-
1
-
-
5444256238
-
Self-renewal and solid tumor stem cells
-
Al-Hajj, M., Clarke, M. F. Self-renewal and solid tumor stem cells. Oncogene 23, 7274-7282 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 7274-7282
-
-
Al-Hajj, M.1
Clarke, M.F.2
-
2
-
-
60649110684
-
Cancer stem cells in solid tumors: An overview
-
O'Brien, C. A., Kreso, A., Dick, J. E. Cancer stem cells in solid tumors: an overview. Semin. Radiat. Oncol. 19, 71-77 (2009).
-
(2009)
Semin. Radiat. Oncol
, vol.19
, pp. 71-77
-
-
O'Brien, C.A.1
Kreso, A.2
Dick, J.E.3
-
3
-
-
84862517728
-
Cancer stem cells: Current status and evolving complexities
-
Visvader, J. E., Lindeman, G. J. Cancer stem cells: current status and evolving complexities. Cell Stem Cell 10, 717-728 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 717-728
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
4
-
-
79956351015
-
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
-
Chaffer, C. L. et al. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proc. Natl Acad. Sci. USA 108, 7950-7955 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 7950-7955
-
-
Chaffer, C.L.1
-
5
-
-
80051967505
-
Stochastic state transitions give rise to phenotypic equilibriumin populations of cancer cells
-
Gupta, P. B. et al. Stochastic state transitions give rise to phenotypic equilibriumin populations of cancer cells. Cell 146, 633-644 (2011).
-
(2011)
Cell
, vol.146
, pp. 633-644
-
-
Gupta, P.B.1
-
6
-
-
84884558125
-
Unravelling cancer stem cell potential
-
Beck, B., Blanpain, C. Unravelling cancer stem cell potential. Nature Rev. Cancer 13, 727-738 (2013).
-
(2013)
Nature Rev. Cancer
, vol.13
, pp. 727-738
-
-
Beck, B.1
Blanpain, C.2
-
7
-
-
84896125494
-
Evolution of the cancer stem cell model
-
Kreso, A., Dick, J. E. Evolution of the cancer stem cell model. Cell Stem Cell 14, 275-291 (2014).
-
(2014)
Cell Stem Cell
, vol.14
, pp. 275-291
-
-
Kreso, A.1
Dick, J.E.2
-
8
-
-
84857817163
-
SlugandSox9 cooperatively determine themammary stemcell state
-
Guo, W. et al. SlugandSox9 cooperatively determine themammary stemcell state. Cell 148, 1015-1028 (2012).
-
(2012)
Cell
, vol.148
, pp. 1015-1028
-
-
Guo, W.1
-
9
-
-
30144433093
-
Generation of a functionalmammary gland froma single stem cell
-
Shackleton,M. et al.Generation of a functionalmammary gland froma single stem cell. Nature 439, 84-88 (2006).
-
(2006)
Nature
, vol.439
, pp. 84-88
-
-
Shackleton, M.1
-
10
-
-
30144432901
-
Purification andunique properties ofmammary epithelial stemcells
-
Stingl, J. et al. Purification andunique properties ofmammary epithelial stemcells. Nature 439, 993-997 (2006).
-
(2006)
Nature
, vol.439
, pp. 993-997
-
-
Stingl, J.1
-
11
-
-
84922019806
-
Mammary stem cells havemyoepithelial cell properties
-
Prater, M. D. et al. Mammary stem cells havemyoepithelial cell properties. Nature Cell Biol. 16, 942-950 (2014).
-
(2014)
Nature Cell Biol
, vol.16
, pp. 942-950
-
-
Prater, M.D.1
-
12
-
-
0142244181
-
Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases
-
Lin, E. Y. et al. Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. Am. J. Pathol. 163, 2113-2126 (2003).
-
(2003)
Am. J. Pathol
, vol.163
, pp. 2113-2126
-
-
Lin, E.Y.1
-
13
-
-
84894581126
-
Collective invasion in breast cancer requires a conserved basal epithelial program
-
Cheung, K. J., Gabrielson, E., Werb, Z., Ewald, A. J. Collective invasion in breast cancer requires a conserved basal epithelial program. Cell 155, 1639-1651 (2013).
-
(2013)
Cell
, vol.155
, pp. 1639-1651
-
-
Cheung, K.J.1
Gabrielson, E.2
Werb, Z.3
Ewald, A.J.4
-
14
-
-
68349130357
-
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
-
Lim, E. et al. Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nature Med. 15, 907-913 (2009).
-
(2009)
Nature Med
, vol.15
, pp. 907-913
-
-
Lim, E.1
-
15
-
-
77956218241
-
BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
-
Molyneux, G. et al. BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell 7, 403-417 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 403-417
-
-
Molyneux, G.1
-
16
-
-
72749103664
-
Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis
-
Visvader, J. E. Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis. Genes Dev. 23, 2563-2577 (2009).
-
(2009)
Genes Dev
, vol.23
, pp. 2563-2577
-
-
Visvader, J.E.1
-
17
-
-
78751676408
-
Cells of origin in cancer
-
Visvader, J. E. Cells of origin in cancer. Nature 469, 314-322 (2011).
-
(2011)
Nature
, vol.469
, pp. 314-322
-
-
Visvader, J.E.1
-
18
-
-
0023713558
-
Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene
-
Muller, W. J., Sinn, E., Pattengale, P. K., Wallace, R.& Leder, P. Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell 54, 105-115 (1988).
-
(1988)
Cell
, vol.54
, pp. 105-115
-
-
Muller, W.J.1
Sinn, E.2
Pattengale, P.K.3
Wallace, R.4
Leder, P.5
-
19
-
-
0032587877
-
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation
-
Xu, X. et al. Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. Nature Genet. 22, 37-43 (1999).
-
(1999)
Nature Genet
, vol.22
, pp. 37-43
-
-
Xu, X.1
-
20
-
-
24944450362
-
The transcriptional repressor Snail promotes mammary tumor recurrence
-
Moody, S. E. et al. The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell 8, 197-209 (2005).
-
(2005)
Cancer Cell
, vol.8
, pp. 197-209
-
-
Moody, S.E.1
-
21
-
-
84909606776
-
Transient SNAIL1 expression is necessary for metastatic competence in breast cancer
-
Tran, H. D. et al. Transient SNAIL1 expression is necessary for metastatic competence in breast cancer. Cancer Res. 74, 6330-6340 (2014).
-
(2014)
Cancer Res
, vol.74
, pp. 6330-6340
-
-
Tran, H.D.1
-
22
-
-
76249084838
-
Smad signaling is required to maintain epigenetic silencing during breast cancer progression
-
Papageorgis, P. et al. Smad signaling is required to maintain epigenetic silencing during breast cancer progression. Cancer Res. 70, 968-978 (2010).
-
(2010)
Cancer Res
, vol.70
, pp. 968-978
-
-
Papageorgis, P.1
-
23
-
-
77953123909
-
An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like HER2 and luminal cancers
-
Natrajan, R. et al. An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers. Breast Cancer Res. Treat. 121, 575-589 (2010).
-
(2010)
Breast Cancer Res. Treat
, vol.121
, pp. 575-589
-
-
Natrajan, R.1
-
24
-
-
79151483638
-
An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis usingmicroarray data of1,809 patients
-
Gyorffy, B. et al. An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis usingmicroarray data of1,809 patients. Breast Cancer Res. Treat. 123, 725-731 (2010).
-
(2010)
Breast Cancer Res. Treat
, vol.123
, pp. 725-731
-
-
Gyorffy, B.1
-
25
-
-
0036513626
-
The snail superfamily of zinc-finger transcription factors
-
Nieto, M. A. The snail superfamily of zinc-finger transcription factors. Nature Rev. Mol. Cell Biol. 3, 155-166 (2002).
-
(2002)
Nature Rev. Mol. Cell Biol
, vol.3
, pp. 155-166
-
-
Nieto, M.A.1
-
26
-
-
84879983245
-
Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity
-
Chaffer, C. L. et al. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell 154, 61-74 (2013).
-
(2013)
Cell
, vol.154
, pp. 61-74
-
-
Chaffer, C.L.1
-
27
-
-
84881540768
-
The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance
-
Siebzehnrubl, F. A. et al. The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance. EMBO Mol. Med. 5, 1196-1212 (2013).
-
(2013)
EMBO Mol. Med
, vol.5
, pp. 1196-1212
-
-
Siebzehnrubl, F.A.1
-
28
-
-
73049110243
-
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
-
Wellner, U. et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nature Cell Biol. 11, 1487-1495 (2009).
-
(2009)
Nature Cell Biol
, vol.11
, pp. 1487-1495
-
-
Wellner, U.1
-
29
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery, J. P., Acloque, H., Huang, R. Y., Nieto, M. A. Epithelial-mesenchymal transitions in development and disease. Cell 139, 871-890 (2009).
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
30
-
-
0037131409
-
Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression
-
Guaita, S. et al. Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression. J. Biol. Chem. 277, 39209-39216 (2002)
-
(2002)
J. Biol. Chem
, vol.277
, pp. 39209-39216
-
-
Guaita, S.1
-
31
-
-
84883621632
-
Protein kinaseCa is a central signaling node and therapeutic target for breast cancer stem cells
-
Tam,W. L. et al. Protein kinaseCa is a central signaling node and therapeutic target for breast cancer stem cells. Cancer Cell 24, 347-364 (2013).
-
(2013)
Cancer Cell
, vol.24
, pp. 347-364
-
-
Tam, W.L.1
-
32
-
-
67650444760
-
ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
-
Hu, Y., Smyth, G. K. ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays. J. Immunol. Methods 347, 70-78 (2009).
-
(2009)
J. Immunol. Methods
, vol.347
, pp. 70-78
-
-
Hu, Y.1
Smyth, G.K.2
-
33
-
-
84885388198
-
An integrin-linked machinery of cytoskeletal regulation that enables experimental tumor initiation and metastatic colonization
-
Shibue, T., Brooks, M. W., Weinberg, R. A. An integrin-linked machinery of cytoskeletal regulation that enables experimental tumor initiation and metastatic colonization. Cancer Cell 24, 481-498 (2013).
-
(2013)
Cancer Cell
, vol.24
, pp. 481-498
-
-
Shibue, T.1
Brooks, M.W.2
Weinberg, R.A.3
-
34
-
-
25844508786
-
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation
-
Gupta, P. B. et al. The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nature Genet. 37, 1047-1054 (2005).
-
(2005)
Nature Genet
, vol.37
, pp. 1047-1054
-
-
Gupta, P.B.1
-
35
-
-
53849146020
-
Model-based analysis of ChIP-Seq (MACS)
-
Zhang, Y. et al. Model-based analysis of ChIP-Seq (MACS). Genome Biol. 9, R137 (2008).
-
(2008)
Genome Biol
, vol.9
, pp. R137
-
-
Zhang, Y.1
|