Author Correction: Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice (Nature Communications, (2016), 7, 1, (13344), 10.1038/ncomms13344);Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice

Nature Communications

Volumn 7, Issue , 2016, Pages

  Monnerat, Gustavo ^a   Alarcón, Micaela L ^a   Vasconcellos, Luiz R ^a   Hochman Mendez, Camila ^a   Brasil, Guilherme ^a   Bassani, Rosana A ^b   Casis, Oscar ^c   Malan, Daniela ^d   Travassos, Leonardo H ^a   Sepúlveda, Marisa ^e   Burgos, Juan Ignacio ^e   Vila Petroff, Martin ^e   Dutra, Fabiano F ^a   Bozza, Marcelo T ^a   Paiva, Claudia N ^a   Carvalho, Adriana Bastos ^a   Bonomo, Adriana ^a,f   Fleischmann, Bernd K ^d   De Carvalho, Antonio Carlos Campos ^a,g   Medei, Emiliano ^a,g  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^d UNIVERSITY OF BONN   (Germany)

^e FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

^f INSTITUTO OSWALDO CRUZ   (Brazil)

^g National Center for Structural Biology and Bioimaging   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TOLL LIKE RECEPTOR 2; ANTIRHEUMATIC AGENT; CASP1 PROTEIN, MOUSE; IL1B PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA CONVERTING ENZYME; NLRP3 PROTEIN, MOUSE; POTASSIUM; TLR2 PROTEIN, MOUSE;

BLOOD; CALCIUM; CARDIOVASCULAR DISEASE; CELLS AND CELL COMPONENTS; CHEMORECEPTION; DIABETES; OXIDATION; POTASSIUM; RODENT;

ACTION POTENTIAL DURATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETES MELLITUS; DISEASE SEVERITY; ENZYME METABOLISM; ENZYME PHOSPHORYLATION; FEMALE; HEART ARRHYTHMIA; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE TACHYCARDIA; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; METABOLIC DISORDER; MOUSE; NONHUMAN; POTASSIUM CURRENT; QT INTERVAL; QT PROLONGATION; ACTION POTENTIAL; ANIMAL; ANTAGONISTS AND INHIBITORS; COMPLICATION; EXPERIMENTAL DIABETES MELLITUS; GENETICS; HEART CONTRACTION; IMMUNOLOGY; METABOLISM; TRANSGENIC MOUSE;

MUS;

ACTION POTENTIALS; ANIMALS; ANTIRHEUMATIC AGENTS; ARRHYTHMIAS, CARDIAC; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CASPASE 1; DIABETES MELLITUS, EXPERIMENTAL; INFLAMMASOMES; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; MACROPHAGES; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; POTASSIUM; RECEPTORS, INTERLEUKIN-1; TACHYCARDIA, VENTRICULAR; TOLL-LIKE RECEPTOR 2;

EID: 84997270772     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-021-27508-w     Document Type: Erratum

References (70)

1. Martinon, F., Pétrilli, V., Mayor, A., Tardivel, A., Tschopp, J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440, 237-241 (2006).
2. Vilaysane, A. et al. The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. J. Am. Soc. Nephrol. 21, 1732-1744 (2010).
3. De Nardo, D., Latz, E. NLRP3 inflammasomes link inflammation and metabolic disease. Trends Immunol. 32, 373-379 (2011).
4. Grishman, E. K., White, P. C., Savani, R. C. Toll-like receptors, the NLRP3 inflammasome, interleukin-1b in the development and progression of type 1 diabetes. Pediatr. Res. 71, 626-632 (2012).
5. Kannel, W. B., McGee, D. L. Diabetes and cardiovascular risk factors: the Framingham study. Circulation 59, 8-13 (1979).
6. Preis, S. R. et al. Trends in cardiovascular disease risk factors in individuals with and without diabetes mellitus in the Framingham Heart Study. Circulation 120, 212-220 (2012).
7. Kahn, J. K., Sisson, J. C., Vinik, A. I. QT interval prolongation and sudden cardiac death in diabetic autonomic neuropathy. J. Clin. Endocrinol. Metab. 64, 751-754 (1987).
8. Magyar, J., Rusznák, Z., Szentesi, P., Szûcs, G., Kovács, L. Action potentials and potassium currents in rat ventricular muscle during experimental diabetes. J. Mol. Cell. Cardiol. 24, 841-853 (1992).
9. Tu, E., Twigg, S. M., Semsarian, C. Sudden death in type 1 diabetes: the mystery of the 'dead in bed' syndrome. Int. J. Cardiol. 138, 91-93 (2010).
10. El-Atat, F. A., McFarlane, S. I., Sowers, J. R., Bigger, J. T. Sudden cardiac death in patients with diabetes. Curr. Diab. Rep. 4, 187-193 (2004).
11. Lu, Z. et al. Increased persistent sodium current due to decreased PI3K signaling contributes to QT prolongation in the diabetic heart. Diabetes 62, 4257-4265 (2013).
12. Dasu, M. R., Devaraj, S., Zhao, L., Hwang, D. H., Jialal, I. High glucose induces toll-like receptor expression in human monocytes: mechanism of activation. Diabetes 57, 3090-3098 (2008).
13. Koenen, T. B. et al. Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1beta transcription in human adipose tissue. Diabetes 60, 517-524 (2011).
14. Niu, J., Gilliland, M. G., Jin, Z., Kolattukudy, P. E., Hoffman, W. H. MCP-1and IL-1beta expression in the myocardia of two young patients with type 1 diabetes mellitus and fatal diabetic ketoacidosis. Exp. Mol. Pathol. 96, 71-79 (2014).
15. Latz, E., Xiao, T. S., Stutz, A. Activation and regulation of the inflammasomes. Nat. Rev. Immunol. 13, 397-411 (2013).
16. Takeuchi, O., Akira, S. Pattern recognition receptors and inflammation. Cell 140, 805-820 (2010).
17. Mariathasan, S. et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440, 228-232 (2006).
18. Luheshi, N. M., Giles, J. A., Lopez-Castejon, G., Brough, D. Sphingosine regulates the NLRP3-inflammasome and IL-1b release from macrophages. Eur. J. Immunol. 42, 716-725 (2012).
19. Pétrilli, V. et al. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ. 14, 1583-1589 (2007).
20. Ehses, J. A. et al. Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet. Diabetologia 53, 1795-1806 (2010).
21. Mersmann, J. et al. Toll-like receptor 2 signaling triggers fatal arrhythmias upon myocardial ischemia-reperfusion. Crit. Care Med. 38, 1927-1932 (2010).
22. Dasu, M. R. et al. TLR2 expression and signaling-dependent inflammation impair wound healing in diabetic mice. Lab. Invest. 90, 1628-1636 (2010).
23. Higashikuni, Y. et al. Toll-like receptor-2 mediates adaptive cardiac hypertrophy in response to pressure overload through interleukin-1b upregulation via nuclear factor kB activation. J. Am. Heart Assoc. 2, e000267 (2013).
24. Gonano, L. A. et al. Calcium-calmodulin kinase II mediates digitalis-induced arrhythmias. Circ. Arrhythm. Electrophysiol. 4, 947-957 (2011).
25. Bassani, R. A., Bers, D. M. Rate of diastolic Ca release from the sarcoplasmic reticulum of intact rabbit and rat ventricular myocytes. Biophys. J. 68, 2015-2022 (1995).
26. Ferraz, S. A., Bassani, J. W., Bassani, R. A. Rest-dependence of twitch amplitude and sarcoplasmic reticulum calcium content in the developing rat myocardium. J. Mol. Cell. Cardiol. 33, 711-722 (2001).
27. Monnerat-Cahli, G. et al. Toll-like receptor 4 activation promotes cardiac arrhythmias by decreasing the transient outward potassium current (Ito) through an IRF3-dependent and MyD88-independent pathway. J. Mol. Cell. Cardiol. 76, 116-125 (2014).
28. Bassani, J. W., Bassani, R. A., Bers, D. M. Relaxation in rabbit and rat cardiac cells: species-dependent differences in cellular mechanisms. J. Physiol. 476, 279-293 (1994).
29. Erickson, J. R. et al. Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation. Nature 502, 372-376 (2013).
30. Luo, M. et al. Diabetes increases mortality after myocardial infarction by oxidizing CaMKII. J. Clin. Invest. 123, 1262-1274 (2013).
31. Singh, M. V. et al. MyD88 mediated inflammatory signaling leads to CaMKII oxidation, cardiac hypertrophy and death after myocardial infarction. J. Mol. Cell. Cardiol. 52, 1135-1144 (2012).
32. Khoo, M. S. et al. Calmodulin kinase II activity is required for normal atrioventricular nodal conduction. Heart Rhythm 2, 634-640 (2005).
33. van Rooijen, N., Hendrikx, E. Liposomes for specific depletion of macrophages from organs and tissues. Methods Mol. Biol. 605, 189-203 (2010).
34. Epelman, S. et al. Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. Immunity 40, 91-104 (2014).
35. Coll, R. C. et al. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat. Med. 21, 248-255 (2015).
36. Laliberte, R. E. et al. Glutathione S-transferase omega 1-1 is a target of cytokine release inhibitory drugs and may be responsible for their effect on interleukin-1beta posttranslational processing. J. Biol. Chem. 278, 16567-16578 (2003).
37. Perregaux, D. G. et al. Identification and characterization of a novel class of interleukin-1 post-translational processing inhibitors. J. Pharmacol. Exp. Ther. 299, 187-197 (2001).
38. Frangogiannis, N. G. Interleukin-1 in cardiac injury, repair, remodelling: pathophysiologic and translational concepts. Discoveries (Craiova) 3, e41 (2015).
39. Grishman, E. K., White, P. C., Savani, R. C. Toll-like receptors, the NLRP3 inflammasome, interleukin-1beta in the development and progression of type 1 diabetes. Pediatr. Res. 71, 626-632 (2012).
40. Lee, H. M. et al. Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes. Diabetes 62, 194-204 (2013).
41. Vandanmagsar, B. et al. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat. Med. 17, 179-188 (2011).
42. Dasu, M. R., Devaraj, S., Jialal, I. High glucose induces IL-1beta expression in human monocytes: mechanistic insights. Am. J. Physiol. Endocrinol. Metab. 293, E337-E346 (2007).
43. Tsan, M. F., Gao, B. Endogenous ligands of toll-like receptors. J. Leukoc. Biol. 76, 514-519 (2004).
44. Schroder, K., Zhou, R., Tschopp, J. The NLRP3 inflammasome: a sensor for metabolic danger? Science 327, 296-300 (2010).
45. Devaraj, S., Jialal, I., Yun, J. M., Bremer, A. Demonstration of increased tolllike receptor 2 and toll-like receptor 4 expression in monocytes of type 1 diabetes mellitus patients with microvascular complications. Metabolism 60, 256-259 (2011).
46. Devaraj, S. et al. Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state. J. Clin. Endocrinol. Metab. 93, 578-583 (2008).
47. Perez, F. et al. Plasma levels of interleukin-1beta, interleukin-2 and interleukin-4 in recently diagnosed type 1 diabetic children and their association with beta-pancreatic autoantibodies. Rev. Med. Chil. 132, 413-420 (2004).
48. Lopez-Izquierdo, A. et al. The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization. Am. J. Physiol. Heart Circ. Physiol. 306, H747-H754 (2014).
49. Bradshaw, E. M. et al. Monocytes from patients with type 1 diabetes spontaneously secrete proinflammatory cytokines inducing Th17 cells. J. Immunol. 183, 4432-4439 (2009).
50. Sordillo, P. P., Sordillo, D. C., Helson, L. Review: the prolonged QT interval: role of pro-inflammatory cytokines, reactive oxygen species and the ceramide and sphingosine-1 phosphate pathways. In Vivo 29, 619-636 (2015).
51. Li, Y. H., Rozanski, G. J. Effects of human recombinant interleukin-1 on electrical properties of guinea pig ventricular cells. Cardiovasc. Res. 27, 525-530 (1993).
52. Mitrokhin, V. M., Mladenov, M. I., Kamkin, A. G. IL-1 provokes electrical abnormalities in rat atrial myocardium. Int. Immunopharmacol. 28, 780-784 (2015).
53. Volders, P. G. et al. Cellular basis of biventricular hypertrophy and arrhythmogenesis in dogs with chronic complete atrioventricular block and acquired torsade de pointes. Circulation 98, 1136-1147 (1998).
54. Casis, O., Gallego, M., Iriarte, M., Sánchez-Chapula, J. A. Effects of diabetic cardiomyopathy on regional electrophysiologic characteristics of rat ventricle. Diabetologia 43, 101-109 (2000).
55. Rossing, P. et al. Prolonged QTc interval predicts mortality in patients with Type 1 diabetes mellitus. Diabet. Med. 18, 199-205 (2001).
56. Stettler, C. et al. QTc interval and resting heart rate as long-term predictors of mortality in type 1 and type 2 diabetes mellitus: a 23-year follow-up. Diabetologia 50, 186-194 (2007).
57. Sumpter, K. M., Adhikari, S., Grishman, E. K., White, P. C. Preliminary studies related to anti-interleukin-1beta therapy in children with newly diagnosed type 1 diabetes. Pediatr. Diabetes 12, 656-667 (2011).
58. Larsen, L. et al. Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells. Diabetologia 50, 779-789 (2007).
59. Kuida, K. et al. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 267, 2000-2003 (1995).
60. Lara-Tejero, M. et al. Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J. Exp. Med. 203, 1407-1412 (2006).
61. Bierhaus, A. et al. Methylglyoxal modification of Nav1. 8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy. Nat. Med. 18, 926-933 (2012).
62. Kim, H. Y. et al. Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity. Nat. Med. 20, 54-61 (2014).
63. Aurora, A. B. et al. Macrophages are required for neonatal heart regeneration. J. Clin. Invest. 124, 1382-1392 (2014).
64. Bassani, R. A., Ricardo, R. A., Bassani, J. W. Estimation of the fractional sarcoplasmic reticulum Ca2\+ release in intact cardiomyocytes using integrated Ca2\+ fluxes. Gen. Physiol. Biophys. 31, 401-408 (2012).
65. Monnerat-Cahli, G. et al. Bone marrow mesenchymal stromal cells rescue cardiac function in streptozotocin-induced diabetic rats. Int. J. Cardiol. 171, 199-208 (2014).
66. Curtis, M. J., Walker, M. J. Quantification of arrhythmias using scoring systems: an examination of seven scores in an in vivo model of regional myocardial ischaemia. Cardiovasc. Res. 22, 656-665 (1988).
67. Coutinho, D. C. O., Monnerat-Cahli, G., Ferreira, A. J., Medei, E. Activation of angiotensin-converting enzyme 2 improves cardiac electrical changes in ventricular repolarization in streptozotocin-induced hyperglycaemic rats. Europace 16, 1689-1696 (2014).
68. Monnerat-Cahli, G. et al. Toll-like receptor 4 activation promotes cardiac arrhythmias by decreasing the transient outward potassium current (Ito) through an IRF3-dependent and MyD88-independent pathway. J. Mol. Cell. Cardiol. 76, 116-125 (2014).
69. Kehat, I., Gepstein, A., Spira, A., Itskovitz-Eldor, J., Gepstein, L. Highresolution electrophysiological assessment of human embryonic stem cellderived cardiomyocytes: a novel in vitro model for the study of conduction. Circ. Res. 91, 659-661 (2002).
70. Dutra, F. F. et al. Hemolysis-induced lethality involves inflammasome activation by heme. Proc. Natl Acad. Sci. USA 111, E4110-E4118 (2014).