Splicing program of human MENA produces a previously undescribed isoform associated with invasive, mesenchymal-like breast tumors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 47, 2012, Pages 19280-19285

  Di Modugno, Francesca ^a   Iapicca, Pierluigi ^a   Boudreau, Aaron ^b,c   Mottolese, Marcella ^a   Terrenato, Irene ^a   Perracchio, Letizia ^a   Carstens, Russ P ^d   Santoni, Angela ^e   Bissell, Mina J ^b   Nisticò, Paola ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

EMT; ENAH; Splice variants

Indexed keywords

ACTIN; COMPLEMENTARY DNA; EPITHELIAL SPLICING REGULATORY PROTEIN 1; MENA PROTEIN; MESSENGER RNA; PLASMID DNA; REGULATOR PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; UVOMORULIN; VASODILATOR STIMULATED PHOSPHOPROTEIN;

ARTICLE; BREAST TUMOR; CANCER CELL CULTURE; CANCER INVASION; CELL TRANSFORMATION; CYTOSKELETON; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; GENE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MENA GENE; MESENCHYMAL EPITHELIAL TRANSITION; MESENCHYME CELL; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRECANCER; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACTIN CYTOSKELETON; ALTERNATIVE SPLICING; BREAST NEOPLASMS; CADHERINS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CLONING, MOLECULAR; DISEASE PROGRESSION; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MESODERM; MICROFILAMENT PROTEINS; MOLECULAR SEQUENCE DATA; NEOPLASM INVASIVENESS; PHENOTYPE; PROTEIN ISOFORMS; RNA-BINDING PROTEINS; TRANSFECTION; VIMENTIN;

EID: 84869767975     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1214394109     Document Type: Article

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