, T.3
Kaygusuz, Y.4
Reinhardt, F.5
Ng Eaton, E.6
Weinberg, R.A.7
-
98
-
-
84945566252
-
Epithelial–mesenchymal plasticity: a central regulator of cancer progression
-
Ye, X., Weinberg, R.A., Epithelial–mesenchymal plasticity: a central regulator of cancer progression. Trends Cell. Biol. 25 (2015), 675–686.
-
(2015)
Trends Cell. Biol.
, vol.25
, pp. 675-686
-
-
Ye, X.1
Weinberg, R.A.2
-
99
-
-
84948407218
-
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
-
Zheng, X., Carstens, J.L., Kim, J., Scheible, M., Kaye, J., Sugimoto, H., Wu, C.C., LeBleu, V.S., Kalluri, R., Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature 527 (2015), 525–530.
-
(2015)
Nature
, vol.527
, pp. 525-530
-
-
Zheng, X.1
Carstens, J.L.2
Kim, J.3
Scheible, M.4
Kaye, J.5
Sugimoto, H.6
Wu, C.C.7
LeBleu, V.S.8
Kalluri, R.9
-
100
-
-
79953042645
-
CD44: can a cancer-initiating cell profit from an abundantly expressed molecule?
-
Zoller, M., CD44: can a cancer-initiating cell profit from an abundantly expressed molecule?. Nat. Rev. Cancer 11 (2011), 254–267.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 254-267
-
-
Zoller, M.1
|