Increased persistent sodium current due to decreased pi3k signaling contributes to qt prolongation in the diabetic heart

Diabetes

Volumn 62, Issue 12, 2013, Pages 4257-4265

  Lu, Zhongju ^a   Jiang, Ya Ping ^a   Wu, Chia Yen C ^a   Ballou, Lisa M ^a   Liu, Shengnan ^a   Carpenter, Eileen S ^b   Rosen, Michael R ^a,c   Cohen, Ira S ^a   Lin, Richard Z ^a,d  

^a STONY BROOK UNIVERSITY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; ION CURRENT; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATCH CLAMP TECHNIQUE; PRIORITY JOURNAL; QT INTERVAL; QT PROLONGATION; SECOND MESSENGER; SODIUM CURRENT;

ACTION POTENTIALS; ANIMALS; ARRHYTHMIAS, CARDIAC; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; HEART CONDUCTION SYSTEM; MICE; MYOCYTES, CARDIAC; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; SODIUM;

EID: 84891767756     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0420     Document Type: Article

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