The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 306, Issue 5, 2014, Pages

  Lopez Izquierdo, Angelica ^a   Pereira, Renata O ^b,c   Wende, Adam R ^b,d   Punske, Bonnie B ^a   Dale Abel, E ^b,c   Tristani Firouzi, Martin ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Cardiac insulin receptor; Potassium channels; Ventricular repolarization

Indexed keywords

INSULIN; INSULIN RECEPTOR; MESSENGER RNA; POTASSIUM CHANNEL; KCNIP2 PROTEIN, RAT; KV CHANNEL INTERACTING PROTEIN; SHAL POTASSIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DIABETES MELLITUS; ELECTROCARDIOGRAPHY; GLUCOSE TOLERANCE; GLUCOSE TRANSPORT; HEART DEPOLARIZATION; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; HEART VENTRICLE REPOLARIZATION; MEMBRANE STEADY POTENTIAL; MOUSE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; QT PROLONGATION; SIGNAL TRANSDUCTION; STEADY STATE; ACTION POTENTIAL; ANIMAL; CARDIAC INSULIN RECEPTOR; DISEASE MODEL; DOWN REGULATION; GENETICS; HEART ARRHYTHMIA; HEART RATE; HEART VENTRICLE; KNOCKOUT MOUSE; METABOLISM; PATHOPHYSIOLOGY; TIME;

CARDIAC INSULIN RECEPTOR; POTASSIUM CHANNELS; VENTRICULAR REPOLARIZATION;

ACTION POTENTIALS; ANIMALS; ARRHYTHMIAS, CARDIAC; DIABETES COMPLICATIONS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ELECTROCARDIOGRAPHY; HEART RATE; HEART VENTRICLES; INSULIN; KV CHANNEL-INTERACTING PROTEINS; MICE; MICE, KNOCKOUT; MYOCYTES, CARDIAC; POTASSIUM CHANNELS; RECEPTOR, INSULIN; RNA, MESSENGER; SHAL POTASSIUM CHANNELS; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84899433206     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00849.2013     Document Type: Article

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